1PYG

structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 209
  • Norm. En. per Res.: -2.9746
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-96.4015	33.8139	-431.102	-493.6896	178	26	9	19105	2	68	100
A-C	0.0	10.1795	-22.8649	-12.6854	18	0	0	879	0	8	9
A-D	-36.3447	-51.0457	-148.758	-236.1484	100	8	0	5230	3	56	54
B-C	-20.2363	-66.9772	-147.815	-235.0286	107	14	0	5689	5	55	56
B-D	0.0	11.5068	-19.4022	-7.8954	17	0	0	863	0	8	11
C-D	-78.2799	29.6827	-573.085	-621.6822	209	33	12	24340	2	79	113

Interface residues

• A-B: ALA111B, ALA192A, ALA192B, ALA19A, ALA265B, ALA46A, ALA46B, ALA54B, ALA836B, ARG10A, ARG16A, ARG184A, ARG184B, ARG193A, ARG193B, ARG242A, ARG269A, ARG269B, ARG309A, ARG309B, ARG319A, ARG319B, ARG33A, ARG33B, ARG43A, ARG43B, ARG49A, ARG49B, ARG60A, ARG60B, ARG66A, ARG66B, ARG69A, ARG69B, ASN270A, ASN270B, ASN274A, ASN274B, ASN30A, ASN30B, ASN32A, ASN32B, ASN44A, ASN44B, ASP118B, ASP181A, ASP227A, ASP227B, ASP268A, ASP268B, ASP42A, ASP42B, ASP50A, ASP50B, ASP61A, ASP61B, CYS318A, CYS318B, GLN114B, GLN12A, GLN264A, GLN264B, GLN71A, GLN71B, GLN72A, GLN72B, GLU121B, GLU162A, GLU162B, GLU190A, GLU190B, GLU195A, GLU195B, GLU273A, GLU273B, GLU76A, GLY116B, GLY17A, GLY186A, GLY186B, GLY20A, GLY20B, GLY317A, GLY317B, GLY65A, GLY65B, HIS34A, HIS34B, HIS36A, HIS36B, HIS57A, HIS57B, HIS62A, HIS62B, HIS73A, HIS73B, ILE13A, ILE68A, ILE68B, LEU115B, LEU117B, LEU122B, LEU183A, LEU183B, LEU18A, LEU222B, LEU267A, LEU267B, LEU271A, LEU271B, LEU35A, LEU35B, LEU39A, LEU39B, LEU63A, LEU63B, LYS11A, LYS191A, LYS191B, LYS247A, LYS247B, LYS28B, LYS29B, LYS315A, LYS315B, LYS41A, LYS41B, MET224A, MET224B, PHE163A, PHE163B, PHE196A, PHE196B, PHE316A, PHE316B, PHE31B, PHE37A, PHE37B, PHE53A, PHE53B, PRO194A, PRO194B, PRO229A, PRO229B, PRO48A, PRO48B, SER14A, THR112B, THR197A, THR197B, THR228A, THR228B, THR25B, THR38A, THR38B, THR47A, THR47B, TRP189A, TRP189B, TRP67A, TRP67B, TYR113B, TYR185A, TYR185B, TYR51A, TYR51B, TYR75A, TYR75B, VAL15A, VAL24B, VAL266A, VAL266B, VAL40A, VAL40B, VAL45A, VAL45B, VAL64A, VAL64B
• A-C: ARG205A, ARG205C, ASP217A, ASP217C, ASP268C, GLN264A, GLN264C, GLU207A, GLU207C, LEU267A, LEU267C, LEU271A, VAL206A, VAL206C, VAL216A, VAL216C, VAL266A, VAL266C
• A-D: ALA435A, ALA435D, ALA728A, ALA728D, ARG426A, ARG426D, ARG427A, ARG427D, ARG438A, ARG438D, ARG720A, ARG720D, ARG724A, ARG724D, ARG770A, ARG770D, ASN727A, ASN727D, ASN763A, ASN763D, ASP423A, ASP423D, ASP722A, ASP722D, ASP733A, ASP733D, ASP756A, ASP756D, ASP769A, ASP769D, CYS171D, GLN175D, GLN264A, GLN264D, GLN723A, GLN723D, GLN729A, GLN729D, GLN754A, GLN754D, GLU382D, GLU432A, GLU432D, GLU433A, GLU433D, GLU730A, GLU730D, GLY172A, GLY172D, GLY434A, GLY434D, GLY725A, GLY725D, GLY748A, GLY748D, HIS614A, HIS614D, HIS767A, HIS767D, HIS768A, HIS768D, LEU267D, LEU721A, LEU721D, LEU757A, LEU757D, LYS437A, LYS437D, LYS617A, LYS617D, LYS621A, LYS621D, LYS753A, LYS753D, LYS759A, LYS759D, LYS772A, LYS772D, MET176A, MET176D, MET618A, MET618D, MET766A, MET766D, PRO752A, PRO752D, PRO755A, PRO755D, SER751A, SER751D, TRP174A, TRP174D, TYR726A, TYR726D, TYR732A, TYR732D, VAL266A, VAL266D, VAL436A, VAL436D
• B-C: ALA435B, ALA435C, ALA728B, ALA728C, ARG426B, ARG426C, ARG427B, ARG427C, ARG438B, ARG720B, ARG720C, ARG724B, ARG724C, ARG734B, ARG770B, ARG770C, ASN727B, ASN727C, ASN763B, ASN763C, ASP423B, ASP423C, ASP719B, ASP722B, ASP722C, ASP733B, ASP733C, ASP756B, ASP756C, ASP760C, ASP769B, ASP769C, CYS171B, CYS171C, GLN175B, GLN175C, GLN264B, GLN264C, GLN723B, GLN723C, GLN729B, GLN729C, GLN754B, GLN754C, GLU382B, GLU432B, GLU432C, GLU433B, GLU433C, GLU730B, GLU730C, GLY172B, GLY172C, GLY434B, GLY434C, GLY725B, GLY725C, GLY748B, GLY748C, HIS614B, HIS614C, HIS767B, HIS767C, HIS768B, HIS768C, LEU267B, LEU721B, LEU721C, LEU757B, LEU757C, LYS437B, LYS437C, LYS617B, LYS617C, LYS621B, LYS621C, LYS753B, LYS753C, LYS759B, LYS759C, LYS772B, LYS772C, MET176B, MET176C, MET618B, MET618C, MET766B, MET766C, PRO752B, PRO752C, PRO755B, PRO755C, SER747B, SER751B, SER751C, TRP174B, TRP174C, TYR726B, TYR726C, TYR732B, TYR732C, VAL266B, VAL266C, VAL422B, VAL422C, VAL436B, VAL436C
• B-D: ARG205B, ARG205D, ASP217B, ASP217D, ASP268D, GLN264B, GLN264D, GLU207B, GLU207D, LEU267B, LEU267D, LEU271B, LEU271D, VAL206B, VAL216B, VAL216D, VAL266D
• C-D: ALA111C, ALA111D, ALA192C, ALA192D, ALA19C, ALA19D, ALA265C, ALA265D, ALA46C, ALA46D, ALA54C, ALA54D, ARG10C, ARG10D, ARG16C, ARG16D, ARG184C, ARG184D, ARG193C, ARG193D, ARG242C, ARG242D, ARG269C, ARG269D, ARG309C, ARG309D, ARG319C, ARG319D, ARG33C, ARG33D, ARG43C, ARG43D, ARG49C, ARG49D, ARG60C, ARG60D, ARG66C, ARG66D, ARG69C, ARG69D, ASN270C, ASN270D, ASN274C, ASN274D, ASN30C, ASN30D, ASN32C, ASN32D, ASN44C, ASN44D, ASP118C, ASP118D, ASP181D, ASP227C, ASP227D, ASP268C, ASP268D, ASP42C, ASP42D, ASP50C, ASP50D, ASP61C, ASP61D, CYS318C, CYS318D, GLN114C, GLN114D, GLN12C, GLN12D, GLN264C, GLN264D, GLN71C, GLN71D, GLN72C, GLN72D, GLU110C, GLU110D, GLU121C, GLU121D, GLU190C, GLU190D, GLU195C, GLU195D, GLU273C, GLU273D, GLU76C, GLU76D, GLY116C, GLY116D, GLY17C, GLY17D, GLY186C, GLY186D, GLY20C, GLY20D, GLY317C, GLY317D, GLY65C, GLY65D, HIS34C, HIS34D, HIS36C, HIS36D, HIS57C, HIS57D, HIS62C, HIS62D, HIS73C, HIS73D, ILE13C, ILE13D, ILE68C, ILE68D, LEU115C, LEU115D, LEU117C, LEU117D, LEU122C, LEU122D, LEU183C, LEU183D, LEU18C, LEU18D, LEU267C, LEU267D, LEU271C, LEU271D, LEU35C, LEU35D, LEU39C, LEU39D, LEU63C, LEU63D, LYS11C, LYS11D, LYS191C, LYS191D, LYS247C, LYS247D, LYS28C, LYS28D, LYS29C, LYS29D, LYS315C, LYS315D, LYS41C, LYS41D, MET224C, MET224D, PHE163C, PHE163D, PHE196C, PHE196D, PHE316C, PHE316D, PHE31C, PHE31D, PHE37C, PHE37D, PHE53C, PHE53D, PRO188C, PRO188D, PRO194C, PRO194D, PRO229C, PRO229D, PRO249D, PRO48C, PRO48D, SER14C, SER14D, THR112C, THR112D, THR197C, THR197D, THR228C, THR228D, THR240C, THR25C, THR25D, THR38C, THR38D, THR47C, THR47D, TRP189C, TRP189D, TRP67C, TRP67D, TYR113C, TYR113D, TYR185C, TYR185D, TYR51C, TYR51D, TYR75C, TYR75D, VAL15C, VAL15D, VAL24C, VAL24D, VAL266C, VAL266D, VAL40C, VAL40D, VAL45C, VAL45D, VAL64C, VAL64D