1PVH

crystal structure of leukemia inhibitory factor in complex with gp130

• Total interactions analyzed: 6
• Total true interactions: 2
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 76
  • Norm. En. per Res.: -3.7299
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.4972	-48.4203	-187.932	-267.8495	76	4	2	7353	3	15	14
C-D	-32.7892	-55.8738	-194.806	-283.4691	76	10	2	7464	3	15	15

Interface residues

• A-B: ALA117B, ALA119B, ALA13B, ALA143A, ALA31B, ARG123B, ARG132B, ARG15B, ARG27B, ASN116B, ASN128B, ASN171A, ASN191A, ASN20B, ASN21B, ASN24B, ASP120B, ASP193A, CYS12B, CYS131B, CYS134B, CYS18B, GLN25B, GLN29B, GLN32B, GLU141A, GLU173A, GLY124B, GLY35B, HIS145A, HIS16B, HIS189A, HIS19B, ILE121B, ILE14B, ILE172A, ILE227A, ILE231A, ILE26B, LEU122B, LEU125B, LEU126B, LEU130B, LEU22B, LEU30B, LEU33B, LYS114B, LYS119A, LYS139A, LYS146A, PHE147A, PHE169A, PHE192A, PRO17B, PRO194A, SER127B, SER140A, SER165A, SER226A, SER229A, SER28B, SER36B, THR144A, THR166A, TRP142A, TRP175A, TYR164A, TYR168A, TYR196A, TYR84B, VAL129B, VAL167A, VAL170A, VAL174A, VAL195A, VAL230A
• C-D: ALA117D, ALA119D, ALA13D, ALA143C, ALA31D, ARG123D, ARG132D, ARG15D, ARG27D, ASN116D, ASN128D, ASN171C, ASN191C, ASN20D, ASN21D, ASN24D, ASP120D, ASP193C, CYS12D, CYS131D, CYS134D, CYS18D, GLN25D, GLN29D, GLN32D, GLU141C, GLU173C, GLY124D, GLY35D, HIS145C, HIS16D, HIS189C, HIS19D, ILE121D, ILE14D, ILE172C, ILE227C, ILE231C, ILE26D, LEU122D, LEU125D, LEU126D, LEU130D, LEU22D, LEU30D, LEU33D, LYS114D, LYS119C, LYS139C, LYS146C, PHE147C, PHE169C, PHE192C, PRO17D, PRO194C, SER127D, SER135D, SER140C, SER165C, SER226C, SER229C, SER28D, SER36D, THR144C, THR166C, TRP142C, TRP175C, TYR168C, TYR196C, TYR84D, VAL129D, VAL167C, VAL170C, VAL174C, VAL195C, VAL230C