1PG8

crystal structure of l-methionine alpha-, gamma-lyase

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 247
  • Norm. En. per Res.: -4.0308
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.4276	4.0498	-230.723	-267.1007	72	15	7	8376	0	8	7
A-C	-121.0922	-85.7868	-788.727	-995.606	247	30	17	31087	4	32	31
A-D	-71.3942	-144.7751	-384.173	-600.3423	164	17	9	16355	10	94	48
B-C	-53.9441	-143.198	-390.248	-587.3902	164	15	9	16369	11	94	47
B-D	-96.9018	-65.7312	-808.863	-971.496	247	31	17	30917	2	33	31
C-D	-44.8866	5.1689	-206.461	-246.1787	73	14	7	8243	0	8	7

Interface residues

• A-B: ALA253A, ALA253B, ALA27A, ALA27B, ALA36A, ALA36B, ARG257A, ARG257B, ASN64A, ASN64B, ASP20A, ASP20B, ASP23A, ASP23B, GLN22A, GLN22B, GLN34A, GLN34B, GLY25A, GLY25B, GLY26A, GLY26B, GLY56A, GLY56B, HIS16B, HIS24A, HIS24B, HIS250A, HIS250B, HIS57A, HIS57B, LEU254B, LEU28A, LEU28B, PHE38A, PHE38B, PHE40A, PHE40B, PHE58A, PHE58B, PRO21A, PRO21B, PRO249B, PRO30A, PRO30B, PRO31A, PRO31B, PRO41A, PRO41B, PRO65A, PRO65B, SER60A, THR35A, THR35B, THR37A, THR37B, THR39A, THR39B, THR42A, THR42B, THR66A, THR66B, TYR19A, TYR19B, TYR33A, TYR33B, TYR45A, TYR45B, VAL29A, VAL29B, VAL32A, VAL32B
• A-C: ALA119A, ALA119C, ALA209C, ALA221A, ALA221C, ALA245A, ALA245C, ALA252A, ALA252C, ALA331A, ALA331C, ALA338A, ALA338C, ALA348A, ALA348C, ALA352A, ALA352C, ALA36A, ALA36C, ALA47A, ALA47C, ALA48A, ALA48C, ALA51A, ALA51C, ALA87A, ALA87C, ALA92A, ALA92C, ARG102A, ARG102C, ARG326A, ARG326C, ARG327A, ARG327C, ARG337A, ARG337C, ARG61A, ARG61C, ASN330A, ASN330C, ASN64A, ASN64C, ASP105A, ASP105C, ASP218A, ASP218C, ASP241A, ASP241C, ASP251A, ASP251C, ASP343A, ASP343C, CYS116A, CYS116C, CYS49A, CYS49C, GLN237A, GLN237C, GLN349A, GLN349C, GLN34A, GLN34C, GLU127A, GLU127C, GLU345A, GLU345C, GLU44A, GLU44C, GLU53C, GLY104A, GLY104C, GLY115A, GLY115C, GLY124A, GLY124C, GLY126A, GLY126C, GLY129A, GLY129C, GLY217A, GLY217C, GLY238A, GLY238C, GLY244A, GLY244C, GLY323C, GLY325A, GLY325C, GLY46A, GLY46C, GLY52C, GLY89A, GLY89C, GLY91A, GLY91C, HIS122A, HIS122C, HIS123A, HIS123C, HIS216A, HIS216C, HIS250A, HIS250C, HIS350A, HIS350C, HIS356A, HIS356C, ILE125A, ILE125C, ILE219A, ILE219C, ILE322A, ILE322C, ILE62A, ILE62C, ILE93A, ILE93C, LEU100A, LEU100C, LEU101A, LEU101C, LEU121A, LEU121C, LEU236A, LEU236C, LEU239A, LEU239C, LEU247A, LEU247C, LEU254A, LEU254C, LEU332A, LEU332C, LEU341A, LEU341C, LEU347A, LEU347C, LEU86A, LEU86C, LEU97A, LEU97C, LYS211A, LYS211C, LYS240A, LYS240C, MET242A, MET242C, MET329A, MET329C, MET354A, MET354C, MET90A, MET90C, PHE118A, PHE118C, PHE120A, PHE120C, PHE128A, PHE128C, PHE328A, PHE328C, PHE335A, PHE335C, PHE38A, PHE38C, PHE40A, PHE40C, PHE50A, PHE50C, PHE58A, PHE58C, PRO103A, PRO103C, PRO249A, PRO249C, PRO351A, PRO351C, PRO41A, PRO41C, SER208A, SER208C, SER214A, SER214C, SER248A, SER248C, SER336A, SER336C, SER340A, SER340C, SER353A, SER353C, SER357A, SER357C, SER358A, SER358C, SER60A, SER60C, SER88A, SER88C, SER95A, SER95C, THR117A, THR117C, THR210A, THR210C, THR220A, THR220C, THR243A, THR243C, THR355A, THR355C, THR35A, THR35C, THR37A, THR37C, THR39A, THR39C, THR42A, THR42C, THR94A, THR94C, THR99A, THR99C, TRP98A, TRP98C, TYR114A, TYR114C, TYR33A, TYR33C, TYR359C, TYR45A, TYR45C, TYR59A, TYR59C, VAL130A, VAL130C, VAL246A, VAL246C, VAL32A, VAL32C, VAL339A, VAL339C, VAL374A, VAL374C, VAL43A, VAL43C
• A-D: ALA11A, ALA11D, ALA14A, ALA14D, ALA209A, ALA209D, ALA253A, ALA253D, ALA271A, ALA271D, ALA338A, ALA338D, ALA344A, ALA344D, ALA388A, ALA388D, ARG13A, ARG13D, ARG257A, ARG257D, ARG265A, ARG265D, ARG268A, ARG268D, ARG337A, ARG337D, ARG73A, ARG73D, ASN263A, ASN263D, ASN272A, ASN272D, ASP20A, ASP20D, ASP218A, ASP218D, ASP251A, ASP251D, ASP267A, ASP267D, ASP343A, ASP343D, ASP382A, ASP382D, ASP384A, ASP384D, ASP385A, ASP385D, ASP389A, GLN22A, GLN22D, GLN333A, GLN333D, GLN391A, GLN391D, GLN392A, GLN392D, GLU345A, GLU345D, GLU381A, GLU381D, GLY215A, GLY215D, GLY217A, GLY217D, GLY258A, GLY258D, GLY26A, GLY26D, GLY379A, GLY379D, GLY3A, GLY3D, GLY9A, GLY9D, HIS16A, HIS16D, HIS216A, HIS216D, HIS250A, HIS250D, HIS269A, HIS269D, HIS2A, HIS2D, ILE15A, ILE15D, ILE219A, ILE219D, ILE259A, ILE259D, ILE383A, ILE383D, LEU213A, LEU213D, LEU254A, LEU254D, LEU255A, LEU255D, LEU262A, LEU262D, LEU264A, LEU264D, LEU28A, LEU28D, LEU332A, LEU334A, LEU334D, LEU341D, LEU347A, LEU347D, LEU380A, LEU380D, LEU386A, LEU386D, LEU7A, LEU7D, LYS211A, LYS211D, LYS260A, LYS260D, LYS395A, LYS6A, LYS6D, MET256A, MET256D, MET266A, MET266D, PHE10A, PHE10D, PHE335A, PHE335D, PRO21A, PRO21D, PRO30A, PRO30D, PRO8A, PRO8D, SER214A, SER214D, SER336A, SER336D, SER340A, SER340D, SER346A, SER346D, SER4A, THR12A, THR12D, THR210A, THR261A, THR261D, TYR193A, TYR193D, TYR19A, TYR19D, TYR212A, TYR212D, VAL29A, VAL29D, VAL32A, VAL32D, VAL339A, VAL339D
• B-C: ALA11B, ALA11C, ALA14B, ALA14C, ALA209B, ALA209C, ALA253B, ALA253C, ALA271B, ALA271C, ALA338B, ALA338C, ALA344B, ALA344C, ALA388B, ALA388C, ARG13B, ARG13C, ARG257B, ARG257C, ARG265B, ARG265C, ARG268B, ARG268C, ARG337B, ARG337C, ARG73B, ARG73C, ASN263B, ASN263C, ASN272B, ASN272C, ASN5B, ASP20B, ASP20C, ASP218B, ASP218C, ASP251B, ASP251C, ASP267B, ASP267C, ASP343B, ASP343C, ASP382B, ASP382C, ASP384B, ASP384C, ASP385B, ASP385C, ASP389B, GLN22B, GLN22C, GLN333B, GLN333C, GLN391B, GLN392B, GLN392C, GLU345B, GLU345C, GLU381B, GLU381C, GLY215B, GLY215C, GLY217B, GLY217C, GLY258B, GLY258C, GLY26B, GLY26C, GLY379B, GLY379C, GLY3B, GLY9B, GLY9C, HIS16B, HIS16C, HIS216B, HIS216C, HIS250B, HIS250C, HIS269B, HIS269C, HIS2C, ILE15B, ILE15C, ILE219B, ILE219C, ILE259B, ILE259C, ILE383B, ILE383C, LEU213B, LEU213C, LEU254B, LEU254C, LEU255B, LEU255C, LEU262B, LEU262C, LEU264B, LEU264C, LEU28B, LEU28C, LEU334B, LEU334C, LEU341B, LEU341C, LEU347B, LEU347C, LEU380B, LEU380C, LEU386B, LEU386C, LEU387B, LEU7B, LEU7C, LYS211B, LYS211C, LYS260B, LYS260C, LYS395B, LYS6B, LYS6C, MET256B, MET256C, MET266B, MET266C, PHE10B, PHE10C, PHE335B, PHE335C, PRO21B, PRO21C, PRO30B, PRO30C, PRO8B, PRO8C, SER214B, SER214C, SER336B, SER336C, SER340B, SER340C, SER346B, SER346C, SER4B, THR12B, THR12C, THR210B, THR210C, THR261B, THR261C, TYR193B, TYR193C, TYR19B, TYR19C, TYR212B, TYR212C, VAL29B, VAL29C, VAL32B, VAL32C, VAL339B, VAL339C
• B-D: ALA119B, ALA119D, ALA221B, ALA221D, ALA245B, ALA245D, ALA252B, ALA252D, ALA331B, ALA331D, ALA338B, ALA338D, ALA348B, ALA348D, ALA352B, ALA352D, ALA36B, ALA36D, ALA47B, ALA47D, ALA48B, ALA48D, ALA51B, ALA51D, ALA87B, ALA87D, ALA92B, ALA92D, ARG102B, ARG102D, ARG326B, ARG326D, ARG327B, ARG327D, ARG337B, ARG337D, ARG61B, ARG61D, ASN330B, ASN330D, ASN64B, ASN64D, ASP105B, ASP105D, ASP218B, ASP218D, ASP241B, ASP241D, ASP251B, ASP251D, ASP343B, ASP343D, CYS116B, CYS116D, CYS49B, CYS49D, GLN237B, GLN237D, GLN349B, GLN349D, GLN34B, GLN34D, GLU127B, GLU127D, GLU345B, GLU345D, GLU44B, GLU44D, GLU53D, GLY104B, GLY104D, GLY115B, GLY115D, GLY124B, GLY124D, GLY126B, GLY126D, GLY129B, GLY129D, GLY217B, GLY217D, GLY238B, GLY238D, GLY244B, GLY244D, GLY323D, GLY325B, GLY325D, GLY46B, GLY46D, GLY89B, GLY89D, GLY91B, GLY91D, HIS122B, HIS122D, HIS123B, HIS123D, HIS216B, HIS216D, HIS250B, HIS250D, HIS350B, HIS350D, HIS356B, HIS356D, HIS57B, ILE125B, ILE125D, ILE219B, ILE219D, ILE322B, ILE322D, ILE62B, ILE62D, ILE93B, ILE93D, LEU100B, LEU100D, LEU101B, LEU101D, LEU121B, LEU121D, LEU236B, LEU236D, LEU239B, LEU239D, LEU247B, LEU247D, LEU254B, LEU254D, LEU332B, LEU332D, LEU341B, LEU341D, LEU347B, LEU347D, LEU86B, LEU86D, LEU97B, LEU97D, LYS211B, LYS211D, LYS240B, LYS240D, MET242B, MET242D, MET329B, MET329D, MET354B, MET354D, MET90B, MET90D, PHE118B, PHE118D, PHE120B, PHE120D, PHE128B, PHE128D, PHE328B, PHE328D, PHE335B, PHE335D, PHE38B, PHE38D, PHE40B, PHE40D, PHE50B, PHE50D, PHE58B, PHE58D, PRO103B, PRO103D, PRO249B, PRO249D, PRO351B, PRO351D, PRO41B, PRO41D, SER208B, SER208D, SER214B, SER214D, SER248B, SER248D, SER336B, SER336D, SER340B, SER340D, SER353B, SER353D, SER357B, SER357D, SER358B, SER358D, SER60B, SER60D, SER88B, SER88D, SER95B, SER95D, THR117B, THR117D, THR188D, THR210B, THR210D, THR220B, THR220D, THR243B, THR243D, THR355B, THR355D, THR35B, THR35D, THR37B, THR37D, THR39B, THR39D, THR42B, THR42D, THR94B, THR94D, THR99B, THR99D, TRP98B, TRP98D, TYR114B, TYR114D, TYR33B, TYR33D, TYR359B, TYR45B, TYR45D, TYR59B, TYR59D, VAL130B, VAL130D, VAL246B, VAL246D, VAL32B, VAL32D, VAL339B, VAL339D, VAL374B, VAL374D, VAL43B, VAL43D
• C-D: ALA253C, ALA253D, ALA27C, ALA27D, ALA36C, ALA36D, ARG257C, ARG257D, ASN64C, ASN64D, ASP20C, ASP20D, ASP23C, ASP23D, GLN22C, GLN22D, GLN34C, GLN34D, GLN54C, GLY25C, GLY25D, GLY26C, GLY26D, GLY56C, GLY56D, HIS16C, HIS24C, HIS24D, HIS250C, HIS250D, HIS57C, HIS57D, LEU28C, LEU28D, LYS260D, PHE38C, PHE38D, PHE40C, PHE40D, PHE58C, PHE58D, PRO21C, PRO21D, PRO249C, PRO30C, PRO30D, PRO31C, PRO31D, PRO41C, PRO41D, PRO65C, PRO65D, SER60C, THR35C, THR35D, THR37C, THR37D, THR39C, THR39D, THR42C, THR42D, THR66C, THR66D, TYR19C, TYR19D, TYR33C, TYR33D, TYR45C, TYR45D, VAL29C, VAL29D, VAL32C, VAL32D