1P2C

crystal structure analysis of an anti-lysozyme antibody

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 57
  • Norm. En. per Res.: -4.5455
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.1929	-48.2146	-519.624	-588.0316	190	16	10	19402	1	24	18
A-C	-9.8534	0.0	-80.4712	-90.3246	34	6	0	2953	0	3	4
A-F	-18.9713	-21.5055	-72.1807	-112.6574	38	8	0	3006	1	22	25
B-C	-24.3513	-93.916	-140.825	-259.0924	57	10	0	5427	6	9	7
D-E	-19.3278	-29.9283	-504.168	-553.4241	185	11	9	18913	1	25	19
D-F	-9.6051	0.0	-83.2689	-92.874	34	6	0	2999	0	3	4
E-F	-18.8985	-92.6187	-140.301	-251.8182	58	7	0	5516	6	9	7

Interface residues

• A-B: ALA130A, ALA397B, ALA428B, ALA471B, ARG211A, ARG45A, ARG516B, ARG96A, ASN137A, ASN138A, ASN157A, ASN161A, ASN210A, ASN32A, ASN361B, ASP165A, ASP167A, ASP170A, ASP1A, ASP1A5, ASP400B, CB9.75029-7.16244, CYS134A, CYS396B, CYS443B, CYS88A, GLN124A, GLN339B, GLN38A, GLN408B, GLN474B, GLN53A, GLN6A, GLN89A, GLN90A, GLU123A, GLU306B, GLU335B, GLU346B, GLU350B, GLU362B, GLU3A, GLU42A, GLU451B, GLY100A, GLY101A, GLY128A, GLY129A, GLY158A, GLY349B, GLY399B, GLY401B, GLY407B, GLY409B, GLY430B, GLY442B, GLY447B, GLY465B, GLY92A, GLY99A, HIS343B, HIS34A, HIS41A, HIS467B, ILE117A, ILE337B, ILE348B, ILE48A, ILE513B, ILE58A, LEU125A, LEU136A, LEU160A, LEU179A, LEU181A, LEU33A, LEU345B, LEU427B, LEU441B, LEU444B, LEU46A, LEU473B, LEU477B, LEU47A, LEU480B, LEU4A, LYS142A, LYS169A, LYS207A, LYS338B, LYS363B, LYS39A, LYS446B, LYS49A, LYS511B, LYS512B, MET175A, MET438B, MET55A, PHE118A, PHE135A, PHE139A, PHE209A, PHE402B, PHE469B, PHE87A, PHE98A, PRO119A, PRO120A, PRO426B, PRO429B, PRO44A, PRO452B, PRO470B, PRO515B, PRO95A, SER116A, SER121A, SER122A, SER127A, SER131A, SER162A, SER174A, SER176A, SER177A, SER208A, SER344B, SER40A, SER423B, SER437B, SER43A, SER463B, SER464B, SER475B, SER481B, SER482B, SER483B, SER56A, SER91A, SER93A, THR114A, THR126A, THR164A, THR172A, THR178A, THR180A, THR410B, THR411B, THR440B, THR468B, THR479B, THR485B, THR51A, THR97A, TRP163A, TRP333B, TRP336B, TRP347B, TRP35A, TRP406B, TRP457B, TRP491B, TRP94A, TYR173A, TYR186A, TYR359B, TYR360B, TYR36A, TYR394B, TYR395B, TYR403B, TYR405B, TYR425B, TYR478B, TYR50A, TYR86A, VAL115A, VAL132A, VAL133A, VAL159A, VAL393B, VAL404B, VAL424B, VAL439B, VAL445B, VAL466B, VAL472B, VAL484B, VAL514B, VAL85A
• A-C: ARG645C, ARG661C, ARG668C, ARG96A, ASN31A, ASN32A, ASN644C, ASN646C, ASP648C, ASP666C, GLN27A, GLN53A, GLN90A, GLY649C, GLY667C, GLY671C, GLY92A, HIS34A, ILE29A, ILE2A, PRO670C, PRO95A, SER28A, SER30A, SER650C, SER660C, SER91A, SER93A, THR647C, THR651C, THR669C, TRP94A, TYR50A, TYR653C
• A-F: ALA1510F, ALA1511F, ARG1514F, ARG1521F, ARG155A, ARG188A, ARG211A, ASN1519F, ASN1593F, ASN190A, ASN210A, ASN212A, ASP1518F, ASP151A, ASP184A, GLU154A, GLU185A, GLU187A, GLY1516F, GLY1522F, GLY152A, HIS1515F, HIS189A, ILE150A, LEU1517F, LEU1525F, LEU1629F, LYS149A, LYS1513F, LYS1596F, MET1512F, SER153A, SER1600F, SER191A, TYR1520F, TYR1523F, TYR192A, VAL1599F
• B-C: ALA642C, ALA682C, ARG398B, ARG645C, ARG668C, ASN644C, ASN665C, ASN674C, ASP356B, ASP400B, ASP652C, ASP666C, CYS664C, CYS680C, GLN641C, GLU335B, GLU350B, GLY349B, GLY354B, GLY399B, GLY401B, GLY649C, GLY654C, GLY667C, ILE334B, ILE351B, ILE678C, LEU352B, LEU683C, LEU684C, LYS601C, PHE329B, PHE402B, PRO353B, PRO670C, PRO679C, SER355B, SER357B, SER660C, SER681C, SER685C, THR328B, THR330B, THR331B, THR358B, THR640C, THR643C, THR651C, THR669C, TRP333B, TRP336B, TRP347B, TYR332B, TYR359B, TYR360B, TYR403B, TYR653C
• D-E: ALA1030D, ALA1297E, ALA1328E, ALA1371E, ARG1416E, ARG945D, ARG996D, ASN1037D, ASN1038D, ASN1061D, ASN1110D, ASN1261E, ASN932D, ASP1065D, ASP1067D, ASP1070D, ASP1300E, ASP1417E, ASP901D, CYS1034D, CYS1296E, CYS1343E, CYS988D, GLN1024D, GLN1239E, GLN1308E, GLN1374E, GLN906D, GLN938D, GLN953D, GLN989D, GLN990D, GLU1023D, GLU1206E, GLU1235E, GLU1246E, GLU1250E, GLU1262E, GLU1351E, GLU903D, GLU942D, GLY1000D, GLY1001D, GLY1028D, GLY1029D, GLY1058D, GLY1249E, GLY1299E, GLY1301E, GLY1307E, GLY1309E, GLY1330E, GLY1342E, GLY1347E, GLY1365E, GLY992D, GLY999D, HIS1243E, HIS1367E, HIS934D, HIS941D, ILE1017D, ILE1237E, ILE1248E, ILE1413E, ILE948D, ILE958D, LEU1025D, LEU1036D, LEU1060D, LEU1079D, LEU1081D, LEU1204E, LEU1245E, LEU1327E, LEU1341E, LEU1344E, LEU1373E, LEU1377E, LEU1380E, LEU904D, LEU933D, LEU946D, LEU947D, LYS1042D, LYS1069D, LYS1238E, LYS1263E, LYS1346E, LYS1411E, LYS1412E, LYS939D, LYS949D, MET1075D, MET1338E, MET955D, PHE1018D, PHE1035D, PHE1039D, PHE1109D, PHE1302E, PHE1369E, PHE987D, PHE998D, PRO1019D, PRO1020D, PRO1326E, PRO1329E, PRO1352E, PRO1370E, PRO1415E, PRO944D, PRO995D, SER1016D, SER1021D, SER1022D, SER1027D, SER1031D, SER1062D, SER1068D, SER1074D, SER1076D, SER1077D, SER1108D, SER1244E, SER1323E, SER1363E, SER1364E, SER1375E, SER1381E, SER1382E, SER1383E, SER940D, SER943D, SER991D, SER993D, THR1014D, THR1026D, THR1064D, THR1072D, THR1078D, THR1080D, THR1311E, THR1340E, THR1368E, THR1379E, THR1385E, THR951D, THR997D, TRP1063D, TRP1233E, TRP1236E, TRP1247E, TRP1306E, TRP1357E, TRP1391E, TRP935D, TRP994D, TYR1073D, TYR1086D, TYR1259E, TYR1260E, TYR1295E, TYR1303E, TYR1305E, TYR1325E, TYR1378E, TYR936D, TYR950D, TYR986D, VAL1015D, VAL1032D, VAL1033D, VAL1059D, VAL1264E, VAL1293E, VAL1304E, VAL1324E, VAL1339E, VAL1345E, VAL1366E, VAL1372E, VAL1384E, VAL1414E, VAL985D
• D-F: ARG1545F, ARG1561F, ARG1568F, ARG996D, ASN1544F, ASN1546F, ASN931D, ASN932D, ASP1548F, ASP1566F, GLN927D, GLN953D, GLN990D, GLY1549F, GLY1567F, GLY1571F, GLY992D, HIS934D, ILE902D, ILE929D, PRO1570F, PRO995D, SER1550F, SER1560F, SER928D, SER930D, SER991D, SER993D, THR1547F, THR1551F, THR1569F, TRP994D, TYR1553F, TYR950D
• E-F: ALA1542F, ALA1582F, ARG1298E, ARG1545F, ARG1568F, ASN1539F, ASN1544F, ASN1565F, ASN1574F, ASP1256E, ASP1300E, ASP1552F, ASP1566F, CYS1564F, CYS1580F, GLN1541F, GLU1235E, GLU1250E, GLY1249E, GLY1254E, GLY1299E, GLY1301E, GLY1549F, GLY1554F, GLY1567F, ILE1234E, ILE1251E, ILE1578F, LEU1252E, LEU1583F, LEU1584F, LYS1501F, PHE1229E, PHE1302E, PRO1253E, PRO1570F, PRO1579F, SER1255E, SER1257E, SER1560F, SER1581F, SER1585F, SER1586F, THR1228E, THR1230E, THR1231E, THR1258E, THR1540F, THR1543F, THR1551F, THR1569F, TRP1233E, TRP1247E, TYR1232E, TYR1259E, TYR1260E, TYR1303E, TYR1553F