1OZT

crystal structure of apo-h46r familial als mutant human cu, zn superoxide dismutase (cuznsod) to 2.5a resolution

• Total interactions analyzed: 28
• Total true interactions: 10
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 80
  • Norm. En. per Res.: -3.1239
• Hub Node: M(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
M-N	-36.4309	-1.358	-205.677	-243.4658	81	5	5	8260	0	8	6
M-G	0.0	6.3644	-19.7119	-13.3475	33	4	0	1043	0	3	5
M-L	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	1	0
N-H	-18.9382	20.6461	-19.702	-17.9941	26	4	0	548	0	2	4
G-H	-39.5199	-1.3572	-198.879	-239.7561	78	4	6	8024	0	8	6
H-J	0.0	0.0	-0.0112	-0.0112	2	0	0	2	0	0	0
K-L	-36.4731	-1.3579	-206.156	-243.987	80	6	6	8148	0	8	6
K-J	-5.058	-12.6423	-55.6076	-73.3079	40	2	0	2455	0	16	11
L-J	0.0	-1.7225	-0.0031	-1.7256	2	0	0	2	0	2	4
I-J	-40.0922	-1.4216	-208.398	-249.9118	80	4	6	8137	0	8	6

Interface residues

• M-N: ALA152M, ALA152N, ALA4M, ALA4N, ALA55M, ALA55N, ALA60M, ALA60N, ARG115M, ARG115N, ASN19M, ASN19N, ASN53M, ASN53N, ASP11M, ASP11N, ASP52M, ASP52N, CYS111M, CYS111N, CYS6M, CYS6N, GLN153M, GLN153N, GLU49M, GLU49N, GLY10N, GLY114M, GLY114N, GLY147M, GLY147N, GLY150M, GLY150N, GLY16M, GLY16N, GLY51M, GLY51N, GLY56M, GLY56N, GLY61M, GLY61N, HIS48M, HIS48N, ILE112M, ILE112N, ILE113M, ILE113N, ILE149M, ILE149N, ILE151M, ILE151N, ILE17M, ILE17N, ILE18M, ILE18N, LEU8M, LEU8N, LYS3M, LYS3N, LYS9M, LYS9N, PHE50M, PHE50N, PHE64M, PHE64N, PRO62M, PRO62N, SER59M, SER59N, THR116M, THR116N, THR2M, THR2N, THR54M, THR54N, VAL148M, VAL148N, VAL5M, VAL5N, VAL7M, VAL7N
• M-G: ARG115G, ASN26G, ASN26M, ASN65G, ASP109G, ASP109M, CYS111G, CYS111M, GLN22M, GLU24M, GLU49G, GLY108G, GLY108M, GLY27G, GLY27M, HIS110G, HIS110M, LEU67G, LEU67M, PHE64G, PRO28M, PRO66G, PRO66M, SER102G, SER102M, SER105G, SER105M, SER107G, SER107M, SER25G, SER25M, SER68M, VAL103M
• M-L: LYS23M, LYS91L
• N-H: ARG69N, ASN26H, ASN26N, ASP109H, ASP109N, CYS111H, CYS111N, GLU49N, GLY108H, GLY108N, HIS110H, HIS110N, LEU67H, LEU67N, PRO66H, PRO66N, SER102H, SER102N, SER105H, SER105N, SER107H, SER107N, SER25H, SER25N, VAL103H, VAL103N
• G-H: ALA152G, ALA152H, ALA4G, ALA4H, ALA55G, ALA55H, ALA60G, ALA60H, ARG115G, ARG115H, ASN19G, ASN19H, ASN53G, ASN53H, ASP52G, ASP52H, CYS111G, CYS111H, CYS6G, CYS6H, GLN153G, GLN153H, GLU49G, GLU49H, GLY114G, GLY114H, GLY147G, GLY147H, GLY150G, GLY150H, GLY16G, GLY16H, GLY51G, GLY51H, GLY56G, GLY56H, GLY61G, GLY61H, HIS48G, HIS48H, ILE112G, ILE112H, ILE113G, ILE113H, ILE149G, ILE149H, ILE151G, ILE151H, ILE17G, ILE17H, ILE18G, ILE18H, LEU8G, LEU8H, LYS3G, LYS3H, LYS9G, LYS9H, PHE50G, PHE50H, PHE64G, PHE64H, PRO62G, PRO62H, SER59G, SER59H, THR116G, THR116H, THR2G, THR2H, THR54G, THR54H, VAL148G, VAL148H, VAL5G, VAL5H, VAL7G, VAL7H
• H-J: ASN131J, LYS30H
• K-L: ALA152K, ALA152L, ALA4K, ALA4L, ALA55K, ALA55L, ALA60K, ALA60L, ARG115K, ARG115L, ASN19K, ASN19L, ASN53K, ASN53L, ASP11K, ASP11L, ASP52K, ASP52L, CYS111K, CYS111L, CYS6K, CYS6L, GLN153K, GLN153L, GLU49K, GLU49L, GLY114K, GLY114L, GLY147K, GLY147L, GLY150K, GLY150L, GLY16K, GLY16L, GLY51K, GLY51L, GLY56K, GLY56L, GLY61K, GLY61L, HIS48K, HIS48L, ILE112K, ILE112L, ILE113K, ILE113L, ILE149K, ILE149L, ILE151K, ILE151L, ILE17K, ILE17L, ILE18K, ILE18L, LEU8K, LEU8L, LYS3K, LYS3L, LYS9K, LYS9L, PHE50K, PHE50L, PHE64K, PHE64L, PRO62K, PRO62L, SER59K, SER59L, THR116K, THR116L, THR2K, THR2L, THR54K, THR54L, VAL148K, VAL148L, VAL5K, VAL5L, VAL7K, VAL7L
• K-J: ALA89K, ASP11J, ASP11K, ASP90J, ASP90K, ASP92J, ASP92K, GLN15J, GLN15K, GLU121J, GLU40J, GLU40K, GLY10J, GLY10K, GLY12J, GLY12K, GLY37J, GLY37K, GLY93J, GLY93K, HIS43J, HIS43K, LEU144J, LEU144K, LEU38J, LEU38K, LYS36J, LYS36K, LYS91J, LYS91K, LYS9J, LYS9K, PRO13J, PRO13K, THR39J, THR39K, VAL14J, VAL14K, VAL94J, VAL94K
• L-J: ASP11L, LYS91J
• I-J: ALA152I, ALA152J, ALA4I, ALA4J, ALA55I, ALA55J, ALA60I, ALA60J, ARG115I, ARG115J, ASN19I, ASN19J, ASN53I, ASN53J, ASP52I, ASP52J, CYS111I, CYS111J, CYS6I, CYS6J, GLN153I, GLN153J, GLU49I, GLU49J, GLY114I, GLY114J, GLY147I, GLY147J, GLY150I, GLY150J, GLY16I, GLY16J, GLY51I, GLY51J, GLY56I, GLY56J, GLY61I, GLY61J, HIS48I, HIS48J, ILE112I, ILE112J, ILE113I, ILE113J, ILE149I, ILE149J, ILE151I, ILE151J, ILE17I, ILE17J, ILE18I, ILE18J, LEU8I, LEU8J, LYS3I, LYS3J, LYS9I, LYS9J, PHE50I, PHE50J, PHE64I, PHE64J, PRO62I, PRO62J, SER59I, SER59J, THR116I, THR116J, THR2I, THR2J, THR54I, THR54J, THR58I, THR58J, VAL148I, VAL148J, VAL5I, VAL5J, VAL7I, VAL7J