1OXK

complex between ypd1 and sln1 response regulator domain in space group p3(2)

• Total interactions analyzed: 66
• Total true interactions: 27
• Strongest Interaction:
  • Chains: B-E
  • Int. Res.: 54
  • Norm. En. per Res.: -3.7657
• Hub Node: A(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-47.991	-36.9334	-155.743	-240.6674	76	25	6	7339	2	25	14
A-C	-17.8202	-6.199	-44.1734	-68.1926	32	3	0	1930	3	16	20
A-D	-16.3873	-17.076	-162.377	-195.8403	57	7	0	6470	2	19	20
A-E	-12.0253	-4.0004	-43.0985	-59.1241	30	1	0	1717	2	15	18
A-G	0.0	83.9709	-84.9376	-0.9667	74	1	1	4574	2	34	23
A-H	0.0	2.1394	-0.6799	1.4595	5	0	0	78	0	6	4
A-L	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	4	3
B-E	-19.2158	-28.7732	-155.359	-203.348	54	11	0	6325	1	19	22
B-G	0.0	5.653	-0.453	5.2	3	0	0	61	0	4	4
C-D	-49.8289	-33.4348	-160.07	-243.3338	73	27	5	7160	1	25	12
C-E	-14.1974	-5.8302	-39.279	-59.3066	31	4	0	1813	2	15	20
C-F	-23.4803	-18.1735	-145.976	-187.6299	58	15	0	6550	1	17	22
C-J	0.0	0.0	-0.0098	-0.0098	4	0	0	2	0	3	3
C-K	-7.3665	96.9056	-85.2558	4.2834	78	3	1	4573	3	35	24
C-L	0.0	4.3016	-0.1979	4.1037	3	0	0	40	0	3	4
D-K	0.0	3.5893	-0.1503	3.439	2	0	0	36	0	3	4
E-F	-44.6055	-41.0167	-170.511	-256.1332	77	23	6	7486	2	25	13
E-H	0.0	12.6243	-3.0908	9.5335	6	0	0	204	0	10	9
E-I	-5.1691	91.2739	-87.4864	-1.3816	76	2	1	4556	3	35	23
E-J	0.0	4.5276	-0.1942	4.3333	2	0	0	41	0	3	4
F-I	0.0	1.9073	-0.5636	1.3437	7	0	0	77	0	6	4
G-H	-46.3614	-39.3744	-152.684	-238.4198	76	21	5	7180	2	25	13
G-L	0.0	-6.326	-12.8048	-19.1308	14	0	0	713	0	6	6
H-I	-11.6387	7.7457	-33.6607	-37.5537	21	1	0	1178	1	6	6
I-J	-50.2748	-34.4746	-156.236	-240.9854	76	23	5	7139	1	25	13
J-K	0.0	-2.9962	-16.7437	-19.7399	16	0	0	812	0	6	6
K-L	-44.346	-35.6183	-153.711	-233.6753	73	21	5	7032	1	25	12

Interface residues

• A-B: ALA1174B, ALA39A, ALA71A, ALA72A, ARG1105B, ARG1199B, ARG90A, ASN1096B, ASN1099B, ASN10A, ASN1108B, ASN15A, ASN61A, ASP1095B, ASP1144B, ASP21A, ASP26A, ASP37A, CYS1119B, GLN1100B, GLN1146B, GLN34A, GLN38A, GLU1094B, GLU1101B, GLU1110B, GLU16A, GLU83A, GLY30A, GLY68A, GLY74A, HIS1097B, HIS64A, ILE1103B, ILE1197B, ILE13A, ILE17A, ILE18A, ILE32A, ILE33A, ILE36A, LEU1107B, LEU1109B, LEU1117B, LEU1202B, LEU14A, LEU31A, LEU62A, LEU66A, LEU73A, LEU75A, LYS1104B, LYS1149B, LYS1195B, LYS1198B, LYS1201B, LYS67A, MET1106B, MET1147B, MET20A, PHE1175B, PHE27A, PHE35A, PHE65A, PRO1148B, PRO1196B, PRO1200B, SER19A, SER28A, SER69A, SER70A, THR12A, THR42A, VAL1098B, VAL1102B, VAL1145B
• A-C: ARG90A, ARG90C, ASN134A, ASN134C, ASN55C, ASN61C, ASP132A, ASP132C, ASP60C, GLN86C, GLU133A, GLU133C, GLU53C, GLU58C, GLU93A, GLY89C, HIS64C, HIS94A, ILE136A, LEU140A, LEU56C, LEU59C, LEU62C, LYS54C, LYS91A, LYS91C, MET92A, MET92C, PHE95A, SER135A, THR57C, TYR137A
• A-D: ARG1160D, ARG1161D, ARG77A, ASN104A, ASN1180D, ASN98A, ASP108A, ASP1120D, ASP1126D, ASP1151D, ASP1162D, CYS1184D, GLN1122D, GLN76A, GLU101A, GLU1123D, GLU1183D, GLU1186D, GLU7A, GLY1121D, GLY1152D, HIS94A, ILE1159D, ILE4A, LEU102A, LEU106A, LEU1153D, LEU1154D, LEU1163D, LEU140A, LYS109A, LYS1129D, LYS1149D, LYS1157D, LYS1182D, LYS143A, MET1147D, MET1158D, MET1189D, PHE1125D, PHE95A, PHE96A, PRO1148D, PRO5A, PRO97A, SER107A, SER1155D, SER1187D, SER2A, SER6A, THR100A, THR105A, THR1156D, THR3A, TRP80A, VAL103A, VAL1150D
• A-E: ARG90A, ASN134A, ASN134E, ASN55A, ASN61A, ASP132A, ASP132E, ASP60A, GLN86A, GLU133A, GLU133E, GLU53A, GLU58A, GLU93E, GLY89A, HIS64A, HIS94E, ILE136E, LEU140E, LEU56A, LEU59A, LEU62A, LYS54A, LYS91A, LYS91E, MET92A, MET92E, PHE95E, THR57A, TYR137E
• A-G: ALA39A, ALA39G, ALA44A, ALA44G, ARG149A, ARG149G, ARG156A, ARG156G, ARG48A, ARG48G, ASN166A, ASN166G, ASP121A, ASP121G, ASP37A, ASP37G, ASP51A, ASP51G, GLN34A, GLN34G, GLN38A, GLN38G, GLN40A, GLN40G, GLN45A, GLN45G, GLN47A, GLN47G, GLN49A, GLN49G, GLU119A, GLU119G, GLU122A, GLU122G, GLU123A, GLU123G, GLU53A, GLU53G, GLY30A, GLY30G, GLY52A, GLY52G, ILE124A, ILE124G, ILE32A, ILE33A, ILE33G, ILE36A, ILE36G, LEU145A, LEU167A, LEU167G, LEU50A, LEU50G, LYS125A, LYS125G, LYS29A, LYS29G, LYS54A, MET46A, MET46G, PHE152G, PHE35A, PHE35G, PHE43A, PHE43G, PHE65A, PHE65G, THR165A, THR165G, THR41A, THR41G, THR42A, THR42G
• A-H: ARG48A, GLN49A, GLU53A, HIS1097H, VAL1098H
• A-L: LYS1134L, LYS125A
• B-E: ARG1160B, ARG1161B, ARG77E, ARG84E, ASN104E, ASN98E, ASP108E, ASP1151B, ASP1162B, CYS1184B, GLN1122B, GLN76E, GLU101E, GLU1123B, GLU1183B, GLU1186B, GLU7E, GLY1121B, GLY1152B, GLY1164B, HIS94E, ILE1159B, ILE4E, LEU102E, LEU106E, LEU1153B, LEU1154B, LEU1163B, LYS109E, LYS1129B, LYS1149B, LYS1157B, LYS143E, MET1147B, MET1158B, MET1189B, PHE1125B, PHE95E, PHE96E, PRO1148B, PRO5E, PRO97E, SER107E, SER1155B, SER1187B, SER2E, SER6E, THR100E, THR105E, THR1156B, THR3E, TRP80E, VAL103E, VAL1150B
• B-G: ARG48G, HIS1097B, VAL1098B
• C-D: ALA1174D, ALA39C, ALA71C, ALA72C, ARG1105D, ARG1199D, ARG90C, ASN1096D, ASN1099D, ASN10C, ASN1108D, ASN15C, ASN61C, ASP1095D, ASP1144D, ASP21C, ASP26C, ASP37C, CYS1119D, GLN1100D, GLN1146D, GLN34C, GLN38C, GLU1094D, GLU1101D, GLU1110D, GLU16C, GLU83C, GLY30C, GLY68C, GLY74C, HIS1097D, HIS64C, ILE1103D, ILE1197D, ILE13C, ILE17C, ILE18C, ILE32C, ILE33C, ILE36C, LEU1107D, LEU1109D, LEU1202D, LEU14C, LEU31C, LEU66C, LEU73C, LEU75C, LYS1104D, LYS1195D, LYS1198D, LYS1201D, LYS67C, MET1106D, MET1147D, MET20C, PHE1175D, PHE27C, PHE35C, PHE65C, PRO1148D, PRO1196D, PRO1200D, SER19C, SER28C, SER69C, SER70C, THR12C, THR42C, VAL1098D, VAL1102D, VAL1145D
• C-E: ARG90C, ARG90E, ASN134C, ASN134E, ASN55E, ASN61E, ASP132C, ASP132E, ASP60E, GLN86E, GLU133C, GLU133E, GLU53E, GLU58E, GLU93C, GLY89E, HIS64E, HIS94C, ILE136C, LEU140C, LEU56E, LEU59E, LEU62E, LYS54E, LYS91C, LYS91E, MET92C, MET92E, PHE95C, THR57E, TYR137C
• C-F: ARG1160F, ARG1161F, ARG77C, ARG84C, ASN104C, ASN1180F, ASN98C, ASP108C, ASP1120F, ASP1126F, ASP1151F, ASP1162F, CYS1184F, GLN1122F, GLN76C, GLU101C, GLU1123F, GLU1183F, GLU1186F, GLU7C, GLY1121F, GLY1152F, GLY1164F, HIS94C, ILE1159F, ILE4C, LEU102C, LEU106C, LEU1153F, LEU1154F, LEU1163F, LYS109C, LYS1129F, LYS1149F, LYS1157F, LYS1182F, LYS143C, MET1147F, MET1158F, MET1189F, PHE1125F, PHE95C, PHE96C, PRO1148F, PRO5C, PRO97C, SER107C, SER1155F, SER1187F, SER2C, SER6C, THR100C, THR105C, THR1156F, THR3C, TRP80C, VAL103C, VAL1150F
• C-J: GLU1130J, GLU123C, LYS1134J, LYS125C
• C-K: ALA39C, ALA39K, ALA44C, ALA44K, ARG149C, ARG149K, ARG156C, ARG156K, ARG48C, ARG48K, ASN116C, ASN166C, ASN166K, ASP120C, ASP120K, ASP121C, ASP121K, ASP26K, ASP37C, ASP37K, ASP51C, ASP51K, GLN34C, GLN34K, GLN38C, GLN38K, GLN40C, GLN40K, GLN45C, GLN45K, GLN47C, GLN47K, GLN49C, GLN49K, GLU119C, GLU119K, GLU122C, GLU122K, GLU123C, GLU123K, GLU53C, GLY30C, GLY30K, GLY52C, GLY52K, ILE124C, ILE124K, ILE33C, ILE33K, ILE36C, ILE36K, LEU145C, LEU145K, LEU167C, LEU167K, LEU50C, LEU50K, LYS125C, LYS125K, LYS153C, LYS153K, LYS29C, LYS29K, LYS54C, MET46C, MET46K, PHE152C, PHE152K, PHE43C, PHE43K, PHE65C, PHE65K, THR165C, THR165K, THR41C, THR41K, THR42C, THR42K
• C-L: ARG48C, GLU53C, HIS1097L
• D-K: ARG48K, HIS1097D
• E-F: ALA1174F, ALA39E, ALA71E, ALA72E, ARG1105F, ARG1199F, ARG90E, ASN1096F, ASN1099F, ASN10E, ASN1108F, ASN15E, ASN61E, ASP1095F, ASP1144F, ASP21E, ASP26E, ASP37E, CYS1119F, GLN1100F, GLN1146F, GLN34E, GLN38E, GLU1094F, GLU1101F, GLU1110F, GLU16E, GLU58E, GLU83E, GLY30E, GLY68E, GLY74E, HIS1097F, HIS64E, ILE1103F, ILE1197F, ILE13E, ILE17E, ILE18E, ILE32E, ILE33E, ILE36E, LEU1107F, LEU1109F, LEU1117F, LEU1202F, LEU14E, LEU31E, LEU62E, LEU66E, LEU73E, LEU75E, LYS1104F, LYS1149F, LYS1195F, LYS1198F, LYS1201F, LYS67E, MET1106F, MET1147F, MET20E, PHE1175F, PHE27E, PHE35E, PHE65E, PRO1148F, PRO1196F, PRO1200F, SER19E, SER28E, SER69E, SER70E, THR12E, THR42E, VAL1098F, VAL1102F, VAL1145F
• E-H: GLU1130H, GLU123E, ILE124E, LYS1134H, LYS125E, SER1133H
• E-I: ALA39E, ALA39I, ALA44E, ALA44I, ARG149E, ARG149I, ARG156E, ARG156I, ARG48E, ARG48I, ASN166E, ASN166I, ASP120I, ASP121E, ASP121I, ASP26E, ASP37E, ASP37I, ASP51E, ASP51I, GLN34E, GLN34I, GLN38E, GLN38I, GLN40E, GLN40I, GLN45E, GLN45I, GLN47E, GLN47I, GLN49E, GLN49I, GLU119E, GLU119I, GLU122E, GLU122I, GLU123E, GLU123I, GLU53I, GLY30E, GLY30I, GLY52E, GLY52I, ILE124E, ILE124I, ILE33E, ILE33I, ILE36E, ILE36I, LEU145E, LEU145I, LEU167E, LEU167I, LEU50E, LEU50I, LYS125E, LYS125I, LYS153E, LYS153I, LYS29E, LYS29I, LYS54I, MET46E, MET46I, PHE152E, PHE35E, PHE43E, PHE43I, PHE65E, PHE65I, THR165E, THR165I, THR41E, THR41I, THR42E, THR42I
• E-J: ARG48E, HIS1097J
• F-I: ARG48I, GLN49I, GLU1101F, GLU53I, GLY52I, HIS1097F, VAL1098F
• G-H: ALA1174H, ALA39G, ALA71G, ALA72G, ARG1105H, ARG1199H, ARG90G, ASN1096H, ASN1099H, ASN10G, ASN1108H, ASN15G, ASN61G, ASP1095H, ASP1144H, ASP21G, ASP26G, ASP37G, CYS1119H, GLN1100H, GLN1146H, GLN34G, GLN38G, GLU1094H, GLU1101H, GLU1110H, GLU16G, GLU83G, GLY30G, GLY68G, GLY74G, HIS1097H, HIS64G, ILE1103H, ILE1197H, ILE13G, ILE17G, ILE18G, ILE32G, ILE33G, ILE36G, LEU1107H, LEU1109H, LEU1117H, LEU1202H, LEU14G, LEU31G, LEU62G, LEU66G, LEU73G, LEU75G, LYS1104H, LYS1149H, LYS1195H, LYS1198H, LYS1201H, LYS67G, MET1106H, MET1147H, MET20G, PHE1175H, PHE27G, PHE35G, PHE65G, PRO1148H, PRO1196H, PRO1200H, SER19G, SER28G, SER69G, SER70G, THR12G, THR42G, VAL1098H, VAL1102H, VAL1145H
• G-L: ASN164G, ASP26G, GLU1130L, GLU1136L, GLY1135L, LEU1131L, LYS1089L, LYS1134L, LYS29G, SER1133L, THR1132L, THR165G, TYR162G, TYR163G
• H-I: ASN1114H, ASN164I, ASN166I, ASP21I, ASP26I, GLU1130H, GLU1136H, GLY1135H, ILE33I, LEU1131H, LEU167I, LYS1089H, LYS1134H, LYS29I, SER1087H, SER1133H, SER160I, THR1132H, THR165I, TYR162I, TYR163I
• I-J: ALA1174J, ALA39I, ALA71I, ALA72I, ARG1105J, ARG1199J, ARG90I, ASN1096J, ASN1099J, ASN10I, ASN1108J, ASN15I, ASN61I, ASP1095J, ASP1144J, ASP21I, ASP26I, ASP37I, CYS1119J, GLN1100J, GLN1146J, GLN34I, GLN38I, GLN86I, GLU1094J, GLU1101J, GLU1110J, GLU16I, GLU83I, GLY30I, GLY68I, GLY74I, HIS1097J, HIS64I, ILE1103J, ILE1197J, ILE13I, ILE17I, ILE18I, ILE32I, ILE33I, ILE36I, LEU1107J, LEU1109J, LEU1202J, LEU14I, LEU31I, LEU62I, LEU66I, LEU73I, LEU75I, LYS1104J, LYS1149J, LYS1195J, LYS1198J, LYS1201J, LYS67I, MET1106J, MET1147J, MET20I, PHE1175J, PHE27I, PHE35I, PHE65I, PRO1148J, PRO1196J, PRO1200J, SER19I, SER28I, SER69I, SER70I, THR12I, THR42I, VAL1098J, VAL1102J, VAL1145J
• J-K: ASN164K, ASN166K, ASP21K, ASP26K, GLU1130J, GLU1136J, GLY1135J, LEU1131J, LYS1089J, LYS1134J, LYS29K, SER1133J, THR1132J, THR165K, TYR162K, TYR163K
• K-L: ALA1174L, ALA39K, ALA71K, ALA72K, ARG1105L, ARG1199L, ASN1096L, ASN1099L, ASN10K, ASN1108L, ASN15K, ASN61K, ASP1095L, ASP1144L, ASP21K, ASP26K, ASP37K, CYS1119L, GLN1100L, GLN1146L, GLN34K, GLN38K, GLU1094L, GLU1101L, GLU1110L, GLU16K, GLU83K, GLY30K, GLY68K, GLY74K, HIS1097L, HIS64K, ILE1103L, ILE1197L, ILE13K, ILE17K, ILE18K, ILE32K, ILE33K, ILE36K, LEU1107L, LEU1109L, LEU1117L, LEU1202L, LEU14K, LEU31K, LEU66K, LEU73K, LEU75K, LYS1104L, LYS1195L, LYS1198L, LYS1201L, LYS67K, MET1106L, MET1147L, MET20K, PHE1175L, PHE27K, PHE35K, PHE65K, PRO1148L, PRO1196L, PRO1200L, SER19K, SER28K, SER69K, SER70K, THR12K, THR42K, VAL1098L, VAL1102L, VAL1145L