1OW7

paxillin ld4 motif bound to the focal adhesion targeting (fat) domain of the focal adhesion kinase

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 62
  • Norm. En. per Res.: -2.7096
• Hub Node: B(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-8.9648	-7.1203	-151.91	-167.9951	62	13	3	6898	0	15	9
A-D	0.0	-7.3957	-104.418	-111.8137	46	2	5	4953	0	13	10
B-C	-5.7134	15.8654	-133.602	-123.45	67	15	2	6326	2	18	19
B-E	-5.7709	-24.6257	-90.1365	-120.5331	47	22	5	5072	1	10	8
B-F	0.0	0.0	-0.2387	-0.2387	3	0	0	20	0	1	0
C-E	0.0	0.0	-0.2027	-0.2027	3	0	0	15	0	1	0
C-F	0.0	-31.305	-90.2392	-121.5442	46	13	5	4865	1	10	9

Interface residues

• A-B: ALA1041A, ALA1041B, ALA915B, ALA977B, ARG1042A, ARG1042B, ARG919A, ARG919B, ASN916A, ASN916B, ASN921A, ASN921B, ASP1039A, ASP1039B, ASP918A, ASP918B, ASP922A, ASP922B, ASP969B, GLN1040A, GLN1048A, GLU970A, GLU970B, GLY1047A, GLY1047B, HIS980B, ILE1038A, ILE1038B, ILE972A, ILE972B, LEU1043A, LEU1043B, LEU1046A, LEU1046B, LEU917A, LEU917B, LEU974A, LEU974B, LEU975A, LEU975B, LYS1044A, LYS1044B, LYS923A, LYS923B, MET1045A, MET1045B, PRO973A, PRO973B, PRO976A, PRO976B, SER920A, SER920B, SER978A, SER978B, THR1049A, THR914B, THR967B, THR971A, THR971B, THR979A, THR979B, VAL924B
• A-D: ALA1024A, ALA1026A, ALA1028A, ALA1031A, ALA10D, ALA934A, ARG3D, ARG919A, ASN1033A, ASN916A, ASN927A, ASP1030A, ASP1036A, ASP1039A, ASP6D, GLU4D, GLU7D, GLU926A, GLU937A, GLY930A, HIS1025A, ILE936A, LEU1021A, LEU1027A, LEU1035A, LEU12D, LEU5D, LEU8D, LEU917A, LEU931A, LYS1032A, LYS933A, MET938A, MET9D, SER11D, SER13D, SER939A, SER940A, THR2D, THR929A, TYR925A, VAL1029A, VAL924A, VAL928A, VAL932A, VAL935A
• B-C: ALA1023B, ALA1023C, ALA1026B, ALA1026C, ALA986B, ALA986C, ARG981B, ARG981C, ASN991B, ASN991C, ASN999B, ASN999C, ASP1030B, ASP1030C, ASP993B, ASP993C, GLN1006B, GLN1006C, GLN1013B, GLN1013C, GLN1019B, GLN1019C, GLN987B, GLN987C, GLU1015B, GLU1015C, GLU982B, GLU982C, GLU984B, GLU984C, GLU996B, GLU996C, GLY995B, GLY995C, LEU1003B, LEU1003C, LEU1012B, LEU1012C, LEU989B, LEU989C, LEU990B, LEU990C, LEU994B, LEU997B, LEU997C, LYS1000B, LYS1000C, LYS988B, LYS988C, MET1009B, MET1009C, MET985B, MET985C, SER1011B, SER1011C, SER992B, SER992C, THR1010B, THR1010C, THR1022B, THR1022C, TYR1007B, TYR1007C, TYR1016B, TYR1016C, VAL1008B, VAL1008C
• B-E: ALA10E, ALA960B, ALA966B, ARG3E, ARG962B, ASN991B, ASN999B, ASP6E, ASP969B, ASP993B, GLN1005B, GLN987B, GLU4E, GLU7E, GLU956B, GLU996B, GLY958B, GLY995B, ILE998B, LEU1027B, LEU12E, LEU5E, LEU8E, LEU959B, LEU961B, LEU964B, LEU965B, LEU990B, LEU994B, LEU997B, LYS1002B, LYS955B, LYS988B, MET1001B, MET1020B, MET953B, MET9E, PRO952B, SER11E, SER13E, SER992B, THR2E, THR963B, TYR950B, VAL951B, VAL954B, VAL957B
• B-F: GLN1006B, GLU4F, TYR1007B
• C-E: GLN1006C, GLU4E, TYR1007C
• C-F: ALA10F, ALA960C, ALA966C, ARG3F, ARG962C, ASN991C, ASN999C, ASP6F, ASP969C, ASP993C, GLN1005C, GLN987C, GLU4F, GLU7F, GLU956C, GLU996C, GLY958C, GLY995C, ILE998C, LEU12F, LEU5F, LEU8F, LEU959C, LEU961C, LEU964C, LEU965C, LEU990C, LEU994C, LEU997C, LYS1002C, LYS955C, LYS988C, MET1001C, MET1020C, MET953C, MET9F, PRO952C, SER11F, SER13F, SER992C, THR2F, THR963C, TYR950C, VAL951C, VAL954C, VAL957C