1OW6

paxillin ld4 motif bound to the focal adhesion targeting (fat) domain of the focal adhesion kinase

• Total interactions analyzed: 10
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 48
  • Norm. En. per Res.: -2.7248
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.5087	-2.3227	-115.961	-130.7924	48	5	3	5408	0	9	8
A-D	0.0	-6.5691	-38.6296	-45.1987	23	1	1	1777	0	5	3
B-C	-9.349	16.9914	-127.667	-120.0246	67	20	2	6402	1	18	20
B-F	0.0	0.0	-0.0309	-0.0309	3	0	0	6	0	1	0
C-F	0.0	-28.6678	-78.629	-107.2968	42	5	6	4243	1	8	6

Interface residues

• A-B: ALA1041A, ALA1041B, ALA915B, ARG1042A, ARG1042B, ARG919B, ASN916B, ASN921B, ASP1039A, ASP1039B, ASP918B, ASP922B, ASP969B, GLN1040A, GLN1048A, GLU970A, GLU970B, GLY1047A, GLY1047B, ILE1038A, ILE1038B, ILE972B, LEU1043A, LEU1043B, LEU1046A, LEU1046B, LEU917B, LEU974A, LEU974B, LEU975A, LEU975B, LYS1044A, LYS1044B, LYS923B, MET1045A, MET1045B, PRO973A, PRO973B, PRO976A, PRO976B, SER920B, SER978A, THR1049A, THR914B, THR967B, THR971A, THR971B, VAL924B
• A-D: ALA1024A, ALA1026A, ALA1028A, ALA1031A, ALA10D, ASN1033A, ASP1030A, ASP1036A, ASP1039A, ASP6D, HIS1025A, LEU1021A, LEU1027A, LEU1035A, LEU12D, LEU5D, LEU8D, LYS1032A, MET9D, SER11D, SER13D, THR2D, VAL1029A
• B-C: ALA1023B, ALA1023C, ALA1026B, ALA1026C, ALA986B, ALA986C, ARG981B, ARG981C, ASN991B, ASN991C, ASN999B, ASN999C, ASP1030B, ASP1030C, ASP993B, ASP993C, GLN1006B, GLN1006C, GLN1013B, GLN1013C, GLN1019B, GLN1019C, GLN987B, GLN987C, GLU1015B, GLU1015C, GLU982B, GLU982C, GLU984B, GLU984C, GLU996B, GLU996C, GLY995B, GLY995C, LEU1003B, LEU1003C, LEU1012B, LEU1012C, LEU989B, LEU989C, LEU990B, LEU990C, LEU994B, LEU997B, LEU997C, LYS1000B, LYS1000C, LYS988B, LYS988C, MET1009B, MET1009C, MET985B, MET985C, SER1011B, SER1011C, SER992B, SER992C, THR1010B, THR1010C, THR1022B, THR1022C, TYR1007B, TYR1007C, TYR1016B, TYR1016C, VAL1008B, VAL1008C
• B-F: GLN1006B, GLU4F, TYR1007B
• C-F: ALA10F, ALA960C, ALA966C, ARG3F, ARG962C, ASN991C, ASN999C, ASP6F, ASP969C, ASP993C, GLN1005C, GLN987C, GLU4F, GLU7F, GLU956C, GLU996C, GLY958C, GLY995C, ILE998C, LEU12F, LEU5F, LEU8F, LEU959C, LEU961C, LEU964C, LEU965C, LEU990C, LEU994C, LEU997C, LYS1002C, LYS955C, LYS988C, MET1001C, MET9F, PRO952C, SER11F, SER992C, THR2F, THR963C, VAL951C, VAL954C, VAL957C