1OQN

crystal structure of the phosphotyrosine binding domain (ptb) of mouse disabled 1 (dab1)

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 52
  • Norm. En. per Res.: -5.9233
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-46.7018	-99.8671	-146.5689	58	4	0	4492	5	33	26
A-C	-67.822	-21.0494	-210.095	-298.9664	52	24	3	7399	1	8	10
B-D	-61.7195	-23.921	-222.373	-308.0135	52	12	2	7490	1	9	10

Interface residues

• A-B: ALA1073A, ALA1073B, ALA1075A, ALA1075B, ARG1076A, ARG1076B, ASP1050A, ASP1050B, ASP1058A, ASP1063A, ASP1063B, ASP1119A, ASP1119B, ASP1122A, ASP1122B, CYS1061A, GLN1062A, GLN1062B, GLY1070A, GLY1070B, GLY1074A, GLY1074B, HIS1123A, HIS1123B, ILE1120A, ILE1120B, LEU1060A, LEU1060B, LEU1068A, LEU1068B, LYS1059A, LYS1059B, LYS1067A, LYS1067B, LYS1069A, LYS1069B, LYS1078A, LYS1078B, LYS1142A, LYS1142B, MET1065A, MET1065B, MET1066A, MET1066B, SER1053A, SER1053B, SER1064A, SER1064B, SER1077A, SER1077B, THR1121A, THR1121B, VAL1052A, VAL1052B, VAL1071A, VAL1071B, VAL1072A, VAL1072B
• A-C: ALA1054A, ALA1055A, ALA1109A, ALA1117A, ARG1056A, ARG1155A, ASN1135A, ASN1501C, ASN1505C, ASP1058A, ASP1156A, CYS1061A, CYS1130A, GLN1159A, GLN1166A, GLU1112A, GLU1133A, GLU1163A, GLU1504C, GLY1057A, GLY1093A, GLY1127A, GLY1131A, GLY1134A, GLY1502C, HIS1111A, HIS1136A, ILE1113A, ILE1116A, ILE1120A, ILE1151A, ILE1161A, LEU1154A, LEU1157A, LEU1160A, LEU1164A, LYS1059A, LYS1118A, LYS1132A, LYS1165A, LYS1509C, PHE1158A, PRO1506C, SER1114A, THR1507C, TYR1115A, TYR1128A, TYR1162A, TYR1503C, TYR1508C, VAL1110A, VAL1129A
• B-D: ALA1055B, ALA1109B, ALA1117B, ARG1056B, ARG1137B, ARG1155B, ASN1135B, ASN1501D, ASN1505D, ASP1058B, ASP1119B, ASP1156B, CYS1061B, CYS1130B, GLN1159B, GLN1166B, GLU1112B, GLU1133B, GLU1163B, GLU1504D, GLY1057B, GLY1093B, GLY1127B, GLY1131B, GLY1134B, GLY1502D, HIS1111B, HIS1136B, ILE1113B, ILE1116B, ILE1120B, ILE1151B, ILE1161B, LEU1154B, LEU1157B, LEU1160B, LEU1164B, LYS1118B, LYS1132B, LYS1165B, LYS1509D, PHE1158B, PRO1506D, SER1114B, THR1507D, TYR1115B, TYR1128B, TYR1162B, TYR1503D, TYR1508D, VAL1110B, VAL1129B