1OJY

decay accelerating factor (cd55): the structure of an intact human complement regulator.

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 118
  • Norm. En. per Res.: -2.3802
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-8.6489	-8.6489	14	2	0	428	0	8	6
A-C	-87.7998	9.4827	-202.551	-280.8681	118	23	1	8240	1	12	13
A-D	0.0	27.9101	-18.5833	9.3268	23	2	0	778	0	5	4
B-D	-92.753	4.9239	-194.421	-282.2502	119	23	2	8424	0	14	15
C-D	0.0	0.0	-1.1595	-1.1595	21	0	0	206	0	1	2

Interface residues

• A-B: ARG102B, ARG103B, ARG138B, ARG252A, ASN133B, ASN238A, ASN239A, ASP240A, GLU104B, GLU243A, PRO105B, PRO247A, SER106B, VAL237A
• A-C: ALA152A, ALA152C, ALA220A, ALA220C, ARG102A, ARG138A, ARG208A, ARG208C, ARG214A, ARG214C, ARG252C, ASN133A, ASN139A, ASN159A, ASN159C, ASN222A, ASN238C, ASN239C, ASP143A, ASP143C, ASP240C, CYS158A, CYS158C, CYS221A, CYS221C, CYS235C, GLN141A, GLN141C, GLN205A, GLN205C, GLN215A, GLN215C, GLU104A, GLU136A, GLU190A, GLU207A, GLU230C, GLU241C, GLU250C, GLY135A, GLY140A, GLY146A, GLY146C, GLY147A, GLY147C, GLY161A, GLY161C, GLY206A, GLY224A, GLY224C, GLY229C, GLY242C, GLY246C, HIS231A, HIS231C, ILE137A, ILE142A, ILE142C, ILE148A, ILE148C, ILE154A, ILE154C, ILE191A, ILE191C, ILE203A, ILE204A, ILE228C, ILE233C, LEU149A, LEU149C, LYS127A, LYS223A, LYS223C, MET227A, MET227C, PHE156A, PHE225A, PHE225C, PRO132A, PRO134A, PRO145A, PRO145C, PRO247C, PRO248C, PRO249C, SER155A, SER155C, SER157A, SER157C, SER216A, SER216C, SER232A, SER232C, SER245C, THR153C, THR160A, THR160C, THR218A, THR218C, THR226A, THR226C, THR236C, TRP181A, TRP244C, TYR162A, TYR162C, TYR211A, TYR213A, TYR213C, TYR219A, TYR219C, TYR234A, TYR234C, VAL144A, VAL144C, VAL217A, VAL217C, VAL237C
• A-D: ARG208D, ARG252A, ASP209D, GLN205D, GLN215D, GLU207D, GLU230A, GLU250A, GLY206D, GLY229A, GLY253A, HIS210D, ILE203D, ILE204D, ILE228A, LYS223D, MET227A, SER216D, SER245A, THR218D, THR226A, TYR211D, VAL217D
• B-D: ALA152B, ALA152D, ALA220B, ALA220D, ARG102B, ARG138B, ARG208B, ARG208D, ARG214B, ARG214D, ARG252D, ASN133B, ASN139B, ASN159B, ASN159D, ASN222B, ASN238D, ASN239D, ASP143B, ASP143D, ASP240D, CYS158B, CYS158D, CYS221B, CYS221D, CYS254D, GLN141B, GLN141D, GLN205B, GLN205D, GLN215B, GLN215D, GLU104B, GLU124B, GLU136B, GLU190B, GLU207B, GLU230D, GLU241D, GLU250D, GLY135B, GLY140B, GLY146B, GLY146D, GLY147B, GLY147D, GLY161B, GLY161D, GLY206B, GLY224B, GLY224D, GLY229D, GLY246D, HIS231B, HIS231D, ILE137B, ILE142B, ILE142D, ILE148B, ILE148D, ILE154B, ILE154D, ILE191B, ILE203B, ILE204B, ILE228D, ILE233D, LEU149B, LEU149D, LYS127B, LYS128D, LYS223B, LYS223D, MET227B, MET227D, PHE156B, PHE225B, PHE225D, PRO132B, PRO134B, PRO145B, PRO145D, PRO247D, PRO248D, PRO249D, SER155B, SER155D, SER157B, SER157D, SER216B, SER216D, SER232B, SER232D, SER245D, THR153D, THR160B, THR160D, THR218B, THR218D, THR226B, THR226D, THR236D, TRP181B, TRP244D, TYR162B, TYR162D, TYR211B, TYR213B, TYR213D, TYR219B, TYR219D, TYR234B, TYR234D, VAL144B, VAL144D, VAL217B, VAL217D, VAL237B, VAL237D
• C-D: ALA13C, ARG64C, ASN12C, ASP9C, GLN14C, GLN180D, GLU136D, GLU34C, GLU35C, GLU60C, GLY176D, LEU185D, LYS118C, PHE37C, PRO11C, PRO132D, PRO184D, SER175D, SER177D, SER36C, VAL10C