1OFP

crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 197
  • Norm. En. per Res.: -4.2725
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-142.9278	-49.6692	-649.093	-841.69	197	33	19	25832	5	82	56
A-C	0.0	1.0623	-15.0587	-13.9964	20	0	1	888	0	0	4
A-D	0.0	0.0	-66.9424	-66.9424	42	0	3	3141	0	4	1
B-C	0.0	0.0	-68.4403	-68.4403	41	0	3	3198	0	4	1
B-D	0.0	1.6823	-17.4344	-15.7521	22	2	1	990	0	0	4
C-D	-130.4441	-35.3153	-601.116	-766.8753	196	21	19	24314	6	92	59

Interface residues

• A-B: ALA169A, ALA169B, ALA179A, ALA179B, ALA191A, ALA191B, ALA217A, ALA218A, ALA218B, ALA219A, ALA219B, ALA233A, ALA233B, ALA234A, ALA234B, ALA32A, ALA32B, ALA51A, ARG180A, ARG180B, ARG188A, ARG188B, ARG249B, ARG24A, ARG24B, ARG55A, ARG55B, ASN124A, ASN124B, ASN130A, ASN130B, ASN133A, ASN133B, ASN135A, ASN135B, ASN241A, ASN241B, ASP125A, ASP125B, ASP161A, ASP161B, ASP170A, ASP170B, ASP213A, ASP22A, ASP22B, ASP29A, ASP29B, CYS244A, CYS244B, GLN166A, GLN166B, GLN185A, GLN185B, GLN38A, GLN38B, GLU111B, GLU183A, GLU183B, GLU189A, GLU189B, GLU21A, GLU21B, GLU242A, GLU242B, GLY137A, GLY137B, GLY193A, GLY193B, GLY226A, GLY226B, GLY231A, GLY231B, GLY240A, GLY240B, GLY27A, GLY27B, HIS187A, HIS187B, HIS220A, HIS220B, HIS222A, HIS222B, HIS223A, HIS223B, HIS230A, HIS230B, HIS243A, HIS243B, ILE123A, ILE123B, ILE134A, ILE134B, ILE163A, ILE163B, ILE235A, ILE235B, ILE25A, ILE25B, ILE59A, ILE59B, ILE62A, ILE62B, LEU138A, LEU138B, LEU160A, LEU160B, LEU168A, LEU168B, LEU171A, LEU171B, LEU186A, LEU186B, LEU190A, LEU190B, LEU194A, LEU194B, LEU26A, LEU26B, LEU31A, LEU31B, LEU48A, LEU48B, LYS112B, LYS120B, LYS136A, LYS136B, LYS229A, LYS229B, LYS239A, LYS239B, LYS52A, LYS52B, MET159A, MET159B, MET225A, MET225B, PHE132A, PHE132B, PHE196A, PHE196B, PHE224A, PHE224B, PRO113B, PRO165A, PRO165B, PRO197A, PRO197B, PRO30A, PRO30B, PRO34A, PRO34B, SER164A, SER164B, SER184A, SER184B, SER192A, SER192B, SER195A, SER195B, SER221A, SER221B, SER33A, SER33B, THR131A, THR131B, THR162A, THR162B, THR181A, THR181B, THR182A, THR182B, THR228A, THR228B, THR236A, THR236B, THR237A, THR237B, THR238A, THR238B, THR63A, TYR167A, TYR167B, TYR28A, TYR28B, VAL172A, VAL172B, VAL198A, VAL198B, VAL210A, VAL210B, VAL227A, VAL227B, VAL232A, VAL232B, VAL23A, VAL23B
• A-C: ALA233A, ALA233C, ALA234A, ALA234C, GLY231A, GLY231C, HIS230A, HIS230C, ILE235A, ILE235C, LEU36A, LEU36C, SER33A, SER33C, THR228A, THR228C, VAL232A, VAL232C, VAL39A, VAL39C
• A-D: ALA233A, ALA233D, ALA32A, ALA32D, ALA35A, ALA35D, ASN133A, ASN133D, ASN135A, ASN135D, ASP29A, ASP29D, GLN139A, GLN139D, GLN38A, GLN38D, GLN40A, GLN40D, GLY231A, GLY231D, HIS230A, HIS230D, LEU31A, LEU31D, LEU36A, LEU36D, LEU37A, LEU37D, LYS229A, LYS229D, PRO30A, PRO30D, PRO34A, PRO34D, SER33A, SER33D, TYR28A, TYR28D, VAL232A, VAL232D, VAL39A, VAL39D
• B-C: ALA233B, ALA32B, ALA32C, ALA35B, ALA35C, ASN133B, ASN133C, ASN135B, ASN135C, ASP29B, ASP29C, GLN139B, GLN139C, GLN38B, GLN38C, GLN40B, GLN40C, GLY231B, GLY231C, HIS230B, HIS230C, LEU31B, LEU31C, LEU36B, LEU36C, LEU37B, LEU37C, LYS229B, LYS229C, PRO30B, PRO30C, PRO34B, PRO34C, SER33B, SER33C, TYR28B, TYR28C, VAL232B, VAL232C, VAL39B, VAL39C
• B-D: ALA233B, ALA233D, ALA234B, ALA234D, GLY231B, GLY231D, HIS230B, HIS230D, ILE235B, ILE235D, LEU36B, LEU36D, LYS229B, LYS229D, SER33B, SER33D, THR228B, THR228D, VAL232B, VAL232D, VAL39B, VAL39D
• C-D: ALA169C, ALA169D, ALA179C, ALA179D, ALA191C, ALA191D, ALA218C, ALA218D, ALA219C, ALA219D, ALA233C, ALA233D, ALA234C, ALA234D, ALA32C, ALA32D, ALA51C, ALA51D, ARG142D, ARG180C, ARG180D, ARG188C, ARG188D, ARG24C, ARG24D, ARG55C, ARG55D, ASN124C, ASN124D, ASN130C, ASN130D, ASN133C, ASN133D, ASN135C, ASN135D, ASN241C, ASN241D, ASP125C, ASP125D, ASP161C, ASP161D, ASP170C, ASP170D, ASP213C, ASP22C, ASP22D, ASP29C, ASP29D, CYS244C, CYS244D, GLN166C, GLN166D, GLN185C, GLN185D, GLN38C, GLN38D, GLU111C, GLU183C, GLU183D, GLU189C, GLU189D, GLU20D, GLU21C, GLU21D, GLU242C, GLU242D, GLY137C, GLY137D, GLY193C, GLY193D, GLY226C, GLY226D, GLY231C, GLY231D, GLY240C, GLY240D, GLY27C, GLY27D, HIS187C, HIS187D, HIS220C, HIS220D, HIS222C, HIS222D, HIS223C, HIS223D, HIS230C, HIS230D, HIS243C, HIS243D, ILE123C, ILE123D, ILE134C, ILE134D, ILE163C, ILE163D, ILE235C, ILE235D, ILE25C, ILE25D, ILE59C, ILE59D, ILE62C, ILE62D, LEU138C, LEU138D, LEU160C, LEU160D, LEU168C, LEU168D, LEU171C, LEU171D, LEU186C, LEU186D, LEU190C, LEU190D, LEU194C, LEU194D, LEU26C, LEU26D, LEU31C, LEU31D, LEU48C, LEU48D, LYS120C, LYS120D, LYS136C, LYS136D, LYS229C, LYS229D, LYS239C, LYS239D, LYS52C, LYS52D, MET159C, MET159D, MET225C, MET225D, PHE132C, PHE132D, PHE196C, PHE196D, PHE224C, PHE224D, PRO165C, PRO165D, PRO197C, PRO197D, PRO30C, PRO30D, PRO34C, PRO34D, SER164C, SER164D, SER184C, SER184D, SER192C, SER192D, SER195C, SER195D, SER221C, SER221D, SER33C, SER33D, THR131C, THR131D, THR162C, THR162D, THR181C, THR181D, THR182C, THR182D, THR228C, THR228D, THR236C, THR236D, THR237C, THR237D, THR238C, THR238D, TYR167C, TYR167D, TYR28C, TYR28D, VAL172C, VAL172D, VAL198C, VAL198D, VAL210C, VAL210D, VAL227C, VAL227D, VAL232C, VAL232D, VAL23C, VAL23D