1O5O

crystal structure of uracil phosphoribosyltransferase (tm0721) from thermotoga maritima at 2.30 a resolution

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 181
  • Norm. En. per Res.: -4.5731
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-80.7305	-47.8032	-606.662	-735.1957	178	24	12	24805	5	65	72
A-C	-17.7026	-8.1245	-6.4723	-32.2994	15	2	0	537	4	12	16
A-D	-28.2475	59.2793	-318.514	-287.4822	103	14	8	12805	0	44	51
B-C	-35.4001	45.994	-316.113	-305.5191	106	9	7	12626	0	44	51
B-D	-15.5285	-9.6897	-8.2378	-33.4559	15	2	0	540	3	12	16
C-D	-126.9491	-73.3138	-627.461	-827.7238	181	25	13	25370	8	65	74

Interface residues

• A-B: ALA183A, ALA183B, ALA201A, ALA201B, ALA41A, ALA41B, ALA44A, ALA44B, ARG187A, ARG187B, ARG204A, ARG204B, ARG20A, ARG20B, ARG34A, ARG34B, ARG46A, ARG46B, ARG66A, ARG66B, ASN189A, ASN189B, ASN23A, ASN23B, ASN68A, ASN68B, ASN94A, ASN94B, ASP185A, ASP185B, ASP200A, ASP200B, ASP21A, ASP21B, ASP69A, ASP69B, ASP8A, ASP8B, CYS50A, CYS50B, GLU186A, GLU186B, GLU28A, GLU28B, GLU31A, GLU31B, GLU35A, GLU35B, GLU43A, GLU43B, GLU51A, GLU51B, GLU52A, GLU52B, GLU54A, GLU54B, GLU56A, GLU56B, GLU90A, GLU90B, GLY192B, GLY197A, GLY197B, GLY199A, GLY199B, GLY64A, GLY64B, GLY87A, GLY87B, HIS14A, HIS14B, HIS191A, HIS191B, HIS47A, HIS47B, HIS9A, HIS9B, ILE12A, ILE12B, ILE161A, ILE161B, ILE18A, ILE18B, ILE194A, ILE194B, ILE195A, ILE195B, ILE36A, ILE36B, ILE59A, ILE59B, ILE63A, ILE63B, ILE67A, ILE67B, ILE72A, ILE72B, ILE88A, ILE88B, LEU11A, LEU11B, LEU16A, LEU16B, LEU188A, LEU188B, LEU198A, LEU198B, LEU32A, LEU32B, LEU38A, LEU38B, LEU39A, LEU39B, LEU40A, LEU40B, LEU48A, LEU48B, LEU89A, LEU89B, LEU91A, LEU91B, LEU92A, LEU92B, LYS13A, LYS13B, LYS15A, LYS15B, LYS22A, LYS22B, LYS49A, LYS49B, LYS61A, LYS61B, LYS70A, LYS70B, MET133A, MET133B, MET19A, MET19B, PHE128A, PHE128B, PHE29A, PHE29B, PRO10A, PRO10B, PRO196A, PRO196B, PRO58A, PRO58B, PRO93A, PRO93B, THR17A, THR17B, THR24A, THR24B, THR37A, THR37B, THR45A, THR45B, THR57A, THR57B, THR60A, THR60B, THR62A, THR62B, TYR193A, TYR193B, TYR42A, TYR42B, TYR65A, TYR65B, VAL53A, VAL53B, VAL55A, VAL55B, VAL6B, VAL7A, VAL7B
• A-C: ARG34A, GLU28A, GLU28C, GLU31A, GLU31C, GLU35A, GLU35C, ILE18A, ILE18C, LEU32A, LEU32C, LYS15A, LYS15C, LYS27A, LYS27C
• A-D: ALA116A, ALA116D, ALA80A, ALA80D, ALA85A, ALA85D, ALA95A, ALA95D, ARG207A, ARG207D, ARG30A, ARG30D, ARG79A, ARG79D, ASN94A, ASN94D, ASP200A, ASP200D, ASP203A, ASP203D, ASP69A, ASP69D, ASP71A, ASP71D, ASP86A, ASP86D, GLU113A, GLU113D, GLU28A, GLU28D, GLU31A, GLU31D, GLU90A, GLU90D, GLY101A, GLY101D, GLY202A, GLY202D, GLY25A, GLY25D, GLY98A, GLY98D, HIS99A, HIS99D, ILE100D, ILE102A, ILE102D, ILE72A, ILE72D, LEU118A, LEU118D, LEU205A, LEU205D, LEU78A, LEU78D, LEU82A, LEU82D, LEU89A, LEU89D, LEU92A, LEU92D, LYS117A, LYS117D, LYS125A, LYS125D, LYS209A, LYS209D, LYS27A, LYS27D, LYS70A, LYS70D, PHE206A, PHE206D, PRO106A, PRO119A, PRO119D, PRO120A, PRO120D, PRO26A, PRO26D, PRO76A, PRO76D, PRO93A, PRO93D, SER96A, SER96D, THR208A, THR208D, TYR103A, TYR103D, TYR114A, TYR114D, TYR115A, TYR115D, VAL112A, VAL73A, VAL73D, VAL74A, VAL74D, VAL83A, VAL83D, VAL97A, VAL97D
• B-C: ALA116B, ALA116C, ALA80B, ALA80C, ALA85B, ALA85C, ALA95B, ALA95C, ARG207B, ARG207C, ARG30B, ARG30C, ARG34B, ARG79B, ARG79C, ASN94B, ASN94C, ASP200B, ASP200C, ASP203B, ASP203C, ASP69B, ASP69C, ASP71B, ASP71C, ASP86B, ASP86C, GLU113B, GLU113C, GLU28B, GLU28C, GLU31B, GLU31C, GLU90B, GLU90C, GLY101B, GLY101C, GLY202B, GLY202C, GLY25B, GLY25C, GLY98B, GLY98C, HIS99B, HIS99C, ILE100B, ILE100C, ILE102B, ILE102C, ILE72B, ILE72C, LEU118B, LEU118C, LEU121B, LEU205B, LEU205C, LEU78B, LEU78C, LEU82B, LEU82C, LEU89B, LEU89C, LEU92B, LEU92C, LYS117B, LYS117C, LYS125B, LYS125C, LYS209B, LYS209C, LYS27B, LYS27C, LYS70B, LYS70C, PHE206B, PHE206C, PRO106C, PRO119B, PRO119C, PRO120B, PRO120C, PRO26B, PRO26C, PRO76B, PRO76C, PRO93B, PRO93C, SER96B, SER96C, THR208B, THR208C, TYR103B, TYR103C, TYR114B, TYR114C, TYR115B, TYR115C, VAL112C, VAL73B, VAL73C, VAL74B, VAL74C, VAL83B, VAL83C, VAL97B, VAL97C
• B-D: ARG34B, ARG34D, GLU28B, GLU28D, GLU31B, GLU31D, GLU35B, GLU35D, ILE18B, LEU32B, LEU32D, LYS15B, LYS15D, LYS27B, LYS27D
• C-D: ALA183C, ALA183D, ALA201C, ALA201D, ALA41C, ALA41D, ALA44C, ALA44D, ARG187C, ARG187D, ARG204C, ARG204D, ARG20C, ARG20D, ARG34C, ARG34D, ARG46C, ARG46D, ARG66C, ARG66D, ASN189C, ASN189D, ASN23C, ASN23D, ASN68C, ASN68D, ASN94C, ASN94D, ASP185C, ASP185D, ASP200C, ASP200D, ASP21C, ASP21D, ASP69C, ASP69D, ASP8C, ASP8D, CYS50C, CYS50D, GLU186C, GLU186D, GLU28C, GLU28D, GLU31C, GLU31D, GLU35C, GLU35D, GLU43C, GLU43D, GLU51C, GLU51D, GLU52C, GLU52D, GLU54C, GLU54D, GLU56C, GLU56D, GLU90C, GLU90D, GLY192C, GLY192D, GLY197C, GLY197D, GLY199C, GLY199D, GLY64C, GLY64D, GLY87C, GLY87D, HIS14C, HIS14D, HIS191C, HIS191D, HIS47C, HIS47D, HIS9C, HIS9D, ILE12C, ILE12D, ILE161C, ILE161D, ILE18C, ILE18D, ILE194C, ILE194D, ILE195C, ILE195D, ILE36C, ILE36D, ILE59C, ILE59D, ILE63C, ILE63D, ILE67C, ILE67D, ILE72C, ILE72D, ILE88C, ILE88D, LEU11C, LEU11D, LEU16C, LEU16D, LEU188C, LEU188D, LEU198C, LEU198D, LEU32C, LEU32D, LEU38C, LEU38D, LEU39C, LEU39D, LEU40C, LEU40D, LEU48C, LEU48D, LEU89C, LEU89D, LEU91C, LEU91D, LEU92C, LEU92D, LYS13C, LYS13D, LYS15C, LYS15D, LYS22C, LYS22D, LYS49C, LYS49D, LYS61C, LYS61D, LYS70C, LYS70D, MET133C, MET133D, MET19C, MET19D, PHE128C, PHE128D, PHE29C, PHE29D, PRO10C, PRO10D, PRO196C, PRO196D, PRO58C, PRO58D, PRO93C, PRO93D, THR17C, THR17D, THR24C, THR24D, THR37C, THR37D, THR45C, THR45D, THR57C, THR57D, THR60C, THR60D, THR62C, THR62D, TYR180D, TYR193C, TYR193D, TYR42C, TYR42D, TYR65C, TYR65D, VAL53C, VAL53D, VAL55C, VAL55D, VAL5D, VAL6C, VAL7C, VAL7D