1O23

crystal structure of lactose synthase in the presence of udp-glucose

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 45
  • Norm. En. per Res.: -3.2376
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-13.3609	-9.4049	-119.387	-142.1528	68	2	2	5421	0	24	17
B-D	-50.6152	0.9332	-96.0089	-145.6909	45	6	4	4143	0	17	16
C-D	-9.7138	-12.8145	-127.838	-150.3663	66	2	1	5537	0	23	17

Interface residues

• A-B: ALA106A, ALA326B, ALA364B, ALA40A, ARG346B, ARG349B, ARG359B, ARG362B, ASN323B, ASN356B, ASN43A, ASN45A, ASP318B, ASP319B, ASP320B, ASP361B, ASP37A, ASP44A, CYS111A, CYS28A, GLN117A, GLN288B, GLN358B, GLN54A, GLU113A, GLU2A, GLU354B, GLU49A, GLY281B, GLY316B, GLY35A, GLY46A, HIS32A, HIS365B, ILE363B, LEU115A, LEU284B, LYS105A, LYS108A, LYS114A, LYS279B, LYS5A, MET110A, PHE280B, PHE290B, PHE31A, PHE360B, PRO109A, PRO285B, PRO355B, PRO357B, SER112A, SER283B, SER34A, THR33A, THR4A, TRP104A, TRP118A, TRP314B, TYR107A, TYR286B, TYR289B, TYR322B, TYR36A, VAL287B, VAL29A, VAL41A, VAL42A
• B-D: ALA221B, ALA623D, ARG387B, ARG789D, ASP397B, ASP799D, GLN386B, GLN788D, GLU159B, GLU238B, GLU384B, GLU561D, GLU640D, GLU786D, GLY168B, GLY570D, ILE394B, ILE796D, LEU167B, LEU383B, LEU390B, LEU569D, LEU785D, LEU792D, LYS156B, LYS241B, LYS393B, LYS558D, LYS643D, LYS795D, MET381B, PRO389B, PRO791D, THR392B, THR395B, THR794D, THR797D, TYR388B, TYR391B, TYR790D, TYR793D, VAL382B, VAL385B, VAL784D, VAL787D
• C-D: ALA442C, ALA508C, ALA766D, ARG736D, ARG748D, ARG751D, ARG761D, ARG764D, ASN445C, ASN447C, ASN725D, ASN758D, ASP439C, ASP446C, ASP720D, ASP721D, ASP722D, ASP763D, CYS430C, CYS513C, GLN456C, GLN519C, GLN690D, GLN760D, GLU404C, GLU451C, GLU515C, GLU756D, GLY437C, GLY718D, HIS434C, HIS767D, ILE765D, LEU517C, LEU686D, LYS407C, LYS507C, LYS510C, LYS516C, LYS681D, MET512C, PHE433C, PHE682D, PHE692D, PHE762D, PRO511C, PRO687D, PRO757D, PRO759D, SER436C, SER514C, SER685D, THR435C, THR768D, TRP506C, TRP520C, TRP716D, TYR438C, TYR509C, TYR688D, TYR691D, TYR724D, VAL431C, VAL443C, VAL444C, VAL689D