1O1F

molecular models of averaged rigor crossbridges from tomograms of insect flight muscle

• Total interactions analyzed: 325
• Total true interactions: 50
• Strongest Interaction:
  • Chains: D-K
  • Int. Res.: 13
  • Norm. En. per Res.: -1.348
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-47.9796	2.7298	1184.4	1139.1501	105	239	1	11968	0	15	11
A-C	-66.4497	-38.1238	562.024	457.4505	111	178	8	13178	3	42	42
A-H	0.0	0.0	-4.456	-4.456	7	0	0	283	0	0	0
A-4	-221.1435	50.1952	6166.06	5995.1117	145	1129	1	28465	0	42	46
A-6	-38.6517	0.874			7
B-C	0.0	0.0	-0.1398	-0.1398	7	0	0	47	0	0	2
B-H	0.0	0.0	-2.0695	-2.0695	9	0	0	132	0	4	7
B-I	0.0	0.0	-0.0469	-0.0469	2	0	0	13	0	4	4
D-E	-45.5797	2.1236	1376.32	1332.8639	111	323	4	14092	0	18	13
D-F	-133.518	-41.8315	1015.59	840.2404	98	244	5	13452	2	38	32
D-K	0.0	0.0	-17.5234	-17.5234	13	0	0	805	0	2	1
D-5	-220.8348	50.1335	3054.47	2883.7687	92	401	1	10470	0	34	38
D-7	-38.781	0.8762			7
E-F	0.0	0.0	-3.992	-3.992	15	0	0	386	0	4	6
E-K	-56.8637	47.0492	62.7767	52.9621	33	27	0	1381	0	7	19
G-H	-6.1112	7.9315	297.569	299.3893	123	198	7	14652	0	16	10
G-I	-38.8355	-4.5501	890.804	847.4184	118	220	5	15375	1	41	44
G-6	-220.3162	50.0092			41
G-8	-39.4481	0.8785			7
H-I	0.0	0.0	-0.0178	-0.0178	5	0	0	9	0	1	2
J-K	-32.2447	19.7049	1293.07	1280.5302	119	207	5	14017	0	15	9
J-L	-90.4886	5.7982	774.752	690.0616	108	234	4	13093	2	36	37
J-7	-220.8783	50.1256			41
J-V	-39.1227	0.8779			7
K-L	0.0	0.0	-0.1845	-0.1845	6	0	0	41	0	1	2
0-1	0.0	2.3775	-10.5251	-8.1476	42	0	0	651	3	22	13
0-2	-29.1051	-17.3733	1148.36	1101.8816	64	206	2	5619	0	25	17
1-2	0.0	2.3766	-10.5251	-8.1485	42	0	0	651	3	22	13
1-3	-29.0726	-17.3701	1149.49	1103.0473	64	206	2	5620	0	25	17
2-3	0.0	2.3782	-10.5268	-8.1486	42	0	0	649	3	22	13
2-4	-29.0632	-17.3635	1145.75	1099.3233	64	206	2	5618	0	25	17
3-4	0.0	2.3763	-10.5236	-8.1473	42	0	0	651	3	22	13
3-5	-29.0533	-17.3589	1152.53	1106.1178	62	205	2	5296	0	25	17
4-5	0.0	2.3778	-5.7633	-3.3854	33	0	0	399	3	19	10
4-6	-29.1023	-17.3634			11
5-6	0.0	2.3768			6
5-7	-29.0847	-17.3712			11
6-7	0.0	2.3771			6
6-8	-29.1141	-17.3626			11
7-8	0.0	2.3782			6
7-V	-29.0608	-17.3656			11
8-V	0.0	2.3772			6
8-W	-29.0961	-17.3596			11
V-W	0.0	2.3775			6
V-X	-29.0799	-17.3666			11
W-X	0.0	2.3767			6
W-Y	-29.0661	-17.3616			11
X-Y	0.0	2.3772			6
X-Z	-29.1007	-17.3708			11
Y-Z	0.0	2.3763			6

Interface residues

• A-B: ALA100B, ALA138B, ALA139B, ALA163B, ALA30B, ALA52B, ALA53B, ALA66B, ALA805A, ALA91B, ARG127B, ARG48B, ARG56B, ARG809A, ARG810A, ARG821A, ASN135B, ASN819A, ASN825A, ASP162B, ASP26B, ASP35B, ASP43B, ASP45B, ASP46B, ASP92B, CYS815A, GLN36B, GLN817A, GLU132B, GLU161B, GLU29B, GLU49B, GLU63B, GLU70B, GLU802A, GLU811A, GLU86B, GLY124B, GLY125B, GLY126B, GLY160B, GLY55B, GLY85B, GLY90B, HIS159B, HIS828A, ILE157B, ILE34B, ILE42B, ILE68B, ILE75B, ILE813A, ILE816A, ILE838A, ILE97B, LEU104B, LEU120B, LEU121B, LEU47B, LEU64B, LEU834A, LEU842A, LEU88B, LYS44B, LYS60B, LYS87B, LYS89B, MET136B, MET54B, MET67B, MET806A, MET824A, MET832A, MET83B, PHE101B, PHE128B, PHE140B, PHE27B, PHE51B, PHE80B, PHE814A, PHE823A, PHE835A, PHE836A, PHE84B, PRO830A, PRO840A, PRO93B, SER812A, SER822A, THR122B, THR123B, THR158B, THR50B, TRP829A, TRP831A, TYR155B, TYR818A, VAL156B, VAL33B, VAL59B, VAL820A, VAL826A, VAL96B
• A-C: ALA112C, ALA13C, ALA34C, ALA36C, ALA44C, ALA729A, ALA784A, ALA789A, ALA792A, ARG19C, ARG35C, ARG779A, ARG793A, ARG795A, ARG800A, ARG804A, ARG809A, ARG810A, ARG92C, ASN29A, ASN40C, ASN43C, ASN47C, ASP18C, ASP32C, ASP86C, ASP95C, ASP9C, CYS794A, GLN130C, GLN29C, GLN39C, GLN791A, GLN81C, GLU106C, GLU116C, GLU120C, GLU121C, GLU122C, GLU124C, GLU125C, GLU12C, GLU21A, GLU26A, GLU45C, GLU785A, GLU802A, GLU85C, GLU89C, GLU97C, GLY115C, GLY31C, GLY38C, GLY796A, GLY82C, GLY90C, HIS145C, ILE146C, ILE25A, ILE33C, ILE46C, ILE786A, ILE787A, LEU107C, LEU111C, LEU114C, LEU126C, LEU15C, LEU16C, LEU37C, LEU727A, LEU783A, LEU798A, LEU91C, LYS117C, LYS128C, LYS144C, LYS22A, LYS79C, LYS96C, MET103C, MET118C, MET127C, MET147C, MET799A, MET806A, PHE142C, PHE14C, PHE17C, PHE797A, PHE84C, PHE87C, PHE94C, PRO41C, SER148C, THR113C, THR119C, THR42C, THR788A, THR790A, THR83C, TYR803A, VAL110C, VAL123C, VAL143C, VAL149C, VAL726A, VAL801A, VAL807A, VAL88C, VAL93C
• A-H: GLU21H, GLU25H, ILE838A, LEU834A, LEU841A, PRO840A, THR22H
• A-4: ALA1384, ALA1444, ALA194, ALA224, ALA264, ALA2954, ALA3314, ALA3474, ALA412A, ALA545A, ALA630A, ALA651A, ALA74, ARG1474, ARG284, ARG3354, ARG654A, ASN2964, ASN410A, ASN599A, ASN656A, ASN658A, ASP14, ASP244, ASP254, ASP34, CYS540A, GLN3534, GLN3544, GLN647A, GLU1674, GLU24, GLU3344, GLU3614, GLU411A, GLU44, GLU524A, GLU527A, GLU537A, GLU538A, GLU539A, GLU557A, GLU605A, GLU629A, GLU631A, GLU655A, GLY1464, GLY1684, GLY204, GLY234, GLY3014, GLY3024, GLY3424, GLY3434, GLY407A, GLY409A, GLY531A, GLY628A, GLY632A, GLY633A, GLY634A, GLY635A, GLY638A, GLY639A, GLY643A, HIS558A, ILE1654, ILE3304, ILE3414, ILE3454, ILE526A, ILE532A, ILE535A, LEU1044, LEU1404, LEU1424, LEU3464, LEU3494, LEU525A, LEU536A, LEU554A, LEU596A, LEU652A, LEU84, LYS184, LYS3264, LYS3284, LYS3364, LYS544A, LYS636A, LYS637A, LYS640A, LYS641A, LYS642A, MET2994, MET3054, MET3554, MET530A, MET541A, PHE214, PHE3524, PHE533A, PHE542A, PHE550A, PHE646A, PRO274, PRO3324, PRO3334, PRO529A, PRO543A, SER1414, SER1454, SER3004, SER3384, SER3444, SER3484, SER3504, SER534A, SER549A, SER644A, SER645A, SER650A, THR1484, THR1494, THR3514, THR3584, THR414A, THR54, THR64, THR648A, TRP3404, TRP3564, TYR1334, TYR1434, TYR3374, TYR626A, VAL1394, VAL1524, VAL2984, VAL3394, VAL406A, VAL408A, VAL413A, VAL649A, VAL94
• A-6: ASN552A, ASP516, ASP556A, GLY486, LEU554A, LYS506, MET476
• B-C: ARG19C, GLU121C, GLY124B, GLY125B, GLY126B, THR122B, THR123B
• B-H: ALA53B, ASP20H, GLU21H, GLY55B, ILE24H, LEU57B, MET54B, PHE19H, THR82H
• B-I: HIS145I, LYS134B
• D-E: ALA100E, ALA139E, ALA163E, ALA30E, ALA52E, ALA53E, ALA66E, ALA805D, ALA91E, ARG127E, ARG48E, ARG56E, ARG809D, ARG810D, ARG821D, ASN135E, ASN819D, ASN825D, ASP162E, ASP26E, ASP35E, ASP43E, ASP45E, ASP46E, ASP65E, ASP92E, CYS815D, GLN36E, GLN817D, GLU119E, GLU132E, GLU161E, GLU29E, GLU49E, GLU62E, GLU63E, GLU70E, GLU802D, GLU811D, GLU86E, GLY124E, GLY125E, GLY126E, GLY160E, GLY55E, GLY85E, GLY90E, HIS159E, HIS828D, ILE153E, ILE157E, ILE34E, ILE42E, ILE68E, ILE75E, ILE813D, ILE816D, ILE838D, ILE97E, LEU104E, LEU120E, LEU121E, LEU47E, LEU64E, LEU834D, LEU841D, LEU842D, LEU88E, LYS44E, LYS60E, LYS87E, LYS89E, MET136E, MET54E, MET67E, MET806D, MET824D, MET832D, MET83E, PHE101E, PHE128E, PHE140E, PHE19E, PHE27E, PHE31E, PHE51E, PHE80E, PHE814D, PHE823D, PHE835D, PHE836D, PHE84E, PRO830D, PRO840D, PRO93E, SER812D, SER822D, THR122E, THR123E, THR129E, THR158E, THR50E, TRP829D, TRP831D, TYR818D, VAL156E, VAL33E, VAL59E, VAL820D, VAL826D, VAL96E
• D-F: ALA13F, ALA34F, ALA36F, ALA44F, ALA784D, ALA789D, ALA792D, ARG19F, ARG35F, ARG723D, ARG779D, ARG793D, ARG795D, ARG800D, ARG804D, ARG809D, ARG810D, ASN40F, ASN43F, ASN47F, ASN78F, ASP18F, ASP32F, ASP80F, ASP86F, ASP9F, CYS794D, GLN130F, GLN29F, GLN39F, GLN722D, GLN791D, GLN81F, GLU116F, GLU121F, GLU122F, GLU125F, GLU12F, GLU45F, GLU785D, GLU802D, GLU85F, GLU89F, GLY115F, GLY31F, GLY38F, GLY796D, GLY82F, GLY90F, HIS145F, ILE146F, ILE33F, ILE46F, ILE786D, ILE787D, LEU111F, LEU114F, LEU126F, LEU15F, LEU16F, LEU37F, LEU783D, LEU798D, LEU91F, LYS117F, LYS128F, LYS144F, LYS79F, MET118F, MET127F, MET147F, MET799D, MET806D, PHE142F, PHE14F, PHE17F, PHE68F, PHE797D, PHE84F, PHE87F, PRO41F, SER148F, THR119F, THR42F, THR788D, THR790D, THR83F, TYR803D, VAL110F, VAL123F, VAL143F, VAL149F, VAL30F, VAL726D, VAL801D, VAL807D, VAL88F, VAL93F
• D-K: GLU21K, GLU25K, ILE24K, ILE838D, LEU81K, LEU841D, LEU842D, LYS28K, PHE77K, PHE835D, PHE836D, PRO840D, THR22K
• D-5: ALA1385, ALA1445, ALA195, ALA225, ALA265, ALA545D, ALA630D, ALA651D, ALA75, ARG1475, ARG285, ARG3355, ARG654D, ASN410D, ASN656D, ASN658D, ASP15, ASP245, ASP255, ASP35, CYS540D, GLN3545, GLN647D, GLU1675, GLU25, GLU3345, GLU411D, GLU45, GLU537D, GLU538D, GLU539D, GLU605D, GLU629D, GLU631D, GLU655D, GLY1465, GLY1685, GLY205, GLY235, GLY407D, GLY409D, GLY628D, GLY632D, GLY633D, GLY634D, GLY635D, GLY638D, GLY639D, GLY643D, ILE1655, ILE3415, LEU1045, LEU1405, LEU1425, LEU652D, LEU85, LYS185, LYS544D, LYS636D, LYS637D, LYS640D, LYS641D, LYS642D, MET541D, PHE215, PHE542D, PHE646D, PRO275, PRO529D, PRO543D, SER1415, SER1455, SER3445, SER3485, SER3505, SER549D, SER644D, SER645D, THR1485, THR1495, THR3515, THR55, THR648D, THR65, TRP3405, TYR1335, TYR1435, TYR626D, VAL1395, VAL1525, VAL408D, VAL95
• D-7: ASN552D, ASP517, ASP556D, GLY487, LEU554D, LYS507, MET477
• E-F: ARG127E, ARG19F, GLU119E, GLU121F, GLY124E, GLY125E, GLY126E, LEU120E, LEU121E, PHE116E, PHE128E, PRO130E, THR122E, THR123E, THR129E
• E-K: ALA100K, ALA163E, ALA53E, ARG56E, ASN152E, ASP143E, ASP149E, ASP162E, ASP20K, ASP26K, ASP95K, GLU161E, GLU21K, GLU23K, GLU25K, GLY160E, GLY55E, GLY99K, HIS159E, ILE24K, LYS102K, MET54E, MET98K, PHE19K, PRO141E, PRO142E, PRO93K, THR22K, THR78K, TYR155E, VAL103K, VAL156E, VAL96K
• G-H: ALA100H, ALA138H, ALA139H, ALA30H, ALA52H, ALA53H, ALA66H, ALA91H, ARG127H, ARG48H, ARG56H, ARG809G, ARG810G, ARG821G, ASN135H, ASN819G, ASN825G, ASP162H, ASP26H, ASP35H, ASP43H, ASP46H, ASP65H, ASP92H, CYS154H, CYS815G, GLN36H, GLN817G, GLU132H, GLU161H, GLU23H, GLU25H, GLU29H, GLU63H, GLU70H, GLU808G, GLU811G, GLU86H, GLY124H, GLY125H, GLY126H, GLY160H, GLY85H, GLY90H, GLY99H, HIS159H, HIS828G, ILE133H, ILE153H, ILE157H, ILE24H, ILE34H, ILE42H, ILE68H, ILE75H, ILE813G, ILE816G, ILE838G, ILE97H, LEU104H, LEU117H, LEU120H, LEU121H, LEU47H, LEU64H, LEU834G, LEU841G, LEU842G, LEU88H, LYS102H, LYS28H, LYS44H, LYS69H, LYS843G, LYS87H, LYS89H, MET136H, MET54H, MET67H, MET806G, MET824G, MET832G, MET83H, MET98H, PHE101H, PHE116H, PHE128H, PHE140H, PHE19H, PHE27H, PHE31H, PHE51H, PHE80H, PHE814G, PHE823G, PHE835G, PHE836G, PHE84H, PRO830G, PRO840G, PRO93H, SER812G, SER822G, THR122H, THR123H, THR129H, THR158H, THR22H, THR32H, THR50H, TRP137H, TRP829G, TRP831G, TYR155H, TYR818G, VAL103H, VAL144H, VAL156H, VAL33H, VAL59H, VAL820G, VAL826G, VAL96H
• G-I: ALA105I, ALA112I, ALA13I, ALA34I, ALA36I, ALA44I, ALA729G, ALA731G, ALA784G, ALA789G, ALA792G, ALA805G, ARG108I, ARG19I, ARG35I, ARG725G, ARG779G, ARG793G, ARG795G, ARG800G, ARG804G, ASN40I, ASN43I, ASN47I, ASN728G, ASN78I, ASP32I, ASP752G, ASP754G, ASP80I, ASP86I, CYS794G, GLN130I, GLN29I, GLN39I, GLN791G, GLN81I, GLU106I, GLU116I, GLU120I, GLU121I, GLU122I, GLU124I, GLU125I, GLU45I, GLU734G, GLU785G, GLU802G, GLU85I, GLU89I, GLY115I, GLY31I, GLY38I, GLY749G, GLY750G, GLY751G, GLY796G, GLY82I, GLY90I, HIS109I, HIS145I, HIS755G, ILE146I, ILE33I, ILE46I, ILE732G, ILE786G, ILE787G, LEU107I, LEU111I, LEU114I, LEU126I, LEU16I, LEU37I, LEU727G, LEU747G, LEU748G, LEU783G, LEU798G, LEU91I, LYS117I, LYS128I, LYS144I, LYS746G, LYS79I, MET103I, MET118I, MET127I, MET147I, MET799G, MET806G, PHE142I, PHE17I, PHE797G, PHE84I, PHE87I, PHE94I, PRO41I, PRO733G, SER148I, SER730G, THR113I, THR119I, THR42I, THR788G, THR790G, THR83I, TYR724G, TYR803G, VAL110I, VAL123I, VAL143I, VAL149I, VAL726G, VAL753G, VAL801G, VAL88I, VAL93I
• G-6: ALA266, ARG1476, ARG286, ARG3356, ARG654G, ASN410G, ASP16, ASP246, ASP256, ASP36, GLN3546, GLN647G, GLU26, GLU3346, GLU411G, GLU46, GLU537G, GLU539G, GLU629G, GLU631G, GLU655G, GLY1466, GLY632G, GLY633G, GLY635G, GLY639G, ILE3416, LYS544G, LYS636G, LYS637G, LYS640G, LYS641G, LYS642G, PRO529G, SER1416, SER1456, SER3446, SER3486, SER3506, THR3516, TRP3406
• G-8: ASN552G, ASP518, ASP556G, GLY488, LEU554G, LYS508, MET478
• H-I: ARG19I, GLU121I, GLY124H, PHE116H, THR123H
• J-K: ALA100K, ALA138K, ALA139K, ALA163K, ALA30K, ALA52K, ALA53K, ALA66K, ALA91K, ARG127K, ARG48K, ARG56K, ARG809J, ARG810J, ARG821J, ASN135K, ASN819J, ASN825J, ASP162K, ASP26K, ASP35K, ASP43K, ASP46K, ASP92K, CYS154K, CYS815J, GLN817J, GLU132K, GLU161K, GLU23K, GLU25K, GLU29K, GLU63K, GLU70K, GLU808J, GLU811J, GLU86K, GLU94K, GLY124K, GLY125K, GLY126K, GLY160K, GLY55K, GLY85K, GLY90K, GLY99K, HIS159K, HIS828J, ILE133K, ILE153K, ILE157K, ILE34K, ILE42K, ILE68K, ILE75K, ILE813J, ILE816J, ILE838J, ILE97K, LEU104K, LEU117K, LEU120K, LEU121K, LEU47K, LEU64K, LEU834J, LEU841J, LEU842J, LEU88K, LYS102K, LYS44K, LYS843J, LYS87K, LYS89K, MET136K, MET54K, MET67K, MET806J, MET824J, MET832J, MET83K, MET98K, PHE101K, PHE116K, PHE128K, PHE140K, PHE27K, PHE31K, PHE51K, PHE80K, PHE814J, PHE823J, PHE835J, PHE836J, PHE84K, PRO141K, PRO830J, PRO840J, PRO93K, SER812J, SER822J, THR123K, THR129K, THR158K, THR22K, THR50K, TRP137K, TRP829J, TRP831J, TYR155K, TYR818J, VAL103K, VAL144K, VAL156K, VAL33K, VAL59K, VAL820J, VAL826J, VAL96K
• J-L: ALA112L, ALA13L, ALA34L, ALA36L, ALA44L, ALA729J, ALA731J, ALA784J, ALA789J, ALA792J, ALA805J, ARG19L, ARG35L, ARG779J, ARG793J, ARG795J, ARG800J, ARG804J, ARG809J, ARG810J, ASN40L, ASN43L, ASN47L, ASN728J, ASN78L, ASP32L, ASP752J, ASP80L, ASP86L, CYS794J, GLN130L, GLN39L, GLN791J, GLN81L, GLU116L, GLU120L, GLU121L, GLU122L, GLU124L, GLU125L, GLU45L, GLU785J, GLU802J, GLU85L, GLU89L, GLY115L, GLY31L, GLY38L, GLY749J, GLY750J, GLY751J, GLY796J, GLY82L, GLY90L, HIS109L, HIS145L, HIS755J, ILE146L, ILE33L, ILE46L, ILE732J, ILE786J, ILE787J, LEU107L, LEU111L, LEU114L, LEU126L, LEU16L, LEU37L, LEU727J, LEU747J, LEU748J, LEU783J, LEU798J, LEU91L, LYS117L, LYS128L, LYS144L, LYS746J, LYS79L, MET118L, MET127L, MET147L, MET799J, MET806J, PHE142L, PHE17L, PHE797J, PHE84L, PHE87L, PRO41L, SER148L, SER730J, THR113L, THR119L, THR42L, THR788J, THR790J, THR83L, TYR803J, VAL110L, VAL123L, VAL143L, VAL149L, VAL753J, VAL801J, VAL88L, VAL93L
• J-7: ALA267, ARG1477, ARG287, ARG3357, ARG654J, ASN410J, ASP17, ASP247, ASP257, ASP37, GLN3547, GLN647J, GLU27, GLU3347, GLU411J, GLU47, GLU537J, GLU539J, GLU629J, GLU631J, GLU655J, GLY1467, GLY632J, GLY633J, GLY635J, GLY639J, ILE3417, LYS544J, LYS636J, LYS637J, LYS640J, LYS641J, LYS642J, PRO529J, SER1417, SER1457, SER3447, SER3487, SER3507, THR3517, TRP3407
• J-V: ASN552J, ASP51V, ASP556J, GLY48V, LEU554J, LYS50V, MET47V
• K-L: ARG19L, GLU121L, GLY124K, PHE116K, THR122K, THR123K
• 0-1: ALA1740, ARG1770, ARG1961, ARG2561, ARG391, ARG621, ASN1110, ASP1790, ASP1841, ASP1871, ASP2860, CYS2850, GLU1951, GLU2700, GLU2701, GLY1971, GLY2680, GLY2681, GLY631, HIS1730, HIS401, ILE2671, ILE2870, ILE641, ILE750, LEU1100, LEU651, LYS1130, LYS1911, LYS2840, MET2690, MET2691, PHE2661, PRO1120, PRO1720, SER1991, SER2650, SER2651, THR1941, THR2031, TYR1981, VAL2011
• 0-2: ALA2042, ALA3210, ARG1470, ARG2062, ARG2900, ARG3720, ARG392, ARG622, ASP2442, ASP2860, ASP2880, CYS2850, GLN2462, GLN412, GLN592, GLU1670, GLU2052, GLU2072, GLU2412, GLY1460, GLY1680, GLY2452, GLY422, GLY462, GLY632, HIS402, ILE2082, ILE2482, ILE2820, ILE2870, ILE2890, ILE3270, ILE642, LEU1710, LEU2422, LYS2840, LYS2910, LYS3260, LYS612, MET2830, MET3250, MET3550, MET442, PHE2002, PRO2432, PRO3220, SER1992, SER3230, SER602, THR1480, THR1490, THR2022, THR2032, THR3240, THR3510, TYR1430, TYR1660, TYR1690, TYR2402, TYR2940, VAL2012, VAL2472, VAL432, VAL452
• 1-2: ALA1741, ARG1771, ARG1962, ARG2562, ARG392, ARG622, ASN1111, ASP1791, ASP1842, ASP1872, ASP2861, CYS2851, GLU1952, GLU2701, GLU2702, GLY1972, GLY2681, GLY2682, GLY632, HIS1731, HIS402, ILE2672, ILE2871, ILE642, ILE751, LEU1101, LEU652, LYS1131, LYS1912, LYS2841, MET2691, MET2692, PHE2662, PRO1121, PRO1721, SER1992, SER2651, SER2652, THR1942, THR2032, TYR1982, VAL2012
• 1-3: ALA2043, ALA3211, ARG1471, ARG2063, ARG2901, ARG3721, ARG393, ARG623, ASP2443, ASP2861, ASP2881, CYS2851, GLN2463, GLN413, GLN593, GLU1671, GLU2053, GLU2073, GLU2413, GLY1461, GLY1681, GLY2453, GLY423, GLY463, GLY633, HIS403, ILE2083, ILE2483, ILE2821, ILE2871, ILE2891, ILE3271, ILE643, LEU1711, LEU2423, LYS2841, LYS2911, LYS3261, LYS613, MET2831, MET3251, MET3551, MET443, PHE2003, PRO2433, PRO3221, SER1993, SER3231, SER603, THR1481, THR1491, THR2023, THR2033, THR3241, THR3511, TYR1431, TYR1661, TYR1691, TYR2403, TYR2941, VAL2013, VAL2473, VAL433, VAL453
• 2-3: ALA1742, ARG1772, ARG1963, ARG2563, ARG393, ARG623, ASN1112, ASP1792, ASP1843, ASP1873, ASP2862, CYS2852, GLU1953, GLU2702, GLU2703, GLY1973, GLY2682, GLY2683, GLY633, HIS1732, HIS403, ILE2673, ILE2872, ILE643, ILE752, LEU1102, LEU653, LYS1132, LYS1913, LYS2842, MET2692, MET2693, PHE2663, PRO1122, PRO1722, SER1993, SER2652, SER2653, THR1943, THR2033, TYR1983, VAL2013
• 2-4: ALA2044, ALA3212, ARG1472, ARG2064, ARG2902, ARG3722, ARG394, ARG624, ASP2444, ASP2862, ASP2882, CYS2852, GLN2464, GLN414, GLN594, GLU1672, GLU2054, GLU2074, GLU2414, GLY1462, GLY1682, GLY2454, GLY424, GLY464, GLY634, HIS404, ILE2084, ILE2484, ILE2822, ILE2872, ILE2892, ILE3272, ILE644, LEU1712, LEU2424, LYS2842, LYS2912, LYS3262, LYS614, MET2832, MET3252, MET3552, MET444, PHE2004, PRO2434, PRO3222, SER1994, SER3232, SER604, THR1482, THR1492, THR2024, THR2034, THR3242, THR3512, TYR1432, TYR1662, TYR1692, TYR2404, TYR2942, VAL2014, VAL2474, VAL434, VAL454
• 3-4: ALA1743, ARG1773, ARG1964, ARG2564, ARG394, ARG624, ASN1113, ASP1793, ASP1844, ASP1874, ASP2863, CYS2853, GLU1954, GLU2703, GLU2704, GLY1974, GLY2683, GLY2684, GLY634, HIS1733, HIS404, ILE2674, ILE2873, ILE644, ILE753, LEU1103, LEU654, LYS1133, LYS1914, LYS2843, MET2693, MET2694, PHE2664, PRO1123, PRO1723, SER1994, SER2653, SER2654, THR1944, THR2034, TYR1984, VAL2014
• 3-5: ALA2045, ALA3213, ARG1473, ARG2065, ARG2903, ARG3723, ARG395, ARG625, ASP2445, ASP2863, ASP2883, CYS2853, GLN2465, GLN415, GLN595, GLU1673, GLU2055, GLU2075, GLU2415, GLY1463, GLY1683, GLY2455, GLY425, GLY465, GLY635, HIS405, ILE2085, ILE2823, ILE2873, ILE2893, ILE3273, ILE645, LEU1713, LEU2425, LYS2843, LYS2913, LYS3263, LYS615, MET2833, MET3253, MET3553, MET445, PHE2005, PRO2435, PRO3223, SER1995, SER3233, SER605, THR1483, THR1493, THR2025, THR2035, THR3243, THR3513, TYR1433, TYR1663, TYR1693, TYR2405, TYR2943, VAL2015, VAL435, VAL455
• 4-5: ARG1774, ARG1965, ARG395, ARG625, ASN1114, ASP1794, ASP1845, ASP1875, ASP2864, GLU1955, GLU2704, GLU2705, GLY1975, GLY2684, GLY635, HIS1734, HIS405, ILE645, ILE754, LEU1104, LEU655, LYS1134, LYS1915, LYS2844, MET2694, PRO1124, PRO1724, SER1995, SER2654, THR1945, THR2035, TYR1985, VAL2015
• 4-6: ARG2904, ARG626, ASP2446, ASP2864, ASP2884, GLU1674, GLU2056, GLU2076, LYS616, THR2036, THR3244
• 5-6: ASP2865, GLU1956, GLU2706, HIS1735, LYS1135, LYS1916
• 5-7: ARG2905, ARG627, ASP2447, ASP2865, ASP2885, GLU1675, GLU2057, GLU2077, LYS617, THR2037, THR3245
• 6-7: ASP2866, GLU1957, GLU2707, HIS1736, LYS1136, LYS1917
• 6-8: ARG2906, ARG628, ASP2448, ASP2866, ASP2886, GLU1676, GLU2058, GLU2078, LYS618, THR2038, THR3246
• 7-8: ASP2867, GLU1958, GLU2708, HIS1737, LYS1137, LYS1918
• 7-V: ARG2907, ARG62V, ASP244V, ASP2867, ASP2887, GLU1677, GLU205V, GLU207V, LYS61V, THR203V, THR3247
• 8-V: ASP2868, GLU195V, GLU270V, HIS1738, LYS1138, LYS191V
• 8-W: ARG2908, ARG62W, ASP244W, ASP2868, ASP2888, GLU1678, GLU205W, GLU207W, LYS61W, THR203W, THR3248
• V-W: ASP286V, GLU195W, GLU270W, HIS173V, LYS113V, LYS191W
• V-X: ARG290V, ARG62X, ASP244X, ASP286V, ASP288V, GLU167V, GLU205X, GLU207X, LYS61X, THR203X, THR324V
• W-X: ASP286W, GLU195X, GLU270X, HIS173W, LYS113W, LYS191X
• W-Y: ARG290W, ARG62Y, ASP244Y, ASP286W, ASP288W, GLU167W, GLU205Y, GLU207Y, LYS61Y, THR203Y, THR324W
• X-Y: ASP286X, GLU195Y, GLU270Y, HIS173X, LYS113X, LYS191Y
• X-Z: ARG290X, ARG62Z, ASP244Z, ASP286X, ASP288X, GLU167X, GLU205Z, GLU207Z, LYS61Z, THR203Z, THR324X
• Y-Z: ASP286Y, GLU195Z, GLU270Z, HIS173Y, LYS113Y, LYS191Z