1O1D

molecular models of averaged rigor crossbridges from tomograms of insect flight muscle

• Total interactions analyzed: 496
• Total true interactions: 59
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 23
  • Norm. En. per Res.: -0.9063
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-33.5431	1.0258	1379.02	1346.5027	110	300	4	13529	0	19	12
A-C	-29.3579	-49.5627	1044.05	965.1294	105	223	6	12713	3	34	36
A-H	0.0	0.0	-6.0356	-6.0356	8	0	0	335	0	0	0
A-8	-221.1556	50.1778			41
A-V	-38.5738	0.8745			7
B-C	0.0	0.0	-1.708	-1.708	14	0	0	278	0	4	4
B-H	0.0	0.0	18.2504	18.2504	22	5	0	578	0	6	8
B-I	0.0	-3.1348	-0.5691	-3.7039	9	0	0	114	0	6	5
D-E	-27.3415	11.419	1811.81	1795.8874	117	307	9	14516	0	17	13
D-F	-24.3912	-54.6667	1016.64	937.5821	99	248	6	12632	4	33	29
D-K	0.0	0.0	-5.094	-5.094	9	0	0	378	0	1	0
D-9	-220.914	50.15			41
D-W	-38.7709	0.8759			7
E-F	-6.3738	0.0	-14.4701	-20.8439	23	2	0	725	0	7	5
E-K	-24.0562	38.7056	48.7982	63.4476	25	19	0	1144	0	7	19
G-H	-27.8261	5.4119	585.678	563.2637	124	232	8	16251	0	16	11
G-I	-112.3444	-6.0354	821.952	703.5722	118	284	6	14847	8	43	45
G-V	-220.2464	50.0154			41
G-X	-18.2492	15.7602			8
H-I	0.0	0.0	-1.3179	-1.3179	13	0	0	170	0	4	11
J-K	-14.9924	24.8085	577.926	587.742	119	203	6	15197	0	15	12
J-L	-78.2984	-34.8936	1040.38	927.188	92	245	5	12406	3	33	31
J-W	-220.9566	50.1302			41
J-Y	-9.5465	18.5179			6
K-L	0.0	0.0	-2.152	-2.152	12	0	0	223	0	3	8
M-N	-14.6961	19.2408	688.129	692.6737	118	187	5	14033	0	15	12
M-O	-51.3768	-8.7915	572.957	512.7887	114	204	7	13689	4	33	46
M-1	-85.0351	4.2125			12
M-Z	-221.0599	50.116			41
N-O	0.0	0.0	-3.1859	-3.1859	12	0	0	258	0	3	10
P-Q	-14.6619	19.1616	717.616	722.1157	120	185	5	14173	0	15	12
P-R	-89.9658	-23.0676	179.752	66.7186	63	122	1	6064	0	11	13
P-0	-220.8903	50.1059			41
Q-R	0.0	2.6833	-1.6209	1.0624	7	0	0	140	0	0	1
0-1	0.0	21.1756			11
0-2	-8.3444	-44.7934			10
0-Y	-55.9039	48.5119			12
0-Z	0.0	-2.4054			2
1-2	-4.4662	3.6034			8
1-3	0.0	-17.0338			6
1-Z	0.0	-15.9398			9
2-3	-3.5476	2.8744			8
2-4	-7.2561	-13.5458			10
3-4	-2.987	2.6853			8
3-5	0.0	-15.9546			9
4-5	-4.3226	3.3301			8
7-8	0.0	2.3766			6
7-9	-29.0358	-17.3599			11
8-9	0.0	2.3765			6
8-V	-29.0384	-17.3699			11
9-V	0.0	2.3784			6
9-W	-29.0709	-17.3657			11
V-W	0.0	2.3774			6
V-X	-63.0381	9.3212			15
W-X	0.0	-2.1843			2
W-Y	-55.3142	12.4452			11
X-Y	0.0	2.1439			6
X-Z	-46.0073	17.9968			11
Y-Z	0.0	-2.4061			2

Interface residues

• A-B: ALA100B, ALA138B, ALA139B, ALA163B, ALA30B, ALA52B, ALA53B, ALA66B, ALA805A, ALA91B, ARG127B, ARG48B, ARG56B, ARG809A, ARG810A, ARG821A, ASN135B, ASN819A, ASN825A, ASP162B, ASP26B, ASP35B, ASP43B, ASP45B, ASP46B, ASP92B, CYS815A, GLN36B, GLN817A, GLU119B, GLU132B, GLU161B, GLU23B, GLU29B, GLU49B, GLU63B, GLU70B, GLU802A, GLU811A, GLU86B, GLY124B, GLY125B, GLY126B, GLY160B, GLY55B, GLY85B, GLY90B, HIS159B, HIS828A, ILE153B, ILE157B, ILE34B, ILE42B, ILE75B, ILE813A, ILE816A, ILE838A, ILE97B, LEU104B, LEU120B, LEU121B, LEU47B, LEU64B, LEU834A, LEU842A, LEU88B, LYS44B, LYS60B, LYS87B, LYS89B, MET136B, MET54B, MET67B, MET806A, MET824A, MET832A, MET83B, PHE101B, PHE128B, PHE140B, PHE27B, PHE31B, PHE51B, PHE80B, PHE814A, PHE823A, PHE835A, PHE836A, PHE84B, PRO830A, PRO840A, PRO93B, SER812A, SER822A, THR122B, THR123B, THR129B, THR158B, THR32B, THR50B, TRP829A, TRP831A, TYR155B, TYR818A, VAL156B, VAL33B, VAL59B, VAL820A, VAL826A, VAL96B
• A-C: ALA112C, ALA13C, ALA34C, ALA36C, ALA44C, ALA784A, ALA789A, ALA792A, ALA805A, ARG19C, ARG35C, ARG779A, ARG793A, ARG795A, ARG800A, ARG804A, ARG809A, ARG810A, ASN40C, ASN43C, ASN47C, ASP32C, ASP86C, ASP9C, CYS794A, GLN130C, GLN29C, GLN39C, GLN791A, GLN81C, GLU116C, GLU121C, GLU122C, GLU124C, GLU125C, GLU12C, GLU21A, GLU45C, GLU785A, GLU802A, GLU85C, GLU89C, GLY115C, GLY31C, GLY38C, GLY796A, GLY82C, GLY90C, HIS145C, ILE146C, ILE25A, ILE33C, ILE46C, ILE786A, ILE787A, LEU107C, LEU111C, LEU114C, LEU126C, LEU15C, LEU16C, LEU37C, LEU727A, LEU783A, LEU798A, LEU91C, LYS117C, LYS128C, LYS144C, LYS22A, LYS79C, LYS96C, MET103C, MET118C, MET127C, MET147C, MET799A, MET806A, PHE10C, PHE142C, PHE14C, PHE17C, PHE797A, PHE814A, PHE84C, PHE87C, PRO41C, SER148C, THR113C, THR119C, THR42C, THR788A, THR790A, THR83C, TYR803A, VAL110C, VAL123C, VAL143C, VAL149C, VAL30C, VAL726A, VAL801A, VAL807A, VAL88C, VAL93C
• A-H: GLU21H, GLU25H, GLU29H, ILE838A, LEU834A, LEU841A, PRO840A, THR22H
• A-8: ALA268, ARG1478, ARG288, ARG3358, ARG654A, ASN410A, ASP18, ASP248, ASP258, ASP38, GLN3548, GLN647A, GLU28, GLU3348, GLU411A, GLU48, GLU537A, GLU539A, GLU629A, GLU631A, GLU655A, GLY1468, GLY632A, GLY633A, GLY635A, GLY639A, ILE3418, LYS544A, LYS636A, LYS637A, LYS640A, LYS641A, LYS642A, PRO529A, SER1418, SER1458, SER3448, SER3488, SER3508, THR3518, TRP3408
• A-V: ASN552A, ASP51V, ASP556A, GLY48V, LEU554A, LYS50V, MET47V
• B-C: ARG19C, GLU119B, GLU121C, GLY124B, GLY125B, GLY126B, LEU120B, LEU16C, PHE116B, PHE128B, PRO130B, THR122B, THR123B, THR129B
• B-H: ALA163B, ALA52B, ALA53B, ARG56B, ASN58B, ASP162B, ASP20H, ASP95H, GLU21H, GLU25H, GLY55B, ILE24H, LEU57B, LEU81H, MET54B, PHE19H, PHE51B, PHE77H, THR22H, THR50B, THR78H, THR82H
• B-I: ALA141I, ASP132I, GLU131I, GLY129I, HIS145I, LYS114B, LYS134B, LYS144I, SER133I
• D-E: ALA100E, ALA138E, ALA139E, ALA163E, ALA30E, ALA52E, ALA53E, ALA66E, ALA805D, ALA91E, ARG127E, ARG48E, ARG56E, ARG809D, ARG810D, ARG821D, ASN135E, ASN819D, ASN825D, ASP162E, ASP26E, ASP35E, ASP43E, ASP45E, ASP46E, ASP92E, CYS154E, CYS815D, GLN36E, GLN817D, GLU119E, GLU132E, GLU161E, GLU23E, GLU29E, GLU49E, GLU63E, GLU70E, GLU802D, GLU808D, GLU811D, GLU94E, GLY124E, GLY125E, GLY126E, GLY160E, GLY55E, GLY90E, GLY99E, HIS159E, HIS828D, ILE153E, ILE157E, ILE34E, ILE42E, ILE68E, ILE75E, ILE813D, ILE816D, ILE838D, ILE97E, LEU104E, LEU117E, LEU120E, LEU121E, LEU47E, LEU64E, LEU834D, LEU841D, LEU842D, LEU88E, LYS44E, LYS60E, LYS843D, LYS87E, LYS89E, MET136E, MET54E, MET67E, MET806D, MET824D, MET832D, MET83E, MET98E, PHE101E, PHE116E, PHE128E, PHE140E, PHE27E, PHE31E, PHE51E, PHE80E, PHE814D, PHE823D, PHE835D, PHE836D, PHE84E, PRO141E, PRO830D, PRO93E, SER812D, SER822D, THR123E, THR129E, THR158E, THR50E, TRP829D, TRP831D, TYR155E, TYR818D, VAL103E, VAL156E, VAL33E, VAL59E, VAL820D, VAL826D, VAL96E
• D-F: ALA112F, ALA13F, ALA34F, ALA36F, ALA44F, ALA784D, ALA789D, ALA792D, ALA805D, ARG19F, ARG35F, ARG723D, ARG725D, ARG779D, ARG793D, ARG795D, ARG800D, ARG804D, ARG809D, ARG810D, ASN40F, ASN43F, ASN47F, ASP32F, ASP86F, ASP9F, CYS794D, GLN130F, GLN29F, GLN39F, GLN722D, GLN791D, GLN81F, GLU116F, GLU120F, GLU121F, GLU122F, GLU124F, GLU125F, GLU12F, GLU45F, GLU802D, GLU85F, GLU89F, GLY115F, GLY31F, GLY38F, GLY796D, GLY82F, GLY90F, HIS145F, ILE146F, ILE33F, ILE46F, ILE786D, ILE787D, LEU107F, LEU111F, LEU114F, LEU126F, LEU15F, LEU16F, LEU37F, LEU783D, LEU798D, LEU91F, LYS117F, LYS128F, LYS144F, LYS79F, MET118F, MET127F, MET147F, MET799D, MET806D, PHE142F, PHE17F, PHE797D, PHE814D, PHE84F, PHE87F, PRO41F, SER148F, THR113F, THR119F, THR42F, THR788D, THR790D, THR83F, TYR803D, VAL110F, VAL123F, VAL143F, VAL149F, VAL726D, VAL801D, VAL807D, VAL88F, VAL93F
• D-K: GLU21K, GLU25K, ILE838D, LEU841D, LYS28K, PHE77K, PHE835D, PHE836D, PRO840D
• D-9: ALA269, ARG1479, ARG289, ARG3359, ARG654D, ASN410D, ASP19, ASP249, ASP259, ASP39, GLN3549, GLN647D, GLU29, GLU3349, GLU411D, GLU49, GLU537D, GLU539D, GLU629D, GLU631D, GLU655D, GLY1469, GLY632D, GLY633D, GLY635D, GLY639D, ILE3419, LYS544D, LYS636D, LYS637D, LYS640D, LYS641D, LYS642D, PRO529D, SER1419, SER1459, SER3449, SER3489, SER3509, THR3519, TRP3409
• D-W: ASN552D, ASP51W, ASP556D, GLY48W, LEU554D, LYS50W, MET47W
• E-F: ARG127E, ARG19F, ASP18F, GLN29F, GLU119E, GLU121F, GLU125F, GLY124E, GLY125E, GLY126E, LEU120E, LEU121E, LEU16F, LYS128F, PHE116E, PHE128E, PHE17F, PRO106E, PRO130E, THR122E, THR123E, THR129E, THR20F
• E-K: ALA163E, ARG56E, ASP143E, ASP162E, ASP20K, ASP95K, GLU161E, GLU21K, GLU23K, GLU25K, GLY160E, GLY55E, GLY99K, HIS159E, ILE24K, MET54E, PHE19K, PHE77K, PRO141E, PRO142E, THR22K, THR78K, TYR155E, VAL156E, VAL96K
• G-H: ALA100H, ALA138H, ALA139H, ALA30H, ALA52H, ALA53H, ALA66H, ALA71H, ALA91H, ARG127H, ARG48H, ARG56H, ARG809G, ARG810G, ARG821G, ASN135H, ASN819G, ASN825G, ASP162H, ASP26H, ASP35H, ASP43H, ASP46H, ASP65H, ASP92H, CYS154H, CYS815G, GLN36H, GLN817G, GLU132H, GLU161H, GLU23H, GLU25H, GLU29H, GLU49H, GLU63H, GLU70H, GLU802G, GLU808G, GLU811G, GLU86H, GLY124H, GLY125H, GLY126H, GLY160H, GLY85H, GLY90H, GLY99H, HIS159H, HIS828G, ILE153H, ILE157H, ILE24H, ILE34H, ILE42H, ILE68H, ILE75H, ILE813G, ILE816G, ILE838G, ILE97H, LEU104H, LEU117H, LEU120H, LEU121H, LEU47H, LEU64H, LEU834G, LEU841G, LEU842G, LEU88H, LYS102H, LYS28H, LYS44H, LYS69H, LYS843G, LYS87H, LYS89H, MET136H, MET54H, MET67H, MET806G, MET824G, MET832G, MET83H, MET98H, PHE101H, PHE116H, PHE128H, PHE140H, PHE19H, PHE27H, PHE31H, PHE51H, PHE80H, PHE814G, PHE823G, PHE835G, PHE836G, PHE84H, PRO830G, PRO840G, PRO93H, SER812G, SER822G, THR122H, THR123H, THR129H, THR158H, THR22H, THR32H, THR50H, TRP829G, TRP831G, TYR155H, TYR818G, VAL103H, VAL156H, VAL33H, VAL59H, VAL79H, VAL820G, VAL826G, VAL96H
• G-I: ALA105I, ALA112I, ALA13I, ALA34I, ALA36I, ALA44I, ALA729G, ALA731G, ALA784G, ALA789G, ALA792G, ALA805G, ARG108I, ARG19I, ARG35I, ARG779G, ARG793G, ARG795G, ARG800G, ARG804G, ARG809G, ARG810G, ASN40I, ASN43I, ASN47I, ASN728G, ASN78I, ASP32I, ASP752G, ASP86I, ASP95I, CYS794G, GLN130I, GLN29I, GLN39I, GLN791G, GLN81I, GLU106I, GLU116I, GLU120I, GLU121I, GLU122I, GLU124I, GLU125I, GLU45I, GLU734G, GLU785G, GLU802G, GLU808G, GLY115I, GLY31I, GLY38I, GLY749G, GLY750G, GLY751G, GLY796G, GLY82I, GLY90I, HIS109I, HIS145I, HIS755G, ILE146I, ILE33I, ILE46I, ILE732G, ILE786G, ILE787G, LEU111I, LEU114I, LEU126I, LEU16I, LEU37I, LEU727G, LEU747G, LEU748G, LEU798G, LEU91I, LYS117I, LYS128I, LYS144I, LYS48I, LYS742G, LYS746G, LYS79I, LYS96I, MET103I, MET118I, MET127I, MET147I, MET738G, MET799G, MET806G, PHE142I, PHE17I, PHE797G, PHE84I, PHE87I, PHE94I, PRO41I, PRO733G, SER148I, SER28I, SER730G, THR113I, THR119I, THR42I, THR788G, THR790G, THR83I, TYR803G, VAL110I, VAL123I, VAL143I, VAL149I, VAL726G, VAL801G, VAL807G, VAL93I
• G-V: ALA26V, ARG147V, ARG28V, ARG335V, ARG654G, ASN410G, ASP1V, ASP24V, ASP25V, ASP3V, GLN354V, GLN647G, GLU2V, GLU334V, GLU411G, GLU4V, GLU537G, GLU539G, GLU629G, GLU631G, GLU655G, GLY146V, GLY632G, GLY633G, GLY635G, GLY639G, ILE341V, LYS544G, LYS636G, LYS637G, LYS640G, LYS641G, LYS642G, PRO529G, SER141V, SER145V, SER344V, SER348V, SER350V, THR351V, TRP340V
• G-X: ARG95X, ASP556G, GLU557G, GLU57X, GLY46X, GLY48X, LYS50X, LYS567G
• H-I: ARG19I, GLU121I, GLU124I, GLU125I, GLY124H, GLY125H, LEU120H, LYS128I, PHE116H, PRO106H, THR122H, THR123H, VAL103H
• J-K: ALA100K, ALA138K, ALA139K, ALA163K, ALA30K, ALA52K, ALA53K, ALA66K, ALA71K, ALA91K, ARG127K, ARG48K, ARG56K, ARG809J, ARG810J, ARG821J, ASN135K, ASN819J, ASN825J, ASP26K, ASP35K, ASP43K, ASP46K, ASP92K, CYS815J, GLN36K, GLN817J, GLU132K, GLU161K, GLU23K, GLU25K, GLU29K, GLU63K, GLU70K, GLU808J, GLU811J, GLU86K, GLY124K, GLY125K, GLY126K, GLY160K, GLY85K, GLY90K, GLY99K, HIS159K, HIS828J, ILE153K, ILE157K, ILE34K, ILE42K, ILE68K, ILE75K, ILE813J, ILE816J, ILE838J, ILE97K, LEU104K, LEU117K, LEU120K, LEU121K, LEU47K, LEU64K, LEU81K, LEU834J, LEU841J, LEU842J, LEU88K, LYS102K, LYS28K, LYS44K, LYS843J, LYS87K, LYS89K, MET136K, MET54K, MET67K, MET806J, MET824J, MET832J, MET83K, MET98K, PHE101K, PHE116K, PHE128K, PHE140K, PHE19K, PHE27K, PHE31K, PHE51K, PHE80K, PHE814J, PHE823J, PHE835J, PHE836J, PHE84K, PRO830J, PRO840J, PRO93K, SER812J, SER822J, THR122K, THR123K, THR129K, THR158K, THR22K, THR50K, THR82K, TRP829J, TRP831J, TYR155K, TYR818J, VAL103K, VAL156K, VAL33K, VAL59K, VAL79K, VAL820J, VAL826J, VAL96K
• J-L: ALA112L, ALA13L, ALA34L, ALA36L, ALA44L, ALA784J, ALA789J, ALA792J, ALA805J, ARG19L, ARG35L, ARG793J, ARG795J, ARG800J, ARG804J, ARG809J, ARG810J, ASN40L, ASN43L, ASN47L, ASN78L, ASP32L, ASP80L, ASP86L, CYS794J, GLN130L, GLN29L, GLN39L, GLN791J, GLN81L, GLU116L, GLU120L, GLU121L, GLU122L, GLU124L, GLU125L, GLU45L, GLU785J, GLU802J, GLU808J, GLU85L, GLY115L, GLY31L, GLY38L, GLY749J, GLY796J, GLY82L, GLY90L, HIS145L, ILE146L, ILE33L, ILE46L, ILE786J, ILE787J, LEU107L, LEU111L, LEU114L, LEU126L, LEU16L, LEU37L, LEU798J, LEU91L, LYS117L, LYS128L, LYS144L, LYS48L, LYS746J, LYS79L, MET118L, MET127L, MET147L, MET799J, MET806J, PHE142L, PHE17L, PHE797J, PHE84L, PHE87L, PRO41L, SER148L, THR113L, THR119L, THR42L, THR788J, THR790J, THR83L, TYR803J, VAL123L, VAL143L, VAL149L, VAL801J, VAL807J
• J-W: ALA26W, ARG147W, ARG28W, ARG335W, ARG654J, ASN410J, ASP1W, ASP24W, ASP25W, ASP3W, GLN354W, GLN647J, GLU2W, GLU334W, GLU411J, GLU4W, GLU537J, GLU539J, GLU629J, GLU631J, GLU655J, GLY146W, GLY632J, GLY633J, GLY635J, GLY639J, ILE341W, LYS544J, LYS636J, LYS637J, LYS640J, LYS641J, LYS642J, PRO529J, SER141W, SER145W, SER344W, SER348W, SER350W, THR351W, TRP340W
• J-Y: ARG95Y, ASP556J, GLU57Y, GLY48Y, LYS50Y, LYS567J
• K-L: ARG19L, GLU121L, GLU125L, GLY124K, GLY125K, LEU120K, LYS128L, PHE116K, PRO106K, THR122K, THR123K, VAL103K
• M-N: ALA100N, ALA138N, ALA139N, ALA163N, ALA30N, ALA52N, ALA53N, ALA66N, ALA71N, ALA805M, ALA91N, ARG127N, ARG48N, ARG56N, ARG809M, ARG810M, ARG821M, ASN135N, ASN819M, ASN825M, ASP162N, ASP26N, ASP35N, ASP43N, ASP46N, ASP92N, CYS815M, GLN36N, GLN817M, GLU132N, GLU161N, GLU23N, GLU25N, GLU29N, GLU63N, GLU70N, GLU802M, GLU808M, GLU811M, GLU86N, GLY124N, GLY125N, GLY126N, GLY160N, GLY85N, GLY90N, GLY99N, HIS159N, HIS828M, ILE153N, ILE157N, ILE34N, ILE42N, ILE68N, ILE75N, ILE813M, ILE816M, ILE838M, ILE97N, LEU104N, LEU117N, LEU120N, LEU121N, LEU47N, LEU64N, LEU834M, LEU841M, LEU842M, LEU88N, LYS102N, LYS28N, LYS44N, LYS843M, LYS87N, LYS89N, MET136N, MET54N, MET67N, MET806M, MET824M, MET832M, MET83N, PHE101N, PHE116N, PHE128N, PHE140N, PHE19N, PHE27N, PHE31N, PHE51N, PHE80N, PHE814M, PHE823M, PHE835M, PHE836M, PHE84N, PRO830M, PRO840M, PRO93N, SER812M, SER822M, THR123N, THR129N, THR158N, THR50N, TRP137N, TRP829M, TRP831M, TYR155N, TYR818M, VAL103N, VAL156N, VAL33N, VAL59N, VAL79N, VAL820M, VAL826M, VAL96N
• M-O: ALA112O, ALA13O, ALA34O, ALA36O, ALA44O, ALA729M, ALA731M, ALA784M, ALA789M, ALA792M, ALA805M, ARG19O, ARG35O, ARG725M, ARG779M, ARG793M, ARG795M, ARG800M, ARG804M, ARG809M, ARG810M, ARG92O, ASN40O, ASN43O, ASN47O, ASN728M, ASN78O, ASP32O, ASP752M, ASP781M, ASP80O, ASP86O, ASP95O, CYS794M, GLN130O, GLN29O, GLN39O, GLN791M, GLN81O, GLU116O, GLU120O, GLU121O, GLU122O, GLU124O, GLU125O, GLU12O, GLU45O, GLU734M, GLU785M, GLU802M, GLU89O, GLU97O, GLY115O, GLY31O, GLY38O, GLY751M, GLY796M, GLY82O, GLY90O, HIS145O, ILE146O, ILE33O, ILE46O, ILE732M, ILE786M, ILE787M, LEU107O, LEU111O, LEU114O, LEU126O, LEU16O, LEU37O, LEU727M, LEU783M, LEU798M, LEU91O, LYS117O, LYS128O, LYS144O, LYS79O, LYS96O, MET118O, MET127O, MET147O, MET778M, MET799M, MET806M, PHE142O, PHE14O, PHE17O, PHE797M, PHE84O, PHE87O, PHE94O, PRO41O, PRO733M, SER148O, SER730M, THR113O, THR119O, THR42O, THR788M, THR790M, THR83O, TYR803M, VAL110O, VAL123O, VAL143O, VAL149O, VAL726M, VAL801M, VAL807M, VAL88O, VAL93O
• M-1: ASN552M, ASP511, ASP556M, GLN491, GLU539M, GLY461, GLY481, LYS501, MET471, PHE550M, SER549M, VAL451
• M-Z: ALA26Z, ARG147Z, ARG28Z, ARG335Z, ARG654M, ASN410M, ASP1Z, ASP24Z, ASP25Z, ASP3Z, GLN354Z, GLN647M, GLU2Z, GLU334Z, GLU411M, GLU4Z, GLU537M, GLU539M, GLU629M, GLU631M, GLU655M, GLY146Z, GLY632M, GLY633M, GLY635M, GLY639M, ILE341Z, LYS544M, LYS636M, LYS637M, LYS640M, LYS641M, LYS642M, PRO529M, SER141Z, SER145Z, SER344Z, SER348Z, SER350Z, THR351Z, TRP340Z
• N-O: ARG19O, GLU121O, GLU125O, GLY124N, GLY125N, LEU120N, LYS128O, PHE116N, PRO106N, THR122N, THR123N, VAL103N
• P-Q: ALA100Q, ALA138Q, ALA139Q, ALA163Q, ALA30Q, ALA52Q, ALA53Q, ALA66Q, ALA71Q, ALA805P, ALA91Q, ARG127Q, ARG48Q, ARG56Q, ARG809P, ARG810P, ARG821P, ASN135Q, ASN819P, ASN825P, ASP162Q, ASP26Q, ASP35Q, ASP43Q, ASP46Q, ASP92Q, CYS815P, GLN36Q, GLN817P, GLU132Q, GLU161Q, GLU23Q, GLU25Q, GLU29Q, GLU63Q, GLU70Q, GLU802P, GLU808P, GLU811P, GLU86Q, GLY124Q, GLY125Q, GLY126Q, GLY160Q, GLY85Q, GLY90Q, GLY99Q, HIS159Q, HIS828P, ILE133Q, ILE153Q, ILE157Q, ILE34Q, ILE42Q, ILE68Q, ILE75Q, ILE813P, ILE816P, ILE838P, ILE97Q, LEU104Q, LEU117Q, LEU120Q, LEU121Q, LEU47Q, LEU64Q, LEU834P, LEU841P, LEU842P, LEU88Q, LYS102Q, LYS28Q, LYS44Q, LYS843P, LYS87Q, LYS89Q, MET136Q, MET54Q, MET67Q, MET806P, MET824P, MET832P, MET83Q, PHE101Q, PHE116Q, PHE128Q, PHE140Q, PHE19Q, PHE27Q, PHE31Q, PHE51Q, PHE80Q, PHE814P, PHE823P, PHE835P, PHE836P, PHE84Q, PRO830P, PRO840P, PRO93Q, SER812P, SER822P, THR122Q, THR123Q, THR129Q, THR158Q, THR50Q, TRP137Q, TRP829P, TRP831P, TYR155Q, TYR818P, VAL103Q, VAL156Q, VAL33Q, VAL59Q, VAL79Q, VAL820P, VAL826P, VAL96Q
• P-R: ALA13R, ALA34R, ALA36R, ALA44R, ALA784P, ALA789P, ALA792P, ARG19R, ARG35R, ARG793P, ARG795P, ARG800P, ARG810P, ARG92R, ASN40R, ASN43R, ASN47R, ASN728P, ASN78R, ASP32R, ASP752P, ASP781P, ASP80R, CYS794P, GLN29R, GLN39R, GLN791P, GLN81R, GLU116R, GLU122R, GLU125R, GLU12R, GLU45R, GLU734P, GLU785P, GLU802P, GLU85R, GLU89R, GLU97R, GLY31R, GLY38R, GLY796P, ILE33R, ILE46R, ILE786P, ILE787P, LEU114R, LEU16R, LEU37R, LEU798P, LYS79R, LYS96R, MET799P, MET806P, PHE17R, PHE797P, PRO41R, THR42R, THR788P, THR790P, TYR803P, VAL801P, VAL807P
• P-0: ALA260, ARG1470, ARG280, ARG3350, ARG654P, ASN410P, ASP10, ASP240, ASP250, ASP30, GLN3540, GLN647P, GLU20, GLU3340, GLU40, GLU411P, GLU537P, GLU539P, GLU629P, GLU631P, GLU655P, GLY1460, GLY632P, GLY633P, GLY635P, GLY639P, ILE3410, LYS544P, LYS636P, LYS637P, LYS640P, LYS641P, LYS642P, PRO529P, SER1410, SER1450, SER3440, SER3480, SER3500, THR3510, TRP3400
• Q-R: ARG19R, ASP107Q, GLU124R, GLY124Q, GLY125Q, THR122Q, THR123Q
• 0-1: ARG1770, ARG1961, ARG2561, ASP2860, ASP2880, GLU1951, GLU2531, GLU2701, HIS1730, LYS1130, LYS1911
• 0-2: ARG392, ARG622, ASP2860, ASP2880, ASP2920, GLU1670, HIS402, LYS2910, LYS612, VAL432
• 0-Y: ALA2040, ARG290Y, ASP2440, ASP286Y, ASP288Y, ASP292Y, GLU2050, GLU2070, GLU2410, LYS291Y, PRO2430, THR2020
• 0-Z: ARG620, GLU270Z
• 1-2: ARG392, ASP2861, GLU1952, GLU2701, GLU2702, HIS1731, LYS1131, LYS1912
• 1-3: ARG623, ASP2861, ASP2881, GLU1671, GLU2073, LYS613
• 1-Z: ARG290Z, ARG621, ASP2441, ASP286Z, ASP288Z, GLU167Z, GLU2051, GLU2071, LYS611
• 2-3: ARG393, ASP2862, GLU1953, GLU2702, GLU2703, HIS1732, LYS1132, LYS1913
• 2-4: ARG2902, ARG624, ASP2444, ASP2862, ASP2882, GLU1672, GLU2054, GLU2074, LYS614, THR3242
• 3-4: ARG394, ASP2863, GLU1954, GLU2703, GLU2704, HIS1733, LYS1133, LYS1914
• 3-5: ARG2903, ARG625, ASP2445, ASP2863, ASP2883, GLU1673, GLU2055, GLU2075, LYS615
• 4-5: ARG395, ASP2864, GLU1955, GLU2704, GLU2705, HIS1734, LYS1134, LYS1915
• 7-8: ASP2867, GLU1958, GLU2708, HIS1737, LYS1137, LYS1918
• 7-9: ARG2907, ARG629, ASP2449, ASP2867, ASP2887, GLU1677, GLU2059, GLU2079, LYS619, THR2039, THR3247
• 8-9: ASP2868, GLU1959, GLU2709, HIS1738, LYS1138, LYS1919
• 8-V: ARG2908, ARG62V, ASP244V, ASP2868, ASP2888, GLU1678, GLU205V, GLU207V, LYS61V, THR203V, THR3248
• 9-V: ASP2869, GLU195V, GLU270V, HIS1739, LYS1139, LYS191V
• 9-W: ARG2909, ARG62W, ASP244W, ASP2869, ASP2889, GLU1679, GLU205W, GLU207W, LYS61W, THR203W, THR3249
• V-W: ASP286V, GLU195W, GLU270W, HIS173V, LYS113V, LYS191W
• V-X: ALA204X, ARG290V, ASP244X, ASP286V, ASP288V, GLU167V, GLU205X, GLU207X, GLY245X, ILE287V, LYS291V, LYS61X, THR202X, THR203X, THR324V
• W-X: ARG62X, GLU270W
• W-Y: ALA204Y, ARG290W, ASP244Y, ASP286W, ASP288W, GLU205Y, GLU207Y, ILE287W, LYS291W, THR202Y, THR203Y
• X-Y: ASP286X, GLU195Y, GLU270Y, HIS173X, LYS113X, LYS191Y
• X-Z: ALA204Z, ARG290X, ASP244Z, ASP286X, ASP288X, ASP292X, GLU205Z, GLU207Z, ILE287X, LYS291X, THR202Z
• Y-Z: ARG62Z, GLU270Y