1O19

molecular models of averaged rigor crossbridges from tomograms of insect flight muscle

• Total interactions analyzed: 496
• Total true interactions: 62
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 24
  • Norm. En. per Res.: -0.9464
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.1914	2.1518	862.893	833.8533	111	263	5	13149	0	19	13
A-C	-38.6908	-53.2612	713.053	621.101	107	212	6	12853	3	34	38
A-H	0.0	0.0	-5.9225	-5.9225	7	0	0	331	0	0	0
A-8	-221.202	50.1822			41
A-V	-38.6778	0.8735			7
B-C	0.0	0.0	-1.1072	-1.1072	10	0	0	215	0	2	4
B-H	0.0	0.0	72.0809	72.0809	21	6	0	572	0	6	8
B-I	0.0	-2.9378	-0.4525	-3.3903	8	0	0	99	0	6	5
D-E	-37.9208	2.5861	1013.06	977.7253	117	244	7	14285	0	18	12
D-F	-33.4062	-61.0307	859.499	765.0621	103	244	7	12726	4	32	31
D-K	0.0	0.0	-8.6137	-8.6137	12	0	0	500	0	1	0
D-9	-220.9095	50.1243			41
D-W	-38.7126	0.8772			7
E-F	-14.1265	0.0	-8.5875	-22.714	24	9	0	729	0	7	5
E-K	-24.33	38.3725	55.2166	69.2591	25	23	0	1199	0	8	19
G-H	-17.831	8.5162	413.527	404.2122	123	221	8	15994	0	17	11
G-I	-94.2945	-2.8516	1268.84	1171.6939	119	256	7	14700	9	40	44
G-V	-220.1975	50.0042			41
G-X	-18.307	15.7588			8
H-I	0.0	0.0	-0.6417	-0.6417	12	0	0	110	0	3	8
J-K	-12.1128	16.4616	531.751	536.0999	119	199	6	14819	0	15	12
J-L	-59.0286	-8.9105	875.04	807.101	92	261	5	12382	3	32	30
J-W	-221.0083	50.1137			41
J-Y	-17.495	15.7795			8
K-L	0.0	0.0	-1.3211	-1.3211	11	0	0	168	0	3	6
M-N	-7.442	19.0807	560.717	572.3557	122	183	6	14286	0	15	11
M-O	-108.7117	-40.8537	530.706	381.1406	107	181	6	13767	5	41	45
M-T	0.0	0.0	-0.7918	-0.7918	7	0	0	157	0	1	0
M-2	-38.9152	0.8771			7
M-Z	-220.965	50.1052			41
N-O	0.0	0.0	-3.3402	-3.3402	11	0	0	260	0	3	10
N-T	0.0	10.2305	-6.2692	3.9613	17	7	0	375	0	4	11
S-T	-14.3421	23.7534	708.812	718.2233	112	185	4	13645	0	14	12
S-U	-58.5302	40.4241	411.872	393.7659	70	118	1	5777	0	11	12
S-2	-220.9975	50.1089			41
S-4	-80.3865	2.4928			11
T-U	0.0	2.7289	-1.0829	1.646	7	0	0	119	0	0	1
1-2	0.0	-1.092			4
1-3	0.0	-17.3935			6
1-Y	-143.4724	9.3155			16
1-Z	-3.8974	6.0224			9
2-3	0.0	22.3222			10
2-4	-15.9279	-13.5496			7
2-Z	-51.1039	-17.356			12
3-4	0.0	2.376			6
3-5	0.0	-16.5913			6
4-5	-4.2233	5.5317			9
4-6	0.0	-16.5947			6
5-6	0.0	2.3778			6
7-8	0.0	2.3756			6
7-9	-29.0552	-17.3576			11
8-9	0.0	2.3767			6
8-V	-29.08	-17.366			11
9-V	0.0	2.3761			6
9-W	-29.0635	-17.3626			11
V-W	0.0	2.3759			6
V-X	-62.9132	9.3157			15
W-X	0.0	-2.1835			2
W-Y	-62.8821	9.314			15
X-Y	0.0	2.3768			6
X-Z	-46.8099	27.2835			11
Y-Z	0.0	-2.9269			2

Interface residues

• A-B: ALA100B, ALA138B, ALA139B, ALA163B, ALA30B, ALA52B, ALA53B, ALA66B, ALA805A, ALA91B, ARG127B, ARG48B, ARG56B, ARG809A, ARG810A, ARG821A, ASN135B, ASN819A, ASN825A, ASP162B, ASP26B, ASP35B, ASP43B, ASP45B, ASP46B, ASP92B, CYS815A, GLN36B, GLN817A, GLU119B, GLU132B, GLU161B, GLU23B, GLU29B, GLU49B, GLU63B, GLU70B, GLU802A, GLU811A, GLU86B, GLY124B, GLY125B, GLY126B, GLY160B, GLY55B, GLY85B, GLY90B, HIS159B, HIS828A, ILE153B, ILE157B, ILE34B, ILE42B, ILE68B, ILE75B, ILE813A, ILE816A, ILE838A, ILE97B, LEU104B, LEU120B, LEU121B, LEU47B, LEU64B, LEU834A, LEU841A, LEU842A, LEU88B, LYS44B, LYS60B, LYS87B, LYS89B, MET136B, MET54B, MET67B, MET806A, MET824A, MET832A, MET83B, PHE101B, PHE128B, PHE140B, PHE27B, PHE31B, PHE51B, PHE80B, PHE814A, PHE823A, PHE835A, PHE836A, PHE84B, PRO830A, PRO840A, PRO93B, SER812A, SER822A, THR122B, THR123B, THR129B, THR158B, THR50B, TRP829A, TRP831A, TYR155B, TYR818A, VAL156B, VAL33B, VAL59B, VAL820A, VAL826A, VAL96B
• A-C: ALA112C, ALA13C, ALA34C, ALA36C, ALA44C, ALA729A, ALA784A, ALA789A, ALA792A, ALA805A, ARG19C, ARG35C, ARG779A, ARG793A, ARG795A, ARG800A, ARG804A, ARG809A, ARG810A, ASN40C, ASN43C, ASN47C, ASN728A, ASP32C, ASP86C, ASP9C, CYS794A, GLN130C, GLN29C, GLN39C, GLN791A, GLN81C, GLU116C, GLU121C, GLU122C, GLU124C, GLU125C, GLU12C, GLU21A, GLU45C, GLU785A, GLU802A, GLU85C, GLU89C, GLY115C, GLY31C, GLY38C, GLY796A, GLY82C, GLY90C, HIS145C, ILE146C, ILE25A, ILE33C, ILE46C, ILE786A, ILE787A, LEU107C, LEU111C, LEU114C, LEU126C, LEU15C, LEU16C, LEU37C, LEU727A, LEU783A, LEU798A, LEU91C, LYS117C, LYS128C, LYS144C, LYS22A, LYS79C, LYS96C, MET103C, MET118C, MET127C, MET147C, MET799A, MET806A, PHE10C, PHE142C, PHE14C, PHE17C, PHE797A, PHE814A, PHE84C, PHE87C, PRO41C, SER148C, THR113C, THR119C, THR42C, THR788A, THR790A, THR83C, TYR803A, VAL110C, VAL123C, VAL143C, VAL149C, VAL30C, VAL726A, VAL801A, VAL807A, VAL88C, VAL93C
• A-H: GLU21H, GLU25H, ILE838A, LEU834A, LEU841A, PRO840A, THR22H
• A-8: ALA268, ARG1478, ARG288, ARG3358, ARG654A, ASN410A, ASP18, ASP248, ASP258, ASP38, GLN3548, GLN647A, GLU28, GLU3348, GLU411A, GLU48, GLU537A, GLU539A, GLU629A, GLU631A, GLU655A, GLY1468, GLY632A, GLY633A, GLY635A, GLY639A, ILE3418, LYS544A, LYS636A, LYS637A, LYS640A, LYS641A, LYS642A, PRO529A, SER1418, SER1458, SER3448, SER3488, SER3508, THR3518, TRP3408
• A-V: ASN552A, ASP51V, ASP556A, GLY48V, LEU554A, LYS50V, MET47V
• B-C: ARG19C, GLU119B, GLU121C, GLY124B, GLY125B, GLY126B, PRO130B, THR122B, THR123B, THR129B
• B-H: ALA163B, ALA52B, ALA53B, ARG56B, ASN58B, ASP162B, ASP20H, ASP95H, GLU21H, GLU25H, GLY55B, ILE24H, LEU57B, LEU81H, MET54B, PHE19H, PHE51B, THR22H, THR50B, THR78H, THR82H
• B-I: ALA141I, ASP132I, GLY129I, HIS145I, LYS114B, LYS134B, LYS144I, SER133I
• D-E: ALA100E, ALA138E, ALA139E, ALA163E, ALA30E, ALA52E, ALA53E, ALA66E, ALA805D, ALA91E, ARG127E, ARG48E, ARG56E, ARG809D, ARG810D, ARG821D, ASN135E, ASN819D, ASN825D, ASP162E, ASP26E, ASP35E, ASP43E, ASP45E, ASP46E, ASP92E, CYS154E, CYS815D, GLN36E, GLN817D, GLU132E, GLU161E, GLU23E, GLU29E, GLU49E, GLU63E, GLU70E, GLU802D, GLU808D, GLU811D, GLU94E, GLY124E, GLY125E, GLY126E, GLY160E, GLY55E, GLY90E, GLY99E, HIS159E, HIS828D, ILE153E, ILE157E, ILE34E, ILE42E, ILE68E, ILE75E, ILE813D, ILE816D, ILE838D, ILE97E, LEU104E, LEU117E, LEU120E, LEU121E, LEU47E, LEU64E, LEU834D, LEU841D, LEU842D, LEU88E, LYS102E, LYS44E, LYS87E, LYS89E, MET136E, MET54E, MET67E, MET806D, MET824D, MET832D, MET83E, MET98E, PHE101E, PHE116E, PHE128E, PHE140E, PHE27E, PHE31E, PHE51E, PHE80E, PHE814D, PHE823D, PHE835D, PHE836D, PHE84E, PRO141E, PRO830D, PRO840D, PRO93E, SER812D, SER822D, THR123E, THR129E, THR158E, THR50E, TRP137E, TRP829D, TRP831D, TYR155E, TYR818D, VAL103E, VAL156E, VAL33E, VAL59E, VAL820D, VAL826D, VAL96E
• D-F: ALA112F, ALA13F, ALA34F, ALA36F, ALA44F, ALA729D, ALA784D, ALA789D, ALA792D, ALA805D, ARG19F, ARG35F, ARG723D, ARG725D, ARG779D, ARG793D, ARG795D, ARG800D, ARG804D, ARG809D, ARG810D, ASN40F, ASN43F, ASN47F, ASP32F, ASP86F, ASP9F, CYS794D, GLN130F, GLN29F, GLN39F, GLN722D, GLN791D, GLN81F, GLU116F, GLU120F, GLU121F, GLU122F, GLU124F, GLU125F, GLU12F, GLU45F, GLU802D, GLU85F, GLU89F, GLY115F, GLY31F, GLY38F, GLY796D, GLY82F, GLY90F, HIS145F, ILE146F, ILE33F, ILE46F, ILE786D, ILE787D, LEU107F, LEU111F, LEU114F, LEU126F, LEU15F, LEU16F, LEU37F, LEU783D, LEU798D, LEU91F, LYS117F, LYS128F, LYS144F, LYS79F, MET118F, MET127F, MET147F, MET799D, MET806D, PHE142F, PHE17F, PHE737D, PHE797D, PHE814D, PHE84F, PHE87F, PRO41F, SER148F, SER28F, THR113F, THR119F, THR42F, THR788D, THR790D, THR83F, TYR803D, VAL110F, VAL123F, VAL143F, VAL149F, VAL30F, VAL726D, VAL801D, VAL807D, VAL88F, VAL93F
• D-K: GLU21K, GLU25K, ILE24K, ILE838D, LEU841D, LYS28K, MET832D, PHE77K, PHE835D, PHE836D, PRO840D, THR22K
• D-9: ALA269, ARG1479, ARG289, ARG3359, ARG654D, ASN410D, ASP19, ASP249, ASP259, ASP39, GLN3549, GLN647D, GLU29, GLU3349, GLU411D, GLU49, GLU537D, GLU539D, GLU629D, GLU631D, GLU655D, GLY1469, GLY632D, GLY633D, GLY635D, GLY639D, ILE3419, LYS544D, LYS636D, LYS637D, LYS640D, LYS641D, LYS642D, PRO529D, SER1419, SER1459, SER3449, SER3489, SER3509, THR3519, TRP3409
• D-W: ASN552D, ASP51W, ASP556D, GLY48W, LEU554D, LYS50W, MET47W
• E-F: ARG127E, ARG19F, ASP18F, GLN29F, GLU119E, GLU121F, GLU125F, GLY124E, GLY125E, GLY126E, GLY21F, LEU120E, LEU121E, LEU16F, LYS128F, PHE116E, PHE128E, PHE17F, PRO106E, PRO130E, THR122E, THR123E, THR129E, THR20F
• E-K: ALA163E, ARG56E, ASP143E, ASP162E, ASP20K, ASP95K, GLU161E, GLU21K, GLU23K, GLU25K, GLY160E, GLY55E, GLY99K, HIS159E, ILE24K, MET54E, PHE19K, PHE77K, PRO141E, PRO142E, THR22K, THR78K, TYR155E, VAL156E, VAL96K
• G-H: ALA100H, ALA138H, ALA139H, ALA30H, ALA52H, ALA53H, ALA66H, ALA71H, ALA91H, ARG127H, ARG48H, ARG56H, ARG809G, ARG810G, ARG821G, ASN135H, ASN819G, ASN825G, ASP162H, ASP26H, ASP35H, ASP43H, ASP46H, ASP92H, CYS154H, CYS815G, GLN36H, GLN817G, GLU132H, GLU161H, GLU23H, GLU25H, GLU29H, GLU49H, GLU63H, GLU70H, GLU808G, GLU811G, GLU86H, GLY124H, GLY125H, GLY126H, GLY160H, GLY85H, GLY90H, GLY99H, HIS159H, HIS828G, ILE153H, ILE157H, ILE24H, ILE34H, ILE42H, ILE68H, ILE75H, ILE813G, ILE816G, ILE838G, ILE97H, LEU104H, LEU117H, LEU120H, LEU121H, LEU47H, LEU64H, LEU834G, LEU841G, LEU842G, LEU88H, LYS102H, LYS28H, LYS44H, LYS69H, LYS843G, LYS87H, LYS89H, MET136H, MET54H, MET67H, MET806G, MET824G, MET832G, MET83H, MET98H, PHE101H, PHE116H, PHE128H, PHE140H, PHE19H, PHE27H, PHE31H, PHE51H, PHE80H, PHE814G, PHE823G, PHE835G, PHE836G, PHE84H, PRO830G, PRO840G, PRO93H, SER812G, SER822G, THR122H, THR123H, THR129H, THR158H, THR22H, THR32H, THR50H, TRP137H, TRP829G, TRP831G, TYR155H, TYR818G, VAL103H, VAL156H, VAL33H, VAL59H, VAL79H, VAL820G, VAL826G, VAL96H
• G-I: ALA105I, ALA112I, ALA13I, ALA34I, ALA36I, ALA44I, ALA729G, ALA731G, ALA784G, ALA789G, ALA792G, ALA805G, ARG108I, ARG19I, ARG35I, ARG725G, ARG779G, ARG793G, ARG795G, ARG800G, ARG804G, ARG809G, ARG810G, ASN40I, ASN43I, ASN47I, ASN728G, ASN78I, ASP32I, ASP752G, ASP86I, CYS794G, GLN130I, GLN29I, GLN39I, GLN791G, GLN81I, GLU106I, GLU116I, GLU120I, GLU121I, GLU122I, GLU124I, GLU125I, GLU45I, GLU734G, GLU785G, GLU802G, GLU808G, GLY115I, GLY31I, GLY38I, GLY749G, GLY750G, GLY751G, GLY796G, GLY82I, GLY90I, HIS109I, HIS145I, HIS755G, ILE146I, ILE33I, ILE46I, ILE732G, ILE786G, ILE787G, LEU107I, LEU111I, LEU114I, LEU126I, LEU16I, LEU37I, LEU727G, LEU747G, LEU748G, LEU798G, LEU91I, LYS117I, LYS128I, LYS144I, LYS48I, LYS742G, LYS746G, LYS79I, LYS96I, MET103I, MET118I, MET127I, MET147I, MET738G, MET799G, MET806G, PHE142I, PHE17I, PHE797G, PHE84I, PHE87I, PHE94I, PRO41I, PRO733G, SER148I, SER730G, THR113I, THR119I, THR42I, THR788G, THR790G, THR83I, TYR803G, VAL110I, VAL123I, VAL143I, VAL149I, VAL726G, VAL753G, VAL801G, VAL807G, VAL93I
• G-V: ALA26V, ARG147V, ARG28V, ARG335V, ARG654G, ASN410G, ASP1V, ASP24V, ASP25V, ASP3V, GLN354V, GLN647G, GLU2V, GLU334V, GLU411G, GLU4V, GLU537G, GLU539G, GLU629G, GLU631G, GLU655G, GLY146V, GLY632G, GLY633G, GLY635G, GLY639G, ILE341V, LYS544G, LYS636G, LYS637G, LYS640G, LYS641G, LYS642G, PRO529G, SER141V, SER145V, SER344V, SER348V, SER350V, THR351V, TRP340V
• G-X: ARG95X, ASP556G, GLU557G, GLU57X, GLY46X, GLY48X, LYS50X, LYS567G
• H-I: ARG19I, GLU121I, GLU125I, GLY124H, GLY125H, LEU120H, LYS128I, PHE116H, PRO106H, THR122H, THR123H, VAL103H
• J-K: ALA100K, ALA138K, ALA139K, ALA163K, ALA30K, ALA52K, ALA53K, ALA66K, ALA71K, ALA91K, ARG127K, ARG48K, ARG56K, ARG809J, ARG810J, ARG821J, ASN135K, ASN819J, ASN825J, ASP162K, ASP26K, ASP35K, ASP43K, ASP46K, ASP92K, CYS815J, GLN36K, GLN817J, GLU132K, GLU161K, GLU23K, GLU25K, GLU29K, GLU63K, GLU70K, GLU808J, GLU811J, GLU86K, GLY124K, GLY125K, GLY126K, GLY160K, GLY85K, GLY90K, GLY99K, HIS159K, HIS828J, ILE133K, ILE153K, ILE157K, ILE34K, ILE42K, ILE68K, ILE75K, ILE813J, ILE816J, ILE838J, ILE97K, LEU104K, LEU117K, LEU120K, LEU121K, LEU47K, LEU64K, LEU81K, LEU834J, LEU841J, LEU842J, LEU88K, LYS28K, LYS44K, LYS843J, LYS87K, LYS89K, MET136K, MET54K, MET67K, MET806J, MET824J, MET832J, MET83K, PHE101K, PHE116K, PHE128K, PHE140K, PHE19K, PHE27K, PHE31K, PHE51K, PHE80K, PHE814J, PHE823J, PHE835J, PHE836J, PHE84K, PRO830J, PRO840J, PRO93K, SER812J, SER822J, THR122K, THR123K, THR129K, THR158K, THR22K, THR50K, THR82K, TRP829J, TRP831J, TYR155K, TYR818J, VAL103K, VAL156K, VAL33K, VAL59K, VAL79K, VAL820J, VAL826J, VAL96K
• J-L: ALA112L, ALA13L, ALA34L, ALA36L, ALA44L, ALA784J, ALA789J, ALA792J, ALA805J, ARG19L, ARG35L, ARG793J, ARG795J, ARG800J, ARG804J, ARG809J, ARG810J, ASN40L, ASN43L, ASN47L, ASN78L, ASP32L, ASP86L, CYS794J, GLN130L, GLN29L, GLN39L, GLN791J, GLN81L, GLU116L, GLU120L, GLU121L, GLU122L, GLU124L, GLU125L, GLU45L, GLU785J, GLU802J, GLU808J, GLY115L, GLY31L, GLY38L, GLY749J, GLY796J, GLY82L, GLY90L, HIS145L, HIS755J, ILE146L, ILE33L, ILE46L, ILE786J, ILE787J, LEU107L, LEU111L, LEU114L, LEU126L, LEU16L, LEU37L, LEU798J, LEU91L, LYS117L, LYS128L, LYS144L, LYS48L, LYS746J, LYS79L, MET118L, MET127L, MET147L, MET799J, MET806J, PHE142L, PHE17L, PHE797J, PHE84L, PHE87L, PRO41L, SER148L, SER28L, THR113L, THR119L, THR42L, THR788J, THR790J, THR83L, TYR803J, VAL123L, VAL143L, VAL149L, VAL801J, VAL807J
• J-W: ALA26W, ARG147W, ARG28W, ARG335W, ARG654J, ASN410J, ASP1W, ASP24W, ASP25W, ASP3W, GLN354W, GLN647J, GLU2W, GLU334W, GLU411J, GLU4W, GLU537J, GLU539J, GLU629J, GLU631J, GLU655J, GLY146W, GLY632J, GLY633J, GLY635J, GLY639J, ILE341W, LYS544J, LYS636J, LYS637J, LYS640J, LYS641J, LYS642J, PRO529J, SER141W, SER145W, SER344W, SER348W, SER350W, THR351W, TRP340W
• J-Y: ARG95Y, ASP556J, GLU557J, GLU57Y, GLY46Y, GLY48Y, LYS50Y, LYS567J
• K-L: ARG19L, GLU121L, GLU125L, GLY124K, GLY125K, LEU120K, LYS128L, PHE116K, PRO106K, THR122K, THR123K
• M-N: ALA100N, ALA138N, ALA139N, ALA163N, ALA30N, ALA52N, ALA53N, ALA66N, ALA71N, ALA91N, ARG127N, ARG48N, ARG56N, ARG809M, ARG810M, ARG821M, ASN135N, ASN819M, ASN825M, ASP162N, ASP26N, ASP35N, ASP43N, ASP46N, ASP92N, CYS154N, CYS815M, GLN36N, GLN817M, GLU132N, GLU161N, GLU23N, GLU25N, GLU29N, GLU63N, GLU70N, GLU802M, GLU808M, GLU811M, GLU86N, GLY124N, GLY125N, GLY126N, GLY160N, GLY85N, GLY90N, GLY99N, HIS159N, HIS828M, ILE133N, ILE153N, ILE157N, ILE34N, ILE42N, ILE68N, ILE75N, ILE813M, ILE816M, ILE838M, ILE97N, LEU104N, LEU117N, LEU120N, LEU121N, LEU47N, LEU64N, LEU834M, LEU841M, LEU842M, LEU88N, LYS102N, LYS28N, LYS44N, LYS843M, LYS87N, LYS89N, MET136N, MET54N, MET67N, MET806M, MET824M, MET832M, MET83N, MET98N, PHE101N, PHE116N, PHE128N, PHE140N, PHE19N, PHE27N, PHE31N, PHE51N, PHE80N, PHE814M, PHE823M, PHE835M, PHE836M, PHE84N, PRO830M, PRO840M, PRO93N, SER812M, SER822M, THR122N, THR123N, THR129N, THR158N, THR22N, THR50N, TRP137N, TRP829M, TRP831M, TYR155N, TYR818M, VAL103N, VAL156N, VAL33N, VAL59N, VAL79N, VAL820M, VAL826M, VAL96N
• M-O: ALA112O, ALA13O, ALA34O, ALA36O, ALA44O, ALA729M, ALA789M, ALA792M, ARG19O, ARG35O, ARG725M, ARG779M, ARG793M, ARG795M, ARG800M, ARG804M, ARG809M, ARG810M, ARG92O, ASN29M, ASN40O, ASN43O, ASN47O, ASN728M, ASP32O, ASP86O, ASP9O, CYS794M, GLN130O, GLN29O, GLN39O, GLN791M, GLN81O, GLU116O, GLU120O, GLU121O, GLU122O, GLU124O, GLU125O, GLU12O, GLU26M, GLU45O, GLU785M, GLU802M, GLU85O, GLU89O, GLU97O, GLY115O, GLY31O, GLY38O, GLY796M, GLY82O, GLY90O, HIS145O, ILE146O, ILE33O, ILE46O, ILE786M, ILE787M, LEU107O, LEU111O, LEU114O, LEU126O, LEU16O, LEU37O, LEU727M, LEU783M, LEU798M, LEU91O, LYS117O, LYS128O, LYS144O, LYS22M, LYS79O, MET118O, MET127O, MET147O, MET799M, MET806M, PHE142O, PHE14O, PHE17O, PHE797M, PHE84O, PHE87O, PRO31M, PRO41O, PRO733M, SER148O, SER28O, SER730M, THR113O, THR119O, THR42O, THR788M, THR790M, THR83O, TYR803M, VAL110O, VAL123O, VAL143O, VAL149O, VAL726M, VAL801M, VAL807M, VAL88O, VAL93O
• M-T: GLU21T, GLU25T, LEU841M, LYS28T, PHE77T, PHE836M, PRO840M
• M-2: ASN552M, ASP512, ASP556M, GLY482, LEU554M, LYS502, MET472
• M-Z: ALA26Z, ARG147Z, ARG28Z, ARG335Z, ARG654M, ASN410M, ASP1Z, ASP24Z, ASP25Z, ASP3Z, GLN354Z, GLN647M, GLU2Z, GLU334Z, GLU411M, GLU4Z, GLU537M, GLU539M, GLU629M, GLU631M, GLU655M, GLY146Z, GLY632M, GLY633M, GLY635M, GLY639M, ILE341Z, LYS544M, LYS636M, LYS637M, LYS640M, LYS641M, LYS642M, PRO529M, SER141Z, SER145Z, SER344Z, SER348Z, SER350Z, THR351Z, TRP340Z
• N-O: ARG19O, GLU121O, GLU125O, GLY124N, GLY125N, LYS128O, PHE116N, PRO106N, THR122N, THR123N, VAL103N
• N-T: ALA163N, ASP162N, ASP20T, GLU161N, GLU21T, GLU23T, GLU25T, GLY160N, GLY55N, HIS159N, ILE24T, MET54N, PHE19T, THR22T, THR78T, TYR155N, VAL156N
• S-T: ALA100T, ALA138T, ALA139T, ALA163T, ALA30T, ALA52T, ALA53T, ALA66T, ALA71T, ALA91T, ARG127T, ARG48T, ARG56T, ARG809S, ARG821S, ASN135T, ASN819S, ASN825S, ASP162T, ASP26T, ASP35T, ASP43T, ASP46T, ASP92T, CYS815S, GLN817S, GLU132T, GLU161T, GLU23T, GLU29T, GLU63T, GLU70T, GLU802S, GLU808S, GLU811S, GLU86T, GLY124T, GLY125T, GLY126T, GLY160T, GLY85T, GLY90T, GLY99T, HIS159T, HIS828S, ILE133T, ILE153T, ILE157T, ILE34T, ILE42T, ILE68T, ILE75T, ILE813S, ILE816S, ILE838S, ILE97T, LEU104T, LEU117T, LEU120T, LEU121T, LEU47T, LEU64T, LEU834S, LEU841S, LEU842S, LEU88T, LYS102T, LYS44T, LYS843S, LYS87T, LYS89T, MET136T, MET54T, MET67T, MET806S, MET824S, MET832S, MET83T, PHE101T, PHE116T, PHE128T, PHE140T, PHE27T, PHE31T, PHE51T, PHE80T, PHE814S, PHE823S, PHE835S, PHE836S, PHE84T, PRO830S, PRO840S, PRO93T, SER812S, SER822S, THR123T, THR129T, THR158T, THR50T, TRP137T, TRP829S, TRP831S, TYR155T, TYR818S, VAL103T, VAL156T, VAL33T, VAL59T, VAL820S, VAL826S, VAL96T
• S-U: ALA13U, ALA34U, ALA36U, ALA44U, ALA789S, ALA792S, ARG19U, ARG35U, ARG779S, ARG793S, ARG795S, ARG800S, ARG804S, ARG810S, ARG92U, ASN40U, ASN43U, ASN47U, ASN78U, ASP32U, ASP752S, ASP80U, ASP86U, ASP95U, CYS794S, GLN29U, GLN39U, GLN791S, GLN81U, GLU106U, GLU116U, GLU122U, GLU125U, GLU12U, GLU45U, GLU734S, GLU785S, GLU802S, GLU85U, GLU89U, GLY31U, GLY38U, GLY796S, HIS755S, ILE33U, ILE46U, ILE786S, ILE787S, LEU114U, LEU16U, LEU37U, LEU783S, LEU798S, LYS117U, LYS48U, LYS742S, LYS746S, LYS79U, LYS96U, MET799S, MET806S, PHE17U, PHE797S, PRO41U, THR42U, THR788S, THR790S, TYR803S, VAL801S, VAL807S
• S-2: ALA262, ARG1472, ARG282, ARG3352, ARG654S, ASN410S, ASP12, ASP242, ASP252, ASP32, GLN3542, GLN647S, GLU22, GLU3342, GLU411S, GLU42, GLU537S, GLU539S, GLU629S, GLU631S, GLU655S, GLY1462, GLY632S, GLY633S, GLY635S, GLY639S, ILE3412, LYS544S, LYS636S, LYS637S, LYS640S, LYS641S, LYS642S, PRO529S, SER1412, SER1452, SER3442, SER3482, SER3502, THR3512, TRP3402
• S-4: ASN552S, ASP514, ASP556S, GLN414, GLN494, GLY464, GLY484, MET474, SER549S, THR546S, THR548S
• T-U: ARG19U, ASP107T, GLU124U, GLY124T, GLY125T, THR122T, THR123T
• 1-2: ARG622, ASP2861, GLU2701, GLU2702
• 1-3: ARG623, ASP2861, ASP2881, GLU1671, GLU2073, LYS613
• 1-Y: ALA2041, ARG290Y, ASP2441, ASP286Y, ASP288Y, GLN2461, GLU167Y, GLU2051, GLU2071, GLY2451, ILE287Y, LYS291Y, LYS611, THR2021, THR2031, THR324Y
• 1-Z: ARG1961, ARG391, ASP286Z, GLU1951, GLU2701, GLU270Z, HIS173Z, LYS113Z, LYS1911
• 2-3: ARG1963, ARG2563, ASP2862, ASP2882, GLU1953, GLU2533, GLU2703, HIS1732, LYS1132, LYS1913
• 2-4: ARG624, ASP2862, ASP2882, GLU1672, GLU2074, HIS404, VAL434
• 2-Z: ARG290Z, ARG622, ASP2442, ASP286Z, ASP288Z, GLU167Z, GLU2052, GLU2072, GLY2452, LYS612, THR2032, THR324Z
• 3-4: ASP2863, GLU1954, GLU2704, HIS1733, LYS1133, LYS1914
• 3-5: ARG625, ASP2863, ASP2883, GLU1673, GLU2075, LYS615
• 4-5: ARG1965, ARG395, ASP2864, GLU1955, GLU2704, GLU2705, HIS1734, LYS1134, LYS1915
• 4-6: ARG626, ASP2864, ASP2884, GLU1674, GLU2076, LYS616
• 5-6: ASP2865, GLU1956, GLU2706, HIS1735, LYS1135, LYS1916
• 7-8: ASP2867, GLU1958, GLU2708, HIS1737, LYS1137, LYS1918
• 7-9: ARG2907, ARG629, ASP2449, ASP2867, ASP2887, GLU1677, GLU2059, GLU2079, LYS619, THR2039, THR3247
• 8-9: ASP2868, GLU1959, GLU2709, HIS1738, LYS1138, LYS1919
• 8-V: ARG2908, ARG62V, ASP244V, ASP2868, ASP2888, GLU1678, GLU205V, GLU207V, LYS61V, THR203V, THR3248
• 9-V: ASP2869, GLU195V, GLU270V, HIS1739, LYS1139, LYS191V
• 9-W: ARG2909, ARG62W, ASP244W, ASP2869, ASP2889, GLU1679, GLU205W, GLU207W, LYS61W, THR203W, THR3249
• V-W: ASP286V, GLU195W, GLU270W, HIS173V, LYS113V, LYS191W
• V-X: ALA204X, ARG290V, ASP244X, ASP286V, ASP288V, GLU167V, GLU205X, GLU207X, GLY245X, ILE287V, LYS291V, LYS61X, THR202X, THR203X, THR324V
• W-X: ARG62X, GLU270W
• W-Y: ALA204Y, ARG290W, ASP244Y, ASP286W, ASP288W, GLU167W, GLU205Y, GLU207Y, GLY245Y, ILE287W, LYS291W, LYS61Y, THR202Y, THR203Y, THR324W
• X-Y: ASP286X, GLU195Y, GLU270Y, HIS173X, LYS113X, LYS191Y
• X-Z: ALA204Z, ARG290X, ASP244Z, ASP286X, ASP288X, ASP292X, GLU205Z, GLU207Z, GLU241Z, LYS291X, THR202Z
• Y-Z: ARG62Z, GLU270Y