1NQI

crystal structure of lactose synthase, a 1:1 complex between beta1,4- galactosyltransferase and alpha-lactalbumin in the presence of glcnac

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 70
  • Norm. En. per Res.: -3.2619
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-27.2916	-8.8524	-125.924	-162.068	69	5	2	5498	3	26	18
A-C	-5.5225	-1.5953	-39.5387	-46.6565	32	2	0	1506	2	33	23
B-C	-14.6618	-5.0315	-67.9656	-87.6589	50	4	3	3580	0	13	6
B-D	0.0	-8.2111	-5.2457	-13.4568	13	0	0	373	1	8	6
C-D	-29.9665	-60.5851	-137.778	-228.3296	70	2	2	6113	4	26	19

Interface residues

• A-B: ALA106A, ALA326B, ALA364B, ALA40A, ARG334B, ARG346B, ARG349B, ARG359B, ARG362B, ASN323B, ASN356B, ASN43A, ASN45A, ASP278B, ASP319B, ASP320B, ASP361B, ASP37A, ASP44A, CYS111A, CYS28A, GLN117A, GLN288B, GLN358B, GLN54A, GLU113A, GLU2A, GLU354B, GLU49A, GLY281B, GLY316B, GLY35A, HIS32A, HIS365B, ILE363B, LEU115A, LEU284B, LYS105A, LYS108A, LYS114A, LYS279B, LYS5A, MET110A, MET225B, PHE280B, PHE290B, PHE31A, PHE360B, PRO109A, PRO285B, PRO355B, PRO357B, SER112A, SER283B, SER34A, THR33A, THR4A, TRP104A, TRP118A, TRP314B, TYR107A, TYR286B, TYR289B, TYR322B, TYR36A, VAL287B, VAL29A, VAL41A, VAL42A
• A-C: ALA90C, ARG119A, ASN71C, ASP14C, ASP83C, ASP86C, ASP87C, ASP88C, CYS120A, CYS6A, CYS73C, CYS91C, GLN117A, GLU116A, GLU121A, GLU84C, GLY74C, HIS10A, ILE75C, ILE89C, LEU80C, LEU85C, LYS114A, LYS122A, LYS5A, LYS62C, LYS79C, LYS94C, PRO123A, SER76C, THR4A, TRP118A
• B-C: ALA276B, ALA337B, ALA40C, ARG271B, ARG334B, ASN336B, ASP37C, ASP78C, ASP82C, CYS77C, GLN269B, GLN39C, GLU65C, GLU84C, GLY281B, GLY340B, GLY51C, HIS272B, ILE339B, LEU284B, LEU80C, LEU81C, LYS341B, LYS62C, LYS79C, MET330B, PHE267B, PHE280B, PHE282B, PHE66C, PRO285B, PRO335B, PRO67C, SER268B, SER283B, SER331B, SER333B, SER63C, SER64C, SER76C, THR1C, THR38C, THR48C, TYR286B, TYR50C, VAL275B, VAL287B, VAL332B, VAL338B, VAL41C
• B-D: ARG349D, ASN259B, GLU137B, GLY143B, HIS261B, LEU140B, LEU141B, LYS351D, PRO139B, PRO144B, SER138B, SER348D, VAL142B
• C-D: ALA106C, ALA364D, ALA40C, ARG346D, ARG349D, ARG359D, ARG362D, ASN323D, ASN356D, ASN43C, ASN45C, ASP319D, ASP320D, ASP361D, ASP37C, ASP44C, CYS111C, CYS28C, GLN117C, GLN288D, GLN358D, GLN54C, GLU113C, GLU2C, GLU354D, GLU49C, GLY281D, GLY316D, GLY35C, GLY46C, HIS32C, HIS365D, ILE363D, LEU115C, LEU284D, LEU3C, LYS105C, LYS108C, LYS114C, LYS122C, LYS279D, LYS351D, LYS5C, MET110C, MET225D, PHE280D, PHE290D, PHE31C, PHE360D, PRO109C, PRO285D, PRO355D, PRO357D, SER112C, SER283D, SER34C, THR33C, THR4C, TRP104C, TRP118C, TRP314D, TYR107C, TYR286D, TYR289D, TYR322D, TYR36C, VAL287D, VAL29C, VAL41C, VAL42C