1NN8

cryoem structure of poliovirus receptor bound to poliovirus

• Total interactions analyzed: 21
• Total true interactions: 15
• Strongest Interaction:
  • Chains: S-1
  • Int. Res.: 39
  • Norm. En. per Res.: -0.1636
• Hub Node: R(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
R-S	0.0	0.0	6162.4	6162.4	600	2220	0	51524	0	0	0
R-T	0.0	0.0	4331.6	4331.6	595	1823	0	48703	0	0	0
R-1	0.0	0.0	-0.7619	-0.7619	15	0	0	199	0	0	0
R-2	0.0	0.0	-0.0597	-0.0597	5	0	0	30	0	0	0
S-T	0.0	0.0	4846.26	4846.26	600	2452	0	55831	0	0	0
S-1	0.0	0.0	-6.3809	-6.3809	39	0	0	627	0	0	0
S-2	0.0	0.0	-0.1747	-0.1747	10	0	0	73	0	0	0
T-1	0.0	0.0	45.0411	45.0411	36	9	0	639	0	0	0
T-2	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
1-2	0.0	0.0	-13.9124	-13.9124	101	0	0	2088	0	0	0
1-3	0.0	0.0	-18.4541	-18.4541	170	0	0	2895	0	0	0
1-4	0.0	0.0	-8.5357	-8.5357	65	0	0	1214	0	0	0
2-3	0.0	0.0	-7.6353	-7.6353	67	0	0	1247	0	0	0
2-4	0.0	0.0	-3.1057	-3.1057	23	0	0	484	0	0	0
3-4	0.0	0.0	-2.9869	-2.9869	42	0	0	569	0	0	0

Interface residues

• R-S: ALA101R, ALA101S, ALA106R, ALA106S, ALA143R, ALA143S, ALA149R, ALA149S, ALA164R, ALA164S, ALA175R, ALA175S, ALA262R, ALA262S, ALA268R, ALA268S, ALA290R, ALA290S, ALA292R, ALA292S, ALA295R, ALA295S, ALA317R, ALA317S, ALA320R, ALA320S, ALA323R, ALA323S, ALA33R, ALA33S, ALA67R, ALA67S, ALA76R, ALA76S, ALA96R, ALA96S, ALA97R, ALA97S, ARG104R, ARG104S, ARG109R, ARG109S, ARG114R, ARG114S, ARG133R, ARG133S, ARG140R, ARG140S, ARG165R, ARG165S, ARG172R, ARG172S, ARG269R, ARG269S, ARG300R, ARG300S, ARG321R, ARG321S, ARG68R, ARG68S, ARG91R, ARG91S, ARG98R, ARG98S, ASN105R, ASN105S, ASN120R, ASN120S, ASN147R, ASN147S, ASN188R, ASN188S, ASN218R, ASN218S, ASN237R, ASN237S, ASN253R, ASN253S, ASN254R, ASN254S, ASN260R, ASN260S, ASN271R, ASN271S, ASN278R, ASN278S, ASN307R, ASN307S, ASN313R, ASN313S, ASN316R, ASN316S, ASN55R, ASN55S, ASP117R, ASP117S, ASP136R, ASP136S, ASP182R, ASP182S, ASP215R, ASP215S, ASP252R, ASP252S, ASP267R, ASP267S, ASP303R, ASP303S, ASP43R, ASP43S, CYS123R, CYS123S, CYS166R, CYS166S, CYS221R, CYS221S, CYS266R, CYS266S, CYS312R, CYS312S, CYS49R, CYS49S, GLN130R, GLN130S, GLN146R, GLN146S, GLN152R, GLN152S, GLN155R, GLN155S, GLN176R, GLN176S, GLN191R, GLN191S, GLN213R, GLN213S, GLN232R, GLN232S, GLN259R, GLN259S, GLN293R, GLN293S, GLN296R, GLN296S, GLN322R, GLN322S, GLN328R, GLN328S, GLN32R, GLN32S, GLN36R, GLN36S, GLN52R, GLN52S, GLN63R, GLN63S, GLN80R, GLN80S, GLN82R, GLN82S, GLU102R, GLU102S, GLU116R, GLU116S, GLU118R, GLU118S, GLU150R, GLU150S, GLU159R, GLU159S, GLU224R, GLU224S, GLU226R, GLU226S, GLU229R, GLU229S, GLU245R, GLU245S, GLU261R, GLU261S, GLU273R, GLU273S, GLU324R, GLU324S, GLU57R, GLU57S, GLU71R, GLU71S, GLU88R, GLU88S, GLU93R, GLU93S, GLY100R, GLY100S, GLY112R, GLY112S, GLY119R, GLY119S, GLY131R, GLY131S, GLY158R, GLY158S, GLY170R, GLY170S, GLY171R, GLY171S, GLY184R, GLY184S, GLY185R, GLY185S, GLY194R, GLY194S, GLY198R, GLY198S, GLY216R, GLY216S, GLY250R, GLY250S, GLY258R, GLY258S, GLY276R, GLY276S, GLY284R, GLY284S, GLY294R, GLY294S, GLY319R, GLY319S, GLY39R, GLY39S, GLY42R, GLY42S, GLY70R, GLY70S, GLY73R, GLY73S, GLY83R, GLY83S, HIS180R, HIS180S, HIS225R, HIS225S, HIS60R, HIS60S, HIS69R, HIS69S, HIS79R, HIS79S, ILE137R, ILE137S, ILE177R, ILE177S, ILE207R, ILE207S, ILE248R, ILE248S, ILE299R, ILE299S, ILE306R, ILE306S, ILE311R, ILE311S, LEU103R, LEU103S, LEU108R, LEU108S, LEU113R, LEU113S, LEU124R, LEU124S, LEU139R, LEU139S, LEU142R, LEU142S, LEU156R, LEU156S, LEU183R, LEU183S, LEU196R, LEU196S, LEU205R, LEU205S, LEU208R, LEU208S, LEU233R, LEU233S, LEU234R, LEU234S, LEU238R, LEU238S, LEU257R, LEU257S, LEU264R, LEU264S, LEU286R, LEU286S, LEU297R, LEU297S, LEU298R, LEU298S, LEU310R, LEU310S, LEU318R, LEU318S, LEU325R, LEU325S, LEU41R, LEU41S, LEU47R, LEU47S, LEU51R, LEU51S, LEU64R, LEU64S, LEU92R, LEU92S, LEU99R, LEU99S, LYS144R, LYS144S, LYS153R, LYS153S, LYS217R, LYS217S, LYS222R, LYS222S, LYS230R, LYS230S, LYS304R, LYS304S, LYS90R, LYS90S, MET110R, MET110S, MET163R, MET163S, MET186R, MET186S, MET283R, MET283S, MET56R, MET56S, MET75R, MET75S, PHE111R, PHE111S, PHE125R, PHE125S, PHE128R, PHE128S, PHE195R, PHE195S, PHE228R, PHE228S, PHE289R, PHE289S, PHE40R, PHE40S, PHE78R, PHE78S, PHE94R, PHE94S, PRO129R, PRO129S, PRO145R, PRO145S, PRO160R, PRO160S, PRO162R, PRO162S, PRO173R, PRO173S, PRO174R, PRO174S, PRO187R, PRO187S, PRO193R, PRO193S, PRO210R, PRO210S, PRO231R, PRO231S, PRO243R, PRO243S, PRO244R, PRO244S, PRO272R, PRO272S, PRO274R, PRO274S, PRO285R, PRO285S, PRO287R, PRO287S, PRO288R, PRO288S, PRO301R, PRO301S, PRO305R, PRO305S, PRO34R, PRO34S, PRO38R, PRO38S, PRO48R, PRO48S, PRO54R, PRO54S, PRO84R, PRO84S, SER107R, SER107S, SER132R, SER132S, SER134R, SER134S, SER168R, SER168S, SER181R, SER181S, SER190R, SER190S, SER197R, SER197S, SER204R, SER204S, SER211R, SER211S, SER212R, SER212S, SER227R, SER227S, SER247R, SER247S, SER249R, SER249S, SER270R, SER270S, SER280R, SER280S, SER44R, SER44S, SER62R, SER62S, SER72R, SER72S, SER74R, SER74S, SER85R, SER85S, SER87R, SER87S, SER89R, SER89S, THR122R, THR122S, THR127R, THR127S, THR148R, THR148S, THR157R, THR157S, THR169R, THR169S, THR178R, THR178S, THR189R, THR189S, THR199R, THR199S, THR201R, THR201S, THR203R, THR203S, THR220R, THR220S, THR235R, THR235S, THR239R, THR239S, THR263R, THR263S, THR265R, THR265S, THR275R, THR275S, THR281R, THR281S, THR282R, THR282S, THR308R, THR308S, THR309R, THR309S, THR315R, THR315S, THR326R, THR326S, THR35R, THR35S, THR46R, THR46S, THR59R, THR59S, THR65R, THR65S, THR81R, THR81S, TRP138R, TRP138S, TRP179R, TRP179S, TRP206R, TRP206S, TRP255R, TRP255S, TRP279R, TRP279S, TRP66R, TRP66S, TYR121R, TYR121S, TYR241R, TYR241S, TYR242R, TYR242S, TYR251R, TYR251S, TYR256R, TYR256S, TYR277R, TYR277S, TYR50R, TYR50S, TYR86R, TYR86S, VAL115R, VAL115S, VAL126R, VAL126S, VAL135R, VAL135S, VAL141R, VAL141S, VAL151R, VAL151S, VAL154R, VAL154S, VAL161R, VAL161S, VAL167R, VAL167S, VAL192R, VAL192S, VAL200R, VAL200S, VAL202R, VAL202S, VAL209R, VAL209S, VAL214R, VAL214S, VAL219R, VAL219S, VAL223R, VAL223S, VAL236R, VAL236S, VAL240R, VAL240S, VAL246R, VAL246S, VAL291R, VAL291S, VAL302R, VAL302S, VAL30R, VAL30S, VAL314R, VAL314S, VAL31R, VAL31S, VAL327R, VAL327S, VAL329R, VAL329S, VAL37R, VAL37S, VAL45R, VAL45S, VAL53R, VAL53S, VAL58R, VAL58S, VAL61R, VAL61S, VAL77R, VAL77S, VAL95R, VAL95S
• R-T: ALA101R, ALA101T, ALA106R, ALA106T, ALA143R, ALA143T, ALA149R, ALA149T, ALA164R, ALA164T, ALA175R, ALA175T, ALA262R, ALA262T, ALA268R, ALA268T, ALA290R, ALA290T, ALA292R, ALA292T, ALA295R, ALA295T, ALA317R, ALA317T, ALA320R, ALA320T, ALA323R, ALA323T, ALA33R, ALA33T, ALA67R, ALA67T, ALA76R, ALA76T, ALA96R, ALA96T, ALA97R, ALA97T, ARG104R, ARG104T, ARG109R, ARG109T, ARG114R, ARG114T, ARG133R, ARG133T, ARG140R, ARG140T, ARG165R, ARG165T, ARG172R, ARG172T, ARG269R, ARG269T, ARG300R, ARG300T, ARG321R, ARG321T, ARG68R, ARG68T, ARG91R, ARG91T, ARG98R, ARG98T, ASN105R, ASN105T, ASN120R, ASN120T, ASN147R, ASN147T, ASN188R, ASN188T, ASN218R, ASN218T, ASN237R, ASN237T, ASN253R, ASN254R, ASN260R, ASN260T, ASN271R, ASN271T, ASN278R, ASN278T, ASN307R, ASN307T, ASN313R, ASN313T, ASN316R, ASN316T, ASN55R, ASN55T, ASP117R, ASP117T, ASP136R, ASP136T, ASP182R, ASP182T, ASP215R, ASP215T, ASP252R, ASP252T, ASP267R, ASP267T, ASP303R, ASP303T, ASP43R, ASP43T, CYS123R, CYS123T, CYS166R, CYS166T, CYS221R, CYS221T, CYS266R, CYS266T, CYS312R, CYS312T, CYS49R, CYS49T, GLN130R, GLN130T, GLN146R, GLN146T, GLN152R, GLN152T, GLN155R, GLN155T, GLN176R, GLN176T, GLN191R, GLN191T, GLN213R, GLN213T, GLN232R, GLN232T, GLN259R, GLN259T, GLN293R, GLN293T, GLN296R, GLN296T, GLN322R, GLN322T, GLN328R, GLN328T, GLN32R, GLN32T, GLN36R, GLN36T, GLN52R, GLN52T, GLN63R, GLN63T, GLN80R, GLN80T, GLN82R, GLN82T, GLU102R, GLU102T, GLU116R, GLU116T, GLU118R, GLU118T, GLU150R, GLU150T, GLU159R, GLU159T, GLU224R, GLU224T, GLU226R, GLU226T, GLU229R, GLU229T, GLU245R, GLU245T, GLU261R, GLU261T, GLU273R, GLU273T, GLU324R, GLU324T, GLU57R, GLU57T, GLU71R, GLU71T, GLU88R, GLU88T, GLU93R, GLU93T, GLY100R, GLY100T, GLY112R, GLY112T, GLY119R, GLY119T, GLY131R, GLY131T, GLY158R, GLY158T, GLY170R, GLY170T, GLY171R, GLY171T, GLY184R, GLY184T, GLY185R, GLY185T, GLY194R, GLY194T, GLY198R, GLY198T, GLY216R, GLY216T, GLY250R, GLY250T, GLY258R, GLY258T, GLY276R, GLY276T, GLY284R, GLY284T, GLY294R, GLY294T, GLY319R, GLY319T, GLY39R, GLY39T, GLY42R, GLY42T, GLY70R, GLY70T, GLY73R, GLY73T, GLY83R, GLY83T, HIS180R, HIS180T, HIS225R, HIS225T, HIS60R, HIS60T, HIS69R, HIS69T, HIS79R, HIS79T, ILE137R, ILE137T, ILE177R, ILE177T, ILE207R, ILE207T, ILE248R, ILE248T, ILE299R, ILE299T, ILE306R, ILE306T, ILE311R, ILE311T, LEU103R, LEU103T, LEU108R, LEU108T, LEU113R, LEU113T, LEU124R, LEU124T, LEU139R, LEU139T, LEU142R, LEU142T, LEU156R, LEU156T, LEU183R, LEU183T, LEU196R, LEU196T, LEU205R, LEU205T, LEU208R, LEU208T, LEU233R, LEU233T, LEU234R, LEU234T, LEU238R, LEU238T, LEU257R, LEU257T, LEU264R, LEU264T, LEU286T, LEU297R, LEU297T, LEU298R, LEU298T, LEU310R, LEU310T, LEU318R, LEU318T, LEU325R, LEU325T, LEU41R, LEU41T, LEU47R, LEU47T, LEU51R, LEU51T, LEU64R, LEU64T, LEU92R, LEU92T, LEU99R, LEU99T, LYS144R, LYS144T, LYS153R, LYS153T, LYS217R, LYS217T, LYS222R, LYS222T, LYS230R, LYS230T, LYS304R, LYS304T, LYS90R, LYS90T, MET110R, MET110T, MET163R, MET163T, MET186R, MET186T, MET283R, MET283T, MET56R, MET56T, MET75R, MET75T, PHE111R, PHE111T, PHE125R, PHE125T, PHE128R, PHE128T, PHE195R, PHE195T, PHE228R, PHE228T, PHE289R, PHE289T, PHE40R, PHE40T, PHE78R, PHE78T, PHE94R, PHE94T, PRO129R, PRO129T, PRO145R, PRO145T, PRO160R, PRO160T, PRO162R, PRO162T, PRO173R, PRO173T, PRO174R, PRO174T, PRO187R, PRO187T, PRO193R, PRO193T, PRO210R, PRO210T, PRO231R, PRO231T, PRO243R, PRO243T, PRO244R, PRO244T, PRO272R, PRO272T, PRO274R, PRO274T, PRO285R, PRO285T, PRO287R, PRO287T, PRO288R, PRO288T, PRO301R, PRO301T, PRO305R, PRO305T, PRO34R, PRO34T, PRO38R, PRO38T, PRO48R, PRO48T, PRO54R, PRO54T, PRO84R, PRO84T, SER107R, SER107T, SER132R, SER132T, SER134R, SER134T, SER168R, SER168T, SER181R, SER181T, SER190R, SER190T, SER197R, SER197T, SER204R, SER204T, SER211R, SER211T, SER212R, SER212T, SER227R, SER227T, SER247R, SER247T, SER249R, SER249T, SER270R, SER270T, SER280R, SER280T, SER44R, SER44T, SER62R, SER62T, SER72R, SER72T, SER74R, SER74T, SER85R, SER85T, SER87R, SER87T, SER89R, SER89T, THR122R, THR122T, THR127R, THR127T, THR148R, THR148T, THR157R, THR157T, THR169R, THR169T, THR178R, THR178T, THR189R, THR189T, THR199R, THR199T, THR201R, THR201T, THR203R, THR203T, THR220R, THR220T, THR235R, THR235T, THR239R, THR239T, THR263R, THR263T, THR265R, THR265T, THR275R, THR275T, THR281R, THR281T, THR282R, THR282T, THR308R, THR308T, THR309R, THR309T, THR315R, THR315T, THR326R, THR326T, THR35R, THR35T, THR46R, THR46T, THR59R, THR59T, THR65R, THR65T, THR81R, THR81T, TRP138R, TRP138T, TRP179R, TRP179T, TRP206R, TRP206T, TRP255R, TRP255T, TRP279R, TRP279T, TRP66R, TRP66T, TYR121R, TYR121T, TYR241R, TYR241T, TYR242R, TYR242T, TYR251R, TYR251T, TYR256R, TYR277R, TYR277T, TYR50R, TYR50T, TYR86R, TYR86T, VAL115R, VAL115T, VAL126R, VAL126T, VAL135R, VAL135T, VAL141R, VAL141T, VAL151R, VAL151T, VAL154R, VAL154T, VAL161R, VAL161T, VAL167R, VAL167T, VAL192R, VAL192T, VAL200R, VAL200T, VAL202R, VAL202T, VAL209R, VAL209T, VAL214R, VAL214T, VAL219R, VAL219T, VAL223R, VAL223T, VAL236R, VAL236T, VAL240R, VAL240T, VAL246R, VAL246T, VAL291R, VAL291T, VAL302R, VAL302T, VAL30R, VAL30T, VAL314R, VAL314T, VAL31R, VAL31T, VAL327R, VAL327T, VAL329R, VAL37R, VAL37T, VAL45R, VAL45T, VAL53R, VAL53T, VAL58R, VAL58T, VAL61R, VAL61T, VAL77R, VAL77T, VAL95R, VAL95T
• R-1: ALA2231, ASP2261, GLN82R, GLY131R, GLY2251, GLY83R, LEU2241, LEU2281, LYS1091, PRO129R, PRO84R, SER2271, SER85R, TRP1081, VAL1071
• R-2: HIS60R, THR1382, THR1392, THR1402, THR59R
• S-T: ALA101S, ALA101T, ALA106S, ALA106T, ALA143S, ALA143T, ALA149S, ALA149T, ALA164S, ALA164T, ALA175S, ALA175T, ALA262S, ALA262T, ALA268S, ALA268T, ALA290S, ALA290T, ALA292S, ALA292T, ALA295S, ALA295T, ALA317S, ALA317T, ALA320S, ALA320T, ALA323S, ALA323T, ALA33S, ALA33T, ALA67S, ALA67T, ALA76S, ALA76T, ALA96S, ALA96T, ALA97S, ALA97T, ARG104S, ARG104T, ARG109S, ARG109T, ARG114S, ARG114T, ARG133S, ARG133T, ARG140S, ARG140T, ARG165S, ARG165T, ARG172S, ARG172T, ARG269S, ARG269T, ARG300S, ARG300T, ARG321S, ARG321T, ARG68S, ARG68T, ARG91S, ARG91T, ARG98S, ARG98T, ASN105S, ASN105T, ASN120S, ASN120T, ASN147S, ASN147T, ASN188S, ASN188T, ASN218S, ASN218T, ASN237S, ASN237T, ASN253S, ASN253T, ASN254S, ASN254T, ASN260S, ASN260T, ASN271S, ASN271T, ASN278S, ASN278T, ASN307S, ASN307T, ASN313S, ASN313T, ASN316S, ASN316T, ASN55S, ASN55T, ASP117S, ASP117T, ASP136S, ASP136T, ASP182S, ASP182T, ASP215S, ASP215T, ASP252S, ASP252T, ASP267S, ASP267T, ASP303S, ASP303T, ASP43S, ASP43T, CYS123S, CYS123T, CYS166S, CYS166T, CYS221S, CYS221T, CYS266S, CYS266T, CYS312S, CYS312T, CYS49S, CYS49T, GLN130S, GLN130T, GLN146S, GLN146T, GLN152S, GLN152T, GLN155S, GLN155T, GLN176S, GLN176T, GLN191S, GLN191T, GLN213S, GLN213T, GLN232S, GLN232T, GLN259S, GLN259T, GLN293S, GLN293T, GLN296S, GLN296T, GLN322S, GLN322T, GLN328S, GLN328T, GLN32S, GLN32T, GLN36S, GLN36T, GLN52S, GLN52T, GLN63S, GLN63T, GLN80S, GLN80T, GLN82S, GLN82T, GLU102S, GLU102T, GLU116S, GLU116T, GLU118S, GLU118T, GLU150S, GLU150T, GLU159S, GLU159T, GLU224S, GLU224T, GLU226S, GLU226T, GLU229S, GLU229T, GLU245S, GLU245T, GLU261S, GLU261T, GLU273S, GLU273T, GLU324S, GLU324T, GLU57S, GLU57T, GLU71S, GLU71T, GLU88S, GLU88T, GLU93S, GLU93T, GLY100S, GLY100T, GLY112S, GLY112T, GLY119S, GLY119T, GLY131S, GLY131T, GLY158S, GLY158T, GLY170S, GLY170T, GLY171S, GLY171T, GLY184S, GLY184T, GLY185S, GLY185T, GLY194S, GLY194T, GLY198S, GLY198T, GLY216S, GLY216T, GLY250S, GLY250T, GLY258S, GLY258T, GLY276S, GLY276T, GLY284S, GLY284T, GLY294S, GLY294T, GLY319S, GLY319T, GLY39S, GLY39T, GLY42S, GLY42T, GLY70S, GLY70T, GLY73S, GLY73T, GLY83S, GLY83T, HIS180S, HIS180T, HIS225S, HIS225T, HIS60S, HIS60T, HIS69S, HIS69T, HIS79S, HIS79T, ILE137S, ILE137T, ILE177S, ILE177T, ILE207S, ILE207T, ILE248S, ILE248T, ILE299S, ILE299T, ILE306S, ILE306T, ILE311S, ILE311T, LEU103S, LEU103T, LEU108S, LEU108T, LEU113S, LEU113T, LEU124S, LEU124T, LEU139S, LEU139T, LEU142S, LEU142T, LEU156S, LEU156T, LEU183S, LEU183T, LEU196S, LEU196T, LEU205S, LEU205T, LEU208S, LEU208T, LEU233S, LEU233T, LEU234S, LEU234T, LEU238S, LEU238T, LEU257S, LEU257T, LEU264S, LEU264T, LEU286S, LEU286T, LEU297S, LEU297T, LEU298S, LEU298T, LEU310S, LEU310T, LEU318S, LEU318T, LEU325S, LEU325T, LEU41S, LEU41T, LEU47S, LEU47T, LEU51S, LEU51T, LEU64S, LEU64T, LEU92S, LEU92T, LEU99S, LEU99T, LYS144S, LYS144T, LYS153S, LYS153T, LYS217S, LYS217T, LYS222S, LYS222T, LYS230S, LYS230T, LYS304S, LYS304T, LYS90S, LYS90T, MET110S, MET110T, MET163S, MET163T, MET186S, MET186T, MET283S, MET283T, MET56S, MET56T, MET75S, MET75T, PHE111S, PHE111T, PHE125S, PHE125T, PHE128S, PHE128T, PHE195S, PHE195T, PHE228S, PHE228T, PHE289S, PHE289T, PHE40S, PHE40T, PHE78S, PHE78T, PHE94S, PHE94T, PRO129S, PRO129T, PRO145S, PRO145T, PRO160S, PRO160T, PRO162S, PRO162T, PRO173S, PRO173T, PRO174S, PRO174T, PRO187S, PRO187T, PRO193S, PRO193T, PRO210S, PRO210T, PRO231S, PRO231T, PRO243S, PRO243T, PRO244S, PRO244T, PRO272S, PRO272T, PRO274S, PRO274T, PRO285S, PRO285T, PRO287S, PRO287T, PRO288S, PRO288T, PRO301S, PRO301T, PRO305S, PRO305T, PRO34S, PRO34T, PRO38S, PRO38T, PRO48S, PRO48T, PRO54S, PRO54T, PRO84S, PRO84T, SER107S, SER107T, SER132S, SER132T, SER134S, SER134T, SER168S, SER168T, SER181S, SER181T, SER190S, SER190T, SER197S, SER197T, SER204S, SER204T, SER211S, SER211T, SER212S, SER212T, SER227S, SER227T, SER247S, SER247T, SER249S, SER249T, SER270S, SER270T, SER280S, SER280T, SER44S, SER44T, SER62S, SER62T, SER72S, SER72T, SER74S, SER74T, SER85S, SER85T, SER87S, SER87T, SER89S, SER89T, THR122S, THR122T, THR127S, THR127T, THR148S, THR148T, THR157S, THR157T, THR169S, THR169T, THR178S, THR178T, THR189S, THR189T, THR199S, THR199T, THR201S, THR201T, THR203S, THR203T, THR220S, THR220T, THR235S, THR235T, THR239S, THR239T, THR263S, THR263T, THR265S, THR265T, THR275S, THR275T, THR281S, THR281T, THR282S, THR282T, THR308S, THR308T, THR309S, THR309T, THR315S, THR315T, THR326S, THR326T, THR35S, THR35T, THR46S, THR46T, THR59S, THR59T, THR65S, THR65T, THR81S, THR81T, TRP138S, TRP138T, TRP179S, TRP179T, TRP206S, TRP206T, TRP255S, TRP255T, TRP279S, TRP279T, TRP66S, TRP66T, TYR121S, TYR121T, TYR241S, TYR241T, TYR242S, TYR242T, TYR251S, TYR251T, TYR256S, TYR256T, TYR277S, TYR277T, TYR50S, TYR50T, TYR86S, TYR86T, VAL115S, VAL115T, VAL126S, VAL126T, VAL135S, VAL135T, VAL141S, VAL141T, VAL151S, VAL151T, VAL154S, VAL154T, VAL161S, VAL161T, VAL167S, VAL167T, VAL192S, VAL192T, VAL200S, VAL200T, VAL202S, VAL202T, VAL209S, VAL209T, VAL214S, VAL214T, VAL219S, VAL219T, VAL223S, VAL223T, VAL236S, VAL236T, VAL240S, VAL240T, VAL246S, VAL246T, VAL291S, VAL291T, VAL302S, VAL302T, VAL30S, VAL30T, VAL314S, VAL314T, VAL31S, VAL31T, VAL327S, VAL327T, VAL329S, VAL329T, VAL37S, VAL37T, VAL45S, VAL45T, VAL53S, VAL53T, VAL58S, VAL58T, VAL61S, VAL61T, VAL77S, VAL77T, VAL95S, VAL95T
• S-1: ALA1061, ALA2231, ALA2311, ALA2411, ARG133S, ASP1141, ASP2261, GLN130S, GLN82S, GLU1681, GLY131S, GLY2811, GLY83S, HIS60S, ILE1101, ILE2391, LEU2241, LEU2281, LEU2341, LYS1091, LYS1131, PHE128S, PRO129S, PRO2821, PRO84S, SER132S, SER134S, SER2271, SER85S, THR1111, THR127S, THR81S, TRP1081, TYR2291, TYR2801, TYR86S, VAL1071, VAL58S, VAL61S
• S-2: GLN82S, GLU102S, GLY83S, HIS1422, HIS60S, MET1412, THR1382, THR1392, THR1402, THR59S
• T-1: ALA1061, ALA2231, ALA2411, ARG133T, ASN2351, ASP2261, GLN130T, GLN82T, GLU1681, GLY131T, GLY2381, GLY2811, GLY83T, HIS60T, ILE1101, ILE2391, LEU2241, LEU2281, LEU2341, LEU2401, LYS1091, PHE128T, PRO129T, PRO1671, PRO84T, SER132T, SER134T, SER2271, SER85T, THR1111, THR81T, TRP1081, TYR86T, VAL1071, VAL126T, VAL1661
• T-2: HIS60T, THR1402
• 1-2: ALA1332, ALA1482, ALA1902, ALA2041, ALA2221, ALA2311, ALA2761, ALA292, ARG2702, ARG2721, ARG2751, ASN1372, ASN1832, ASN1892, ASN1992, ASN2031, ASN2252, ASN2262, ASN302, ASP2101, ASP2191, ASP2261, ASP2851, ASP2881, CYS1312, CYS2701, GLN1962, GLN2201, GLU1292, GLU481, GLY1342, GLY1842, GLY2111, GLY2282, GLY2301, GLY2811, GLY2831, GLY501, HIS1422, HIS1952, HIS2242, ILE1972, ILE1982, LEU1322, LEU1802, LEU1862, LEU2162, LEU2171, LEU2281, LEU2682, LEU2712, LEU2911, LYS2141, LYS2181, LYS2232, LYS2871, MET1302, MET1412, PHE1612, PHE1912, PHE1932, PHE2081, PHE2121, PRO1282, PRO1942, PRO2161, PRO2692, PRO2711, PRO2731, PRO2741, PRO2821, SER1442, SER2021, SER2061, SER2131, SER2152, SER2271, SER312, THR1261, THR1402, THR1432, THR1852, THR2022, THR2672, THR491, TRP2272, TYR1271, TYR1452, TYR2051, TYR2091, TYR2291, TYR2791, TYR2861, TYR352, VAL1922, VAL2151, VAL2222, VAL2771, VAL2841, VAL322, VAL471
• 1-3: ALA1113, ALA163, ALA1901, ALA2041, ALA243, ALA2761, ALA2781, ALA431, ALA461, ALA511, ALA593, ALA821, ALA851, ARG1201, ARG1291, ARG1931, ARG2233, ARG2671, ARG701, ARG721, ARG831, ARG943, ASN113, ASN2031, ASN2183, ASN291, ASN423, ASN531, ASN633, ASP173, ASP2193, ASP2273, ASP293, ASP2981, ASP503, ASP563, ASP591, CYS1643, CYS2173, CYS233, CYS2701, CYS843, GLN1171, GLN123, GLN1613, GLN2333, GLU1023, GLU1331, GLU2323, GLU393, GLU481, GLU483, GLU741, GLU781, GLY2001, GLY383, GLY841, HIS1533, HIS973, ILE1903, ILE1941, ILE2011, ILE2313, ILE343, ILE363, ILE493, ILE771, ILE823, LEU1193, LEU2243, LEU2253, LEU253, LEU271, LEU2911, LEU2941, LEU2991, LEU441, LEU463, LEU551, LEU573, LEU833, LEU853, LEU873, LYS1153, LYS2971, LYS413, LYS623, MET1663, MET433, MET443, MET993, PHE2203, PHE283, PHE553, PHE801, PRO1413, PRO1693, PRO1811, PRO1911, PRO1971, PRO223, PRO2711, PRO2731, PRO2741, PRO281, PRO2931, PRO323, PRO333, PRO373, PRO421, PRO541, PRO571, PRO813, PRO933, SER1133, SER1623, SER1633, SER1821, SER1913, SER1951, SER2021, SER213, SER2213, SER231, SER2951, SER583, SER711, SER731, SER751, SER761, SER791, SER863, THR1151, THR1173, THR1523, THR153, THR1653, THR1891, THR2283, THR2921, THR2961, THR3001, THR301, THR3011, THR313, THR451, THR521, THR601, TRP1563, TRP1703, TRP2691, TYR1063, TYR1073, TYR133, TYR1893, TYR1981, TYR3021, VAL1161, VAL1543, VAL1673, VAL1683, VAL1961, VAL1991, VAL2223, VAL2681, VAL303, VAL403, VAL471, VAL561, VAL611
• 1-4: ALA201, ALA211, ALA34, ALA374, ALA404, ALA414, ALA431, ALA461, ALA511, ALA654, ALA821, ARG241, ASN531, ASP1311, ASP354, ASP454, GLN44, GLN444, GLN484, GLU1331, GLU401, GLU554, GLU781, GLY501, HIS2651, ILE1941, ILE411, ILE574, LEU441, LEU551, LEU684, LYS2641, LYS391, LYS434, LYS634, MET1321, MET674, PHE464, PHE534, PRO1971, PRO421, PRO541, PRO564, PRO664, SER1951, SER231, SER364, SER384, SER474, SER64, SER71, SER74, SER761, SER791, SER81, SER91, THR101, THR221, THR451, THR491, THR521, THR544, THR644, VAL1961, VAL54
• 2-3: ALA1212, ALA1902, ALA2352, ALA2402, ALA342, ARG2012, ARG372, ARG693, ASN1892, ASN1992, ASN2142, ASN2382, ASN633, ASP1782, ASP2093, ASP503, CYS1213, GLN1192, GLU393, GLU462, GLY1202, GLY1223, GLY1592, GLY1882, GLY362, GLY383, HIS1182, ILE343, ILE363, ILE493, ILE533, LEU1603, LEU1872, LEU2002, LEU2023, LEU2162, LEU2342, LEU463, LYS1162, MET1243, MET1253, MET2083, MET523, MET653, MET993, PHE1172, PHE1912, PHE2392, PRO2053, PRO373, PRO543, SER1233, SER1623, SER2033, SER2152, SER2172, SER2412, THR2022, THR2043, THR513, THR643, THR983, TYR1792, TYR352, TYR683, VAL1922, VAL2132
• 2-4: ALA292, ALA342, ARG122, ASN302, ASN694, ASP112, ASP594, GLY362, ILE574, LEU684, LYS524, LYS584, PHE1932, PHE534, PRO1942, PRO564, SER102, SER312, THR544, TYR352, VAL1922, VAL322, VAL332
• 3-4: ALA374, ALA404, ALA414, ARG344, ASN183, ASN314, ASN394, ASN423, ASP354, ASP494, ASP503, CYS233, GLN1613, GLN203, GLN484, GLU273, GLU393, GLU453, GLU483, GLY383, ILE493, LEU1603, LEU463, LEU684, LYS413, LYS524, MET674, PHE193, PHE464, PHE534, PRO223, PRO263, PRO504, PRO664, SER1623, SER213, SER384, SER474, THR544, TYR324, TYR334, VAL403