1NL0

crystal structure of human factor ix gla domain in complex of an inhibitory antibody, 10c12

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: L-G
  • Int. Res.: 20
  • Norm. En. per Res.: -3.5862
• Hub Node: L(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-38.3933	-27.0488	-421.502	-486.9442	186	17	13	18521	7	29	30
L-G	-18.1161	-18.8008	-34.8064	-71.7232	20	2	0	1284	2	5	0
H-G	-10.3945	2.1323	-136.213	-144.4752	46	9	12	5023	0	1	5

Interface residues

• L-H: ALA100H, ALA125H, ALA128L, ALA131L, ALA136H, ALA137H, ALA168H, ALA174L, ALA175L, ALA208L, ALA43L, ALA49H, ALA60H, ALA89L, ALA90L, ALA93H, ALA95H, ALA98H, ALA99H, ARG100H, ARG105H, ARG38H, ARG94H, ASN129L, ASN170L, ASN31L, ASP101H, ASP139L, ASP144H, ASP217H, ASP50L, ASP61H, ASP85L, CYS135L, CYS140H, CYS216H, CYS88L, CYS92H, GLN127L, GLN168L, GLN171H, GLN1L, GLN37L, GLN38L, GLN39H, GLN3H, GLN6L, GLU124L, GLU125L, GLU161L, GLU212H, GLU46H, GLU6H, GLU95L, GLY101L, GLY104H, GLY106H, GLY139H, GLY159L, GLY162H, GLY41L, GLY42H, GLY44H, GLY99L, HIS164H, HIS35H, HIS39L, ILE137L, ILE48L, ILE50H, LEU100H, LEU118L, LEU124H, LEU126L, LEU133L, LEU136L, LEU138H, LEU141H, LEU170H, LEU175H, LEU178H, LEU179L, LEU181L, LEU45H, LEU46L, LEU4H, LEU95L, LEU97L, LYS117H, LYS130L, LYS143H, LYS167L, LYS172L, LYS209H, LYS210H, LYS214H, LYS42L, LYS43H, LYS45L, LYS53L, LYS64H, MET47L, PHE119L, PHE122H, PHE140L, PHE166H, PHE96L, PHE98L, PRO120L, PRO121L, PRO123H, PRO126H, PRO165L, PRO167H, PRO209L, PRO40L, PRO41H, PRO44L, PRO55L, SER115L, SER120H, SER122L, SER123L, SER138L, SER161H, SER166L, SER169L, SER172H, SER173H, SER176L, SER177H, SER177L, SER179H, SER180H, SER180L, SER215H, SER2L, SER34L, SER56L, SER62H, SER95L, SER96H, THR100L, THR117L, THR132L, THR160H, THR162L, THR163L, THR164L, THR165H, THR183H, THR210L, TRP103H, TRP186L, TRP35L, TRP36H, TRP47H, TRP91L, TYR102H, TYR173L, TYR178L, TYR32L, TYR36L, TYR49L, TYR58H, TYR59H, TYR86L, TYR87L, TYR91H, VAL100H, VAL121H, VAL134L, VAL142H, VAL160L, VAL163H, VAL169H, VAL181H, VAL182H, VAL207L, VAL211H, VAL33L, VAL37H, VAL48H, VAL51L, VAL63H, VAL89H
• L-G: ALA90L, ASN27L, ASN30L, ASN31L, ASP92L, ASP93L, GLU95L, GLY29L, GLY4G, LEU6G, LEU97L, LYS5G, PHE96L, PHE9G, SER27L, SER3G, SER95L, THR27L, TRP91L, TYR32L
• H-G: ALA100H, ALA33H, ALA49H, ALA95H, ALA98H, ALA99H, ARG100H, ARG16G, ARG29G, ARG71H, ASN13G, ASN2G, ASN73H, ASP53H, GLN11G, GLY12G, GLY4G, GLY54H, HIS35H, ILE50H, ILE51H, ILE69H, ILE97H, LEU100H, LEU6G, LYS56H, LYS57H, LYS5G, MET34H, PHE29H, PHE9G, SER30H, SER3G, SER52H, SER55H, SER96H, THR28H, THR31H, TRP47H, TYR32H, TYR52H, TYR58H, TYR59H, VAL100H, VAL10G, VAL31G