1NKQ

crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 166
  • Norm. En. per Res.: -3.5466
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-75.9666	5.2262	-517.993	-588.7334	166	38	7	21346	0	25	40
A-C	-13.7966	-1.2592	-40.3564	-55.4121	21	1	0	1478	1	6	8
A-D	-8.0847	-35.9203	-129.727	-173.732	77	4	0	5601	2	30	31
A-E	0.0	0.0	-1.86	-1.86	11	0	0	107	0	8	2
B-C	0.0	0.0	-0.6209	-0.6209	12	0	0	82	0	9	1
B-E	-9.3605	-2.0294	-43.7695	-55.1593	21	2	0	1582	1	6	8
B-F	-24.7512	-30.8927	-131.906	-187.5498	76	13	0	6153	2	33	32
C-D	-80.0826	10.4341	-481.276	-550.9245	163	21	8	20501	0	25	40
E-F	-82.5494	8.8002	-488.027	-561.7762	168	42	7	20893	0	27	40

Interface residues

• A-B: ALA131A, ALA308B, ALA309B, ALA359B, ALA431B, ALA59A, ALA8A, ALA9A, ARG10A, ARG17A, ARG250A, ARG310B, ARG317B, ARG550B, ASN100A, ASN360B, ASN364B, ASN372B, ASN400B, ASN60A, ASN64A, ASP129A, ASP145A, ASP210A, ASP429B, ASP445B, ASP510B, CYS14A, CYS314B, GLN128A, GLN198A, GLN333B, GLN33A, GLN428B, GLN498B, GLU130A, GLU207A, GLU255A, GLU507B, GLU555B, GLY135A, GLY143A, GLY16A, GLY252A, GLY316B, GLY365B, GLY370B, GLY435B, GLY443B, GLY552B, GLY65A, GLY70A, HIS199A, HIS397B, HIS499B, HIS97A, ILE12A, ILE13A, ILE140A, ILE15A, ILE200A, ILE204A, ILE211A, ILE312B, ILE313B, ILE315B, ILE344B, ILE440B, ILE44A, ILE500B, ILE504B, ILE511B, LEU136A, LEU206A, LEU306B, LEU338B, LEU366B, LEU38A, LEU398B, LEU436B, LEU506B, LEU66A, LEU6A, LEU98A, LYS103A, LYS11A, LYS132A, LYS133A, LYS134A, LYS142A, LYS307B, LYS311B, LYS339B, LYS396B, LYS39A, LYS403B, LYS432B, LYS433B, LYS434B, LYS442B, LYS7A, LYS96A, PHE144A, PHE147A, PHE335B, PHE336B, PHE337B, PHE35A, PHE363B, PHE36A, PHE377B, PHE37A, PHE444B, PHE447B, PHE63A, PHE77A, PRO137A, PRO208A, PRO251A, PRO253A, PRO334B, PRO340B, PRO34A, PRO358B, PRO379B, PRO40A, PRO437B, PRO508B, PRO551B, PRO553B, PRO58A, PRO79A, SER141A, SER201A, SER205A, SER342B, SER343B, SER361B, SER399B, SER42A, SER43A, SER441B, SER501B, SER505B, SER61A, SER99A, THR102A, THR139A, THR146A, THR202A, THR341B, THR362B, THR402B, THR41A, THR439B, THR446B, THR502B, THR62A, TRP138A, TRP438B, TYR254A, TYR305B, TYR554B, TYR5A, VAL101A, VAL401B
• A-C: ARG10C, ARG257A, ARG80A, ASN4C, ASN64C, ASN67C, ASP69C, GLU255A, GLU258A, GLU68C, GLY252A, GLY65C, GLY70C, LEU66C, LYS7C, PHE256A, PHE63C, PRO253A, PRO58C, THR71C, TYR254A
• A-D: ALA308D, ALA309D, ALA59A, ARG181A, ARG228A, ARG250A, ARG257A, ARG310D, ARG456D, ARG80A, ASN177A, ASN244A, ASN249A, ASN304D, ASN60A, ASP227A, ASP369D, ASP411D, ASP510D, CYS247A, GLN179A, GLU222A, GLU246A, GLU248A, GLU255A, GLU368D, GLU457D, GLU507D, GLY178A, GLY226A, GLY415D, GLY509D, GLY74A, GLY81A, HIS230A, HIS397D, ILE393D, ILE413D, ILE453D, LEU223A, LEU306D, LEU48A, LYS224A, LYS307D, LYS311D, LYS396D, LYS458D, LYS463D, LYS83A, PHE245A, PHE256A, PHE459D, PHE77A, PRO225A, PRO251A, PRO508D, PRO58A, PRO75A, SER175A, SER302D, SER395D, SER412D, SER414D, SER455D, SER460D, SER461D, SER61A, THR62A, TYR254A, TYR303D, TYR305D, TYR410D, VAL176A, VAL229A, VAL394D, VAL416D, VAL454D
• A-E: ALA8E, ASN4E, GLN198A, GLU68E, HIS199A, ILE153E, LYS103A, SER114E, SER155E, THR102A, THR202A
• B-C: ALA8C, ASN4C, GLN498B, GLU157C, GLU68C, HIS499B, LYS403B, LYS405B, SER155C, SER2C, THR402B, THR502B
• B-E: ALA8E, ARG10E, ARG380B, ARG557B, ASN4E, ASN64E, ASN67E, ASP69E, GLU555B, GLU558B, GLU68E, GLY552B, GLY65E, GLY70E, LEU66E, LYS7E, PHE556B, PRO553B, PRO58E, THR71E, TYR554B
• B-F: ALA308F, ALA309F, ALA359B, ALA452F, ARG310F, ARG380B, ARG456F, ARG481B, ARG528B, ARG550B, ARG557B, ASN304F, ASN360B, ASN477B, ASN549B, ASP369F, ASP411F, ASP510F, ASP527B, CYS547B, GLN479B, GLU368F, GLU457F, GLU507F, GLU522B, GLU546B, GLU548B, GLU555B, GLY381B, GLY415F, GLY478B, GLY509F, GLY526B, GLY552B, HIS397F, HIS530B, ILE393F, ILE413F, ILE453F, LEU306F, LEU348B, LEU523B, LYS307F, LYS311F, LYS383B, LYS396F, LYS458F, LYS463F, LYS524B, PHE377B, PHE459F, PHE556B, PRO358B, PRO375B, PRO508F, PRO525B, PRO551B, SER302F, SER361B, SER395F, SER412F, SER414F, SER455F, SER460F, SER461F, SER475B, THR362B, TYR303F, TYR305F, TYR410F, TYR462F, TYR554B, VAL394F, VAL454F, VAL476B, VAL529B
• C-D: ALA131C, ALA308D, ALA309D, ALA359D, ALA431D, ALA59C, ALA9C, ARG10C, ARG17C, ARG250C, ARG310D, ARG317D, ARG380D, ARG550D, ASN100C, ASN304D, ASN360D, ASN364D, ASN400D, ASN60C, ASN64C, ASN67C, ASP129C, ASP145C, ASP210C, ASP445D, ASP510D, CYS14C, CYS314D, GLN128C, GLN198C, GLN333D, GLN33C, GLN428D, GLN498D, GLU207C, GLU255C, GLU507D, GLU555D, GLU68C, GLY135C, GLY143C, GLY16C, GLY252C, GLY316D, GLY365D, GLY370D, GLY435D, GLY443D, GLY509D, GLY552D, GLY65C, HIS199C, HIS397D, HIS499D, HIS97C, ILE12C, ILE13C, ILE140C, ILE15C, ILE200C, ILE204C, ILE312D, ILE313D, ILE315D, ILE344D, ILE440D, ILE500D, ILE504D, ILE511D, LEU136C, LEU206C, LEU306D, LEU338D, LEU366D, LEU38C, LEU398D, LEU436D, LEU506D, LEU66C, LEU6C, LEU98C, LYS103C, LYS11C, LYS132C, LYS133C, LYS134C, LYS142C, LYS307D, LYS311D, LYS339D, LYS396D, LYS39C, LYS403D, LYS432D, LYS433D, LYS434D, LYS442D, LYS7C, LYS96C, PHE144C, PHE147C, PHE335D, PHE336D, PHE337D, PHE35C, PHE363D, PHE36C, PHE377D, PHE37C, PHE444D, PHE447D, PHE63C, PHE77C, PRO137C, PRO208C, PRO251C, PRO253C, PRO334D, PRO340D, PRO34C, PRO358D, PRO379D, PRO40C, PRO437D, PRO508D, PRO551D, PRO553D, PRO58C, PRO79C, SER141C, SER201C, SER205C, SER342D, SER343D, SER361D, SER399D, SER42C, SER43C, SER441D, SER501D, SER505D, SER61C, SER99C, THR102C, THR139C, THR146C, THR202C, THR341D, THR362D, THR402D, THR41C, THR439D, THR446D, THR502D, THR62C, TRP138C, TRP438D, TYR254C, TYR305D, TYR554D, VAL101C, VAL401D
• E-F: ALA131E, ALA308F, ALA309F, ALA359F, ALA431F, ALA59E, ALA9E, ARG10E, ARG17E, ARG250E, ARG310F, ARG317F, ARG380F, ARG550F, ASN100E, ASN304F, ASN360F, ASN364F, ASN367F, ASN400F, ASN60E, ASN64E, ASN67E, ASP129E, ASP145E, ASP210E, ASP429F, ASP445F, ASP510F, CYS14E, CYS314F, GLN128E, GLN198E, GLN333F, GLN33E, GLN428F, GLN498F, GLU130E, GLU207E, GLU255E, GLU507F, GLU555F, GLU558F, GLU68E, GLY135E, GLY143E, GLY16E, GLY252E, GLY316F, GLY365F, GLY370F, GLY435F, GLY443F, GLY552F, GLY65E, HIS199E, HIS397F, HIS499F, HIS97E, ILE12E, ILE13E, ILE140E, ILE15E, ILE200E, ILE204E, ILE312F, ILE313F, ILE315F, ILE344F, ILE440F, ILE44E, ILE500F, ILE504F, ILE511F, LEU136E, LEU206E, LEU306F, LEU338F, LEU366F, LEU38E, LEU398F, LEU436F, LEU506F, LEU66E, LEU6E, LEU98E, LYS103E, LYS11E, LYS132E, LYS133E, LYS134E, LYS142E, LYS307F, LYS311F, LYS339F, LYS396F, LYS39E, LYS403F, LYS432F, LYS433F, LYS434F, LYS442F, LYS7E, LYS96E, PHE144E, PHE147E, PHE335F, PHE336F, PHE337F, PHE35E, PHE363F, PHE36E, PHE377F, PHE37E, PHE444F, PHE447F, PHE63E, PHE77E, PRO137E, PRO208E, PRO251E, PRO253E, PRO334F, PRO340F, PRO34E, PRO358F, PRO379F, PRO40E, PRO437F, PRO508F, PRO551F, PRO553F, PRO58E, PRO79E, SER141E, SER201E, SER205E, SER342F, SER343F, SER361F, SER399F, SER42E, SER43E, SER441F, SER501F, SER505F, SER61E, SER99E, THR102E, THR139E, THR146E, THR202E, THR341F, THR362F, THR402F, THR41E, THR439F, THR446F, THR502F, THR62E, TRP138E, TRP438F, TYR254E, TYR303F, TYR305F, TYR554F, VAL101E, VAL401F