1NGM

crystal structure of a yeast brf1-tbp-dna ternary complex

• Total interactions analyzed: 120
• Total true interactions: 7
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 99
  • Norm. En. per Res.: -7.5481
• Hub Node: E(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-107.5763	-141.598	-482.582	-731.7563	137	49	10	20928	7	76	44
E-F	-137.4143	-199.2994	-510.16	-846.8738	141	39	8	21431	11	82	43
E-I	-8.6605	2.5787	-66.008	-72.0898	54	5	1	3153	0	11	13
F-I	-27.3023	0.0	-86.2235	-113.5258	47	7	2	4183	0	8	4
F-J	0.0	0.0	-1.1239	-1.1239	9	0	0	146	0	0	2
I-J	-136.723	-213.252	-397.286	-747.261	99	36	7	15720	15	72	35
M-N	-92.2949	-209.4837	-402.515	-704.2936	98	20	7	15509	16	71	35

Interface residues

• A-B: ALA100A, ALA135A, ALA140A, ALA149A, ALA150A, ALA472B, ALA479B, ALA72A, ALA86A, ALA89A, ALA92A, ARG105A, ARG107A, ARG137A, ARG141A, ARG220A, ARG440B, ARG485B, ARG90A, ARG98A, ASN441B, ASN461B, ASN471B, ASN476B, ASN491B, ASN91A, ASN95A, ASP130A, ASP131A, ASP154A, ASP449B, ASP457B, ASP458B, ASP460B, ASP464B, ASP466B, ASP467B, ASP493B, CYS438B, GLN144A, GLN219A, GLN225A, GLN498B, GLU108A, GLU129A, GLU221A, GLU222A, GLU228A, GLU463B, GLU468B, GLU469B, GLU477B, GLU484B, GLU497B, GLU93A, GLY435B, GLY62A, HIS443B, HIS473B, HIS88A, ILE106A, ILE142A, ILE143A, ILE146A, ILE157A, ILE160A, ILE223A, ILE486B, ILE488B, ILE63A, ILE70A, LEU134A, LEU442B, LEU444B, LEU445B, LEU452B, LEU462B, LEU470B, LEU474B, LEU475B, LEU482B, LEU490B, LEU495B, LEU67A, LEU76A, LEU82A, LEU87A, LYS133A, LYS138A, LYS145A, LYS151A, LYS156A, LYS218A, LYS454B, LYS481B, LYS483B, LYS83A, LYS97A, MET104A, MET121A, PHE152A, PHE155A, PHE227A, PHE494B, PRO109A, PRO232A, PRO439B, PRO446B, PRO459B, PRO65A, PRO96A, SER128A, SER132A, SER136A, SER436B, SER453B, SER456B, SER480B, SER61A, THR153A, THR447B, THR448B, THR450B, THR84A, TRP487B, TYR139A, TYR224A, TYR231A, TYR437B, TYR451B, TYR94A, VAL102A, VAL455B, VAL465B, VAL64A, VAL74A, VAL85A
• E-F: ALA135E, ALA140E, ALA149E, ALA150E, ALA217E, ALA229E, ALA472F, ALA479F, ALA492F, ALA72E, ALA86E, ALA89E, ALA92E, ARG105E, ARG107E, ARG137E, ARG141E, ARG220E, ARG440F, ARG485F, ARG90E, ARG98E, ASN441F, ASN461F, ASN471F, ASN476F, ASN491F, ASN91E, ASN95E, ASP130E, ASP131E, ASP154E, ASP449F, ASP457F, ASP458F, ASP460F, ASP464F, ASP466F, ASP467F, ASP493F, CYS438F, GLN144E, GLN219E, GLN225E, GLN498F, GLU108E, GLU129E, GLU221E, GLU222E, GLU228E, GLU463F, GLU468F, GLU469F, GLU477F, GLU484F, GLU497F, GLU93E, GLY147E, GLY435F, GLY62E, HIS443F, HIS473F, HIS88E, ILE103E, ILE106E, ILE142E, ILE143E, ILE146E, ILE157E, ILE160E, ILE223E, ILE486F, ILE488F, ILE63E, ILE70E, LEU134E, LEU442F, LEU444F, LEU445F, LEU452F, LEU462F, LEU470F, LEU474F, LEU475F, LEU482F, LEU490F, LEU495F, LEU67E, LEU76E, LEU82E, LEU87E, LYS133E, LYS138E, LYS145E, LYS151E, LYS156E, LYS218E, LYS454F, LYS481F, LYS483F, LYS83E, LYS97E, MET104E, MET121E, PHE152E, PHE155E, PHE227E, PHE494F, PRO109E, PRO439F, PRO446F, PRO459F, PRO65E, PRO96E, SER128E, SER132E, SER136E, SER436F, SER453F, SER456F, SER480F, SER61E, THR153E, THR447F, THR448F, THR450F, THR75E, THR84E, TRP487F, TYR139E, TYR224E, TYR231E, TYR437F, TYR451F, TYR94E, VAL102E, VAL455F, VAL465F, VAL64E, VAL74E, VAL85E
• E-I: ARG107E, ARG220E, ARG220I, ARG238I, ASN69E, ASP130E, ASP131E, ASP165E, ASP165I, CYS164E, CYS164I, GLN68E, GLN68I, GLU108E, GLU129E, GLU228I, GLU236I, GLY162E, GLY62E, GLY62I, ILE160E, ILE63E, ILE63I, ILE70E, LEU67E, LEU67I, LYS110E, LYS127E, LYS127I, LYS167E, LYS167I, LYS211E, LYS211I, PHE168I, PHE227I, PRO109E, PRO232I, PRO65E, PRO65I, SER128E, SER128I, SER163E, SER163I, SER235I, SER61E, SER61I, THR66E, THR66I, TYR224E, TYR224I, TYR231I, VAL166I, VAL64E, VAL64I
• F-I: ALA126I, ALA135I, ARG107I, ARG220I, ARG440F, ASN441F, ASP130I, ASP131I, CYS438F, GLN219I, GLN225I, GLN68I, GLU108I, GLU129I, GLU221I, GLU228I, GLY125I, GLY435F, GLY62I, HIS443F, ILE63I, ILE70I, LEU134I, LEU442F, LEU444F, LEU445F, LEU67I, LYS110I, LYS127I, LYS138I, LYS454F, PHE227I, PRO109I, PRO439F, PRO446F, PRO65I, SER128I, SER132I, SER436F, SER61I, THR111I, THR450F, THR66I, TYR224I, TYR437F, TYR451F, VAL64I
• F-J: ASN441F, ASP467J, CYS438F, LEU444F, LYS454J, PRO439F, TYR437F, VAL455J, VAL465J
• I-J: ALA100I, ALA135I, ALA140I, ALA149I, ALA150I, ALA472J, ALA479J, ALA86I, ALA89I, ALA92I, ARG105I, ARG107I, ARG137I, ARG141I, ARG485J, ARG90I, ARG98I, ASN461J, ASN471J, ASN476J, ASN491J, ASN91I, ASN95I, ASP130I, ASP131I, ASP154I, ASP457J, ASP458J, ASP460J, ASP464J, ASP466J, ASP467J, ASP493J, GLN144I, GLN498J, GLU108I, GLU129I, GLU463J, GLU468J, GLU469J, GLU477J, GLU484J, GLU497J, GLU93I, GLY147I, HIS473J, HIS88I, ILE103I, ILE106I, ILE142I, ILE143I, ILE146I, ILE486J, ILE488J, LEU134I, LEU462J, LEU470J, LEU474J, LEU475J, LEU482J, LEU490J, LEU495J, LEU496J, LEU76I, LEU82I, LEU87I, LYS133I, LYS138I, LYS145I, LYS151I, LYS454J, LYS481J, LYS483J, LYS83I, LYS97I, MET104I, MET121I, PHE152I, PHE155I, PHE494J, PRO109I, PRO459J, PRO96I, SER128I, SER132I, SER136I, SER456J, SER480J, THR111I, THR153I, THR84I, TRP487J, TYR139I, TYR94I, VAL102I, VAL455J, VAL465J, VAL74I, VAL85I
• M-N: ALA135M, ALA140M, ALA149M, ALA150M, ALA472N, ALA479N, ALA86M, ALA89M, ALA92M, ARG105M, ARG107M, ARG137M, ARG141M, ARG485N, ARG90M, ARG98M, ASN461N, ASN471N, ASN476N, ASN491N, ASN91M, ASN95M, ASP130M, ASP131M, ASP154M, ASP457N, ASP458N, ASP460N, ASP464N, ASP466N, ASP467N, ASP493N, GLN144M, GLN498N, GLU108M, GLU129M, GLU463N, GLU468N, GLU469N, GLU477N, GLU478N, GLU484N, GLU497N, GLU93M, GLY147M, HIS473N, HIS88M, ILE103M, ILE106M, ILE142M, ILE143M, ILE146M, ILE486N, ILE488N, LEU134M, LEU462N, LEU470N, LEU474N, LEU475N, LEU482N, LEU490N, LEU495N, LEU76M, LEU82M, LEU87M, LYS133M, LYS138M, LYS145M, LYS151M, LYS454N, LYS481N, LYS483N, LYS83M, LYS97M, MET104M, MET121M, PHE152M, PHE155M, PHE494N, PRO109M, PRO459N, PRO96M, SER132M, SER136M, SER456N, SER480N, THR111M, THR153M, THR75M, THR84M, TRP487N, TYR139M, TYR94M, VAL102M, VAL455N, VAL465N, VAL74M, VAL85M