1N8P

crystal structure of cystathionine gamma-lyase from yeast

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 147
  • Norm. En. per Res.: -4.7824
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.8355	21.1704	-403.671	-414.3361	208	32	16	20377	0	19	20
A-C	-24.524	-4.5621	-205.381	-234.4672	73	47	8	9893	2	16	18
A-D	-99.2659	-134.7378	-469.006	-703.0097	147	30	11	19553	16	96	82
B-C	-111.5383	-136.7251	-451.92	-700.1834	149	32	11	19645	16	95	84
B-D	-94.6605	1.9961	-238.176	-330.8404	79	28	8	10506	2	18	17
C-D	-48.3785	21.3277	-437.75	-464.8008	208	46	17	21251	0	19	20

Interface residues

• A-B: ALA114A, ALA114B, ALA116A, ALA116B, ALA201A, ALA233A, ALA233B, ALA236A, ALA236B, ALA243A, ALA243B, ALA316A, ALA319A, ALA323A, ALA323B, ALA332A, ALA332B, ALA346A, ALA41A, ALA41B, ALA81A, ALA81B, ALA84A, ALA84B, ARG108A, ARG108B, ARG327A, ARG51A, ARG51B, ARG57A, ARG57B, ASN115A, ASN115B, ASN206A, ASN206B, ASN232A, ASN232B, ASN42B, ASN54A, ASN54B, ASP210A, ASP210B, ASP242A, ASP242B, GLN231A, GLN231B, GLN37A, GLN37B, GLN53B, GLN88A, GLN88B, GLN92A, GLN92B, GLU317A, GLU333A, GLU333B, GLU339A, GLU343A, GLU48A, GLU48B, GLY104A, GLY105A, GLY105B, GLY118A, GLY118B, GLY207A, GLY235A, GLY235B, GLY337A, GLY79A, GLY79B, GLY93A, GLY93B, HIS107A, HIS107B, HIS117A, HIS117B, HIS208A, HIS208B, ILE234A, ILE234B, ILE237A, ILE237B, ILE29A, ILE29B, ILE44B, ILE86B, LEU213A, LEU213B, LEU230A, LEU230B, LEU245A, LEU245B, LEU31A, LEU31B, LEU331A, LEU331B, LEU335A, LEU335B, LEU341A, LEU341B, LEU342A, LEU87A, LEU87B, LEU90A, LEU90B, LYS112A, LYS112B, LYS203A, LYS203B, LYS321A, LYS36A, LYS36B, MET348A, MET348B, PHE110A, PHE110B, PHE229A, PHE229B, PHE241A, PHE241B, PHE322A, PHE329A, PHE35A, PHE35B, PHE76A, PHE76B, PRO238A, PRO238B, PRO240A, PRO240B, PRO345A, PRO40A, PRO40B, PRO43B, PRO91A, PRO91B, SER200A, SER200B, SER209A, SER209B, SER239A, SER239B, SER30B, SER320A, SER320B, SER324A, SER324B, SER32A, SER32B, SER334A, SER334B, SER340A, SER38B, SER39A, SER39B, SER50A, SER50B, SER52A, SER52B, SER77A, SER77B, SER78A, SER78B, SER80A, SER80B, SER89A, SER89B, SER94A, SER94B, THR106A, THR111A, THR111B, THR202A, THR202B, THR330A, THR330B, THR33A, THR33B, THR349A, THR34A, THR34B, THR82A, THR82B, THR83A, THR83B, THR85A, THR85B, TRP244A, TYR103A, TYR103B, TYR109A, TYR109B, TYR49A, TYR49B, VAL113A, VAL113B, VAL119A, VAL119B, VAL211A, VAL211B, VAL212A, VAL212B, VAL344A, VAL344B, VAL347A, VAL347B, VAL368A
• A-C: ARG248A, ARG248C, ASN54A, ASN54C, ASN56A, ASN56C, ASN59A, ASN59C, ASP20A, ASP20C, GLN37A, GLN37C, GLU17A, GLU17C, GLU27A, GLU27C, GLU48A, GLU48C, GLY23A, GLY23C, GLY45A, GLY45C, HIS18A, HIS18C, HIS22A, HIS22C, ILE26A, ILE26C, ILE29A, ILE29C, ILE44A, ILE44C, LEU31A, LEU31C, LYS36A, LYS36C, PHE241A, PHE241C, PHE35A, PHE35C, PRO240A, PRO28A, PRO28C, PRO43A, PRO43C, PRO55A, PRO55C, SER24A, SER24C, SER30A, SER30C, SER32A, SER32C, SER38A, SER38C, THR1A, THR1C, THR33A, THR33C, THR34A, THR34C, THR46A, THR46C, TRP244A, TRP244C, TYR47A, TYR47C, VAL19A, VAL19C, VAL21A, VAL21C, VAL25A, VAL25C
• A-D: ALA12A, ALA12D, ALA260A, ALA260D, ALA332A, ALA332D, ALA9A, ALA9D, ARG248A, ARG248D, ARG256A, ARG256D, ARG258A, ARG258D, ARG300A, ARG327A, ARG327D, ASN206A, ASN206D, ASP210A, ASP210D, ASP242A, ASP242D, ASP376A, ASP376D, ASP378A, ASP378D, ASP379A, ASP379D, ASP383A, ASP383D, ASP6A, ASP6D, GLN259A, GLN259D, GLN386D, GLN3A, GLN3D, GLU17A, GLU17D, GLU27A, GLU27D, GLU333A, GLU333D, GLU339A, GLU339D, GLU375A, GLU375D, GLU382A, GLU382D, GLU4A, GLU4D, GLY207A, GLY207D, GLY23A, GLY23D, GLY249A, GLY249D, GLY337A, GLY337D, GLY373A, GLY373D, HIS14A, HIS14D, HIS208A, HIS208D, HIS247A, HIS247D, HIS254A, HIS254D, ILE13A, ILE13D, ILE205A, ILE205D, ILE26A, ILE26D, ILE29A, ILE29D, ILE338A, ILE338D, ILE374A, ILE374D, LEU245A, LEU245D, LEU250A, LEU250D, LEU253A, LEU253D, LEU255A, LEU255D, LEU262D, LEU2A, LEU2D, LEU328A, LEU328D, LEU331A, LEU331D, LEU341A, LEU341D, LEU380A, LEU380D, LYS11A, LYS11D, LYS251A, LYS251D, LYS7A, LYS7D, PHE241A, PHE241D, PHE329A, PHE329D, PHE8A, PHE8D, PRO28A, PRO28D, SER209A, SER209D, SER24A, SER24D, SER334A, SER334D, SER340A, SER340D, SER5A, SER5D, THR10A, THR10D, THR1A, THR1D, THR246A, THR246D, THR252A, THR252D, THR326A, THR326D, THR330A, THR330D, THR377A, THR377D, TRP244A, TRP244D, VAL211A, VAL211D, VAL257A, VAL257D, VAL25A, VAL25D
• B-C: ALA12B, ALA12C, ALA243C, ALA260B, ALA260C, ALA332B, ALA332C, ALA9B, ALA9C, ARG248B, ARG248C, ARG256B, ARG256C, ARG258B, ARG258C, ARG300B, ARG300C, ARG327B, ARG327C, ASN206B, ASN206C, ASP210B, ASP210C, ASP242B, ASP242C, ASP376B, ASP376C, ASP378B, ASP378C, ASP379B, ASP379C, ASP383B, ASP383C, ASP6B, ASP6C, GLN259B, GLN259C, GLN386B, GLN3B, GLN3C, GLU17B, GLU17C, GLU27B, GLU27C, GLU333B, GLU333C, GLU339B, GLU339C, GLU375B, GLU375C, GLU382B, GLU4B, GLU4C, GLY207B, GLY207C, GLY23B, GLY23C, GLY249B, GLY249C, GLY337B, GLY337C, GLY373B, GLY373C, HIS14B, HIS14C, HIS208B, HIS208C, HIS247B, HIS247C, HIS254B, HIS254C, ILE13B, ILE13C, ILE205B, ILE205C, ILE26B, ILE26C, ILE29B, ILE29C, ILE338B, ILE338C, ILE374B, ILE374C, LEU245B, LEU245C, LEU250B, LEU250C, LEU253B, LEU253C, LEU255B, LEU255C, LEU262B, LEU2B, LEU2C, LEU328B, LEU328C, LEU331B, LEU331C, LEU341B, LEU341C, LEU380B, LEU380C, LYS11B, LYS11C, LYS251B, LYS251C, LYS7B, LYS7C, PHE241B, PHE241C, PHE329B, PHE329C, PHE8B, PHE8C, PRO28B, PRO28C, SER209B, SER209C, SER24B, SER263C, SER334B, SER334C, SER340B, SER340C, SER5B, SER5C, THR10B, THR10C, THR1B, THR1C, THR246B, THR246C, THR252B, THR252C, THR326B, THR326C, THR330B, THR330C, THR377B, THR377C, TRP244B, TRP244C, TYR185C, VAL211B, VAL211C, VAL257B, VAL257C, VAL25B, VAL25C
• B-D: ARG248B, ARG248D, ASN54B, ASN54D, ASN56B, ASN56D, ASN59B, ASN59D, ASP20B, ASP20D, GLN37B, GLN37D, GLU17B, GLU17D, GLU27B, GLU27D, GLU48B, GLU48D, GLU58B, GLU58D, GLY23B, GLY23D, GLY45B, GLY45D, HIS14B, HIS14D, HIS18B, HIS18D, HIS22B, HIS22D, ILE26B, ILE26D, ILE29B, ILE29D, ILE44B, ILE44D, LEU245B, LEU245D, LEU2D, LEU31B, LEU31D, LYS36B, LYS36D, PHE241B, PHE241D, PHE35B, PHE35D, PRO240B, PRO240D, PRO28B, PRO28D, PRO43B, PRO43D, PRO55B, PRO55D, SER24B, SER24D, SER30B, SER30D, SER32B, SER32D, THR1B, THR1D, THR33B, THR33D, THR34B, THR34D, THR46B, THR46D, TRP244B, TRP244D, TYR47B, TYR47D, VAL19B, VAL19D, VAL21B, VAL21D, VAL25B, VAL25D
• C-D: ALA114C, ALA114D, ALA116C, ALA116D, ALA233C, ALA233D, ALA236C, ALA236D, ALA243C, ALA243D, ALA316C, ALA319C, ALA323C, ALA323D, ALA332C, ALA332D, ALA346C, ALA41C, ALA41D, ALA81C, ALA81D, ALA84C, ALA84D, ARG108C, ARG108D, ARG51C, ARG51D, ARG57C, ARG57D, ASN115C, ASN115D, ASN206C, ASN206D, ASN232C, ASN232D, ASN42D, ASN54C, ASN54D, ASP210C, ASP210D, ASP242C, ASP242D, GLN228D, GLN231C, GLN231D, GLN37C, GLN37D, GLN53D, GLN88C, GLN88D, GLN92C, GLN92D, GLU317C, GLU333C, GLU333D, GLU339C, GLU339D, GLU343C, GLU48C, GLU48D, GLY104C, GLY105C, GLY105D, GLY118C, GLY118D, GLY235C, GLY235D, GLY337C, GLY79C, GLY79D, GLY93C, GLY93D, HIS107C, HIS107D, HIS117C, HIS117D, HIS208C, HIS208D, ILE234C, ILE234D, ILE237C, ILE237D, ILE29C, ILE29D, ILE44D, ILE86C, ILE86D, LEU213C, LEU213D, LEU230C, LEU230D, LEU245C, LEU245D, LEU31C, LEU31D, LEU331C, LEU331D, LEU335C, LEU335D, LEU341C, LEU341D, LEU342C, LEU87C, LEU87D, LEU90C, LEU90D, LYS112C, LYS112D, LYS203C, LYS203D, LYS321C, LYS36C, LYS36D, MET348C, MET348D, PHE110C, PHE110D, PHE229C, PHE229D, PHE241C, PHE241D, PHE322C, PHE35C, PHE35D, PHE76C, PHE76D, PRO238C, PRO238D, PRO240C, PRO240D, PRO345C, PRO40C, PRO40D, PRO43D, PRO91C, PRO91D, SER200C, SER200D, SER209C, SER209D, SER239C, SER239D, SER30D, SER320C, SER320D, SER324C, SER324D, SER325C, SER32C, SER32D, SER334C, SER334D, SER38C, SER38D, SER39C, SER39D, SER50C, SER50D, SER52C, SER52D, SER77C, SER77D, SER78C, SER78D, SER80C, SER80D, SER89C, SER89D, SER94C, SER94D, THR106C, THR111C, THR111D, THR202C, THR202D, THR330C, THR330D, THR33C, THR33D, THR349C, THR34C, THR34D, THR82C, THR82D, THR83C, THR83D, THR85C, THR85D, TRP244C, TYR103C, TYR103D, TYR109C, TYR109D, TYR49C, TYR49D, VAL113C, VAL113D, VAL119C, VAL119D, VAL211C, VAL211D, VAL212C, VAL212D, VAL344C, VAL344D, VAL347C, VAL347D, VAL368C