1MS7

x-ray structure of the glur2 ligand-binding core (s1s2j) in complex with (s)-des-me-ampa at 1.97 a resolution, crystallization in the presence of zinc acetate

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 111
  • Norm. En. per Res.: -2.19
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	4.1189	-57.8666	-53.7477	39	2	0	2343	3	25	22
A-C	-45.258	-3.2867	-194.549	-243.0937	111	7	4	9599	4	43	35

Interface residues

• A-B: ALA172A, ALA176A, ARG169A, ARG179A, ARG28A, ARG28B, ASN19A, ASN19B, ASP55A, GLU10A, GLU173A, GLU21A, GLU21B, GLU24B, GLU27B, GLY174A, GLY54A, GLY56A, HIS20A, HIS20B, ILE52A, ILE8A, LEU23B, LEU9A, LYS17A, LYS17B, LYS18A, LYS18B, MET15A, MET16A, MET22B, PRO202A, SER11A, THR170A, THR171A, THR51A, TYR29A, VAL14A, VAL53A
• A-C: ALA150A, ALA220A, ALA220C, ALA230A, ALA230C, ALA234A, ALA234C, ARG146A, ARG146C, ARG93A, ARG93C, ASN211C, ASN229A, ASN229C, ASN232A, ASN232C, ASN239A, ASN239C, ASP213A, ASP213C, ASP245A, ASP245C, ASP98A, ASP98C, GLN241A, GLN241C, GLU142A, GLU142C, GLU240A, GLU240C, GLU94A, GLU94C, GLU95A, GLU95C, GLY216A, GLY216C, GLY218A, GLY218C, GLY242A, GLY242C, ILE149A, ILE149C, ILE219A, ILE219C, ILE89A, ILE89C, ILE97A, ILE97C, LEU106A, LEU106C, LEU212A, LEU212C, LEU233A, LEU233C, LEU236A, LEU236C, LEU238A, LEU238C, LEU243A, LEU243C, LEU244A, LEU244C, LEU91A, LEU91C, LYS101A, LYS101C, LYS148A, LYS148C, LYS215A, LYS215C, LYS223A, LYS223C, LYS237A, LYS237C, LYS246A, LYS246C, LYS248A, MET104A, MET104C, PHE103A, PHE103C, PHE143A, PHE143C, PHE152A, PHE152C, PHE99A, PHE99C, PRO102A, PRO102C, SER100A, SER100C, SER105A, SER105C, SER139A, SER139C, SER147A, SER147C, SER214A, SER214C, THR88A, THR88C, THR90A, THR90C, TYR217A, TYR217C, VAL235A, VAL235C, VAL92A, VAL92C, VAL96A, VAL96C