1MLD

refined structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 164
  • Norm. En. per Res.: -4.0492
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-88.7254	-142.1726	-433.17	-664.0681	164	10	17	17867	11	38	39
A-C	-9.8249	20.9337	-95.4842	-84.3754	50	3	0	3991	0	12	10
A-D	0.0	0.0	-0.0936	-0.0936	4	0	0	26	0	0	1
B-C	0.0	0.0	-0.0015	-0.0015	2	0	0	4	0	0	1
B-D	-6.541	21.7277	-94.4845	-79.2978	51	4	0	3982	0	12	10
C-D	-82.4519	-107.6237	-437.883	-627.9587	163	9	16	17711	8	42	37

Interface residues

• A-B: ALA153A, ALA153B, ALA155A, ALA155B, ALA158A, ALA158B, ALA166A, ALA166B, ALA209A, ALA209B, ALA216A, ALA216B, ALA218A, ALA218B, ALA220A, ALA220B, ALA223A, ALA223B, ALA228A, ALA228B, ALA230A, ALA230B, ALA232A, ALA232B, ALA41A, ALA41B, ALA42A, ALA42B, ALA51A, ALA51B, ALA8A, ALA8B, ARG152A, ARG152B, ARG167A, ARG167B, ARG205A, ARG205B, ARG233A, ARG233B, ARG50A, ARG50B, ASN154A, ASN154B, ASN22A, ASN22B, ASP149A, ASP149B, ASP164A, ASP164B, ASP43A, ASP43B, GLN14A, GLN14B, GLU159A, GLU159B, GLU208A, GLU208B, GLU212A, GLU212B, GLU48A, GLU48B, GLY10A, GLY11A, GLY11B, GLY13A, GLY13B, GLY162A, GLY210A, GLY210B, GLY219A, GLY219B, GLY221A, GLY221B, GLY39A, GLY39B, HIS36A, HIS36B, HIS46A, HIS46B, ILE12A, ILE150A, ILE150B, ILE206A, ILE206B, ILE47A, ILE47B, LEU148A, LEU148B, LEU163A, LEU163B, LEU16A, LEU16B, LEU18A, LEU18B, LEU19A, LEU19B, LEU225A, LEU225B, LEU29A, LEU29B, LEU31A, LEU31B, LEU44A, LEU44B, LYS215A, LYS215B, LYS217A, LYS217B, LYS21A, LYS21B, MET227A, MET227B, PHE156A, PHE156B, PHE236A, PHE236B, PRO15A, PRO15B, PRO165A, PRO165B, PRO24A, PRO24B, PRO38A, PRO38B, SER169A, SER169B, SER17A, SER17B, SER222A, SER222B, SER226A, SER226B, SER45A, SER45B, SER9A, SER9B, THR147A, THR147B, THR211A, THR211B, THR224A, THR224B, THR37A, THR37B, THR49A, THR49B, THR52A, THR52B, TYR229A, TYR229B, VAL151A, VAL151B, VAL168A, VAL168B, VAL170A, VAL170B, VAL213A, VAL213B, VAL214A, VAL214B, VAL40A, VAL40B, VAL53A
• A-C: ALA218A, ALA218C, ALA35A, ALA94A, ALA94C, ARG80A, ARG80C, ARG86A, ARG86C, ASN91A, ASN91C, ASN93A, ASN93C, ASP87A, ASP87C, ASP88A, ASP88C, GLY219A, GLY219C, GLY77A, GLY83A, GLY83C, ILE34A, ILE34C, ILE96A, ILE96C, LEU89A, LEU89C, LYS305A, LYS305C, LYS81A, LYS81C, MET84A, MET84C, PHE309A, PHE90A, PHE90C, PRO79A, PRO79C, PRO82A, PRO82C, THR85A, THR85C, THR92A, THR92C, THR95A, THR95C, VAL214C, VAL78A, VAL78C
• A-D: ALA35A, ALA35D, HIS36A, HIS36D
• B-C: HIS36B, HIS36C
• B-D: ALA218B, ALA218D, ALA35D, ALA94B, ALA94D, ARG80B, ARG80D, ARG86B, ARG86D, ASN91B, ASN91D, ASN93B, ASN93D, ASP87B, ASP87D, ASP88B, ASP88D, GLY219B, GLY219D, GLY77B, GLY77D, GLY83B, GLY83D, ILE34B, ILE34D, ILE96B, ILE96D, LEU89B, LEU89D, LYS305B, LYS305D, LYS81B, LYS81D, MET84B, MET84D, PHE309D, PHE90B, PHE90D, PRO79B, PRO79D, PRO82B, PRO82D, THR85B, THR85D, THR92B, THR92D, THR95B, THR95D, VAL214B, VAL78B, VAL78D
• C-D: ALA153C, ALA153D, ALA155C, ALA155D, ALA158C, ALA158D, ALA166C, ALA166D, ALA209C, ALA209D, ALA216C, ALA216D, ALA218C, ALA218D, ALA220C, ALA220D, ALA223C, ALA223D, ALA228C, ALA228D, ALA230C, ALA230D, ALA232C, ALA232D, ALA41C, ALA41D, ALA42C, ALA42D, ALA51C, ALA51D, ALA8C, ALA8D, ARG152C, ARG152D, ARG167C, ARG167D, ARG205C, ARG205D, ARG233C, ARG233D, ARG50C, ARG50D, ASN154C, ASN154D, ASN22C, ASN22D, ASP149C, ASP149D, ASP164C, ASP164D, ASP43C, ASP43D, GLN14C, GLN14D, GLU159C, GLU159D, GLU208C, GLU208D, GLU212C, GLU212D, GLU48C, GLU48D, GLY10C, GLY10D, GLY11D, GLY13C, GLY13D, GLY210C, GLY210D, GLY219C, GLY219D, GLY221C, GLY221D, GLY39C, GLY39D, HIS36C, HIS36D, HIS46C, HIS46D, ILE12D, ILE150C, ILE150D, ILE206C, ILE206D, ILE47C, ILE47D, LEU148C, LEU148D, LEU163C, LEU163D, LEU16C, LEU16D, LEU18C, LEU18D, LEU19C, LEU19D, LEU225C, LEU225D, LEU29C, LEU31C, LEU31D, LEU44C, LEU44D, LYS215C, LYS215D, LYS217C, LYS217D, LYS21C, LYS21D, MET227C, MET227D, PHE156C, PHE156D, PHE236C, PHE236D, PRO15C, PRO15D, PRO165C, PRO165D, PRO24C, PRO24D, PRO38C, PRO38D, SER169C, SER169D, SER17C, SER17D, SER222C, SER222D, SER226C, SER226D, SER45C, SER45D, SER9C, SER9D, THR147C, THR147D, THR211C, THR211D, THR224C, THR224D, THR37C, THR37D, THR49C, THR49D, THR52C, THR52D, TYR229C, TYR229D, VAL151C, VAL151D, VAL168C, VAL168D, VAL170C, VAL170D, VAL213C, VAL213D, VAL214C, VAL214D, VAL40C, VAL40D, VAL53C, VAL53D