1MK7

crystal structure of an integrin beta3-talin chimera

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 45
  • Norm. En. per Res.: -4.7111
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-16.8723	0.0	-27.1093	-43.9816	23	20	4	3025	0	2	2
A-D	-34.9592	2.1761	-188.702	-221.4851	51	6	3	6077	0	6	8
B-C	-47.6378	2.7529	-167.114	-211.9989	45	6	2	5543	0	6	8
B-D	-35.7948	1.9801	-71.2607	-105.0755	64	4	0	3300	2	28	13
C-D	-24.4799	0.0	-13.9051	-38.385	25	26	4	3322	0	2	3

Interface residues

• A-B: ARG297B, ARG303B, ASN213B, ASN744A, GLN211B, GLU293B, GLU749A, ILE292B, LEU212B, LEU214B, LEU215B, LEU746A, LYS295B, LYS300B, LYS748A, PRO209B, PRO745A, TYR216B, TYR298B, TYR747A, VAL210B, VAL296B, VAL299B
• A-D: ALA360D, ALA361D, ALA389D, ALA393D, ALA742A, ARG358D, ASN355D, ASN743A, ASN744A, ASP369D, ASP372D, ASP397D, ASP740A, CB8.55989-8.75407, CB8.6272013.65934, GLU386D, GLU749A, GLY371D, GLY376D, HIS737A, HIS737A5, ILE356D, ILE392D, ILE396D, ILE399D, LEU353D, LEU368D, LEU400D, LEU746A, LYS318D, LYS357D, LYS748A, MET738A, PHE366D, PHE370D, PRO363D, PRO745A, SER352D, SER362D, SER365D, SER379D, THR354D, THR367D, THR741A, TRP359D, TRP739A, TYR373D, TYR377D, TYR378D, TYR747A, VAL380D
• B-C: ALA360B, ALA361B, ALA389B, ALA393B, ALA742C, ARG358B, ASN355B, ASN743C, ASN744C, ASP369B, ASP372B, ASP397B, ASP740C, GLY371B, HIS737C, ILE356B, ILE392B, ILE396B, ILE399B, LEU353B, LEU368B, LEU400B, LEU746C, LYS357B, LYS748C, MET738C, PHE366B, PHE370B, PRO363B, PRO745C, SER352B, SER362B, SER365B, SER379B, SER736C, THR354B, THR367B, THR741C, TRP359B, TRP739C, TYR373B, TYR377B, TYR378B, TYR747C, VAL380B
• B-D: ARG297B, ARG297D, ARG303B, ARG303D, ASN355B, ASN355D, ASP369B, ASP369D, ASP372B, ASP372D, ASP375B, GLN374B, GLN374D, GLU293B, GLU293D, GLU335B, GLU335D, GLU350B, GLU350D, GLY371B, GLY371D, ILE356B, ILE356D, ILE399B, ILE399D, LEU215B, LEU215D, LEU301B, LEU301D, LEU305D, LEU353B, LEU353D, LEU400B, LEU400D, LYS300B, LYS300D, LYS306B, LYS306D, LYS334B, LYS334D, LYS357B, LYS357D, MET289B, PHE370B, PHE370D, SER304B, SER304D, SER352B, SER352D, THR333D, THR354B, THR354D, TRP351B, TRP351D, TYR241B, TYR308B, TYR308D, TYR373B, TYR373D, VAL296B, VAL296D, VAL299B, VAL299D, VAL347D
• C-D: ARG297D, ARG303D, ASN213D, ASN743C, ASN744C, GLN211D, GLU293D, GLU749C, ILE292D, LEU212D, LEU214D, LEU215D, LEU301D, LEU746C, LYS295D, LYS300D, LYS748C, PRO209D, PRO745C, TYR216D, TYR298D, TYR747C, VAL210D, VAL296D, VAL299D