1MHJ

solution structure of the superactive monomeric des- [phe(b25)] human insulin mutant. elucidation of the structural basis for the monomerization of the des- [phe(b25)] insulin and the dimerization of native insulin

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 49
  • Norm. En. per Res.: 27.8176
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-39.6058	0.0	1402.67	1363.0642	49	62	4	8386	0	4	0

Interface residues

• A-B: ALA14B, ARG22B, ASN18A, ASN21A, ASN3B, CYS11A, CYS19B, CYS20A, CYS6A, CYS7A, CYS7B, GLN15A, GLN4B, GLN5A, GLU13B, GLU17A, GLU21B, GLU4A, GLY1A, GLY20B, GLY23B, GLY8B, HIS10B, HIS5B, ILE10A, ILE2A, LEU11B, LEU13A, LEU15B, LEU16A, LEU17B, LEU6B, LYS28B, PHE1B, PHE24B, PRO27B, SER12A, SER9A, THR26B, THR29B, THR8A, TYR14A, TYR16B, TYR19A, TYR25B, VAL12B, VAL18B, VAL2B, VAL3A