1MDU

crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (gs-1)

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: D-E
  • Int. Res.: 97
  • Norm. En. per Res.: -3.0487
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-36.0572	59.1655	-288.8	-265.6917	99	17	8	11184	0	17	17
A-D	0.0	0.0	-0.1141	-0.1141	7	0	0	40	0	0	0
A-E	-16.9148	6.5699	-144.889	-155.2338	81	10	0	6457	0	16	18
D-E	-64.4924	60.9134	-292.144	-295.7231	97	18	8	11181	0	15	16

Interface residues

• A-B: ALA146B, ALA24B, ALA28B, ALA297B, ALA349B, ALA76A, ALA77A, ALA78A, ALA92A, ARG149B, ARG337B, ARG91A, ARG96A, ASN298B, ASP26A, ASP26B, ASP27B, ASP294B, ASP72A, ASP85A, ASP86A, CYS69A, GLN355B, GLN356B, GLN71A, GLN83A, GLN94A, GLU169B, GLU23A, GLU336B, GLU4A, GLU73A, GLU7A, GLU97A, GLY124A, GLY148B, GLY170B, GLY25B, GLY344B, GLY345B, GLY75A, GLY90A, HIS5A, HIS95A, ILE167B, ILE332B, ILE343B, ILE347B, ILE79A, LEU142B, LEU144B, LEU27A, LEU348B, LEU351B, LEU61A, LEU65A, LEU84A, LYS24A, LYS330B, MET357B, PHE101A, PHE125A, PHE23B, PHE25A, PHE354B, PHE80A, PHE8A, PRO334B, PRO335B, PRO6A, SER123A, SER143B, SER147B, SER340B, SER346B, SER350B, SER352B, SER70A, SER74A, THR150B, THR151B, THR353B, THR81A, TRP342B, TYR145B, TYR168B, TYR171B, TYR339B, TYR63A, VAL141B, VAL22A, VAL28A, VAL2A, VAL300B, VAL341B, VAL3A, VAL82A, VAL93A, VAL98A
• A-D: ARG91A, ARG96D, ASN54A, ASN56A, ASN67D, PHE101D, VAL98D
• A-E: ALA222E, ALA230E, ALA232E, ALA233E, ALA297E, ALA312E, ALA321E, ALA323E, ALA333E, ARG149E, ARG256E, ARG314E, ARG337E, ARG53A, ARG91A, ASN227E, ASN298E, ASN299E, ASN33A, ASN54A, ASN56A, ASP224E, ASP313E, GLN316E, GLN51A, GLU14A, GLU226E, GLU228E, GLU318E, GLU336E, GLY113A, GLY12A, GLY16A, GLY310E, GLY36A, GLY55A, ILE311E, ILE329E, ILE331E, ILE332E, LEU17A, LEU223E, LEU238E, LEU34A, LEU52A, LEU57A, LEU9A, LYS10A, LYS111A, LYS13A, LYS317E, LYS328E, LYS330E, LYS48A, MET301E, MET307E, MET315E, MET327E, PHE110A, PRO15A, PRO31A, PRO324E, PRO334E, PRO335E, SER112A, SER147E, SER234E, SER235E, SER236E, SER237E, SER325E, THR231E, THR320E, THR326E, THR32A, THR49A, TYR220E, TYR35A, TYR59A, VAL300E, VAL50A
• D-E: ALA146E, ALA24E, ALA28E, ALA297E, ALA349E, ALA76D, ALA77D, ALA78D, ALA92D, ARG149E, ARG337E, ARG91D, ARG96D, ASN298E, ASP26D, ASP26E, ASP27E, ASP294E, ASP72D, ASP85D, ASP86D, CYS69D, GLN355E, GLN356E, GLN71D, GLN83D, GLN94D, GLU169E, GLU23D, GLU336E, GLU4D, GLU73D, GLU7D, GLU97D, GLY124D, GLY148E, GLY170E, GLY25E, GLY344E, GLY345E, GLY75D, GLY90D, HIS5D, HIS95D, ILE167E, ILE332E, ILE343E, ILE347E, ILE79D, LEU106E, LEU142E, LEU144E, LEU27D, LEU348E, LEU351E, LEU61D, LEU65D, LEU84D, LYS24D, LYS330E, MET357E, PHE125D, PHE23E, PHE25D, PHE354E, PHE80D, PHE8D, PRO334E, PRO335E, PRO6D, SER123D, SER143E, SER147E, SER340E, SER346E, SER350E, SER352E, SER70D, SER74D, THR150E, THR151E, THR353E, THR81D, TRP342E, TYR135E, TYR145E, TYR168E, TYR171E, TYR339E, TYR63D, VAL141E, VAL22D, VAL300E, VAL3D, VAL82D, VAL93D, VAL98D