1M7W

hnf4a ligand binding domain with bound fatty acid

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 117
  • Norm. En. per Res.: -2.6348
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.9341	-50.9947	-231.346	-308.2748	117	8	4	10439	4	38	43
A-C	0.0	0.0	-11.0472	-11.0472	11	1	0	646	0	0	0
B-C	-10.222	38.7855	-152.237	-123.6735	94	14	7	8180	3	17	24
B-D	0.0	0.0	-18.7193	-18.7193	12	5	0	899	0	0	0
C-D	-25.4542	6.3749	-225.092	-244.1713	114	9	3	9806	3	39	39

Interface residues

• A-B: ALA290A, ALA290B, ARG254A, ARG258A, ARG258B, ARG301A, ARG301B, ARG303A, ARG303B, ARG322A, ARG322B, ARG324A, ARG324B, ASN315A, ASN315B, ASP261A, ASP261B, ASP287A, ASP287B, ASP289A, ASP289B, ASP312A, ASP312B, GLN305A, GLN305B, GLN307A, GLN307B, GLN336A, GLN336B, GLN341A, GLN341B, GLN347B, GLU217A, GLU217B, GLU262A, GLU262B, GLU269A, GLU269B, GLU311A, GLU311B, GLU327A, GLU327B, GLU344A, GLU344B, GLY323A, GLY323B, GLY326A, GLY326B, HIS214A, HIS214B, ILE283A, ILE283B, ILE284A, ILE284B, ILE314A, ILE314B, ILE338A, ILE338B, ILE343B, LEU263A, LEU263B, LEU265A, LEU265B, LEU270A, LEU270B, LEU280A, LEU280B, LEU310A, LEU310B, LEU328A, LEU328B, LEU329A, LEU329B, LEU330A, LEU330B, LEU331A, LEU331B, LEU332A, LEU332B, LEU335A, LEU335B, LYS291A, LYS291B, LYS300A, LYS300B, MET342B, PHE286A, PHE286B, PHE325A, PHE325B, PRO266A, PRO266B, PRO288A, PRO288B, PRO296B, PRO333A, PRO333B, SER304A, SER304B, SER309A, SER309B, SER321A, SER321B, SER337A, SER337B, THR334A, THR334B, THR339A, THR339B, TRP340A, TRP340B, TYR313A, TYR313B, VAL306A, VAL306B, VAL308A, VAL308B
• A-C: ASP358C, GLN362C, GLY353A, LEU351A, LEU360C, LEU361C, LEU365C, MET354A, MET364C, PHE348A, PHE352A
• B-C: ALA193B, ALA193C, ALA209B, ALA209C, ARG212B, ARG212C, ARG226B, ARG226C, ASN238B, ASN238C, ASN359C, ASP205B, ASP205C, ASP206B, ASP206C, ASP358B, CYS179B, CYS179C, CYS200B, CYS200C, GLN154B, GLN154C, GLN155B, GLN155C, GLN185B, GLN185C, GLN207B, GLN207C, GLN347C, GLU180B, GLU180C, GLU184B, GLU184C, GLU191B, GLU191C, GLU201B, GLU201C, GLY237B, GLY237C, GLY292B, GLY292C, ILE156B, ILE156C, LEU152C, LEU186B, LEU186C, LEU187B, LEU187C, LEU189B, LEU189C, LEU202B, LEU202C, LEU203B, LEU203C, LEU204B, LEU204C, LEU210C, LEU211B, LEU211C, LEU351B, LEU351C, LEU361B, LYS183B, LYS183C, LYS194B, LYS194C, LYS291B, LYS350B, LYS350C, MET182B, MET182C, MET354B, MET354C, PHE199B, PHE199C, PHE285C, PRO197C, SER153B, SER153C, SER158C, SER181B, SER181C, THR157B, THR157C, TRP192B, TRP192C, TYR195B, TYR195C, VAL188B, VAL188C, VAL190B, VAL190C, VAL208B, VAL208C
• B-D: GLN362B, GLY353D, ILE349D, ILE357B, LEU351D, LEU360B, LEU361B, LEU365B, MET354D, MET364B, PHE348D, PHE352D
• C-D: ALA290C, ALA290D, ARG258C, ARG258D, ARG301C, ARG301D, ARG303C, ARG303D, ARG322C, ARG322D, ARG324C, ARG324D, ASN315C, ASN315D, ASP261C, ASP261D, ASP287C, ASP287D, ASP289C, ASP289D, ASP312C, ASP312D, GLN305C, GLN305D, GLN307C, GLN307D, GLN336C, GLN336D, GLN341C, GLN341D, GLU217C, GLU217D, GLU262C, GLU262D, GLU269C, GLU269D, GLU311C, GLU311D, GLU327C, GLU327D, GLU344C, GLU344D, GLY297C, GLY323C, GLY323D, GLY326C, GLY326D, HIS214C, HIS214D, ILE283C, ILE283D, ILE284C, ILE284D, ILE314D, ILE338C, ILE338D, ILE343C, LEU263C, LEU263D, LEU265C, LEU265D, LEU270C, LEU270D, LEU280C, LEU280D, LEU310C, LEU310D, LEU328C, LEU328D, LEU329C, LEU329D, LEU330C, LEU330D, LEU331C, LEU331D, LEU332C, LEU332D, LEU335C, LEU335D, LYS291C, LYS291D, LYS300C, LYS300D, MET342C, PHE286C, PHE286D, PHE325C, PHE325D, PRO266C, PRO266D, PRO288C, PRO288D, PRO296C, PRO296D, PRO333C, PRO333D, SER304C, SER304D, SER309D, SER321C, SER321D, SER337C, SER337D, THR334C, THR334D, THR339C, THR339D, TRP340C, TRP340D, TYR313D, VAL306C, VAL306D, VAL308C, VAL308D