1M1N

nitrogenase mofe protein from azotobacter vinelandii

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: F-H
  • Int. Res.: 271
  • Norm. En. per Res.: -4.4691
• Hub Node: B(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-222.1949	-52.3854	-1328.3	-1602.8803	412	45	38	52776	16	122	100
A-D	-54.8158	-65.5822	-318.787	-439.185	133	10	6	12864	5	39	39
B-C	-49.1609	-65.4102	-328.685	-443.2561	136	10	6	13004	6	37	39
B-D	-229.4221	-129.5337	-854.899	-1213.8548	276	43	8	32135	25	180	169
B-E	0.0	0.0	-8.4782	-8.4782	28	1	0	546	0	5	5
B-F	-5.9668	-16.6789	-8.8764	-31.5222	16	1	0	584	1	8	8
B-H	0.0	10.4538	-0.2993	10.1544	3	0	0	22	0	3	9
C-D	-227.4302	-50.9738	-1330.09	-1608.494	414	46	38	52605	16	120	101
D-E	0.0	18.5132	-3.1354	15.3778	18	0	0	460	0	12	14
E-F	-221.9899	-48.987	-1324.29	-1595.2669	413	44	38	52710	17	123	101
E-H	-49.8095	-64.9544	-322.222	-436.986	134	12	6	12859	5	39	40
F-G	-65.7283	-68.4129	-325.75	-459.8912	135	13	6	12815	5	37	39
F-H	-230.9286	-121.918	-858.267	-1211.1136	271	42	8	32136	22	182	168
G-H	-238.4066	-49.8312	-1330.48	-1618.7178	414	46	39	52864	16	122	99

Interface residues

• A-B: ALA108A, ALA10B, ALA122B, ALA123B, ALA132A, ALA140B, ALA155B, ALA217A, ALA235A, ALA24A, ALA251A, ALA25B, ALA265B, ALA337A, ALA340A, ALA457A, ALA460A, ALA477A, ALA61B, ALA63A, ALA65A, ALA67B, ALA69B, ALA94A, ALA97B, ARG100B, ARG105B, ARG108B, ARG187A, ARG210A, ARG239A, ARG248A, ARG25A, ARG270B, ARG28A, ARG28B, ARG431B, ARG453B, ARG461A, ARG481B, ARG59B, ARG60A, ARG93A, ARG96A, ARG97A, ASN104B, ASN107A, ASN113A, ASN130B, ASN137B, ASN145A, ASN230A, ASN397B, ASN445B, ASN56B, ASN65B, ASP116B, ASP117A, ASP121B, ASP122A, ASP133B, ASP136A, ASP17B, ASP19B, ASP222A, ASP22B, ASP234A, ASP256A, ASP262B, ASP266B, ASP27A, ASP29B, ASP38B, ASP403A, ASP41B, ASP426B, ASP445A, ASP454A, ASP454B, ASP462A, ASP6B, ASP77A, CYS113B, CYS138B, CYS153B, CYS154A, CYS249A, CYS471A, CYS62A, CYS70B, CYS88A, CYS95B, GLN119A, GLN129B, GLN136B, GLN18B, GLN191A, GLN252A, GLN268B, GLN37B, GLN3B, GLN432A, GLN45B, GLN476A, GLN4B, GLN53A, GLN53B, GLN58B, GLN71B, GLN90A, GLN93B, GLU109B, GLU120A, GLU120B, GLU137A, GLU139A, GLU153A, GLU156B, GLU184A, GLU18A, GLU22A, GLU243A, GLU244A, GLU259B, GLU261A, GLU263A, GLU32B, GLU334A, GLU336A, GLU33B, GLU380A, GLU408A, GLU410A, GLU411A, GLU427A, GLU42B, GLU440A, GLU480A, GLU51B, GLU54B, GLU60B, GLY102A, GLY105A, GLY127A, GLY134B, GLY147A, GLY157A, GLY159B, GLY160A, GLY185A, GLY188A, GLY191B, GLY232A, GLY233A, GLY246A, GLY255A, GLY257A, GLY267B, GLY30B, GLY406A, GLY424A, GLY424B, GLY435A, GLY448A, GLY448B, GLY452A, GLY455A, GLY55A, GLY61A, GLY66A, GLY69A, GLY74B, GLY84A, GLY87A, GLY89A, GLY91B, GLY94B, GLY95A, HIS106B, HIS193B, HIS396B, HIS429B, HIS442A, HIS451A, HIS457B, HIS477B, HIS478B, HIS480B, HIS80A, HIS83A, HIS90B, ILE101A, ILE123A, ILE135A, ILE147B, ILE148A, ILE156A, ILE158B, ILE159A, ILE225A, ILE231A, ILE240A, ILE259A, ILE262A, ILE40B, ILE425A, ILE430A, ILE436A, ILE451B, ILE458A, ILE59A, ILE79A, ILE81A, ILE8B, LEU131A, LEU134A, LEU135B, LEU141A, LEU144A, LEU14B, LEU158A, LEU16B, LEU193A, LEU241A, LEU242A, LEU247A, LEU24B, LEU261B, LEU264A, LEU427B, LEU475A, LEU55B, LEU56A, LEU62B, LEU73B, LYS121A, LYS129A, LYS130A, LYS132B, LYS133A, LYS139B, LYS143B, LYS146A, LYS176A, LYS21B, LYS23A, LYS26B, LYS27B, LYS330A, LYS341A, LYS34B, LYS39B, LYS414A, LYS426A, LYS428A, LYS433A, LYS449B, LYS474A, LYS50A, LYS51A, LYS68A, LYS68B, LYS76A, LYS7B, LYS9B, MET112A, MET118B, MET131B, MET154B, MET23B, MET271B, MET434A, MET465A, MET57A, MET86B, PHE103B, PHE107B, PHE109A, PHE114A, PHE118A, PHE142A, PHE15B, PHE174B, PHE186A, PHE189B, PHE216A, PHE230B, PHE269B, PHE31B, PHE381A, PHE409A, PHE429A, PHE431A, PHE44B, PHE450B, PHE453A, PHE456A, PHE459A, PHE471B, PHE474B, PHE57B, PHE99B, PRO110B, PRO13B, PRO143A, PRO155A, PRO187B, PRO21A, PRO264B, PRO333A, PRO36B, PRO449A, PRO472B, PRO54A, PRO66B, PRO72B, PRO85A, PRO87B, SER101B, SER112B, SER115B, SER116A, SER117B, SER11B, SER188B, SER190A, SER192A, SER192B, SER218A, SER237A, SER238A, SER254A, SER258A, SER260A, SER2B, SER432B, SER443A, SER446B, SER447A, SER52A, SER67A, SER82A, SER92A, SER92B, THR103A, THR104A, THR111A, THR115A, THR119B, THR140A, THR141B, THR152B, THR215A, THR219A, THR263B, THR405A, THR47B, THR48B, THR58A, THR63B, TRP236A, TRP335A, TRP370B, TRP428B, TRP444A, TRP46B, TRP472A, TYR100A, TYR102B, TYR12B, TYR142B, TYR20A, TYR20B, TYR272B, TYR331A, TYR342A, TYR35B, TYR407A, TYR446A, TYR447B, TYR450A, TYR52B, TYR64A, TYR88B, TYR91A, TYR98B, TYR99A, VAL106A, VAL110A, VAL111B, VAL114B, VAL124A, VAL124B, VAL138A, VAL157B, VAL16A, VAL189A, VAL190B, VAL19A, VAL250A, VAL260B, VAL268A, VAL338A, VAL339A, VAL404A, VAL43B, VAL5B, VAL64B, VAL70A, VAL86A, VAL89B, VAL96B
• A-D: ALA108A, ALA342D, ALA477A, ALA514D, ALA94A, ARG345A, ARG348D, ARG350D, ARG439A, ARG461A, ARG523D, ARG93A, ARG96A, ARG97A, ASN107A, ASN230A, ASN468A, ASN469A, ASN518D, ASN98A, ASP256A, ASP323D, ASP326D, ASP353D, ASP357D, ASP445A, ASP462A, ASP464A, ASP516D, ASP520D, CYS388D, CYS471A, GLN432A, GLN476A, GLN513D, GLN90A, GLU327D, GLU347D, GLU385D, GLU440A, GLU480A, GLY102A, GLY105A, GLY232A, GLY233A, GLY349D, GLY364D, GLY387D, GLY435A, GLY448A, GLY511D, GLY95A, HIS359D, HIS363D, HIS519D, ILE101A, ILE340D, ILE425A, ILE436A, LEU322D, LEU329D, LEU344D, LEU351D, LEU362D, LEU383D, LEU384D, LEU386D, LEU420A, LEU467A, LEU475A, LEU502D, LEU505D, LEU521D, LYS341A, LYS346D, LYS365D, LYS381D, LYS417D, LYS428A, LYS433A, LYS473A, LYS474A, LYS76A, MET330D, MET354D, MET355D, MET434A, MET463A, MET465A, MET512D, PHE328D, PHE429A, PHE431A, PHE438A, PRO339D, PRO341D, PRO414D, PRO437A, PRO449A, PRO470A, PRO478A, SER333D, SER358D, SER413D, SER443A, SER447A, SER92A, THR103A, THR104A, THR111A, THR325D, THR345D, THR356D, THR360D, THR466A, THR509D, THR515D, TRP236A, TRP361D, TRP444A, TRP472A, TRP479A, TYR100A, TYR342A, TYR415D, TYR446A, TYR487D, TYR517D, TYR91A, TYR99A, VAL106A, VAL352D, VAL522D
• B-C: ALA108C, ALA342B, ALA477C, ALA514B, ALA94C, ARG345C, ARG348B, ARG350B, ARG439C, ARG461C, ARG523B, ARG93C, ARG96C, ARG97C, ASN107C, ASN230C, ASN468C, ASN469C, ASN518B, ASN98C, ASP256C, ASP323B, ASP326B, ASP353B, ASP357B, ASP445C, ASP462C, ASP464C, ASP516B, ASP520B, CYS388B, CYS471C, GLN432C, GLN476C, GLN513B, GLN90C, GLU327B, GLU347B, GLU385B, GLU440C, GLU480C, GLY102C, GLY105C, GLY232C, GLY233C, GLY321B, GLY349B, GLY364B, GLY387B, GLY435C, GLY448C, GLY511B, GLY95C, HIS359B, HIS363B, HIS519B, ILE101C, ILE340B, ILE425C, ILE436C, LEU322B, LEU329B, LEU344B, LEU351B, LEU362B, LEU383B, LEU384B, LEU386B, LEU420C, LEU467C, LEU475C, LEU502B, LEU505B, LEU521B, LYS341C, LYS346B, LYS365B, LYS381B, LYS417B, LYS428C, LYS433C, LYS473C, LYS474C, LYS76C, MET330B, MET354B, MET355B, MET434C, MET463C, MET465C, MET512B, PHE328B, PHE382B, PHE429C, PHE431C, PHE438C, PRO339B, PRO341B, PRO414B, PRO437C, PRO449C, PRO470C, PRO478C, SER333B, SER358B, SER413B, SER443C, SER447C, SER92C, THR103C, THR104C, THR111C, THR325B, THR345B, THR356B, THR360B, THR466C, THR509B, THR515B, TRP236C, TRP324B, TRP361B, TRP444C, TRP472C, TRP479C, TYR100C, TYR342C, TYR415B, TYR446C, TYR487B, TYR517B, TYR91C, TYR99C, VAL106C, VAL352B, VAL522B
• B-D: ALA10B, ALA10D, ALA265B, ALA265D, ALA273B, ALA273D, ALA342B, ALA342D, ALA514B, ALA514D, ARG105B, ARG105D, ARG108B, ARG108D, ARG238B, ARG238D, ARG270B, ARG270D, ARG28B, ARG28D, ARG348B, ARG348D, ARG350B, ARG350D, ARG366B, ARG366D, ARG431B, ARG431D, ARG453B, ARG453D, ARG468B, ARG468D, ARG476B, ARG476D, ARG481B, ARG481D, ARG504B, ARG504D, ARG510B, ARG510D, ARG523B, ARG523D, ASN104D, ASN445B, ASN445D, ASN499B, ASN499D, ASN518B, ASN518D, ASP17B, ASP17D, ASP262B, ASP262D, ASP266B, ASP266D, ASP353B, ASP353D, ASP357B, ASP357D, ASP41B, ASP41D, ASP440B, ASP440D, ASP454B, ASP454D, ASP475B, ASP475D, ASP506B, ASP506D, ASP516B, ASP516D, ASP520B, ASP520D, GLN37B, GLN37D, GLN452B, GLN452D, GLN492B, GLN492D, GLN513B, GLN513D, GLU109B, GLU109D, GLU258B, GLU258D, GLU259B, GLU259D, GLU347B, GLU347D, GLU461B, GLU461D, GLU463B, GLU463D, GLU488B, GLU488D, GLU503B, GLU503D, GLU507B, GLU507D, GLU508B, GLU508D, GLY267B, GLY267D, GLY274B, GLY274D, GLY349B, GLY349D, GLY364B, GLY364D, GLY448B, GLY448D, GLY511B, GLY511D, HIS106B, HIS106D, HIS359B, HIS359D, HIS457B, HIS457D, HIS477B, HIS477D, HIS478B, HIS478D, HIS480B, HIS480D, HIS519B, HIS519D, ILE40B, ILE40D, ILE451B, ILE451D, ILE467D, ILE473B, ILE473D, ILE501B, ILE501D, LEU14B, LEU14D, LEU16B, LEU16D, LEU234B, LEU234D, LEU24B, LEU24D, LEU261B, LEU261D, LEU351B, LEU351D, LEU362B, LEU362D, LEU456B, LEU456D, LEU466B, LEU466D, LEU479B, LEU479D, LEU494B, LEU494D, LEU497B, LEU497D, LEU502B, LEU502D, LEU505B, LEU505D, LEU521B, LEU521D, LYS21B, LYS21D, LYS346B, LYS346D, LYS34B, LYS34D, LYS365B, LYS365D, LYS438B, LYS438D, LYS449B, LYS449D, LYS458B, LYS458D, LYS460B, LYS460D, LYS7B, LYS7D, LYS9B, LYS9D, MET354B, MET354D, MET355B, MET355D, MET491B, MET491D, MET512B, MET512D, PHE107B, PHE107D, PHE15B, PHE15D, PHE435B, PHE435D, PHE44B, PHE44D, PHE450B, PHE450D, PHE474B, PHE474D, PRO110B, PRO110D, PRO13B, PRO13D, PRO257B, PRO257D, PRO264B, PRO264D, PRO465B, PRO465D, PRO472B, PRO472D, SER101B, SER101D, SER11B, SER11D, SER358B, SER358D, SER446B, SER446D, SER482B, SER482D, SER500B, SER500D, THR263B, THR263D, THR345B, THR345D, THR356B, THR356D, THR360B, THR360D, THR455B, THR455D, THR47B, THR47D, THR495B, THR495D, THR496B, THR496D, THR509B, THR509D, THR515B, THR515D, TRP361B, TRP361D, TRP428B, TRP428D, TYR102B, TYR102D, TYR12B, TYR12D, TYR20B, TYR20D, TYR35B, TYR35D, TYR447B, TYR447D, TYR517B, TYR517D, VAL260B, VAL260D, VAL352B, VAL352D, VAL464B, VAL464D, VAL498B, VAL498D, VAL522B, VAL522D
• B-E: ALA342B, ARG248E, ASP317E, GLN338B, GLU243E, GLU244E, GLU326E, GLU334B, GLY246E, GLY248B, GLY337B, ILE240E, ILE320E, ILE335B, LYS222B, LYS322E, LYS323E, LYS330E, PRO220E, PRO339B, PRO341B, SER218E, SER220B, SER319E, SER333B, SER336B, THR219E, TYR221E
• B-F: ASN221B, ASN286B, ASP17F, ASP19F, ASP22F, ASP283B, GLN18F, GLN338B, GLY248B, LYS21F, LYS222B, LYS223B, LYS26F, MET23F, SER220B, TYR20F
• B-H: ASP177B, ASP38H, GLU178B
• C-D: ALA108C, ALA10D, ALA122D, ALA123D, ALA132C, ALA140D, ALA155D, ALA217C, ALA235C, ALA24C, ALA251C, ALA25D, ALA265D, ALA337C, ALA340C, ALA457C, ALA460C, ALA477C, ALA61D, ALA63C, ALA65C, ALA67D, ALA69D, ALA94C, ALA97D, ARG100D, ARG105D, ARG108D, ARG187C, ARG210C, ARG239C, ARG248C, ARG25C, ARG270D, ARG28C, ARG28D, ARG431D, ARG453D, ARG461C, ARG481D, ARG59D, ARG60C, ARG93C, ARG96C, ARG97C, ASN104D, ASN107C, ASN113C, ASN130D, ASN137D, ASN145C, ASN230C, ASN397D, ASN445D, ASN56D, ASN65D, ASP116D, ASP117C, ASP121D, ASP122C, ASP133D, ASP136C, ASP17D, ASP19D, ASP222C, ASP22D, ASP234C, ASP256C, ASP262D, ASP266D, ASP27C, ASP29D, ASP38D, ASP403C, ASP41D, ASP426D, ASP445C, ASP454C, ASP454D, ASP462C, ASP6D, ASP77C, CYS113D, CYS138D, CYS153D, CYS154C, CYS249C, CYS471C, CYS62C, CYS70D, CYS88C, CYS95D, GLN119C, GLN129D, GLN136D, GLN18D, GLN191C, GLN252C, GLN268D, GLN37D, GLN3D, GLN432C, GLN45D, GLN476C, GLN4D, GLN53C, GLN53D, GLN58D, GLN71D, GLN90C, GLN93D, GLU109D, GLU120C, GLU120D, GLU137C, GLU139C, GLU153C, GLU156D, GLU184C, GLU18C, GLU22C, GLU243C, GLU244C, GLU259D, GLU261C, GLU263C, GLU32D, GLU334C, GLU336C, GLU33D, GLU380C, GLU408C, GLU410C, GLU411C, GLU427C, GLU42D, GLU440C, GLU480C, GLU51D, GLU54D, GLU60D, GLY102C, GLY105C, GLY127C, GLY134D, GLY147C, GLY157C, GLY159D, GLY160C, GLY185C, GLY188C, GLY191D, GLY232C, GLY233C, GLY246C, GLY255C, GLY257C, GLY267D, GLY30D, GLY406C, GLY424C, GLY424D, GLY435C, GLY448C, GLY448D, GLY452C, GLY455C, GLY55C, GLY61C, GLY66C, GLY69C, GLY74D, GLY84C, GLY87C, GLY89C, GLY91D, GLY94D, GLY95C, HIS106D, HIS193D, HIS396D, HIS429D, HIS442C, HIS451C, HIS457D, HIS477D, HIS478D, HIS480D, HIS80C, HIS83C, HIS90D, ILE101C, ILE123C, ILE135C, ILE147D, ILE148C, ILE156C, ILE158D, ILE159C, ILE197C, ILE225C, ILE231C, ILE240C, ILE259C, ILE262C, ILE40D, ILE425C, ILE430C, ILE436C, ILE451D, ILE458C, ILE59C, ILE79C, ILE81C, ILE8D, LEU131C, LEU134C, LEU135D, LEU141C, LEU144C, LEU14D, LEU158C, LEU16D, LEU193C, LEU241C, LEU242C, LEU247C, LEU24D, LEU261D, LEU264C, LEU427D, LEU475C, LEU55D, LEU56C, LEU62D, LEU73D, LYS121C, LYS129C, LYS130C, LYS132D, LYS133C, LYS139D, LYS143D, LYS146C, LYS176C, LYS21D, LYS23C, LYS26D, LYS27D, LYS330C, LYS341C, LYS34D, LYS39D, LYS414C, LYS426C, LYS428C, LYS433C, LYS449D, LYS474C, LYS50C, LYS51C, LYS68C, LYS68D, LYS76C, LYS7D, LYS9D, MET112C, MET118D, MET131D, MET154D, MET23D, MET271D, MET434C, MET465C, MET57C, MET86D, PHE103D, PHE107D, PHE109C, PHE114C, PHE118C, PHE125D, PHE142C, PHE15D, PHE174D, PHE186C, PHE189D, PHE216C, PHE230D, PHE269D, PHE31D, PHE381C, PHE409C, PHE429C, PHE431C, PHE44D, PHE450D, PHE453C, PHE456C, PHE459C, PHE471D, PHE474D, PHE57D, PHE99D, PRO110D, PRO13D, PRO143C, PRO155C, PRO187D, PRO21C, PRO264D, PRO333C, PRO36D, PRO449C, PRO472D, PRO54C, PRO66D, PRO72D, PRO85C, PRO87D, SER101D, SER112D, SER115D, SER116C, SER117D, SER11D, SER188D, SER190C, SER192C, SER192D, SER218C, SER237C, SER238C, SER254C, SER258C, SER260C, SER2D, SER432D, SER443C, SER446D, SER447C, SER52C, SER67C, SER82C, SER92C, SER92D, THR103C, THR104C, THR111C, THR115C, THR119D, THR140C, THR141D, THR152D, THR215C, THR219C, THR263D, THR405C, THR47D, THR48D, THR58C, THR63D, TRP236C, TRP335C, TRP370D, TRP428D, TRP444C, TRP46D, TRP472C, TYR100C, TYR102D, TYR12D, TYR142D, TYR20C, TYR20D, TYR272D, TYR331C, TYR342C, TYR35D, TYR407C, TYR446C, TYR447D, TYR450C, TYR52D, TYR64C, TYR88D, TYR91C, TYR98D, TYR99C, VAL106C, VAL110C, VAL111D, VAL114D, VAL124C, VAL124D, VAL138C, VAL157D, VAL16C, VAL189C, VAL190D, VAL19C, VAL250C, VAL260D, VAL268C, VAL338C, VAL339C, VAL404C, VAL43D, VAL5D, VAL64D, VAL70C, VAL86C, VAL89D, VAL96D
• D-E: ASN221D, ASN286D, ASP213E, ASP283D, GLU212E, GLU279D, GLU280D, GLY250D, LYS176E, LYS209E, LYS222D, LYS223D, SER175E, THR214E, THR215E, THR277D, TYR251D, VAL249D
• E-F: ALA108E, ALA10F, ALA122F, ALA123F, ALA132E, ALA140F, ALA155F, ALA217E, ALA235E, ALA24E, ALA251E, ALA25F, ALA265F, ALA337E, ALA340E, ALA457E, ALA460E, ALA477E, ALA61F, ALA63E, ALA65E, ALA67F, ALA69F, ALA94E, ALA97F, ARG100F, ARG105F, ARG108F, ARG187E, ARG210E, ARG239E, ARG248E, ARG25E, ARG270F, ARG28E, ARG28F, ARG431F, ARG453F, ARG461E, ARG481F, ARG59F, ARG60E, ARG93E, ARG96E, ARG97E, ASN104F, ASN107E, ASN113E, ASN130F, ASN137F, ASN145E, ASN230E, ASN397F, ASN445F, ASN56F, ASN65F, ASP116F, ASP117E, ASP121F, ASP122E, ASP133F, ASP136E, ASP17F, ASP19F, ASP222E, ASP22F, ASP234E, ASP256E, ASP262F, ASP266F, ASP27E, ASP29F, ASP38F, ASP403E, ASP41F, ASP426F, ASP445E, ASP454E, ASP454F, ASP462E, ASP6F, ASP77E, CYS113F, CYS138F, CYS153F, CYS154E, CYS249E, CYS471E, CYS62E, CYS70F, CYS88E, CYS95F, GLN119E, GLN129F, GLN136F, GLN18F, GLN191E, GLN252E, GLN268F, GLN37F, GLN3F, GLN432E, GLN45F, GLN476E, GLN4F, GLN53E, GLN53F, GLN58F, GLN71F, GLN90E, GLN93F, GLU109F, GLU120E, GLU120F, GLU137E, GLU139E, GLU153E, GLU156F, GLU184E, GLU18E, GLU22E, GLU243E, GLU244E, GLU259F, GLU261E, GLU263E, GLU32F, GLU334E, GLU336E, GLU33F, GLU380E, GLU408E, GLU410E, GLU411E, GLU427E, GLU42F, GLU440E, GLU480E, GLU51F, GLU54F, GLU60F, GLY102E, GLY105E, GLY127E, GLY134F, GLY147E, GLY157E, GLY159F, GLY160E, GLY185E, GLY188E, GLY191F, GLY232E, GLY233E, GLY246E, GLY255E, GLY257E, GLY267F, GLY30F, GLY406E, GLY424E, GLY424F, GLY435E, GLY448E, GLY448F, GLY452E, GLY455E, GLY55E, GLY61E, GLY66E, GLY69E, GLY74F, GLY84E, GLY87E, GLY89E, GLY91F, GLY94F, GLY95E, HIS106F, HIS193F, HIS396F, HIS429F, HIS442E, HIS451E, HIS457F, HIS477F, HIS478F, HIS480F, HIS80E, HIS83E, HIS90F, ILE101E, ILE123E, ILE135E, ILE147F, ILE148E, ILE156E, ILE158F, ILE159E, ILE197E, ILE225E, ILE231E, ILE240E, ILE259E, ILE262E, ILE40F, ILE425E, ILE430E, ILE436E, ILE451F, ILE458E, ILE59E, ILE79E, ILE81E, ILE8F, LEU131E, LEU134E, LEU135F, LEU141E, LEU144E, LEU14F, LEU158E, LEU16F, LEU193E, LEU241E, LEU242E, LEU247E, LEU24F, LEU261F, LEU264E, LEU427F, LEU475E, LEU55F, LEU56E, LEU62F, LEU73F, LYS121E, LYS129E, LYS130E, LYS132F, LYS133E, LYS139F, LYS143F, LYS146E, LYS176E, LYS21F, LYS23E, LYS26F, LYS27F, LYS330E, LYS341E, LYS34F, LYS39F, LYS414E, LYS426E, LYS428E, LYS433E, LYS449F, LYS474E, LYS50E, LYS51E, LYS68E, LYS68F, LYS76E, LYS7F, LYS9F, MET112E, MET118F, MET131F, MET154F, MET23F, MET271F, MET434E, MET465E, MET57E, MET86F, PHE103F, PHE107F, PHE109E, PHE114E, PHE118E, PHE142E, PHE15F, PHE174F, PHE186E, PHE189F, PHE216E, PHE230F, PHE269F, PHE31F, PHE381E, PHE409E, PHE429E, PHE431E, PHE44F, PHE450F, PHE453E, PHE456E, PHE459E, PHE471F, PHE474F, PHE57F, PHE99F, PRO110F, PRO13F, PRO143E, PRO155E, PRO187F, PRO21E, PRO264F, PRO333E, PRO36F, PRO449E, PRO472F, PRO54E, PRO66F, PRO72F, PRO85E, PRO87F, SER101F, SER112F, SER115F, SER116E, SER117F, SER11F, SER188F, SER190E, SER192E, SER192F, SER218E, SER237E, SER238E, SER254E, SER258E, SER260E, SER2F, SER432F, SER443E, SER446F, SER447E, SER52E, SER67E, SER82E, SER92E, SER92F, THR103E, THR104E, THR111E, THR115E, THR119F, THR140E, THR141F, THR152F, THR215E, THR219E, THR263F, THR405E, THR47F, THR48F, THR58E, THR63F, TRP236E, TRP335E, TRP370F, TRP428F, TRP444E, TRP46F, TRP472E, TYR100E, TYR102F, TYR12F, TYR142F, TYR20E, TYR20F, TYR272F, TYR331E, TYR342E, TYR35F, TYR407E, TYR446E, TYR447F, TYR450E, TYR52F, TYR64E, TYR88F, TYR91E, TYR98F, TYR99E, VAL106E, VAL110E, VAL111F, VAL114F, VAL124E, VAL124F, VAL138E, VAL157F, VAL16E, VAL189E, VAL190F, VAL19E, VAL250E, VAL260F, VAL268E, VAL338E, VAL339E, VAL404E, VAL43F, VAL5F, VAL64F, VAL70E, VAL86E, VAL89F, VAL96F
• E-H: ALA108E, ALA342H, ALA477E, ALA514H, ALA94E, ARG345E, ARG348H, ARG350H, ARG439E, ARG461E, ARG523H, ARG93E, ARG96E, ARG97E, ASN107E, ASN230E, ASN468E, ASN469E, ASN518H, ASN98E, ASP256E, ASP323H, ASP326H, ASP353H, ASP357H, ASP445E, ASP462E, ASP464E, ASP516H, ASP520H, CYS388H, CYS471E, GLN432E, GLN476E, GLN513H, GLN90E, GLU327H, GLU347H, GLU385H, GLU440E, GLU480E, GLY102E, GLY105E, GLY232E, GLY233E, GLY349H, GLY364H, GLY387H, GLY435E, GLY448E, GLY511H, GLY95E, HIS359H, HIS363H, HIS519H, ILE101E, ILE340H, ILE425E, ILE436E, LEU322H, LEU329H, LEU344H, LEU351H, LEU362H, LEU383H, LEU384H, LEU386H, LEU420E, LEU467E, LEU475E, LEU502H, LEU505H, LEU521H, LYS341E, LYS346H, LYS365H, LYS381H, LYS417H, LYS428E, LYS433E, LYS473E, LYS474E, LYS76E, MET330H, MET354H, MET355H, MET434E, MET463E, MET465E, MET512H, PHE328H, PHE429E, PHE431E, PHE438E, PRO339H, PRO341H, PRO414H, PRO437E, PRO449E, PRO470E, PRO478E, SER333H, SER343H, SER358H, SER413H, SER443E, SER447E, SER92E, THR103E, THR104E, THR111E, THR325H, THR345H, THR356H, THR360H, THR466E, THR509H, THR515H, TRP236E, TRP361H, TRP444E, TRP472E, TRP479E, TYR100E, TYR342E, TYR415H, TYR446E, TYR487H, TYR517H, TYR91E, TYR99E, VAL106E, VAL352H, VAL522H
• F-G: ALA108G, ALA342F, ALA477G, ALA514F, ALA94G, ARG345G, ARG348F, ARG350F, ARG439G, ARG461G, ARG523F, ARG93G, ARG96G, ARG97G, ASN107G, ASN230G, ASN468G, ASN469G, ASN518F, ASN98G, ASP256G, ASP323F, ASP326F, ASP353F, ASP357F, ASP445G, ASP462G, ASP464G, ASP516F, ASP520F, CYS388F, CYS471G, GLN432G, GLN476G, GLN513F, GLN90G, GLU327F, GLU347F, GLU385F, GLU440G, GLU480G, GLY102G, GLY105G, GLY232G, GLY233G, GLY349F, GLY364F, GLY387F, GLY435G, GLY448G, GLY511F, GLY95G, HIS359F, HIS363F, HIS519F, ILE101G, ILE340F, ILE425G, ILE436G, LEU322F, LEU329F, LEU344F, LEU351F, LEU362F, LEU383F, LEU384F, LEU386F, LEU420G, LEU467G, LEU475G, LEU502F, LEU505F, LEU521F, LYS341G, LYS346F, LYS365F, LYS381F, LYS417F, LYS428G, LYS433G, LYS473G, LYS474G, LYS76G, MET330F, MET354F, MET355F, MET434G, MET463G, MET465G, MET512F, PHE328F, PHE429G, PHE431G, PHE438G, PRO339F, PRO341F, PRO414F, PRO437G, PRO449G, PRO470G, PRO478G, SER333F, SER343F, SER358F, SER413F, SER443G, SER447G, SER92G, THR103G, THR104G, THR111G, THR325F, THR345F, THR356F, THR360F, THR466G, THR509F, THR515F, TRP236G, TRP324F, TRP361F, TRP444G, TRP472G, TRP479G, TYR100G, TYR342G, TYR415F, TYR446G, TYR487F, TYR517F, TYR91G, TYR99G, VAL106G, VAL352F, VAL522F
• F-H: ALA10F, ALA10H, ALA265F, ALA265H, ALA273F, ALA273H, ALA342F, ALA342H, ALA514F, ALA514H, ARG105F, ARG105H, ARG108F, ARG108H, ARG238F, ARG238H, ARG270F, ARG270H, ARG28F, ARG28H, ARG348F, ARG348H, ARG350F, ARG350H, ARG366F, ARG366H, ARG431F, ARG431H, ARG453F, ARG453H, ARG468F, ARG468H, ARG476F, ARG476H, ARG481F, ARG481H, ARG504F, ARG504H, ARG510F, ARG510H, ARG523F, ARG523H, ASN104F, ASN445F, ASN445H, ASN499F, ASN499H, ASN518F, ASN518H, ASP17F, ASP17H, ASP262F, ASP262H, ASP266F, ASP266H, ASP353F, ASP353H, ASP357F, ASP357H, ASP41F, ASP41H, ASP440F, ASP440H, ASP454F, ASP454H, ASP475F, ASP475H, ASP506F, ASP506H, ASP516F, ASP516H, ASP520F, ASP520H, GLN37F, GLN37H, GLN452F, GLN452H, GLN492F, GLN492H, GLN513F, GLN513H, GLU109F, GLU109H, GLU258F, GLU258H, GLU259F, GLU259H, GLU347F, GLU347H, GLU461F, GLU461H, GLU463F, GLU463H, GLU488F, GLU488H, GLU503F, GLU503H, GLU507F, GLU507H, GLU508F, GLU508H, GLY267F, GLY267H, GLY274F, GLY274H, GLY349F, GLY349H, GLY364F, GLY448F, GLY448H, GLY511F, GLY511H, HIS106F, HIS106H, HIS359F, HIS359H, HIS457F, HIS457H, HIS477F, HIS477H, HIS478F, HIS478H, HIS480F, HIS480H, HIS519F, HIS519H, ILE40F, ILE40H, ILE451F, ILE451H, ILE473F, ILE473H, ILE501F, ILE501H, LEU14F, LEU14H, LEU16F, LEU16H, LEU234F, LEU234H, LEU24F, LEU24H, LEU261F, LEU261H, LEU351F, LEU351H, LEU362F, LEU362H, LEU456F, LEU456H, LEU466F, LEU466H, LEU479F, LEU479H, LEU494F, LEU494H, LEU497F, LEU497H, LEU502F, LEU502H, LEU505F, LEU505H, LEU521F, LEU521H, LYS21H, LYS346F, LYS346H, LYS34F, LYS34H, LYS365F, LYS438F, LYS438H, LYS449F, LYS449H, LYS458F, LYS458H, LYS460F, LYS460H, LYS7F, LYS7H, LYS9F, LYS9H, MET354F, MET354H, MET355F, MET355H, MET491F, MET491H, MET512F, MET512H, PHE107F, PHE107H, PHE15F, PHE15H, PHE435F, PHE435H, PHE44F, PHE44H, PHE450F, PHE450H, PHE474F, PHE474H, PRO110F, PRO110H, PRO13F, PRO13H, PRO257F, PRO257H, PRO264F, PRO264H, PRO465F, PRO465H, PRO472F, PRO472H, SER101F, SER101H, SER11F, SER11H, SER358F, SER358H, SER446F, SER446H, SER482F, SER482H, SER500F, SER500H, THR263F, THR263H, THR345F, THR345H, THR356F, THR356H, THR360F, THR360H, THR455F, THR455H, THR47F, THR47H, THR495F, THR495H, THR496F, THR496H, THR509F, THR509H, THR515F, THR515H, TRP361F, TRP361H, TRP428F, TRP428H, TYR102F, TYR102H, TYR12F, TYR12H, TYR20F, TYR20H, TYR35H, TYR447F, TYR447H, TYR517F, TYR517H, VAL260F, VAL260H, VAL352F, VAL352H, VAL464F, VAL464H, VAL498F, VAL498H, VAL522F, VAL522H
• G-H: ALA108G, ALA10H, ALA122H, ALA123H, ALA132G, ALA140H, ALA155H, ALA217G, ALA235G, ALA24G, ALA251G, ALA25H, ALA265H, ALA337G, ALA340G, ALA457G, ALA460G, ALA477G, ALA61H, ALA63G, ALA65G, ALA67H, ALA69H, ALA94G, ALA97H, ARG100H, ARG105H, ARG108H, ARG187G, ARG210G, ARG239G, ARG248G, ARG25G, ARG270H, ARG28G, ARG28H, ARG431H, ARG453H, ARG461G, ARG481H, ARG59H, ARG60G, ARG93G, ARG96G, ARG97G, ASN104H, ASN107G, ASN113G, ASN130H, ASN137H, ASN145G, ASN230G, ASN397H, ASN445H, ASN56H, ASN65H, ASP116H, ASP117G, ASP121H, ASP122G, ASP133H, ASP136G, ASP17H, ASP19H, ASP222G, ASP22H, ASP234G, ASP256G, ASP262H, ASP266H, ASP27G, ASP29H, ASP38H, ASP403G, ASP41H, ASP426H, ASP445G, ASP454G, ASP454H, ASP462G, ASP6H, ASP77G, CYS113H, CYS138H, CYS153H, CYS154G, CYS249G, CYS471G, CYS62G, CYS70H, CYS88G, CYS95H, GLN119G, GLN129H, GLN136H, GLN18H, GLN191G, GLN252G, GLN268H, GLN37H, GLN3H, GLN432G, GLN45H, GLN476G, GLN4H, GLN53G, GLN53H, GLN58H, GLN71H, GLN90G, GLN93H, GLU109H, GLU120G, GLU120H, GLU137G, GLU139G, GLU153G, GLU156H, GLU184G, GLU18G, GLU22G, GLU243G, GLU244G, GLU259H, GLU261G, GLU263G, GLU32H, GLU334G, GLU336G, GLU33H, GLU380G, GLU408G, GLU410G, GLU411G, GLU427G, GLU42H, GLU440G, GLU480G, GLU51H, GLU54H, GLU60H, GLY102G, GLY105G, GLY127G, GLY134H, GLY147G, GLY157G, GLY159H, GLY160G, GLY185G, GLY188G, GLY191H, GLY232G, GLY233G, GLY246G, GLY255G, GLY257G, GLY267H, GLY30H, GLY406G, GLY424G, GLY424H, GLY435G, GLY448G, GLY448H, GLY452G, GLY455G, GLY55G, GLY61G, GLY66G, GLY69G, GLY74H, GLY84G, GLY87G, GLY89G, GLY91H, GLY94H, GLY95G, HIS106H, HIS193H, HIS396H, HIS429H, HIS442G, HIS451G, HIS457H, HIS477H, HIS478H, HIS480H, HIS80G, HIS90H, ILE101G, ILE123G, ILE135G, ILE147H, ILE148G, ILE156G, ILE158H, ILE159G, ILE197G, ILE225G, ILE231G, ILE240G, ILE259G, ILE262G, ILE40H, ILE425G, ILE430G, ILE436G, ILE451H, ILE458G, ILE59G, ILE79G, ILE81G, ILE8H, LEU131G, LEU134G, LEU135H, LEU141G, LEU144G, LEU14H, LEU158G, LEU16H, LEU17G, LEU193G, LEU241G, LEU242G, LEU247G, LEU24H, LEU261H, LEU264G, LEU427H, LEU475G, LEU55H, LEU56G, LEU62H, LEU73H, LYS121G, LYS129G, LYS130G, LYS132H, LYS133G, LYS139H, LYS143H, LYS146G, LYS176G, LYS21H, LYS23G, LYS26H, LYS27H, LYS330G, LYS341G, LYS34H, LYS39H, LYS414G, LYS426G, LYS428G, LYS433G, LYS449H, LYS474G, LYS50G, LYS51G, LYS68G, LYS68H, LYS76G, LYS7H, LYS9H, MET112G, MET118H, MET131H, MET154H, MET23H, MET271H, MET434G, MET465G, MET57G, MET86H, PHE103H, PHE107H, PHE109G, PHE114G, PHE118G, PHE142G, PHE15H, PHE174H, PHE186G, PHE189H, PHE216G, PHE230H, PHE269H, PHE31H, PHE381G, PHE409G, PHE429G, PHE431G, PHE44H, PHE450H, PHE453G, PHE456G, PHE459G, PHE471H, PHE474H, PHE57H, PHE99H, PRO110H, PRO13H, PRO143G, PRO155G, PRO187H, PRO21G, PRO264H, PRO333G, PRO36H, PRO449G, PRO472H, PRO54G, PRO66H, PRO72H, PRO85G, PRO87H, SER101H, SER112H, SER115H, SER116G, SER117H, SER11H, SER188H, SER190G, SER192G, SER192H, SER218G, SER237G, SER238G, SER254G, SER258G, SER260G, SER2H, SER432H, SER443G, SER446H, SER447G, SER52G, SER67G, SER82G, SER92G, SER92H, THR103G, THR104G, THR111G, THR115G, THR119H, THR140G, THR141H, THR152H, THR215G, THR219G, THR263H, THR405G, THR47H, THR48H, THR58G, THR63H, TRP236G, TRP335G, TRP370H, TRP428H, TRP444G, TRP46H, TRP472G, TYR100G, TYR102H, TYR12H, TYR142H, TYR20G, TYR20H, TYR272H, TYR331G, TYR342G, TYR35H, TYR407G, TYR446G, TYR447H, TYR450G, TYR52H, TYR64G, TYR88H, TYR91G, TYR98H, TYR99G, VAL106G, VAL110G, VAL111H, VAL114H, VAL124G, VAL124H, VAL138G, VAL157H, VAL16G, VAL189G, VAL190H, VAL19G, VAL223G, VAL250G, VAL260H, VAL268G, VAL338G, VAL339G, VAL404G, VAL43H, VAL5H, VAL64H, VAL70G, VAL86G, VAL89H, VAL96H