1LTX

structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-R
  • Int. Res.: 66
  • Norm. En. per Res.: -3.532
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-71.271	-115.4228	-548.442	-735.1358	224	34	2	20417	14	89	84
A-R	-13.0321	-57.6735	-162.404	-233.1096	66	11	0	7061	4	31	10
A-P	0.0	0.0	-10.9639	-10.9639	9	0	1	509	0	0	0
B-R	0.0	0.0	-0.011	-0.011	3	0	0	10	0	2	1
B-P	-11.1825	0.0	-28.9514	-40.1339	33	4	2	1442	0	0	0

Interface residues

• A-B: ALA134B, ALA228A, ALA419A, ALA420A, ALA481A, ALA58A, ALA63A, ALA87B, ARG119A, ARG141A, ARG144B, ARG150A, ARG184A, ARG184B, ARG202A, ARG222B, ARG232B, ARG233A, ARG254B, ARG260B, ARG263A, ARG270A, ARG293A, ARG295A, ARG39A, ARG418A, ARG474A, ARG476A, ARG69A, ARG70A, ASN142A, ASN176B, ASN177A, ASN211B, ASN224A, ASN230B, ASN59A, ASN67A, ASP136B, ASP139A, ASP142B, ASP147A, ASP178B, ASP213B, ASP222A, ASP225A, ASP259B, ASP415A, ASP423A, ASP424A, ASP502A, ASP61A, ASP7B, ASP92B, CYS114A, CYS174B, CYS183B, CYS186A, CYS220B, CYS40B, CYS457A, CYS68A, GLN190A, GLN193B, GLN206B, GLN209B, GLN223B, GLN226A, GLN29A, GLN33A, GLN54A, GLN74A, GLU140A, GLU140B, GLU165B, GLU169B, GLU188B, GLU221B, GLU234B, GLU261B, GLU328B, GLU43B, GLU71A, GLY108A, GLY135B, GLY139B, GLY179B, GLY180B, GLY182B, GLY186B, GLY192B, GLY216B, GLY227B, GLY228B, GLY231B, GLY253B, GLY503A, GLY90B, HIS111A, HIS112A, HIS144A, HIS182A, HIS190B, HIS208B, HIS232A, HIS256B, HIS298A, HIS458A, HIS80B, HIS91B, HIS94B, ILE137B, ILE141B, ILE168B, ILE258B, ILE55A, ILE89B, LEU172B, LEU207B, LEU214B, LEU215B, LEU219B, LEU224B, LEU229B, LEU235A, LEU249B, LEU255B, LEU25A, LEU263B, LEU265A, LEU329B, LEU386A, LEU390A, LEU411A, LEU422A, LEU425A, LEU456A, LEU45B, LEU482A, LEU56A, LEU65A, LEU96B, LYS105A, LYS166B, LYS235B, LYS262B, LYS26A, LYS382A, LYS428A, LYS6B, MET175B, MET271A, MET417A, MET41B, PHE143A, PHE145B, PHE151A, PHE175A, PHE177B, PHE181B, PHE230A, PHE36A, PHE62A, PRO185B, PRO189A, PRO223A, PRO225B, PRO233B, PRO264A, PRO296A, PRO416A, PRO479A, PRO480A, PRO60A, PRO93B, SER106A, SER173B, SER176A, SER179A, SER180A, SER185A, SER187B, SER189B, SER205B, SER212B, SER226B, SER227A, SER297A, SER331B, SER427A, SER42B, SER86B, SER88B, THR266A, THR32A, THR387A, THR454A, THR64A, TRP110A, TRP115A, TRP138B, TRP146A, TRP181A, TRP217B, TRP218B, TRP229A, TRP234A, TRP257B, TRP383A, TRP66A, TYR107A, TYR148A, TYR178A, TYR183A, TYR231A, TYR241B, TYR28A, TYR421A, TYR44B, TYR97B, VAL330B, VAL455A, VAL72A, VAL8B
• A-R: ALA218A, ALA228A, ALA276R, ARG173A, ARG184A, ARG275R, ARG290R, ASN174A, ASN177A, ASN217A, ASN224A, ASN280R, ASN367R, ASN381A, ASP168A, ASP222A, ASP277R, CYS371A, GLN216A, GLN375A, GLU213A, GLU288R, GLU367A, GLU369A, GLU373A, GLU376A, GLU378A, GLU380A, ILE171A, LEU212A, LEU214A, LEU284R, LEU292R, LEU326R, LEU374A, LEU377A, LYS282R, LYS289R, LYS294R, LYS325R, MET286R, MET291R, MET293R, PHE175A, PHE219A, PHE220A, PHE279R, PHE295R, PRO223A, PRO379A, SER169A, SER274R, SER281R, SER366A, SER370A, THR167A, THR172A, THR221A, THR285R, THR297R, THR327R, TRP181A, TRP229A, VAL215A, VAL278R, VAL287R
• A-P: ALA10P, ALA11P, ALA12P, ASP61A, HIS144A, LYS105A, PHE143A, SER106A, TYR107A
• B-R: ARG290R, LYS6B, THR297R
• B-P: ALA10P, ALA11P, ALA12P, ALA191B, ALA279B, ALA9P, ARG144B, ARG232B, ASP238B, ASP280B, ASP287B, CYS183B, CYS240B, GLN193B, GLY192B, GLY231B, GLY49B, HIS190B, HIS290B, LEU45B, MET285B, PHE289B, PHE293B, PRO288B, SER42B, SER48B, THR291B, TRP244B, TRP52B, TYR241B, TYR30B, TYR44B, VAL286B