1LTO

human alpha1-tryptase

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 53
  • Norm. En. per Res.: -4.0152
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.3328	-59.0428	-112.55	-183.9256	52	5	1	4636	4	13	11
A-D	-52.9488	0.0	-235.893	-288.8418	89	12	11	9248	0	10	4
B-C	-32.1674	0.0	-219.555	-251.7224	88	9	13	8938	1	10	4
C-D	-7.1374	-84.3926	-121.276	-212.806	53	7	1	4673	5	13	11

Interface residues

• A-B: ARG24A, ARG24B, ARG34A, ARG34B, ARG36A, ARG36B, ARG37A, ARG37B, ASN146B, ASP145A, ASP145B, ASP147A, ASP147B, ASP37A, ASP37B, ASP80A, ASP80B, GLN71A, GLN71B, GLN79A, GLN79B, GLU149A, GLU149B, GLU70A, GLU70B, HIS40A, HIS40B, HIS72A, HIS72B, LEU151A, LEU151B, LEU73A, LEU73B, MET39A, MET39B, PHE153A, PHE153B, PRO150A, PRO150B, PRO152A, PRO152B, PRO154A, TRP38A, TRP38B, TYR37A, TYR37B, TYR74A, TYR74B, TYR75A, TYR75B, VAL144A, VAL144B
• A-D: ALA101A, ALA101D, ALA104A, ALA104D, ALA173A, ALA173D, ALA56A, ALA56D, ARG174A, ARG174D, ARG177A, ARG177D, ARG224A, ARG224D, ARG87D, ASP173A, ASP173D, ASP60A, ASP60D, CYS58A, CYS58D, GLN221A, GLN221D, GLN93A, GLN93D, GLN98A, GLN98D, GLY100D, GLY173A, GLY173D, GLY60A, GLY60D, HIS173A, HIS173D, HIS57A, HIS57D, HIS91A, HIS91D, ILE175A, ILE175D, ILE176A, ILE176D, ILE227A, ILE227D, ILE88A, ILE88D, ILE89A, ILE89D, ILE96A, ILE96D, ILE97A, ILE97D, LEU106D, LEU173A, LEU173D, LEU59A, LEU59D, LEU61A, LEU61D, LEU64A, LEU64D, LYS60A, LYS60D, MET180A, MET180D, PHE94A, PHE94D, PRO60A, PRO60D, PRO92A, PRO92D, THR173A, THR173D, THR99A, THR99D, TRP215A, TRP215D, TYR172A, TYR172D, TYR173A, TYR173D, TYR95A, TYR95D, VAL173A, VAL173D, VAL60A, VAL60D, VAL90A, VAL90D
• B-C: ALA101B, ALA101C, ALA173B, ALA173C, ALA56B, ALA56C, ARG174B, ARG174C, ARG177B, ARG177C, ARG224B, ARG224C, ARG87B, ASP169B, ASP173B, ASP173C, ASP60B, ASP60C, CYS58B, CYS58C, GLN221B, GLN221C, GLN93B, GLN93C, GLN98B, GLN98C, GLY100B, GLY173B, GLY173C, GLY60B, GLY60C, HIS173B, HIS173C, HIS57B, HIS57C, HIS91B, HIS91C, ILE175B, ILE175C, ILE176B, ILE176C, ILE227B, ILE227C, ILE88B, ILE88C, ILE89B, ILE89C, ILE96B, ILE96C, ILE97B, ILE97C, LEU106C, LEU173B, LEU173C, LEU59B, LEU59C, LEU61B, LEU61C, LEU64B, LEU64C, LYS60B, LYS60C, MET180B, MET180C, PHE94B, PHE94C, PRO60B, PRO60C, PRO92B, PRO92C, THR173B, THR173C, THR99B, THR99C, TRP215B, TRP215C, TYR172B, TYR172C, TYR173B, TYR173C, TYR95B, TYR95C, VAL173B, VAL173C, VAL60B, VAL60C, VAL90B, VAL90C
• C-D: ARG24C, ARG24D, ARG34C, ARG34D, ARG36C, ARG36D, ARG37C, ARG37D, ASN146C, ASP145C, ASP145D, ASP147C, ASP147D, ASP37C, ASP37D, ASP80C, ASP80D, GLN71C, GLN71D, GLN79C, GLN79D, GLU149C, GLU149D, GLU70C, GLU70D, HIS40C, HIS40D, HIS72C, HIS72D, LEU151C, LEU151D, LEU73C, LEU73D, MET39C, MET39D, PHE153C, PHE153D, PRO150C, PRO150D, PRO152C, PRO152D, PRO154C, PRO154D, TRP38C, TRP38D, TYR37C, TYR37D, TYR74C, TYR74D, TYR75C, TYR75D, VAL144C, VAL144D