1LQB

crystal structure of a hydroxylated hif-1 alpha peptide bound to the pvhl/elongin-c/elongin-b complex

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 64
  • Norm. En. per Res.: -6.3852
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-96.7211	-19.8742	-350.696	-467.2913	97	24	6	13241	2	25	25
A-C	0.0	0.0	-42.0583	-42.0583	21	0	2	2054	0	5	6
A-D	0.0	0.0	-0.0031	-0.0031	2	0	0	1	0	0	0
B-C	-57.333	-69.1832	-279.365	-405.8812	88	16	15	12175	4	11	12
B-D	0.0	0.0	-6.2856	-6.2856	5	0	0	140	0	1	0
C-D	-77.618	-67.9941	-263.039	-408.6511	64	17	2	8772	3	11	2

Interface residues

• A-B: ALA100B, ALA18A, ALA71A, ALA73A, ALA96B, ARG63B, ARG68A, ARG82B, ARG8A, ARG9A, ASP17A, ASP25B, ASP2A, CYS74B, GLN70A, GLU102B, GLU28B, GLU89B, GLU91A, GLU92B, GLU98A, GLU98B, GLY26B, GLY33A, HIS10A, HIS27B, HIS35B, HIS68B, ILE14A, ILE22B, ILE30A, ILE30B, ILE34A, ILE65B, ILE7A, ILE90A, ILE90B, ILE99B, LEU101B, LEU103B, LEU21B, LEU35A, LEU5A, LEU70B, LEU99A, LYS104A, LYS11A, LYS20B, LYS32B, LYS72B, LYS80B, MET103A, MET17B, MET1A, MET6A, MET75B, PHE15A, PHE29B, PHE4A, PHE77B, PHE93A, PHE93B, PRO100A, PRO66B, PRO69A, PRO72A, PRO91B, PRO92A, PRO94B, PRO96A, PRO97A, PRO97B, SER23B, SER24B, SER64A, SER67B, SER71B, SER94A, SER95A, THR12A, THR13A, THR16A, THR74A, THR78B, THR88B, TYR18B, TYR76B, TYR79B, TYR83B, VAL102A, VAL19B, VAL31A, VAL31B, VAL3A, VAL69B, VAL73B, VAL81B
• A-C: ARG167C, ARG176C, ARG177C, ASN174C, ASP101A, ASP179C, GLU173C, ILE180C, LEU169C, LEU178C, LEU99A, LYS104A, LYS171C, MET103A, PRO100A, SER168C, TYR175C, VAL102A, VAL165C, VAL166C, VAL170C
• A-D: GLN65A, SER576D
• B-C: ALA100B, ALA106B, ALA107B, ALA96B, ARG161C, ARG167C, ARG177C, ARG79C, ARG82B, ARG82C, ASN108B, ASN131C, ASN150C, ASN78C, ASN85B, ASP111B, ASP121C, ASP126C, ASP179C, ASP187C, CYS112B, CYS162C, CYS74B, GLN132C, GLN164C, GLU102B, GLU160C, GLU89B, GLU92B, GLU98B, GLY104C, ILE151C, ILE180C, ILE90B, ILE95B, ILE99B, LEU101B, LEU103B, LEU104B, LEU110B, LEU128C, LEU129C, LEU153C, LEU158C, LEU163C, LEU169C, LEU178C, LEU184C, LEU188C, LEU70B, LYS159C, LYS72B, LYS80B, MET105B, MET75B, PHE109B, PHE77B, PHE93B, PRO154C, PRO81C, PRO91B, PRO94B, PRO97B, SER168C, SER183C, SER39B, SER80C, SER86B, SER87B, THR152C, THR157C, THR38B, THR84B, THR88B, TYR156C, TYR175C, TYR185C, TYR76B, TYR79B, TYR83B, VAL155C, VAL165C, VAL166C, VAL170C, VAL181C, VAL69B, VAL73B, VAL81B
• B-D: GLU89B, LEU574D, PHE577D, PRO91B, SER576D
• C-D: ALA149C, ALA563D, ARG107C, ARG108C, ARG575D, ARG64C, ARG69C, ARG79C, ARG82C, ASN150C, ASN67C, ASN78C, ASN90C, ASP569D, ASP570D, ASP571D, ASP92C, CYS77C, GLN573D, GLN73C, GLN96C, GLU560D, GLU70C, GLY104C, GLY106C, HIS110C, HIS115C, ILE109C, ILE151C, ILE566D, ILE75C, LEU101C, LEU562D, LEU574D, MET561D, MET568D, PHE148C, PHE572D, PHE577D, PHE76C, PHE91C, PRO102C, PRO103C, PRO567D, PRO71C, PRO81C, PRO86C, PRO99C, SER111C, SER576D, SER65C, SER68C, SER72C, SER80C, THR100C, THR105C, THR152C, TRP117C, TRP88C, TYR112C, TYR565D, TYR98C, VAL66C, VAL74C