1LFD

crystal structure of the active ras protein complexed with the ras-interacting domain of ralgds

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 62
  • Norm. En. per Res.: -5.5087
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-65.4143	-59.3868	-169.001	-293.8021	61	3	3	6124	3	25	14
A-C	-40.1067	6.1985	-60.259	-94.1672	33	4	0	2510	0	2	3
A-D	-17.8315	9.2945	-72.5827	-81.1198	41	4	0	3280	0	25	19
B-C	-22.4586	7.6638	-66.94	-81.7349	43	2	0	2981	0	25	24
B-D	0.0	21.9241	-77.4261	-55.502	52	6	0	3117	0	16	19
C-D	-67.3197	-80.7967	-193.421	-341.5375	62	7	3	6577	6	28	15

Interface residues

• A-B: ALA259B, ALA266B, ARG20A, ARG241B, ASN27A, ASN29A, ASN54A, ASP233B, ASP238B, ASP254B, ASP257B, ASP26A, ASP51A, ASP56A, CYS16A, CYS17A, GLN225B, GLN243B, GLN261B, GLN270B, GLU237B, GLU263B, GLY28A, HIS227B, HIS53A, ILE18A, ILE19A, ILE221B, ILE224B, ILE236B, ILE255B, ILE34A, LEU23A, LEU252B, LEU253B, LEU256B, LEU35A, LEU55A, LYS231B, LYS242B, LYS32A, LYS48A, LYS52A, MET267B, MET30A, MET50A, PRO234B, SER217B, SER239B, SER33A, THR220B, THR235B, TYR232B, TYR240B, TYR264B, TYR271B, TYR31A, VAL21A, VAL229B, VAL25A, VAL36A
• A-C: ARG20A, ARG20C, ASP15A, ASP15A9, ASP15C, CB7.8964724.79402, CYS16A, CYS16C, CYS17A, CYS17C, GLN39A, GLY14A, GLY14C, ILE18A, ILE18C, ILE19A, ILE19C, LEU35A, LEU35C, LYS48C, MET87A, PHE84A, PHE84C, SER38A, SER38C, SER89A, SER89C, THR37A, THR37C, TYR93A, TYR93C, VAL36A, VAL36C
• A-D: ALA266D, ALA49A, ARG268D, ARG273D, ARG47A, ASN54A, ASP15A, ASP269D, ASP292D, ASP40A, ASP51A, ASP56A, CYS16A, GLN261D, GLN270D, GLN295D, GLN299D, GLN39A, GLU262D, GLU263D, GLU291D, GLY14A, ILE18A, ILE19A, ILE236D, ILE34A, LEU35A, LYS288D, LYS41A, LYS48A, LYS52A, MET267D, SER265D, SER33A, SER38A, THR37A, THR44A, TYR264D, TYR271D, VAL36A, VAL45A
• B-C: ALA266B, ALA49C, ARG268B, ARG273B, ARG47C, ASN54C, ASP269B, ASP292B, ASP40C, ASP51C, ASP56C, CYS16C, GLN261B, GLN270B, GLN295B, GLN39C, GLU262B, GLU263B, GLU291B, GLU57C, GLU59C, GLY14C, ILE18C, ILE19C, ILE236B, ILE34C, ILE46C, LEU35C, LYS288B, LYS41C, LYS48C, LYS52C, MET267B, MET50C, PRO43C, SER265B, SER33C, SER38C, THR37C, THR44C, TYR264B, VAL36C, VAL45C
• B-D: ALA211B, ALA211D, ALA259B, ALA259D, ASN285B, ASN285D, ASN286B, ASN286D, ASP230B, ASP230D, ASP233B, ASP233D, GLN261B, GLN261D, GLU262B, GLU262D, GLU263B, GLU263D, GLY212B, GLY212D, GLY213B, GLY213D, GLY215B, GLY215D, GLY260B, GLY260D, ILE236B, ILE236D, LYS216B, LYS216D, LYS231B, LYS231D, LYS288B, LYS288D, LYS317B, LYS317D, PRO234B, PRO234D, SER217B, SER217D, SER289B, SER289D, THR235B, THR235D, TYR232B, TYR232D, TYR264B, TYR264D, VAL214B, VAL214D, VAL229B, VAL229D
• C-D: ALA259D, ALA49C, ARG20C, ARG241D, ARG47C, ASN27C, ASN29C, ASN54C, ASP230D, ASP233D, ASP238D, ASP254D, ASP257D, ASP26C, ASP51C, ASP56C, CYS16C, CYS17C, GLN225D, GLN243D, GLN261D, GLN270D, GLU237D, GLU263D, GLY28C, HIS227D, HIS53C, ILE18C, ILE19C, ILE221D, ILE224D, ILE236D, ILE255D, ILE34C, LEU23C, LEU252D, LEU253D, LEU256D, LEU35C, LEU55C, LYS231D, LYS242D, LYS32C, LYS48C, LYS52C, MET267D, MET30C, MET50C, PHE228D, PRO234D, SER217D, SER239D, SER33C, THR220D, THR235D, TYR232D, TYR240D, TYR264D, TYR31C, VAL21C, VAL229D, VAL36C