1L8H

dna protection and binding by e. coli dps protein

• Total interactions analyzed: 66
• Total true interactions: 30
• Strongest Interaction:
  • Chains: A-I
  • Int. Res.: 72
  • Norm. En. per Res.: -5.6729
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-65.2946	-17.0632	-337.307	-419.6647	142	22	6	16094	0	12	16
A-E	-74.9465	-111.403	-206.9	-393.2495	72	11	0	7497	8	37	41
A-H	-17.735	-15.0831	-108.014	-140.8321	42	3	5	4262	0	11	8
A-I	-87.3568	-112.0464	-209.043	-408.4462	72	13	0	7553	8	37	43
A-J	-19.3586	-15.3287	-115.016	-149.7033	43	3	5	4352	0	11	8
B-E	-17.6391	-15.3425	-113.328	-146.3097	43	3	5	4312	0	11	8
B-H	-75.6564	-110.3871	-206.399	-392.4426	72	11	0	7376	8	37	42
B-K	-73.1917	-111.6009	-208.08	-392.8726	72	10	0	7498	8	37	43
B-L	-15.9921	-15.6261	-110.374	-141.9922	42	3	5	4303	0	11	8
C-D	-63.765	-14.6725	-339.298	-417.7356	143	29	6	16241	0	14	18
C-F	-76.8847	-112.3625	-206.751	-395.9982	73	10	0	7399	8	39	42
C-G	-16.8076	-15.2008	-111.381	-143.3894	43	2	5	4281	0	11	8
C-K	-16.3013	-15.3889	-114.388	-146.0783	43	2	5	4330	0	11	8
C-L	-69.2533	-110.3032	-201.183	-380.7395	71	10	0	7318	8	37	40
D-F	-16.6035	-15.4703	-116.993	-149.0669	42	3	5	4345	0	11	8
D-G	-74.7298	-109.5156	-202.786	-387.0314	72	10	0	7377	8	37	41
D-I	-15.099	-15.3345	-111.974	-142.4075	42	1	5	4275	0	11	8
D-J	-74.5118	-109.9457	-213.967	-398.4245	71	12	0	7576	8	37	43
E-F	-68.1718	-17.4747	-330.933	-416.5795	141	34	6	16349	0	12	16
E-I	-81.5658	-107.5915	-206.667	-395.8243	72	11	0	7555	8	37	43
E-L	-15.9307	-15.0811	-113.366	-144.3778	42	3	5	4316	0	11	8
F-I	-14.5675	-16.0126	-114.867	-145.4471	43	3	5	4346	0	11	8
F-L	-70.9975	-112.535	-206.881	-390.4135	71	12	0	7416	8	37	43
G-H	-68.9914	-16.9706	-342.99	-428.952	141	22	6	16070	0	12	16
G-J	-78.2436	-112.3908	-206.471	-397.1053	72	13	0	7459	8	37	43
G-K	-15.9857	-15.8215	-117.713	-149.5202	43	2	5	4323	0	11	8
H-J	-16.3321	-14.8769	-112.234	-143.443	42	4	5	4282	0	11	8
H-K	-66.1858	-112.4609	-206.582	-385.2287	72	12	0	7438	8	37	42
I-J	-71.7565	-16.993	-340.914	-429.6635	144	30	6	16326	0	12	17
K-L	-66.0071	-17.297	-340.357	-423.6611	141	34	6	16416	0	12	16

Interface residues

• A-B: ALA50A, ALA50B, ALA78A, ALA78B, ALA81A, ALA81B, ALA84A, ALA84B, ALA91A, ALA91B, ARG124A, ARG124B, ARG18A, ARG18B, ARG55A, ARG55B, ARG70A, ARG70B, ARG83A, ARG83B, ASN13A, ASN19A, ASN19B, ASN34A, ASN34B, ASN53A, ASN53B, ASN99A, ASN99B, ASP110A, ASP110B, ASP42A, ASP42B, ASP67A, ASP67B, CYS75A, CYS75B, GLN49A, GLN49B, GLN86A, GLN86B, GLN96A, GLN96B, GLU82A, GLU82B, GLY88A, GLY88B, GLY89A, GLY89B, GLY93A, GLY93B, HIS112A, HIS112B, HIS117A, HIS117B, HIS51A, HIS51B, HIS63A, HIS63B, HIS76A, HIS76B, ILE111A, ILE111B, ILE38A, ILE38B, ILE41A, ILE41B, ILE46A, ILE46B, ILE74A, ILE74B, ILE98A, ILE98B, LEU104A, LEU104B, LEU109A, LEU109B, LEU14A, LEU14B, LEU15A, LEU15B, LEU43A, LEU43B, LEU45A, LEU45B, LEU77A, LEU77B, LEU87A, LEU87B, LEU92A, LEU92B, LYS101A, LYS101B, LYS105A, LYS105B, LYS26A, LYS26B, LYS48A, LYS48B, MET54A, MET54B, MET80A, MET80B, PHE59A, PHE59B, PRO108A, PRO108B, SER100A, SER100B, SER106A, SER106B, SER44A, SER44B, THR102A, THR102B, THR12A, THR17A, THR17B, THR47A, THR47B, THR71A, THR71B, THR79A, THR79B, THR94A, THR94B, THR95A, THR95B, TRP52A, TRP52B, TYR107A, TYR107B, TYR16A, TYR16B, VAL37A, VAL37B, VAL85A, VAL85B, VAL90A, VAL90B, VAL97A, VAL97B
• A-E: ALA122E, ALA126E, ALA129E, ALA135E, ALA145A, ALA145E, ALA150A, ALA150E, ALA151A, ALA151E, ALA78A, ALA81A, ARG124E, ARG133E, ARG153E, ARG18A, ARG83A, ASN130E, ASN19A, ASP123E, ASP131E, ASP141A, ASP142A, ASP143A, ASP146A, ASP146E, ASP154E, ASP156E, ASP20A, GLN115E, GLN86A, GLU120E, GLU163E, GLU25A, GLU82A, GLY137E, GLY88A, HIS76A, ILE127E, ILE136E, ILE147A, ILE162E, ILE166E, LEU118E, LEU121E, LEU148A, LEU148E, LEU155E, LEU159E, LEU15A, LEU87A, LYS119E, LYS134E, LYS157E, LYS26A, MET80A, PHE158E, PHE161E, SER152E, SER164E, SER22A, THR144A, THR149A, THR149E, THR17A, THR79A, TRP160E, TYR125E, TYR16A, VAL132E, VAL21A, VAL85A
• A-H: ALA57A, ALA57H, ALA61A, ALA61H, ARG55A, ASN113A, ASN165H, ASN53A, ASN58A, ASN58H, GLN115H, GLU163H, GLU167A, GLU167H, GLU64A, GLU64H, GLY56A, HIS51A, HIS63A, HIS63H, ILE162H, ILE166H, ILE60A, ILE60H, LEU118H, LEU159H, LEU66H, LYS157H, MET54A, MET65H, PHE158H, PHE161H, PHE59A, PHE59H, PHE69H, SER164H, TRP160H, TRP52A, VAL114A, VAL114H, VAL62A, VAL62H
• A-I: ALA122A, ALA126A, ALA129A, ALA135A, ALA145A, ALA145I, ALA150A, ALA150I, ALA151A, ALA151I, ALA78I, ALA81I, ARG124A, ARG133A, ARG153A, ARG18I, ARG83I, ASN130A, ASN19I, ASP123A, ASP131A, ASP141I, ASP142I, ASP143I, ASP146A, ASP146I, ASP154A, ASP156A, ASP20I, GLN115A, GLN86I, GLU120A, GLU163A, GLU25I, GLU82I, GLY137A, GLY88I, HIS76I, ILE127A, ILE136A, ILE147I, ILE162A, ILE166A, LEU118A, LEU121A, LEU148A, LEU148I, LEU155A, LEU159A, LEU15I, LEU87I, LYS119A, LYS134A, LYS157A, LYS26I, MET80I, PHE158A, PHE161A, SER152A, SER164A, SER22I, THR144I, THR149A, THR149I, THR17I, THR79I, TRP160A, TYR125A, TYR16I, VAL132A, VAL21I, VAL85I
• A-J: ALA50J, ALA57A, ALA57J, ALA61A, ALA61J, ARG55J, ASN113J, ASN165A, ASN53J, ASN58A, ASN58J, GLN115A, GLU163A, GLU167A, GLU167J, GLU64A, GLU64J, GLY56J, HIS51J, HIS63A, HIS63J, ILE162A, ILE166A, ILE60A, ILE60J, LEU118A, LEU159A, LEU66A, LYS157A, MET54J, MET65A, PHE158A, PHE161A, PHE59A, PHE59J, PHE69A, SER164A, TRP160A, TRP52J, VAL114A, VAL114J, VAL62A, VAL62J
• B-E: ALA50B, ALA57B, ALA57E, ALA61B, ALA61E, ARG55B, ASN113B, ASN165E, ASN53B, ASN58B, ASN58E, GLN115E, GLU163E, GLU167B, GLU167E, GLU64B, GLU64E, GLY56B, HIS51B, HIS63B, HIS63E, ILE162E, ILE166E, ILE60B, ILE60E, LEU118E, LEU159E, LEU66E, LYS157E, MET54B, MET65E, PHE158E, PHE161E, PHE59B, PHE59E, PHE69E, SER164E, TRP160E, TRP52B, VAL114B, VAL114E, VAL62B, VAL62E
• B-H: ALA122H, ALA126H, ALA129H, ALA135H, ALA145B, ALA145H, ALA150B, ALA150H, ALA151B, ALA151H, ALA78B, ALA81B, ARG124H, ARG133H, ARG153H, ARG18B, ARG83B, ASN130H, ASN19B, ASP123H, ASP131H, ASP141B, ASP142B, ASP143B, ASP146B, ASP146H, ASP154H, ASP156H, ASP20B, GLN115H, GLN86B, GLU120H, GLU163H, GLU25B, GLU82B, GLY137H, GLY88B, HIS76B, ILE127H, ILE136H, ILE147B, ILE162H, ILE166H, LEU118H, LEU121H, LEU148B, LEU148H, LEU155H, LEU159H, LEU15B, LEU87B, LYS119H, LYS134H, LYS157H, LYS26B, MET80B, PHE158H, PHE161H, SER152H, SER164H, SER22B, THR144B, THR149B, THR149H, THR17B, THR79B, TRP160H, TYR125H, TYR16B, VAL132H, VAL21B, VAL85B
• B-K: ALA122B, ALA126B, ALA129B, ALA145B, ALA145K, ALA150B, ALA150K, ALA151B, ALA151K, ALA78K, ALA81K, ARG124B, ARG133B, ARG153B, ARG18K, ARG83K, ASN130B, ASN19K, ASP123B, ASP131B, ASP141K, ASP142K, ASP143K, ASP146B, ASP146K, ASP154B, ASP156B, ASP20K, GLN115B, GLN86K, GLU120B, GLU163B, GLU25K, GLU82K, GLY137B, GLY88K, HIS76K, ILE127B, ILE136B, ILE147K, ILE162B, ILE166B, LEU118B, LEU121B, LEU148B, LEU148K, LEU155B, LEU159B, LEU15K, LEU87K, LYS105B, LYS119B, LYS134B, LYS157B, LYS26K, MET80K, PHE158B, PHE161B, SER152B, SER164B, SER22K, THR144K, THR149B, THR149K, THR17K, THR79K, TRP160B, TYR125B, TYR16K, VAL132B, VAL21K, VAL85K
• B-L: ALA57B, ALA57L, ALA61B, ALA61L, ARG55L, ASN113L, ASN165B, ASN53L, ASN58B, ASN58L, GLN115B, GLU163B, GLU167B, GLU167L, GLU64B, GLU64L, GLY56L, HIS51L, HIS63B, HIS63L, ILE162B, ILE166B, ILE60B, ILE60L, LEU118B, LEU159B, LEU66B, LYS157B, MET54L, MET65B, PHE158B, PHE161B, PHE59B, PHE59L, PHE69B, SER164B, TRP160B, TRP52L, VAL114B, VAL114L, VAL62B, VAL62L
• C-D: ALA50C, ALA50D, ALA78C, ALA78D, ALA81C, ALA81D, ALA84C, ALA84D, ALA91C, ALA91D, ARG124C, ARG124D, ARG18C, ARG18D, ARG55C, ARG55D, ARG70C, ARG70D, ARG83C, ARG83D, ASN113D, ASN13C, ASN13D, ASN19C, ASN34C, ASN34D, ASN53C, ASN53D, ASN99C, ASN99D, ASP110C, ASP110D, ASP42C, ASP42D, ASP67C, ASP67D, CYS75C, CYS75D, GLN49C, GLN49D, GLN86C, GLN86D, GLN96C, GLN96D, GLU82C, GLU82D, GLY88C, GLY88D, GLY89C, GLY89D, GLY93C, GLY93D, HIS112C, HIS112D, HIS117C, HIS117D, HIS51C, HIS51D, HIS63C, HIS63D, HIS76C, HIS76D, ILE111C, ILE111D, ILE38C, ILE38D, ILE41C, ILE41D, ILE46C, ILE46D, ILE74C, ILE74D, ILE98C, ILE98D, LEU104C, LEU104D, LEU109C, LEU109D, LEU14C, LEU14D, LEU15C, LEU15D, LEU43C, LEU43D, LEU45C, LEU45D, LEU77C, LEU77D, LEU87C, LEU87D, LEU92C, LEU92D, LYS101C, LYS101D, LYS105C, LYS105D, LYS10C, LYS26C, LYS26D, LYS48C, LYS48D, MET54C, MET54D, MET80C, MET80D, PHE59C, PHE59D, PRO108C, PRO108D, SER100C, SER100D, SER106C, SER106D, SER44C, SER44D, THR102C, THR102D, THR17C, THR17D, THR47C, THR47D, THR71C, THR71D, THR79C, THR79D, THR94C, THR94D, THR95C, THR95D, TRP52C, TRP52D, TYR107C, TYR107D, TYR16C, TYR16D, VAL37C, VAL37D, VAL85C, VAL85D, VAL90C, VAL90D, VAL97C, VAL97D
• C-F: ALA122F, ALA126F, ALA129F, ALA145C, ALA145F, ALA150C, ALA150F, ALA151C, ALA151F, ALA78C, ALA81C, ARG124F, ARG133F, ARG153F, ARG18C, ARG83C, ASN130F, ASN19C, ASP123F, ASP131F, ASP141C, ASP142C, ASP143C, ASP146C, ASP146F, ASP154F, ASP156F, ASP20C, GLN115F, GLN86C, GLU120F, GLU163F, GLU167F, GLU25C, GLU82C, GLY137F, GLY88C, HIS76C, ILE127F, ILE136F, ILE147C, ILE162F, ILE166F, LEU118F, LEU121F, LEU148C, LEU148F, LEU155F, LEU159F, LEU15C, LEU87C, LYS10C, LYS119F, LYS134F, LYS157F, LYS26C, MET80C, PHE158F, PHE161F, SER152F, SER164F, SER22C, THR144C, THR149C, THR149F, THR17C, THR79C, TRP160F, TYR125F, TYR16C, VAL132F, VAL21C, VAL85C
• C-G: ALA50C, ALA57C, ALA57G, ALA61C, ALA61G, ARG55C, ASN113C, ASN165G, ASN53C, ASN58C, ASN58G, GLN115G, GLU163G, GLU167C, GLU167G, GLU64C, GLU64G, GLY56C, HIS51C, HIS63C, HIS63G, ILE162G, ILE166G, ILE60C, ILE60G, LEU118G, LEU159G, LEU66G, LYS157G, MET54C, MET65G, PHE158G, PHE161G, PHE59C, PHE59G, PHE69G, SER164G, TRP160G, TRP52C, VAL114C, VAL114G, VAL62C, VAL62G
• C-K: ALA50K, ALA57C, ALA57K, ALA61C, ALA61K, ARG55K, ASN113K, ASN165C, ASN53K, ASN58C, ASN58K, GLN115C, GLU163C, GLU167C, GLU167K, GLU64C, GLU64K, GLY56K, HIS51K, HIS63C, HIS63K, ILE162C, ILE166C, ILE60C, ILE60K, LEU118C, LEU159C, LEU66C, LYS157C, MET54K, MET65C, PHE158C, PHE161C, PHE59C, PHE59K, PHE69C, SER164C, TRP160C, TRP52K, VAL114C, VAL114K, VAL62C, VAL62K
• C-L: ALA122C, ALA126C, ALA129C, ALA145C, ALA145L, ALA150C, ALA150L, ALA151C, ALA151L, ALA78L, ALA81L, ARG124C, ARG133C, ARG153C, ARG18L, ARG83L, ASN130C, ASN19L, ASP123C, ASP131C, ASP141L, ASP142L, ASP143L, ASP146C, ASP146L, ASP154C, ASP156C, ASP20L, GLN115C, GLN86L, GLU120C, GLU163C, GLU25L, GLU82L, GLY137C, GLY88L, HIS76L, ILE127C, ILE136C, ILE147L, ILE162C, ILE166C, LEU118C, LEU121C, LEU148C, LEU148L, LEU155C, LEU159C, LEU15L, LEU87L, LYS119C, LYS134C, LYS157C, LYS26L, MET80L, PHE158C, PHE161C, SER152C, SER164C, SER22L, THR144L, THR149C, THR149L, THR17L, THR79L, TRP160C, TYR125C, TYR16L, VAL132C, VAL21L, VAL85L
• D-F: ALA57D, ALA57F, ALA61D, ALA61F, ARG55D, ASN113D, ASN165F, ASN53D, ASN58D, ASN58F, GLN115F, GLU163F, GLU167D, GLU167F, GLU64D, GLU64F, GLY56D, HIS51D, HIS63D, HIS63F, ILE162F, ILE166F, ILE60D, ILE60F, LEU118F, LEU159F, LEU66F, LYS157F, MET54D, MET65F, PHE158F, PHE161F, PHE59D, PHE59F, PHE69F, SER164F, TRP160F, TRP52D, VAL114D, VAL114F, VAL62D, VAL62F
• D-G: ALA122G, ALA126G, ALA129G, ALA135G, ALA145D, ALA145G, ALA150D, ALA150G, ALA151D, ALA151G, ALA78D, ALA81D, ARG124G, ARG133G, ARG153G, ARG18D, ARG83D, ASN130G, ASN19D, ASP123G, ASP131G, ASP141D, ASP142D, ASP143D, ASP146D, ASP146G, ASP154G, ASP156G, ASP20D, GLN115G, GLN86D, GLU120G, GLU163G, GLU25D, GLU82D, GLY137G, GLY88D, HIS76D, ILE127G, ILE136G, ILE147D, ILE162G, ILE166G, LEU118G, LEU121G, LEU148D, LEU148G, LEU155G, LEU159G, LEU15D, LEU87D, LYS119G, LYS134G, LYS157G, LYS26D, MET80D, PHE158G, PHE161G, SER152G, SER164G, SER22D, THR144D, THR149D, THR149G, THR17D, THR79D, TRP160G, TYR125G, TYR16D, VAL132G, VAL21D, VAL85D
• D-I: ALA57D, ALA57I, ALA61D, ALA61I, ARG55I, ASN113I, ASN165D, ASN53I, ASN58D, ASN58I, GLN115D, GLU163D, GLU167D, GLU167I, GLU64D, GLU64I, GLY56I, HIS51I, HIS63D, HIS63I, ILE162D, ILE166D, ILE60D, ILE60I, LEU118D, LEU159D, LEU66D, LYS157D, MET54I, MET65D, PHE158D, PHE161D, PHE59D, PHE59I, PHE69D, SER164D, TRP160D, TRP52I, VAL114D, VAL114I, VAL62D, VAL62I
• D-J: ALA122D, ALA126D, ALA129D, ALA145D, ALA145J, ALA150D, ALA150J, ALA151D, ALA151J, ALA78J, ALA81J, ARG124D, ARG133D, ARG153D, ARG18J, ARG83J, ASN130D, ASN19J, ASP123D, ASP131D, ASP141J, ASP142J, ASP143J, ASP146D, ASP146J, ASP154D, ASP156D, ASP20J, GLN115D, GLN86J, GLU120D, GLU163D, GLU25J, GLU82J, GLY137D, GLY88J, HIS76J, ILE127D, ILE136D, ILE147J, ILE162D, ILE166D, LEU118D, LEU121D, LEU148D, LEU148J, LEU155D, LEU159D, LEU15J, LEU87J, LYS119D, LYS134D, LYS157D, LYS26J, MET80J, PHE158D, PHE161D, SER152D, SER164D, SER22J, THR144J, THR149D, THR149J, THR17J, THR79J, TRP160D, TYR125D, TYR16J, VAL132D, VAL21J, VAL85J
• E-F: ALA50E, ALA50F, ALA78E, ALA78F, ALA81E, ALA81F, ALA84E, ALA84F, ALA91E, ALA91F, ARG124E, ARG124F, ARG18E, ARG18F, ARG55E, ARG55F, ARG70E, ARG70F, ARG83E, ARG83F, ASN13E, ASN19E, ASN34E, ASN34F, ASN53E, ASN53F, ASN99E, ASN99F, ASP110E, ASP110F, ASP42E, ASP42F, ASP67E, ASP67F, CYS75E, CYS75F, GLN49E, GLN49F, GLN86E, GLN86F, GLN96E, GLN96F, GLU82E, GLU82F, GLY88E, GLY88F, GLY89E, GLY89F, GLY93E, GLY93F, HIS112E, HIS112F, HIS117E, HIS117F, HIS51E, HIS51F, HIS63E, HIS63F, HIS76E, HIS76F, ILE111E, ILE111F, ILE38E, ILE38F, ILE41E, ILE41F, ILE46E, ILE46F, ILE74E, ILE74F, ILE98E, ILE98F, LEU104E, LEU104F, LEU109E, LEU109F, LEU14E, LEU14F, LEU15E, LEU15F, LEU43E, LEU43F, LEU45E, LEU45F, LEU77E, LEU77F, LEU87E, LEU87F, LEU92E, LEU92F, LYS101E, LYS101F, LYS105E, LYS105F, LYS26E, LYS26F, LYS48E, LYS48F, MET54E, MET54F, MET80E, MET80F, PHE59E, PHE59F, PRO108E, PRO108F, SER100E, SER100F, SER106E, SER106F, SER44E, SER44F, THR102E, THR102F, THR12E, THR17E, THR17F, THR47E, THR47F, THR71E, THR71F, THR79E, THR79F, THR94E, THR94F, THR95E, THR95F, TRP52E, TRP52F, TYR107E, TYR107F, TYR16E, TYR16F, VAL37E, VAL37F, VAL85E, VAL85F, VAL90E, VAL90F, VAL97E, VAL97F
• E-I: ALA122I, ALA126I, ALA129I, ALA135I, ALA145E, ALA145I, ALA150E, ALA150I, ALA151E, ALA151I, ALA78E, ALA81E, ARG124I, ARG133I, ARG153I, ARG18E, ARG83E, ASN130I, ASN19E, ASP123I, ASP131I, ASP141E, ASP142E, ASP143E, ASP146E, ASP146I, ASP154I, ASP156I, ASP20E, GLN115I, GLN86E, GLU120I, GLU163I, GLU25E, GLU82E, GLY137I, GLY88E, HIS76E, ILE127I, ILE136I, ILE147E, ILE162I, ILE166I, LEU118I, LEU121I, LEU148E, LEU148I, LEU155I, LEU159I, LEU15E, LEU87E, LYS119I, LYS134I, LYS157I, LYS26E, MET80E, PHE158I, PHE161I, SER152I, SER164I, SER22E, THR144E, THR149E, THR149I, THR17E, THR79E, TRP160I, TYR125I, TYR16E, VAL132I, VAL21E, VAL85E
• E-L: ALA57E, ALA57L, ALA61E, ALA61L, ARG55E, ASN113E, ASN165L, ASN53E, ASN58E, ASN58L, GLN115L, GLU163L, GLU167E, GLU167L, GLU64E, GLU64L, GLY56E, HIS51E, HIS63E, HIS63L, ILE162L, ILE166L, ILE60E, ILE60L, LEU118L, LEU159L, LEU66L, LYS157L, MET54E, MET65L, PHE158L, PHE161L, PHE59E, PHE59L, PHE69L, SER164L, TRP160L, TRP52E, VAL114E, VAL114L, VAL62E, VAL62L
• F-I: ALA50F, ALA57F, ALA57I, ALA61F, ALA61I, ARG55F, ASN113F, ASN165I, ASN53F, ASN58F, ASN58I, GLN115I, GLU163I, GLU167F, GLU167I, GLU64F, GLU64I, GLY56F, HIS51F, HIS63F, HIS63I, ILE162I, ILE166I, ILE60F, ILE60I, LEU118I, LEU159I, LEU66I, LYS157I, MET54F, MET65I, PHE158I, PHE161I, PHE59F, PHE59I, PHE69I, SER164I, TRP160I, TRP52F, VAL114F, VAL114I, VAL62F, VAL62I
• F-L: ALA122L, ALA126L, ALA129L, ALA145F, ALA145L, ALA150F, ALA150L, ALA151F, ALA151L, ALA78F, ALA81F, ARG124L, ARG133L, ARG153L, ARG18F, ARG83F, ASN130L, ASN19F, ASP123L, ASP131L, ASP141F, ASP142F, ASP143F, ASP146F, ASP146L, ASP154L, ASP156L, ASP20F, GLN115L, GLN86F, GLU120L, GLU163L, GLU25F, GLU82F, GLY137L, GLY88F, HIS76F, ILE127L, ILE136L, ILE147F, ILE162L, ILE166L, LEU118L, LEU121L, LEU148F, LEU148L, LEU155L, LEU159L, LEU15F, LEU87F, LYS119L, LYS134L, LYS157L, LYS26F, MET80F, PHE158L, PHE161L, SER152L, SER164L, SER22F, THR144F, THR149F, THR149L, THR17F, THR79F, TRP160L, TYR125L, TYR16F, VAL132L, VAL21F, VAL85F
• G-H: ALA50G, ALA50H, ALA78G, ALA78H, ALA81G, ALA81H, ALA84G, ALA84H, ALA91G, ALA91H, ARG124G, ARG124H, ARG18G, ARG18H, ARG55G, ARG55H, ARG70G, ARG70H, ARG83G, ARG83H, ASN13G, ASN13H, ASN34G, ASN34H, ASN53G, ASN53H, ASN99G, ASN99H, ASP110G, ASP110H, ASP42G, ASP42H, ASP67G, ASP67H, CYS75G, CYS75H, GLN49G, GLN49H, GLN86G, GLN86H, GLN96G, GLN96H, GLU82G, GLU82H, GLY88G, GLY88H, GLY89G, GLY89H, GLY93G, GLY93H, HIS112G, HIS112H, HIS117G, HIS117H, HIS51G, HIS51H, HIS63G, HIS63H, HIS76G, HIS76H, ILE111G, ILE111H, ILE38G, ILE38H, ILE41G, ILE41H, ILE46G, ILE46H, ILE74G, ILE74H, ILE98G, ILE98H, LEU104G, LEU104H, LEU109G, LEU109H, LEU14G, LEU14H, LEU15G, LEU15H, LEU43G, LEU43H, LEU45G, LEU45H, LEU77G, LEU77H, LEU87G, LEU87H, LEU92G, LEU92H, LYS101G, LYS101H, LYS105G, LYS105H, LYS26G, LYS26H, LYS48G, LYS48H, MET54G, MET54H, MET80G, MET80H, PHE59G, PHE59H, PRO108G, PRO108H, SER100G, SER100H, SER106G, SER106H, SER44G, SER44H, THR102G, THR102H, THR12H, THR17G, THR17H, THR47G, THR47H, THR71G, THR71H, THR79G, THR79H, THR94G, THR94H, THR95G, THR95H, TRP52G, TRP52H, TYR107G, TYR107H, TYR16G, TYR16H, VAL37G, VAL37H, VAL85G, VAL85H, VAL90G, VAL90H, VAL97G, VAL97H
• G-J: ALA122J, ALA126J, ALA129J, ALA135J, ALA145G, ALA145J, ALA150G, ALA150J, ALA151G, ALA151J, ALA78G, ALA81G, ARG124J, ARG133J, ARG153J, ARG18G, ARG83G, ASN130J, ASN19G, ASP123J, ASP131J, ASP141G, ASP142G, ASP143G, ASP146G, ASP146J, ASP154J, ASP156J, ASP20G, GLN115J, GLN86G, GLU120J, GLU163J, GLU25G, GLU82G, GLY137J, GLY88G, HIS76G, ILE127J, ILE136J, ILE147G, ILE162J, ILE166J, LEU118J, LEU121J, LEU148G, LEU148J, LEU155J, LEU159J, LEU15G, LEU87G, LYS119J, LYS134J, LYS157J, LYS26G, MET80G, PHE158J, PHE161J, SER152J, SER164J, SER22G, THR144G, THR149G, THR149J, THR17G, THR79G, TRP160J, TYR125J, TYR16G, VAL132J, VAL21G, VAL85G
• G-K: ALA50G, ALA57G, ALA57K, ALA61G, ALA61K, ARG55G, ASN113G, ASN165K, ASN53G, ASN58G, ASN58K, GLN115K, GLU163K, GLU167G, GLU167K, GLU64G, GLU64K, GLY56G, HIS51G, HIS63G, HIS63K, ILE162K, ILE166K, ILE60G, ILE60K, LEU118K, LEU159K, LEU66K, LYS157K, MET54G, MET65K, PHE158K, PHE161K, PHE59G, PHE59K, PHE69K, SER164K, TRP160K, TRP52G, VAL114G, VAL114K, VAL62G, VAL62K
• H-J: ALA57H, ALA57J, ALA61H, ALA61J, ARG55H, ASN113H, ASN165J, ASN53H, ASN58H, ASN58J, GLN115J, GLU163J, GLU167H, GLU167J, GLU64H, GLU64J, GLY56H, HIS51H, HIS63H, HIS63J, ILE162J, ILE166J, ILE60H, ILE60J, LEU118J, LEU159J, LEU66J, LYS157J, MET54H, MET65J, PHE158J, PHE161J, PHE59H, PHE59J, PHE69J, SER164J, TRP160J, TRP52H, VAL114H, VAL114J, VAL62H, VAL62J
• H-K: ALA122K, ALA126K, ALA129K, ALA135K, ALA145H, ALA145K, ALA150H, ALA150K, ALA151H, ALA151K, ALA78H, ALA81H, ARG124K, ARG133K, ARG153K, ARG18H, ARG83H, ASN130K, ASN19H, ASP123K, ASP131K, ASP141H, ASP142H, ASP143H, ASP146H, ASP146K, ASP154K, ASP156K, ASP20H, GLN115K, GLN86H, GLU120K, GLU163K, GLU25H, GLU82H, GLY137K, GLY88H, HIS76H, ILE127K, ILE136K, ILE147H, ILE162K, ILE166K, LEU118K, LEU121K, LEU148H, LEU148K, LEU155K, LEU159K, LEU15H, LEU87H, LYS119K, LYS134K, LYS157K, LYS26H, MET80H, PHE158K, PHE161K, SER152K, SER164K, SER22H, THR144H, THR149H, THR149K, THR17H, THR79H, TRP160K, TYR125K, TYR16H, VAL132K, VAL21H, VAL85H
• I-J: ALA50I, ALA50J, ALA78I, ALA78J, ALA81I, ALA81J, ALA84I, ALA84J, ALA91I, ALA91J, ARG124I, ARG124J, ARG18I, ARG18J, ARG55I, ARG55J, ARG70I, ARG70J, ARG83I, ARG83J, ASN13I, ASN13J, ASN19I, ASN19J, ASN34I, ASN34J, ASN53I, ASN53J, ASN99I, ASN99J, ASP110I, ASP110J, ASP42I, ASP42J, ASP67I, ASP67J, CYS75I, CYS75J, GLN49I, GLN49J, GLN86I, GLN86J, GLN96I, GLN96J, GLU82I, GLU82J, GLY88I, GLY88J, GLY89I, GLY89J, GLY93I, GLY93J, HIS112I, HIS112J, HIS117I, HIS117J, HIS51I, HIS51J, HIS63I, HIS63J, HIS76I, HIS76J, ILE111I, ILE111J, ILE38I, ILE38J, ILE41I, ILE41J, ILE46I, ILE46J, ILE74I, ILE74J, ILE98I, ILE98J, LEU104I, LEU104J, LEU109I, LEU109J, LEU14I, LEU14J, LEU15I, LEU15J, LEU43I, LEU43J, LEU45I, LEU45J, LEU77I, LEU77J, LEU87I, LEU87J, LEU92I, LEU92J, LYS101I, LYS101J, LYS105I, LYS105J, LYS26I, LYS26J, LYS48I, LYS48J, MET54I, MET54J, MET80I, MET80J, PHE59I, PHE59J, PRO108I, PRO108J, SER100I, SER100J, SER106I, SER106J, SER44I, SER44J, THR102I, THR102J, THR12I, THR12J, THR17I, THR17J, THR47I, THR47J, THR71I, THR71J, THR79I, THR79J, THR94I, THR94J, THR95I, THR95J, TRP52I, TRP52J, TYR107I, TYR107J, TYR16I, TYR16J, VAL37I, VAL37J, VAL85I, VAL85J, VAL90I, VAL90J, VAL97I, VAL97J
• K-L: ALA50K, ALA50L, ALA78K, ALA78L, ALA81K, ALA81L, ALA84K, ALA84L, ALA91K, ALA91L, ARG124K, ARG124L, ARG18K, ARG18L, ARG55K, ARG55L, ARG70K, ARG70L, ARG83K, ARG83L, ASN13K, ASN19K, ASN19L, ASN34K, ASN34L, ASN53K, ASN53L, ASN99K, ASN99L, ASP110K, ASP110L, ASP42K, ASP42L, ASP67K, ASP67L, CYS75K, CYS75L, GLN49K, GLN49L, GLN86K, GLN86L, GLN96K, GLN96L, GLU82K, GLU82L, GLY88K, GLY88L, GLY89K, GLY89L, GLY93K, GLY93L, HIS112K, HIS112L, HIS117K, HIS117L, HIS51K, HIS51L, HIS63K, HIS63L, HIS76K, HIS76L, ILE111K, ILE111L, ILE38K, ILE38L, ILE41K, ILE41L, ILE46K, ILE46L, ILE74K, ILE74L, ILE98K, ILE98L, LEU104K, LEU104L, LEU109K, LEU109L, LEU14K, LEU14L, LEU15K, LEU15L, LEU43K, LEU43L, LEU45K, LEU45L, LEU77K, LEU77L, LEU87K, LEU87L, LEU92K, LEU92L, LYS101K, LYS101L, LYS105K, LYS105L, LYS26K, LYS26L, LYS48K, LYS48L, MET54K, MET54L, MET80K, MET80L, PHE59K, PHE59L, PRO108K, PRO108L, SER100K, SER100L, SER106K, SER106L, SER44K, SER44L, THR102K, THR102L, THR17K, THR17L, THR47K, THR47L, THR71K, THR71L, THR79K, THR79L, THR94K, THR94L, THR95K, THR95L, TRP52K, TRP52L, TYR107K, TYR107L, TYR16K, TYR16L, VAL37K, VAL37L, VAL85K, VAL85L, VAL90K, VAL90L, VAL97K, VAL97L