1L6S

crystal structure of porphobilinogen synthase complexed with the inhibitor 4,7-dioxosebacic acid

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 278
  • Norm. En. per Res.: -5.2984
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-238.2214	-275.3583	-959.379	-1472.9587	278	63	21	35240	20	142	125

Interface residues

• A-B: ALA141A, ALA141B, ALA165A, ALA165B, ALA166A, ALA166B, ALA173A, ALA173B, ALA18A, ALA18B, ALA196A, ALA196B, ALA228A, ALA228B, ALA248A, ALA248B, ALA250A, ALA250B, ALA276A, ALA276B, ALA281A, ALA281B, ALA282A, ALA282B, ALA284A, ALA284B, ALA286A, ALA286B, ALA303A, ALA303B, ALA305A, ALA305B, ALA48A, ALA48B, ARG11A, ARG11B, ARG17A, ARG17B, ARG204B, ARG215A, ARG215B, ARG225A, ARG225B, ARG226A, ARG226B, ARG230A, ARG230B, ARG256A, ARG256B, ARG259A, ARG259B, ARG302A, ARG302B, ARG6A, ARG6B, ARG8A, ARG8B, ARG9A, ARG9B, ASN139A, ASN139B, ASN221A, ASN221B, ASN224A, ASN224B, ASP138A, ASP138B, ASP140A, ASP140B, ASP168A, ASP168B, ASP214A, ASP214B, ASP235A, ASP235B, ASP253A, ASP253B, ASP288A, ASP288B, ASP2A, ASP2B, CYS129A, CYS129B, GLN170A, GLN170B, GLN172A, GLN172B, GLN176A, GLN176B, GLN219A, GLN219B, GLN238A, GLN238B, GLN5A, GLN5B, GLU144A, GLU144B, GLU205A, GLU205B, GLU21A, GLU21B, GLU227A, GLU227B, GLU22A, GLU22B, GLU231A, GLU231B, GLU257A, GLU257B, GLU260A, GLU260B, GLU274A, GLU274B, GLU289A, GLU289B, GLU290A, GLU290B, GLU295A, GLU295B, GLU47A, GLU47B, GLY130A, GLY130B, GLY136A, GLY136B, GLY169A, GLY169B, GLY201A, GLY201B, GLY213B, GLY249A, GLY249B, GLY273A, GLY273B, GLY285A, GLY285B, GLY298A, GLY298B, GLY304A, GLY304B, HIS128A, HIS128B, HIS135A, HIS135B, ILE229A, ILE229B, ILE254A, ILE254B, ILE278A, ILE278B, ILE287A, ILE287B, ILE300A, ILE300B, ILE4A, ILE4B, LEU10A, LEU10B, LEU132A, LEU132B, LEU143A, LEU143B, LEU16A, LEU16B, LEU234A, LEU234B, LEU252A, LEU252B, LEU258A, LEU258B, LEU25A, LEU25B, LEU283A, LEU283B, LEU294A, LEU294B, LEU297A, LEU297B, LEU3A, LEU3B, LYS12A, LYS12B, LYS194A, LYS194B, LYS216A, LYS216B, LYS279A, LYS279B, LYS291A, LYS291B, LYS301A, LYS301B, MET167A, MET167B, MET19A, MET19B, MET220A, MET220B, MET223A, MET223B, MET277A, MET277B, MET49A, MET49B, PHE195A, PHE195B, PHE199A, PHE199B, PHE203A, PHE203B, PHE20A, PHE20B, PHE280A, PHE280B, PHE312A, PHE312B, PRO14A, PRO14B, PRO202A, PRO202B, PRO222A, PRO222B, PRO247A, PRO247B, PRO50A, PRO50B, PRO7A, PRO7B, SER13A, SER13B, SER192A, SER192B, SER197A, SER197B, SER198A, SER198B, SER217A, SER217B, SER272A, SER272B, SER296A, SER296B, SER299A, SER299B, THR142A, THR142B, THR193A, THR193B, THR1A, THR1B, THR23A, THR23B, THR24A, THR24B, TYR200A, TYR200B, TYR218A, TYR218B, TYR251A, TYR251B, TYR275A, TYR275B, VAL131A, VAL131B, VAL137A, VAL137B, VAL171A, VAL171B, VAL245A, VAL245B, VAL255A, VAL255B, VAL271A, VAL271B, VAL292A, VAL292B, VAL293A, VAL293B