1L1F

structure of human glutamate dehydrogenase-apo form

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 146
  • Norm. En. per Res.: -3.9083
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-72.1945	40.0878	-425.445	-457.5518	186	33	7	17752	0	59	65
A-C	-20.1875	7.1799	-74.1961	-87.2037	52	8	0	3221	0	20	23
A-D	0.0	0.0	-0.7454	-0.7454	5	0	0	68	0	0	0
A-E	-100.5113	-74.0931	-371.9	-546.5044	147	67	3	17602	2	46	48
A-F	-69.9948	43.9369	-434.446	-460.5039	189	40	9	18187	0	58	64
B-C	0.0	0.0	-0.8019	-0.8019	5	0	0	69	0	0	0
B-D	-106.0906	-75.2445	-389.274	-570.609	146	52	3	17612	3	45	47
B-E	-16.3208	7.6359	-80.1644	-88.8493	51	9	0	3296	0	18	23
B-F	-72.0351	43.2599	-416.873	-445.6482	185	36	7	17793	0	55	63
C-D	-82.333	43.3831	-426.123	-465.0729	187	46	9	18342	1	57	65
C-E	-67.7688	42.2675	-418.612	-444.1133	184	42	9	17949	0	55	61
C-F	-78.084	-72.6657	-370.504	-521.2537	147	64	3	17238	3	46	48
D-E	-86.3334	41.7117	-422.171	-466.7927	186	51	7	18414	0	57	65
D-F	-19.2027	7.4744	-74.3159	-86.0442	50	6	0	3164	0	18	23
E-F	0.0	0.0	-0.7964	-0.7964	5	0	0	69	0	0	0

Interface residues

• A-B: ALA120A, ALA157A, ALA188B, ALA198B, ALA200A, ALA438A, ALA447A, ALA447B, ALA458A, ALA500A, ARG150B, ARG178B, ARG39A, ARG400B, ARG407A, ARG407B, ARG423B, ARG443A, ARG463A, ARG466A, ARG90A, ASN143B, ASN197A, ASN197B, ASN392B, ASN394A, ASN394B, ASN410A, ASN410B, ASN498A, ASP123A, ASP142B, ASP185B, ASP195A, ASP195B, ASP408B, ASP442A, ASP451A, CYS119A, CYS201A, GLN209B, GLN418A, GLN418B, GLN441A, GLN467A, GLN88A, GLU146B, GLU177B, GLU228A, GLU388A, GLU406A, GLU406B, GLU40A, GLU419B, GLU42A, GLU439A, GLU449A, GLU449B, GLU462A, GLU499A, GLY160A, GLY163A, GLY165A, GLY192B, GLY210B, GLY211B, GLY399A, GLY399B, GLY430A, GLY446A, GLY446B, GLY456A, GLY501A, HIS193B, HIS199B, HIS213B, HIS225A, HIS395B, HIS412A, HIS412B, HIS454A, HIS61A, HIS89A, ILE166A, ILE183B, ILE196A, ILE196B, ILE207B, ILE212A, ILE432A, ILE434A, ILE434B, ILE444A, ILE444B, ILE452A, LEU300B, LEU390A, LEU393A, LEU393B, LEU401B, LEU413A, LEU413B, LEU414A, LEU414B, LEU421A, LEU421B, LEU457A, LYS147B, LYS158A, LYS205B, LYS391A, LYS391B, LYS404B, LYS424A, LYS424B, LYS450A, LYS492A, LYS495A, MET415A, MET415B, MET461A, PHE126A, PHE224A, PHE387A, PHE403A, PHE403B, PHE440A, PHE494A, PHE504A, PRO125A, PRO164A, PRO206B, PRO433A, PRO433B, PRO436A, PRO92A, SER181B, SER189B, SER208B, SER397B, SER409A, SER409B, SER416B, SER420B, SER445B, SER448A, SER448B, SER455A, SER464A, THR186B, THR383A, THR402A, THR402B, THR431A, THR431B, THR437A, THR460A, THR503A, THR505A, THR91A, TRP182B, TRP389A, TYR187A, TYR194B, TYR386A, TYR398A, TYR398B, TYR405B, TYR411A, TYR411B, TYR459A, TYR497A, VAL121A, VAL122A, VAL124A, VAL168A, VAL382A, VAL384A, VAL396B, VAL417A, VAL417B, VAL435A, VAL453A, VAL493A, VAL496A, VAL502A
• A-C: ALA157A, ALA157C, ALA188A, ALA188C, ARG150A, ARG150C, ARG70A, ARG70C, ASN143A, ASN143C, ASP142A, ASP142C, ASP185A, ASP185C, ASP72A, ASP72C, GLU146A, GLU146C, GLU155A, GLU155C, GLY160A, GLY160C, GLY192A, GLY192C, GLY74A, GLY74C, HIS193A, HIS193C, ILE166A, ILE166C, ILE191A, ILE191C, LYS147A, LYS147C, LYS158A, LYS158C, LYS159A, LYS159C, MET154A, MET154C, SER189A, SER189C, THR186A, THR186C, THR190A, THR190C, TRP76A, TRP76C, TYR187A, TYR187C, TYR194A, TYR194C
• A-D: HIS193D, PHE504A, PHE504D, TYR194A, TYR194D
• A-E: ALA157A, ALA157E, ALA500A, ALA500E, ALA84A, ALA84E, ARG150A, ARG150E, ARG151A, ARG151E, ARG37A, ARG37E, ARG46A, ARG46E, ARG48A, ARG48E, ARG50A, ARG50E, ARG54A, ARG54E, ARG70A, ARG70E, ARG71A, ARG71E, ARG83A, ARG83E, ASN143A, ASN143E, ASN47A, ASN47E, ASN498A, ASN60A, ASN60E, ASP167A, ASP167E, ASP72A, ASP72E, ASP73A, ASP73E, CYS59A, CYS59E, CYS93A, CYS93E, GLN85A, GLN85E, GLN88A, GLN88E, GLU144A, GLU144E, GLU155A, GLU155E, GLU77A, GLU77E, GLU80A, GLU80E, GLY160A, GLY160E, GLY163A, GLY163E, GLY501A, GLY501E, GLY51A, GLY51E, GLY74A, GLY74E, GLY81A, GLY81E, HIS61A, HIS61E, HIS86A, HIS86E, ILE148A, ILE148E, ILE162A, ILE162E, ILE166A, ILE166E, ILE52A, ILE52E, ILE55A, ILE55E, ILE56A, ILE56E, ILE69A, ILE69E, ILE79A, ILE79E, LEU156A, LEU156E, LEU53A, LEU53E, LEU63A, LEU63E, LEU65A, LEU65E, LYS109A, LYS109E, LYS147A, LYS147E, LYS158A, LYS158E, LYS159A, LYS159E, LYS45A, LYS45E, LYS57A, LYS57E, MET154A, MET154E, PHE161A, PHE161E, PHE504A, PHE504E, PHE67A, PHE67E, PRO58A, PRO58E, PRO68A, PRO68E, SER64A, SER64E, SER66A, SER66E, SER75A, SER75E, THR503A, THR503E, THR505A, THR505E, THR91A, THR91E, TRP76A, TRP76E, TYR497A, TYR497E, TYR82A, TYR82E, VAL105A, VAL105E, VAL49A, VAL49E, VAL502A, VAL502E, VAL62A, VAL62E, VAL78A, VAL78E
• A-F: ALA157F, ALA184A, ALA188A, ALA198A, ALA200F, ALA438F, ALA447A, ALA447F, ALA458F, ALA500F, ARG150A, ARG178A, ARG221F, ARG39F, ARG400A, ARG407A, ARG407F, ARG423A, ARG443F, ARG463F, ARG466F, ARG90F, ASN143A, ASN197A, ASN197F, ASN229F, ASN392A, ASN394A, ASN394F, ASN410A, ASN410F, ASN498F, ASP123F, ASP142A, ASP185A, ASP195A, ASP195F, ASP408A, ASP442F, ASP451F, CYS119F, CYS201F, GLN209A, GLN418A, GLN418F, GLN441F, GLN88F, GLU146A, GLU177A, GLU228F, GLU388F, GLU406A, GLU406F, GLU40F, GLU419A, GLU42F, GLU439F, GLU449A, GLU449F, GLU462F, GLU499F, GLY160F, GLY163F, GLY165F, GLY192A, GLY210A, GLY211A, GLY399A, GLY399F, GLY430F, GLY446A, GLY446F, GLY456F, GLY501F, HIS193A, HIS199A, HIS213A, HIS225F, HIS395A, HIS412A, HIS412F, HIS454F, HIS61F, HIS89F, ILE166F, ILE183A, ILE196A, ILE196F, ILE207A, ILE212F, ILE432F, ILE434A, ILE434F, ILE444A, ILE444F, ILE452F, LEU300A, LEU390F, LEU393A, LEU393F, LEU401A, LEU413A, LEU413F, LEU414A, LEU414F, LEU421A, LEU421F, LEU457F, LYS147A, LYS158F, LYS205A, LYS391A, LYS391F, LYS404A, LYS424A, LYS424F, LYS450F, LYS492F, LYS495F, MET415A, MET415F, MET461F, PHE126F, PHE224F, PHE270F, PHE387F, PHE403A, PHE403F, PHE440F, PHE494F, PHE504F, PRO125F, PRO164F, PRO206A, PRO433A, PRO433F, PRO436F, PRO92F, SER181A, SER189A, SER208A, SER397A, SER409A, SER409F, SER416A, SER416F, SER420A, SER445A, SER448A, SER448F, SER455F, SER464F, THR186A, THR383F, THR402A, THR402F, THR431A, THR431F, THR437F, THR460F, THR503F, THR505F, THR91F, TRP182A, TRP389F, TYR187F, TYR194A, TYR386F, TYR398A, TYR398F, TYR405A, TYR411A, TYR411F, TYR459F, TYR497F, VAL121F, VAL122F, VAL124F, VAL168F, VAL382F, VAL384F, VAL396A, VAL417A, VAL417F, VAL435F, VAL453F, VAL493F, VAL496F, VAL502F
• B-C: HIS193C, PHE504B, PHE504C, TYR194B, TYR194C
• B-D: ALA157B, ALA157D, ALA500B, ALA500D, ALA84B, ALA84D, ARG150B, ARG150D, ARG151B, ARG151D, ARG37B, ARG37D, ARG46B, ARG46D, ARG48B, ARG48D, ARG50B, ARG50D, ARG54B, ARG54D, ARG70B, ARG70D, ARG71B, ARG71D, ARG83B, ARG83D, ASN143B, ASN143D, ASN47B, ASN47D, ASN60B, ASN60D, ASP167B, ASP167D, ASP72B, ASP72D, ASP73B, ASP73D, CYS59B, CYS59D, CYS93B, CYS93D, GLN85B, GLN85D, GLN88B, GLN88D, GLU144B, GLU144D, GLU155B, GLU155D, GLU77B, GLU77D, GLU80B, GLU80D, GLY160B, GLY160D, GLY163B, GLY163D, GLY501B, GLY501D, GLY51B, GLY51D, GLY74B, GLY74D, GLY81B, GLY81D, HIS61B, HIS61D, HIS86B, HIS86D, ILE148B, ILE148D, ILE162B, ILE162D, ILE166B, ILE166D, ILE52B, ILE52D, ILE55B, ILE55D, ILE56B, ILE56D, ILE69B, ILE69D, ILE79B, ILE79D, LEU156B, LEU156D, LEU53B, LEU53D, LEU63B, LEU63D, LEU65B, LEU65D, LYS109B, LYS109D, LYS147B, LYS147D, LYS158B, LYS158D, LYS159B, LYS159D, LYS45B, LYS45D, LYS57B, LYS57D, MET154B, MET154D, PHE161B, PHE161D, PHE504B, PHE504D, PHE67B, PHE67D, PRO58B, PRO58D, PRO68B, PRO68D, SER64B, SER64D, SER66B, SER66D, SER75B, SER75D, THR503B, THR503D, THR505B, THR505D, THR91B, THR91D, TRP76B, TRP76D, TYR497B, TYR497D, TYR82B, TYR82D, VAL105B, VAL105D, VAL49B, VAL49D, VAL502B, VAL502D, VAL62B, VAL62D, VAL78B, VAL78D
• B-E: ALA157B, ALA157E, ALA188B, ALA188E, ARG150B, ARG150E, ARG70B, ARG70E, ASN143B, ASN143E, ASP142B, ASP142E, ASP185B, ASP185E, ASP72B, ASP72E, GLU146B, GLU146E, GLU155B, GLU155E, GLY160B, GLY160E, GLY192B, GLY192E, GLY74B, GLY74E, HIS193B, HIS193E, ILE166B, ILE166E, ILE191B, ILE191E, LYS147B, LYS147E, LYS158B, LYS158E, LYS159B, LYS159E, MET154B, MET154E, SER189B, SER189E, THR186B, THR186E, THR190B, THR190E, TRP76B, TYR187B, TYR187E, TYR194B, TYR194E
• B-F: ALA120B, ALA157B, ALA184F, ALA188F, ALA198F, ALA200B, ALA438B, ALA447B, ALA447F, ALA458B, ALA500B, ARG150F, ARG178F, ARG400F, ARG407B, ARG407F, ARG423F, ARG443B, ARG463B, ARG90B, ASN143F, ASN197B, ASN197F, ASN392F, ASN394B, ASN394F, ASN410B, ASN410F, ASN498B, ASP123B, ASP142F, ASP185F, ASP195B, ASP195F, ASP408F, ASP442B, ASP451B, CYS119B, CYS201B, GLN209F, GLN418B, GLN418F, GLN441B, GLN467B, GLN88B, GLU146F, GLU177F, GLU228B, GLU388B, GLU406B, GLU406F, GLU40B, GLU419F, GLU422F, GLU42B, GLU439B, GLU449B, GLU449F, GLU462B, GLU499B, GLY160B, GLY163B, GLY165B, GLY192F, GLY210F, GLY211F, GLY399B, GLY399F, GLY430B, GLY446B, GLY446F, GLY456B, GLY501B, HIS193F, HIS199F, HIS213F, HIS225B, HIS395F, HIS412B, HIS412F, HIS454B, HIS61B, HIS89B, ILE166B, ILE183F, ILE196B, ILE196F, ILE207F, ILE212B, ILE432B, ILE434B, ILE434F, ILE444B, ILE444F, ILE452B, LEU390B, LEU393B, LEU393F, LEU401F, LEU413B, LEU413F, LEU414B, LEU414F, LEU421B, LEU421F, LEU457B, LYS147F, LYS158B, LYS205F, LYS391B, LYS391F, LYS404F, LYS424B, LYS424F, LYS427B, LYS450B, LYS492B, LYS495B, MET415B, MET415F, MET461B, PHE126B, PHE387B, PHE403B, PHE403F, PHE440B, PHE494B, PHE504B, PRO125B, PRO164B, PRO206F, PRO433B, PRO433F, PRO436B, PRO92B, SER181F, SER189F, SER208F, SER397F, SER409B, SER409F, SER416B, SER416F, SER420F, SER445F, SER448B, SER448F, SER455B, SER464B, THR186F, THR383B, THR402B, THR402F, THR431B, THR431F, THR437B, THR460B, THR503B, THR505B, THR91B, TRP182F, TRP389B, TYR187B, TYR194F, TYR386B, TYR398B, TYR398F, TYR405F, TYR411B, TYR411F, TYR459B, TYR497B, VAL121B, VAL122B, VAL124B, VAL168B, VAL384B, VAL396F, VAL417B, VAL417F, VAL435B, VAL453B, VAL493B, VAL496B, VAL502B
• C-D: ALA157C, ALA188D, ALA198D, ALA200C, ALA438C, ALA447C, ALA447D, ALA458C, ALA500C, ARG150D, ARG178D, ARG221C, ARG39C, ARG400D, ARG407C, ARG407D, ARG423D, ARG443C, ARG463C, ARG466C, ARG90C, ASN143D, ASN197C, ASN197D, ASN229C, ASN392D, ASN394C, ASN394D, ASN410C, ASN410D, ASN498C, ASP123C, ASP142D, ASP185D, ASP195C, ASP195D, ASP408D, ASP442C, ASP451C, CYS119C, CYS201C, GLN209D, GLN418C, GLN418D, GLN441C, GLN88C, GLU146D, GLU177D, GLU228C, GLU388C, GLU406C, GLU406D, GLU40C, GLU419D, GLU42C, GLU439C, GLU449C, GLU449D, GLU462C, GLU499C, GLY160C, GLY163C, GLY165C, GLY192D, GLY210D, GLY211D, GLY399C, GLY399D, GLY430C, GLY446C, GLY446D, GLY456C, GLY501C, HIS193D, HIS199D, HIS213D, HIS225C, HIS395D, HIS412C, HIS412D, HIS454C, HIS61C, HIS89C, ILE166C, ILE183D, ILE196C, ILE196D, ILE207D, ILE212C, ILE432C, ILE434C, ILE434D, ILE444C, ILE444D, ILE452C, LEU300D, LEU390C, LEU393C, LEU393D, LEU401D, LEU413C, LEU413D, LEU414C, LEU414D, LEU421C, LEU421D, LEU457C, LYS147D, LYS205D, LYS391C, LYS391D, LYS404D, LYS424C, LYS424D, LYS427C, LYS450C, LYS492C, LYS495C, MET415C, MET415D, MET461C, PHE126C, PHE224C, PHE270C, PHE387C, PHE403C, PHE403D, PHE440C, PHE494C, PHE504C, PRO125C, PRO164C, PRO206D, PRO433C, PRO433D, PRO436C, PRO92C, SER181D, SER189D, SER208D, SER397D, SER409C, SER409D, SER416C, SER416D, SER420D, SER445D, SER448C, SER448D, SER455C, SER464C, THR186D, THR383C, THR402C, THR402D, THR431C, THR431D, THR437C, THR460C, THR503C, THR505C, THR91C, TRP182D, TRP389C, TYR194D, TYR386C, TYR398C, TYR398D, TYR405D, TYR411C, TYR411D, TYR459C, TYR497C, VAL121C, VAL122C, VAL124C, VAL168C, VAL382C, VAL384C, VAL396D, VAL417C, VAL417D, VAL435C, VAL453C, VAL493C, VAL496C, VAL502C
• C-E: ALA120E, ALA157E, ALA188C, ALA198C, ALA200E, ALA438E, ALA447C, ALA447E, ALA458E, ALA500E, ARG150C, ARG178C, ARG400C, ARG407C, ARG407E, ARG423C, ARG443E, ARG463E, ARG90E, ASN143C, ASN197C, ASN197E, ASN392C, ASN394C, ASN394E, ASN410C, ASN410E, ASN498E, ASP123E, ASP142C, ASP185C, ASP195C, ASP195E, ASP408C, ASP442E, ASP451E, CYS119E, CYS201E, GLN209C, GLN418C, GLN418E, GLN441E, GLN467E, GLN88E, GLU146C, GLU177C, GLU228E, GLU388E, GLU406C, GLU406E, GLU40E, GLU419C, GLU422C, GLU422E, GLU42E, GLU439E, GLU449C, GLU449E, GLU462E, GLU499E, GLY160E, GLY163E, GLY165E, GLY192C, GLY210C, GLY211C, GLY399C, GLY399E, GLY430E, GLY446C, GLY446E, GLY456E, GLY501E, HIS193C, HIS199C, HIS213C, HIS225E, HIS395C, HIS395E, HIS412C, HIS412E, HIS454E, HIS61E, HIS89E, ILE166E, ILE183C, ILE196C, ILE196E, ILE207C, ILE212E, ILE432E, ILE434C, ILE434E, ILE444C, ILE444E, ILE452E, LEU390E, LEU393C, LEU393E, LEU401C, LEU413C, LEU413E, LEU414C, LEU414E, LEU421C, LEU421E, LEU457E, LYS147C, LYS205C, LYS391C, LYS391E, LYS404C, LYS424C, LYS424E, LYS427E, LYS450E, LYS492E, LYS495E, MET415C, MET415E, MET461E, PHE126E, PHE387E, PHE403C, PHE403E, PHE440E, PHE494E, PHE504E, PRO125E, PRO164E, PRO206C, PRO433C, PRO433E, PRO436E, PRO92E, SER181C, SER189C, SER208C, SER397C, SER409C, SER409E, SER416C, SER416E, SER420C, SER445C, SER448C, SER448E, SER455E, SER464E, THR186C, THR383E, THR402C, THR402E, THR431C, THR431E, THR437E, THR460E, THR503E, THR505E, THR91E, TRP182C, TRP389E, TYR194C, TYR386E, TYR398C, TYR398E, TYR405C, TYR411C, TYR411E, TYR459E, TYR497E, VAL121E, VAL122E, VAL124E, VAL168E, VAL384E, VAL396C, VAL417C, VAL417E, VAL435E, VAL453E, VAL493E, VAL496E, VAL502E
• C-F: ALA157C, ALA157F, ALA500C, ALA500F, ALA84C, ALA84F, ARG150C, ARG150F, ARG151C, ARG151F, ARG37C, ARG37F, ARG46C, ARG46F, ARG48C, ARG48F, ARG50C, ARG50F, ARG54C, ARG54F, ARG70C, ARG70F, ARG71C, ARG71F, ARG83C, ARG83F, ASN143C, ASN143F, ASN47C, ASN47F, ASN60C, ASN60F, ASP167C, ASP167F, ASP72C, ASP72F, ASP73C, ASP73F, CYS59C, CYS59F, CYS93C, CYS93F, GLN85C, GLN85F, GLN88C, GLN88F, GLU144C, GLU144F, GLU155C, GLU155F, GLU77C, GLU77F, GLU80C, GLU80F, GLY160C, GLY160F, GLY163C, GLY163F, GLY501C, GLY501F, GLY51C, GLY51F, GLY74C, GLY74F, GLY81C, GLY81F, HIS61C, HIS61F, HIS86C, HIS86F, ILE148C, ILE148F, ILE162C, ILE162F, ILE166C, ILE166F, ILE52C, ILE52F, ILE55C, ILE55F, ILE56C, ILE56F, ILE69C, ILE69F, ILE79C, ILE79F, LEU156C, LEU156F, LEU53C, LEU53F, LEU63C, LEU63F, LEU65C, LEU65F, LYS109C, LYS109F, LYS147C, LYS147F, LYS158C, LYS158F, LYS159C, LYS159F, LYS45C, LYS45F, LYS57C, LYS57F, MET154C, MET154F, PHE152F, PHE161C, PHE161F, PHE504C, PHE504F, PHE67C, PHE67F, PRO58C, PRO58F, PRO68C, PRO68F, SER64C, SER64F, SER66C, SER66F, SER75C, SER75F, THR503C, THR503F, THR505C, THR505F, THR91C, THR91F, TRP76C, TRP76F, TYR497C, TYR497F, TYR82C, TYR82F, VAL105C, VAL105F, VAL49C, VAL49F, VAL502C, VAL502F, VAL62C, VAL62F, VAL78C, VAL78F
• D-E: ALA120D, ALA157D, ALA184E, ALA188E, ALA198E, ALA200D, ALA438D, ALA447D, ALA447E, ALA458D, ALA500D, ARG150E, ARG178E, ARG39D, ARG400E, ARG407D, ARG407E, ARG423E, ARG443D, ARG463D, ARG466D, ARG90D, ASN143E, ASN197D, ASN197E, ASN392E, ASN394D, ASN394E, ASN410D, ASN410E, ASN498D, ASP123D, ASP142E, ASP185E, ASP195D, ASP195E, ASP408E, ASP442D, ASP451D, CYS119D, CYS201D, GLN209E, GLN418D, GLN418E, GLN441D, GLN467D, GLN88D, GLU146E, GLU177E, GLU228D, GLU388D, GLU406D, GLU406E, GLU40D, GLU419E, GLU422E, GLU42D, GLU439D, GLU449D, GLU449E, GLU462D, GLU499D, GLY160D, GLY163D, GLY165D, GLY192E, GLY210E, GLY211E, GLY399D, GLY399E, GLY430D, GLY446D, GLY446E, GLY456D, GLY501D, HIS193E, HIS199E, HIS213E, HIS225D, HIS395E, HIS412D, HIS412E, HIS454D, HIS61D, HIS89D, ILE166D, ILE183E, ILE196D, ILE196E, ILE207E, ILE212D, ILE432D, ILE434D, ILE434E, ILE444D, ILE444E, ILE452D, LEU300E, LEU390D, LEU393D, LEU393E, LEU401E, LEU413D, LEU413E, LEU414D, LEU414E, LEU421D, LEU421E, LEU457D, LYS147E, LYS205E, LYS391D, LYS391E, LYS404E, LYS424D, LYS424E, LYS427D, LYS450D, LYS492D, LYS495D, MET415D, MET415E, MET461D, PHE126D, PHE387D, PHE403D, PHE403E, PHE440D, PHE494D, PHE504D, PRO125D, PRO164D, PRO206E, PRO433D, PRO433E, PRO436D, PRO92D, SER181E, SER189E, SER208E, SER397E, SER409D, SER409E, SER416D, SER416E, SER420E, SER445E, SER448D, SER448E, SER455D, SER464D, THR186E, THR383D, THR402D, THR402E, THR431D, THR431E, THR437D, THR460D, THR503D, THR505D, THR91D, TRP182E, TRP389D, TYR194E, TYR386D, TYR398D, TYR398E, TYR405E, TYR411D, TYR411E, TYR459D, TYR497D, VAL121D, VAL122D, VAL124D, VAL168D, VAL384D, VAL396E, VAL417D, VAL417E, VAL435D, VAL453D, VAL493D, VAL496D, VAL502D
• D-F: ALA157D, ALA157F, ALA188D, ALA188F, ARG150D, ARG150F, ARG70D, ARG70F, ASN143D, ASN143F, ASP185D, ASP185F, ASP72D, ASP72F, GLU146D, GLU146F, GLU155D, GLU155F, GLY160D, GLY160F, GLY192D, GLY192F, GLY74D, GLY74F, HIS193D, HIS193F, ILE166D, ILE166F, ILE191D, ILE191F, LYS147D, LYS147F, LYS158D, LYS158F, LYS159D, LYS159F, MET154D, MET154F, SER189D, SER189F, THR186D, THR186F, THR190D, THR190F, TRP76D, TRP76F, TYR187D, TYR187F, TYR194D, TYR194F
• E-F: HIS193E, PHE504E, PHE504F, TYR194E, TYR194F