1CDK

camp-dependent protein kinase catalytic subunit (e.c.2.7.1.37) (protein kinase a) complexed with protein kinase inhibitor peptide fragment 5-24 (pki(5-24) isoelectric variant ca) and mn2+ adenylyl imidodiphosphate (mnamp-pnp) at ph 5.6 and 7c and 4c

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-I
  • Int. Res.: 94
  • Norm. En. per Res.: -5.6306
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-I	-109.3137	-110.5472	-309.415	-529.2758	94	19	4	10754	9	34	21
A-B	-2.1077	-0.1744	-22.1058	-24.388	30	1	0	1123	0	15	13
B-J	-118.1547	-107.9343	-302.829	-528.918	94	14	3	10731	9	34	21

Interface residues

• A-I: ALA17I, ALA233A, ALA240A, ALA4I, ALA8I, ARG11I, ARG133A, ARG134A, ARG137A, ARG14I, ARG15I, ARG165A, ARG256A, ARG56A, ASN16I, ASN171A, ASP166A, ASP184A, ASP20I, ASP241A, ASP328A, ASP5I, CYS199A, GLN242A, GLN245A, GLN84A, GLU127A, GLU170A, GLU203A, GLU230A, GLY10I, GLY136A, GLY13I, GLY186A, GLY200A, GLY234A, GLY50A, GLY52A, GLY55A, HIS19I, HIS260A, HIS87A, ILE135A, ILE18I, ILE209A, ILE210A, ILE244A, ILE246A, ILE7I, LEU132A, LEU167A, LEU173A, LEU198A, LEU205A, LEU227A, LEU49A, LEU82A, LYS168A, LYS78A, LYS81A, LYS83A, MET128A, PHE129A, PHE187A, PHE238A, PHE239A, PHE327A, PHE54A, PHE6I, PRO169A, PRO202A, PRO236A, PRO237A, PRO243A, PRO258A, SER130A, SER53A, SER9I, THR12I, THR183A, THR1I, THR201A, THR2I, THR48A, THR51A, TYR204A, TYR215A, TYR229A, TYR235A, TYR247A, TYR330A, TYR3I, VAL226A, VAL57A
• A-B: ALA232B, ARG137B, ARG270B, ASN113A, ASN340A, ASP264B, ASP267B, CYS343A, GLN77A, GLU140B, GLU341A, GLU346A, GLY344A, HIS260B, HIS294B, ILE339A, LEU265B, LYS266B, LYS295B, LYS342A, LYS345A, PHE138B, PHE261B, PRO141B, SER139B, SER259B, SER262B, SER263B, SER338A, SER348A
• B-J: ALA17J, ALA233B, ALA240B, ALA4J, ALA8J, ARG11J, ARG133B, ARG134B, ARG137B, ARG14J, ARG15J, ARG165B, ARG256B, ARG56B, ASN16J, ASN171B, ASP166B, ASP184B, ASP20J, ASP241B, ASP328B, ASP5J, CYS199B, GLN242B, GLN245B, GLN84B, GLU127B, GLU170B, GLU203B, GLU230B, GLY10J, GLY136B, GLY13J, GLY186B, GLY200B, GLY234B, GLY50B, GLY52B, GLY55B, HIS19J, HIS260B, HIS87B, ILE135B, ILE18J, ILE209B, ILE210B, ILE244B, ILE246B, ILE7J, LEU132B, LEU167B, LEU173B, LEU198B, LEU205B, LEU227B, LEU49B, LEU82B, LYS168B, LYS78B, LYS81B, LYS83B, MET128B, PHE129B, PHE187B, PHE238B, PHE239B, PHE257B, PHE327B, PHE54B, PHE6J, PRO169B, PRO202B, PRO236B, PRO237B, PRO243B, PRO258B, SER130B, SER53B, SER9J, THR12J, THR183B, THR1J, THR201B, THR2J, THR48B, THR51B, TYR204B, TYR229B, TYR235B, TYR247B, TYR330B, TYR3J, VAL226B, VAL57B