1AM4

complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens)

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: B-E
  • Int. Res.: 93
  • Norm. En. per Res.: -2.6214
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-17.8077	-67.7583	-158.812	-244.378	95	49	7	8581	3	24	15
A-E	-7.3952	11.629	-96.8317	-92.5979	59	5	1	4884	0	12	10
D-E	0.0	0.0	-0.0044	-0.0044	2	0	0	2	0	4	4
D-C	0.0	0.0	-0.0338	-0.0338	2	0	0	10	0	3	0
B-E	-11.3925	-67.6759	-164.719	-243.7874	93	51	7	8538	3	24	15
E-C	0.0	-5.4764	-56.9987	-62.4751	53	3	2	3083	0	17	15
C-F	-11.4428	-68.6558	-148.206	-228.3046	93	47	7	8575	3	24	16

Interface residues

• A-D: ALA196A, ALA206A, ALA209A, ALA210A, ALA215A, ALA513D, ALA559D, ALA88A, ARG126A, ARG566D, ARG568D, ARG85A, ARG86A, ARG94A, ASN188A, ASN192A, ASN194A, ASN202A, ASN217A, ASN220A, ASN539D, ASN592D, ASN632D, ASP208A, ASP511D, ASP538D, ASP557D, ASP563D, ASP565D, GLN561D, GLN574D, GLN616D, GLN634D, GLU127A, GLU562D, GLU595D, GLY200A, GLY512D, GLY515D, GLY560D, GLY82A, ILE120A, ILE211A, ILE216A, ILE219A, ILE83A, LEU195A, LEU203A, LEU204A, LEU213A, LEU567D, LEU570D, LYS122A, LYS189A, LYS214A, LYS505D, LYS596D, MET190A, PHE199A, PHE537D, PHE556D, PHE84A, PRO201A, PRO218A, PRO534D, PRO569D, PRO573D, SER182A, SER185A, SER571D, SER586D, SER588D, SER589D, SER87A, THR123A, THR191A, THR193A, THR212A, THR221A, THR223A, THR535D, THR558D, THR90A, TRP205A, TRP597D, TYR532D, TYR564D, TYR572D, VAL119A, VAL197A, VAL198A, VAL514D, VAL533D, VAL536D, VAL93A
• A-E: ALA646E, ALA651E, ALA672E, ALA675E, ALA676E, ARG37A, ARG647E, ARG94A, ASN101A, ASN42A, ASN89A, ASP576E, ASP670E, GLN110A, GLN502E, GLN91A, GLN97A, GLN98A, GLU549E, GLU671E, GLU95A, GLY103A, GLY547E, GLY548E, ILE504E, ILE546E, ILE673E, LEU104A, LEU40A, LEU611E, LEU649E, LEU674E, LEU677E, LYS607E, LYS650E, LYS653E, LYS99A, MET102A, MET545E, PHE610E, PHE669E, PRO105A, PRO36A, PRO38A, PRO39A, PRO41A, PRO550E, PRO609E, THR608E, THR90A, TYR100A, TYR111A, TYR551E, TYR654E, VAL106A, VAL652E, VAL655E, VAL92A, VAL96A
• D-E: ARG647E, GLU595D
• D-C: GLN59C, LYS631D
• B-E: ALA196B, ALA206B, ALA209B, ALA210B, ALA215B, ALA513E, ALA559E, ALA88B, ARG126B, ARG566E, ARG568E, ARG85B, ARG86B, ARG94B, ASN188B, ASN192B, ASN194B, ASN202B, ASN217B, ASN220B, ASN539E, ASN592E, ASN632E, ASP208B, ASP511E, ASP538E, ASP557E, ASP563E, ASP565E, GLN561E, GLN574E, GLN616E, GLN634E, GLU127B, GLU562E, GLU595E, GLY200B, GLY512E, GLY515E, GLY560E, GLY82B, ILE120B, ILE211B, ILE216B, ILE219B, ILE83B, LEU195B, LEU203B, LEU204B, LEU213B, LEU567E, LEU570E, LYS122B, LYS189B, LYS214B, LYS505E, LYS596E, MET190B, PHE199B, PHE537E, PHE556E, PHE84B, PRO201B, PRO218B, PRO534E, PRO569E, PRO573E, SER185B, SER571E, SER586E, SER588E, SER589E, SER87B, THR123B, THR191B, THR193B, THR212B, THR221B, THR223B, THR535E, THR558E, THR90B, TRP205B, TYR532E, TYR564E, TYR572E, VAL119B, VAL197B, VAL198B, VAL514E, VAL533E, VAL536E, VAL93B
• E-C: ALA206C, ALA209C, ALA210C, ALA215C, ALA630E, ARG620E, ARG663E, ASN146C, ASN217C, ASN632E, ASP136C, ASP148C, ASP208C, ASP618E, ASP621E, ASP622E, GLU627E, GLU640E, GLU656E, GLY143C, HIS140C, ILE147C, ILE211C, ILE216C, ILE219C, ILE617E, ILE626E, LEU145C, LEU213C, LEU619E, LEU629E, LEU660E, LYS207C, LYS214C, LYS628E, LYS631E, LYS633E, LYS635E, PHE135C, PHE144C, PRO139C, PRO218C, PRO623E, PRO636E, PRO639E, SER624E, THR212C, THR625E, THR638E, TRP205C, TYR138C, VAL141C, VAL142C
• C-F: ALA196C, ALA206C, ALA209C, ALA210C, ALA215C, ALA513F, ALA559F, ALA88C, ARG126C, ARG566F, ARG568F, ARG85C, ARG86C, ARG94C, ASN188C, ASN192C, ASN194C, ASN202C, ASN217C, ASN220C, ASN539F, ASN592F, ASN632F, ASP208C, ASP511F, ASP538F, ASP557F, ASP563F, ASP565F, GLN561F, GLN574F, GLN616F, GLN634F, GLU127C, GLU562F, GLU595F, GLY200C, GLY512F, GLY515F, GLY560F, GLY82C, ILE120C, ILE211C, ILE216C, ILE219C, ILE83C, LEU195C, LEU203C, LEU204C, LEU213C, LEU567F, LEU570F, LYS122C, LYS189C, LYS214C, LYS505F, LYS596F, MET190C, PHE199C, PHE537F, PHE556F, PHE84C, PRO201C, PRO218C, PRO534F, PRO569F, PRO573F, SER185C, SER571F, SER586F, SER588F, SER589F, SER87C, THR123C, THR191C, THR193C, THR212C, THR221C, THR223C, THR535F, THR558F, THR90C, TRP205C, TYR532F, TYR564F, TYR572F, VAL119C, VAL197C, VAL198C, VAL514F, VAL533F, VAL536F, VAL93C