superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
46458 37 144 Globin-like
46548 3 134 alpha-helical ferredoxin
46557 2 76 GreA transcript cleavage protein, N-terminal domain
46561 3 58 Ribosomal protein L29 (L29p)
46565 6 85 Chaperone J-domain
46575 1 75 DNA polymerase III theta subunit-like
46579 2 118 Prefoldin
46585 2 84 HR1 repeat
46589 4 78 tRNA-binding arm
46596 1 72 Eukaryotic DNA topoisomerase I, dispensable insert domain
46600 1 44 C-terminal UvrC-binding domain of UvrB
46604 2 47 Epsilon subunit of F1F0-ATP synthase C-terminal domain
46609 4 89 Fe,Mn superoxide dismutase (SOD), N-terminal domain
46689 48 65
46689 48 65 Homeodomain-like
46767 2 82 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
46774 4 115 ARID-like
46785 47 89
46785 47 89 "Winged helix" DNA-binding domain
46894 12 89 C-terminal effector domain of the bipartite response regulators
46906 2 70 Ribosomal protein L11, C-terminal domain
46911 1 73 Ribosomal protein S18
46915 2 94 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
46919 1 46 N-terminal Zn binding domain of HIV integrase
46924 1 65 RNA polymerase subunit RPB10
46929 3 49 DNA helicase RuvA subunit, C-terminal domain
46934 28 57 UBA-like
46938 3 78 CRAL/TRIO N-terminal domain
46942 1 114 Elongation factor TFIIS domain 2
46946 5 92 S13-like H2TH domain
46950 2 88 Double-stranded DNA-binding domain
46955 9 85 Putative DNA-binding domain
46966 10 117 Spectrin repeat
46973 1 104 Enzyme IIa from lactose specific PTS, IIa-lac
46977 5 144 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
46984 1 157 Smac/diablo
46988 2 100 Tubulin chaperone cofactor A
46992 1 99 Ribosomal protein S20
46997 4 57 Bacterial immunoglobulin/albumin-binding domains
47005 2 44 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
47014 3 39 Protozoan pheromone proteins
47027 2 88 Acyl-CoA binding protein
47031 4 114 Second domain of FERM
47040 1 81 Kix domain of CBP (creb binding protein)
47045 2 93 RAP domain-like
47050 2 78 VHP, Villin headpiece domain
47055 1 67 TAF(II)230 TBP-binding fragment
47060 4 74 S15/NS1 RNA-binding domain
47072 2 68 Cysteine alpha-hairpin motif
47077 1 137 T4 endonuclease V
47082 2 134 Fertilization protein
47090 4 71 PGBD-like
47095 9 84 HMG-box
47113 21 93 Histone-fold
47144 1 95 HSC20 (HSCB), C-terminal oligomerisation domain
47148 1 137 Diol dehydratase, gamma subunit
47152 1 162 Methane monooxygenase hydrolase, gamma subunit
47157 1 95 Mitochondrial import receptor subunit Tom20
47162 1 144 Apolipoprotein
47170 1 157 Aspartate receptor, ligand-binding domain
47175 7 124 Cytochromes
47188 1 113 Hemerythrin
47195 2 159 TMV-like viral coat proteins
47203 9 169 Acyl-CoA dehydrogenase C-terminal domain-like
47212 1 94 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
47216 1 200 Proteasome activator reg(alpha)
47220 10 134 alpha-catenin/vinculin-like
47226 7 126 Histidine-containing phosphotransfer domain, HPT domain
47233 3 127 Bacterial GAP domain
47240 11 344 Ferritin-like
47266 22 148 4-helical cytokines
47323 9 175 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47336 7 86 ACP-like
47345 1 83 Colicin E immunity proteins
47353 3 77 Retrovirus capsid dimerization domain-like
47364 4 88 Domain of the SRP/SRP receptor G-proteins
47370 5 120 Bromodomain
47380 1 59 ROP protein
47384 3 73 Homodimeric domain of signal transducing histidine kinase
47391 2 44 Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
47396 3 46 Transcription factor IIA (TFIIA), alpha-helical domain
47401 1 37 Ectatomin subunits
47406 2 33 SinR repressor dimerisation domain-like
47413 24 77 lambda repressor-like DNA-binding domains
47446 2 91 Signal peptide-binding domain
47454 2 58 A DNA-binding domain in eukaryotic transcription factors
47459 7 75 HLH, helix-loop-helix DNA-binding domain
47565 5 120 Insect pheromone/odorant-binding proteins
47571 2 149 Cloroperoxidase
47576 10 161 Calponin-homology domain, CH-domain
47587 2 132 Domain of poly(ADP-ribose) polymerase
47592 3 93 SWIB/MDM2 domain
47598 12 62 Ribbon-helix-helix
47616 28 133 Glutathione S-transferase (GST), C-terminal domain
47644 1 90 Methionine synthase domain
47648 4 68 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
47655 2 148 STAT
47661 5 121 t-snare proteins
47668 1 130 N-terminal domain of cbl (N-cbl)
47672 2 152 Transferrin receptor-like dimerisation domain
47676 2 90 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
47681 1 91 C-terminal domain of B transposition protein
47686 1 66 Anaphylotoxins (complement system)
47694 1 79 Cytochrome c oxidase subunit h
47699 8 100 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
47719 1 31 p53 tetramerization domain
47724 1 90 Domain of early E2A DNA-binding protein, ADDBP
47729 5 82 IHF-like DNA-binding proteins
47741 3 89 CO dehydrogenase ISP C-domain like
47752 1 79 Protein HNS-dependent expression A; HdeA
47757 1 81 Chemotaxis receptor methyltransferase CheR, N-terminal domain
47762 1 89 PAH2 domain
47769 17 76 SAM/Pointed domain
47781 11 75 RuvA domain 2-like
47789 3 69 C-terminal domain of RNA polymerase alpha subunit
47794 4 63 Rad51 N-terminal domain-like
47798 1 87 Barrier-to-autointegration factor, BAF
47802 3 84 DNA polymerase beta, N-terminal domain-like
47807 3 119 5' to 3' exonuclease, C-terminal subdomain
47819 10 101 HRDC-like
47823 2 100 lambda integrase-like, N-terminal domain
47831 1 123 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
47836 6 108 Retroviral matrix proteins
47852 1 142 Hepatitis B viral capsid (hbcag)
47857 2 160 Apolipophorin-III
47862 5 77 Saposin
47869 1 70 Bacteriocin AS-48
47874 3 237 Annexin
47895 3 121 Transducin (alpha subunit), insertion domain
47912 1 107 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
47917 2 124 C-terminal domain of alpha and beta subunits of F1 ATP synthase
47923 2 157 Ypt/Rab-GAP domain of gyp1p
47928 1 105 N-terminal domain of the delta subunit of the F1F0-ATP synthase
47933 2 106 ERP29 C domain-like
47938 1 149 Functional domain of the splicing factor Prp18
47943 5 137 Retrovirus capsid protein, N-terminal core domain
47954 9 107 Cyclin-like
47973 2 153 Ribosomal protein S7
47979 2 74 Iron-dependent repressor protein, dimerization domain
47986 13 95 DEATH domain
48008 1 152 Fatty acid responsive transcription factor FadR, C-terminal domain
48013 5 137 NusB-like
48019 10 108 DNA polymerase III clamp loader subunits, C-terminal domain
48024 1 102 N-terminal domain of DnaB helicase
48029 1 101 FliG
48034 2 98 Guanido kinase N-terminal domain
48045 1 138 Scaffolding protein gpD of bacteriophage procapsid
48050 2 115 Hemocyanin, N-terminal domain
48056 2 260 Di-copper centre-containing domain
48065 7 207 DBL homology domain (DH-domain)
48076 1 132 LigA subunit of an aromatic-ring-opening dioxygenase LigAB
48081 2 266 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
48092 1 124 Transcription factor STAT-4 N-domain
48097 6 156 Regulator of G-protein signaling, RGS
48108 1 153 Carbamoyl phosphate synthetase, large subunit connection domain
48113 6 316 Heme-dependent peroxidases
48140 1 143 Ribosomal protein L19 (L19e)
48145 1 158 Influenza virus matrix protein M1
48150 10 207 DNA-glycosylase
48163 2 181 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
48168 2 187 R1 subunit of ribonucleotide reductase, N-terminal domain
48173 4 271 Cryptochrome/photolyase FAD-binding domain
48179 10 173 6-phosphogluconate dehydrogenase C-terminal domain-like
48201 3 71 Uteroglobin-like
48208 12 386 Six-hairpin glycosidases
48225 4 476 Seven-hairpin glycosidases
48230 6 358 Chondroitin AC/alginate lyase
48239 7 352 Terpenoid cyclases/Protein prenyltransferases
48256 3 412 Citrate synthase
48264 16 410 Cytochrome P450
48295 2 99 TrpR-like
48300 2 47 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
48305 1 75 Class II MHC-associated invariant chain ectoplasmic trimerization domain
48310 2 398 Aldehyde ferredoxin oxidoreductase, C-terminal domains
48317 3 457 Acid phosphatase/Vanadium-dependent haloperoxidase
48334 2 286 DNA repair protein MutS, domain III
48340 1 300 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
48345 3 230 A virus capsid protein alpha-helical domain
48350 4 190 GTPase activation domain, GAP
48366 1 469 Ras GEF
48425 3 198 Sec7 domain
48431 1 336 Lipovitellin-phosvitin complex, superhelical domain
48435 1 450 Bacterial muramidases
48439 2 324 Protein prenylyltransferase
48445 1 228 14-3-3 protein
48452 15 155 TPR-like
48464 6 144 ENTH/VHS domain
48479 1 105 Cytochrome c oxidase subunit E
48484 2 613 Lipoxigenase
48493 1 217 gene 59 helicase assembly protein
48498 22 115 Tetracyclin repressor-like, C-terminal domain
48508 17 242 Nuclear receptor ligand-binding domain
48537 3 253 Phospholipase C/P1 nuclease
48552 5 190 Serum albumin-like
48557 8 497 L-aspartase-like
48576 8 311 Terpenoid synthases
48592 2 255 GroEL equatorial domain-like
48600 7 120 Chorismate mutase II
48608 1 156 Peridinin-chlorophyll protein
48613 13 210 Heme oxygenase-like
48619 3 123 Phospholipase A2, PLA2
48647 1 98 Fungal elicitin
48652 1 90 Tetraspanin
48657 1 152 Repressor of bacterial conjugation FinO
48662 1 46 Ribosomal protein L39e
48666 1 73 Methanol dehydrogenase subunit
48670 2 61 Transducin (heterotrimeric G protein), gamma chain
48674 1 88 Fe-only hydrogenase smaller subunit
48678 1 87 Moesin tail domain
48686 1 29 Proteinase A inhibitor IA3
48690 1 47 Epsilon subunit of mitochondrial F1F0-ATP synthase
48695 6 108 Multiheme cytochromes
63446 2 58 Type I dockerin domain
63451 3 53 LEM domain
63491 3 99 BAG domain
63501 1 122 Frizzled cysteine-rich domain
63515 1 162 Outer surface protein C (OspC)
63520 2 110 PTS-regulatory domain, PRD
63562 2 90 RPB6/omega subunit-like
63570 4 96 PABC (PABP) domain
63592 1 98 Flagellar transcriptional activator FlhD
63600 2 192 Telomeric repeat binding factor (TRF) dimerisation domain
68906 6 46 SAP domain
68912 1 44 Rho termination factor, N-terminal domain
68918 1 54 Recombination endonuclease VII, C-terminal and dimerization domains
68989 1 72 Hemolysin expression modulating protein HHA
68993 1 142 FAT domain of focal adhesion kinase
69000 2 108 FAD-dependent thiol oxidase
69008 1 99 RecG, N-terminal domain
69012 2 153 alpha-ketoacid dehydrogenase kinase, N-terminal domain
69025 1 84 Hypothetical protein MTH865
69036 1 64 Bcr-Abl oncoprotein oligomerization domain
69047 1 69 Hypothetical protein YjbJ
69055 2 95 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
69060 1 174 Arp2/3 complex 21 kDa subunit ARPC3
69070 1 89 Anti-sigma factor AsiA
69075 1 97 Glutamyl tRNA-reductase dimerization domain
69099 1 156 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
69103 1 139 Arp2/3 complex 16 kDa subunit ARPC5
69125 2 47 Nuclear receptor coactivator interlocking domain
69131 1 78 Quinohemoprotein amine dehydrogenase C chain
74731 1 60 Ribosomal protein L20
74748 1 269 Variable surface antigen VlsE
74778 1 160 Aconitase B, N-terminal domain
74784 1 217 Translin
81273 2 46 H-NS histone-like proteins
81382 1 55 Skp1 dimerisation domain-like
81383 3 83 F-box domain
81585 3 58 DNA polymerase beta-like, second domain
81593 5 128 Nucleotidyltransferase substrate binding subunit/domain
81601 1 68 Protein serine/threonine phosphatase 2C, C-terminal domain
81631 4 146 PAP/OAS1 substrate-binding domain
81698 2 66 FF domain
81710 1 88 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
81730 1 65 beta-catenin-interacting protein ICAT
81736 2 103 Group V grass pollen allergen
81761 1 145 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
81767 1 122 Pre-protein crosslinking domain of SecA
81778 1 78 Crustacean CHH/MIH/GIH neurohormone
81783 1 83 C-terminal domain of DFF45/ICAD (DFF-C domain)
81790 1 99 Myosin phosphatase inhibitor 17kDa protein, CPI-17
81799 1 99 Putative methyltransferase TM0872, insert domain
81811 2 102 Helical domain of Sec23/24
81822 1 176 RuBisCo LSMT C-terminal, substrate-binding domain
81832 1 165 SopE-like GEF domain
81837 1 304 BEACH domain
81853 2 354 Family 10 polysaccharide lyase
81872 1 196 BRCA2 helical domain
81878 1 30 BRCA2 tower domain
81886 2 208 Helical scaffold and wing domains of SecA
81891 3 226 Poly A polymerase C-terminal region-like
81901 2 199 HCP-like
81923 3 139 Double Clp-N motif
81930 1 174 Orange carotenoid protein, N-terminal domain
81935 1 100 N-terminal domain of bifunctional PutA protein
88659 7 71 Sigma3 and sigma4 domains of RNA polymerase sigma factors
88688 5 99 Families 57/38 glycoside transferase middle domain
89000 3 85 post-HMGL domain-like
89009 3 95 GAT-like domain
89028 3 152 Cobalamin adenosyltransferase-like
89043 1 60 Soluble domain of poliovirus core protein 3a
89064 1 65 Replisome organizer (g39p helicase loader/inhibitor protein)
89069 1 66 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
89082 1 94 Antibiotic binding domain of TipA-like multidrug resistance regulators
89095 3 71 GatB/YqeY motif
89124 1 236 Nop domain
89155 2 197 TorD-like
89162 1 186 Gametocyte protein Pfg27
100909 1 150 IP3 receptor type 1 binding core, domain 2
100910 1 101 Chemosensory protein Csp2
100934 2 104 Heat shock protein 70kD (HSP70), C-terminal subdomain
100957 1 30 Dimerization cofactor of HNF-1 alpha
100985 1 46 Sporulation inhibitor Sda
101059 1 101 B-form DNA mimic Ocr
101082 1 187 Typo IV secretion system protein TraC
101089 2 52 Phosphoprotein XD domain
101094 2 140 Staphylocoagulase
101112 1 112 Oxygen-evolving enhancer protein 3,
101116 2 111 Flagellar export chaperone FliS
101125 1 87 Colicin D immunity protein
101148 2 148 Plant invertase/pectin methylesterase inhibitor
101152 1 185 Mob1/phocein
101156 1 54 Nonstructural protein ns2, Nep, M1-binding domain
101160 1 48 Dimerisation domain of CENP-B
101166 1 60 Docking domain A of the erythromycin polyketide synthase (DEBS)
101173 1 60 Docking domain B of the erythromycin polyketide synthase (DEBS)
101215 2 95 KaiA/RbsU domain
101224 1 87 HAND domain of the nucleosome remodeling ATPase ISWI
101233 1 111 PWI domain
101238 2 58 XPC-binding domain
101257 2 76 Flavivirus capsid protein C
101262 1 189 Methenyltetrahydrofolate cyclohydrolase-like
101278 1 176 N-terminal domain of adenylylcyclase associated protein, CAP
101283 1 54 GRIP domain
101288 6 55 L27 domain
101307 1 158 YutG-like
101312 1 145 Invasion protein A (SipA) , C-terminal actin binding domain
101322 1 213 YcfC-like
101327 1 168 YgfB-like
101332 1 119 Hypothetical protein MTH393
101344 1 213 Superantigen MAM
101353 1 212 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
101386 8 125 all-alpha NTP pyrophosphatases
101391 1 194 Hsp90 co-chaperone CDC37
101399 1 335 P40 nucleoprotein
101420 1 152 C-terminal domain of Ku80
101424 1 159 Hypothetical protein ST1625
101447 2 360 Formin homology 2 domain (FH2 domain)
101473 1 207 Citrobacter dihydroxyacetone kinase extra ATP-binding domain
101478 1 301 ADP-ribosylglycohydrolase
101489 1 100 Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain
101494 1 124 Stathmin
101498 1 77 Anti-sigma factor FlgM
103657 3 208 BAR/IMD domain-like
109604 5 0 HD-domain/PDEase-like
109631 1 89 Transcriptional repressor TraM
109635 1 104 DnaK suppressor protein DksA, alpha-hairpin domain
109640 1 64 KRAB domain (Kruppel-associated box)
109709 2 104 KorB DNA-binding domain-like
109715 1 70 DEK C-terminal domain
109728 1 74 Hypothetical protein AF0491, middle domain
109732 1 83 HBS1-like domain
109736 1 68 FGAM synthase PurL, linker domain
109747 1 66 Glycogen synthesis protein GlgS
109751 1 90 Alpha-hemoglobin stabilizing protein AHSP
109755 4 185 PhoU-like
109770 1 117 Nickel-containing superoxide dismutase, NiSOD
109775 1 194 Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain
109779 1 128 Domain from hypothetical 2610208m17rik protein
109797 2 94 Bacteriocin immunity protein-like
109801 1 62 Hypothetical protein D-63
109805 1 63 Phenylalanine zipper
109839 1 176 Cag-Z
109843 1 192 CAPPD, an extracellular domain of amyloid beta A4 protein
109854 2 154 DinB/YfiT-like putative metalloenzymes
109859 1 50 NblA-like
109880 1 167 A middle domain of Talin 1
109885 3 151 I/LWEQ domain
109905 1 88 Surp module (SWAP domain)
109910 1 82 YgfY-like
109915 1 112 Hypothetical protein YhaI
109920 1 121 Hypothetical protein At3g22680
109925 1 74 Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
109993 1 249 VPS9 domain
109998 2 151 Triger factor/SurA peptide-binding domain-like
110004 1 198 Glycolipid transfer protein, GLTP
110009 1 137 Product of RIKEN cDNA 3110009e22
110014 1 147 Her-1
110019 1 367 ERO1-like
110035 1 99 GDNF receptor-like
116742 3 91 eIF2alpha middle domain-like
116768 1 127 DNA-binding domain of EIN3-like
116820 1 62 Rps17e-like
116842 1 67 XseB-like
116846 2 85 MIT domain
116854 1 105 Avirulence protein AvrPto
116858 1 53 Hypothetical membrane protein Ta0354, soluble domain
116878 1 173 TrmE connector domain
116907 1 164 Hook domain
116915 1 131 Hypothetical protein YqbG
116922 1 81 YugE-like
116927 2 76 EspA/CesA-like
116942 1 224 RNA-binding protein She2p
116960 1 168 YfbU-like
116965 1 286 Hypothetical protein MPN330
117018 1 260 ATP-dependent DNA ligase DNA-binding domain
117023 1 131 DNA primase DnaG, C-terminal domain
140102 1 80 ISY1 domain-like
140106 1 47 Calcyclin-binding protein-like
140111 3 78 Endosomal sorting complex assembly domain
140121 1 73 SPy1572-like
140125 2 56 Rabenosyn-5 Rab-binding domain-like
140129 1 59 MxiH-like
140319 1 64 IscX-like
140356 2 98 PPK N-terminal domain-like
140361 1 83 MIT domain-like
140367 1 73 Coronavirus NSP7-like
140371 1 85 Vng1086c-like
140376 1 75 ChaB-like
140383 2 68 BSD domain-like
140404 1 79 EF2458-like
140415 3 115 YppE-like
140423 1 181 MW0975(SA0943)-like
140427 1 94 VPS28 C-terminal domain-like
140453 2 96 EsxAB dimer-like
140459 2 125 PE/PPE dimer-like
140478 1 126 LemA-like
140482 1 101 MAST3 pre-PK domain-like
140486 1 124 PA2201 N-terminal domain-like
140490 1 105 Nqo1C-terminal domain-like
140496 1 79 HP1531-like
140500 1 54 BAS1536-like
140506 1 70 FHV B2 protein-like
140560 1 76 TM0693-like
140566 1 126 FlgN-like
140570 1 160 MukF C-terminal domain-like
140576 1 81 HIV integrase-binding domain
140581 1 68 TraM-like
140586 1 91 Dcp2 domain-like
140591 2 92 Type III secretion system domain
140607 1 123 EF2947-like
140612 1 59 EB1 dimerisation domain-like
140652 1 74 YozE-like
140657 2 142 Hyaluronidase post-catalytic domain-like
140663 2 118 TTHA0068-like
140670 1 94 YoaC-like
140683 1 79 SP0561-like
140688 1 105 YfmB-like
140693 2 276 IpaD-like
140713 1 63 Phage replication organizer domain
140718 2 104 Mediator hinge subcomplex-like
140726 1 111 AF0941-like
140731 1 155 PA2201 C-terminal domain-like
140736 1 140 Rv1873-like
140741 1 157 RUN domain-like
140746 1 201 SipA N-terminal domain-like
140753 1 147 PG0816-like
140804 1 126 YidB-like
140809 2 411 Rhabdovirus nucleoprotein-like
140856 1 133 USP8 N-terminal domain-like
140860 1 334 Pseudo ankyrin repeat-like
140864 1 346 TROVE domain-like
140869 1 148 GUN4-like
140914 1 207 PriB N-terminal domain-like
140919 1 162 DNA terminal protein
140924 3 283 Duffy binding domain-like
140931 1 172 Fic-like
140959 3 330 Indolic compounds 2,3-dioxygenase-like
140979 1 287 Topoisomerase V catalytic domain-like
140984 3 298 PTPA-like
140990 1 163 FtsH protease domain-like
140996 1 83 Hermes dimerisation domain
141000 1 92 Glu-tRNAGln amidotransferase C subunit
141004 1 61 RelB-like
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
48726 46 107 Immunoglobulin
49265 47 103 Fibronectin type III
49299 3 98 PKD domain
49303 5 105 beta-Galactosidase/glucuronidase domain
49309 8 107 Transglutaminase, two C-terminal domains
49313 7 112 Cadherin-like
49319 2 110 Actinoxanthin-like
49329 4 154 Cu,Zn superoxide dismutase-like
49344 2 187 CBD9-like
49348 5 136 Clathrin adaptor appendage domain
49354 6 123 PapD-like
49363 1 112 Purple acid phosphatase, N-terminal domain
49367 2 106 Superoxide reductase-like
49373 6 95 Invasin/intimin cell-adhesion fragments
49380 1 155 Diphtheria toxin, C-terminal domain
49384 8 142 Carbohydrate-binding domain
49401 10 142 Bacterial adhesins
49410 1 130 Alpha-macroglobulin receptor domain
49417 8 197 p53-like transcription factors
49441 1 187 Cytochrome f, large domain
49447 1 253 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
49452 4 101 Starch-binding domain-like
49464 3 91 Carboxypeptidase regulatory domain-like
49468 1 150 VHL
49472 1 115 Transthyretin (synonym: prealbumin)
49478 3 88 Cna protein B-type domain
49482 4 251 Aromatic compound dioxygenase
49493 4 81 HSP40/DnaJ peptide-binding domain
49498 1 74 alpha-Amylase inhibitor tendamistat
49503 32 138 Cupredoxins
49562 17 134 C2 domain (Calcium/lipid-binding domain, CaLB)
49584 3 85 Periplasmic chaperone C-domain
49590 1 94 PHL pollen allergen
49594 1 109 Rab geranylgeranyltransferase alpha-subunit, insert domain
49599 4 161 TRAF domain-like
49606 1 79 Neurophysin II
49695 12 96 gamma-Crystallin-like
49723 4 117 Lipase/lipooxygenase domain (PLAT/LH2 domain)
49742 4 152 PHM/PNGase F
49749 5 219 Group II dsDNA viruses VP
49758 1 142 Calpain large subunit, middle domain (domain III)
49764 8 126 HSP20-like chaperones
49772 1 131 Ecotin, trypsin inhibitor
49777 3 164 PEBP-like
49785 21 167 Galactose-binding domain-like
49818 7 217
49830 1 228 ENV polyprotein, receptor-binding domain
49835 5 147 Virus attachment protein globular domain
49842 13 140 TNF-like
49854 5 113 Spermadhesin, CUB domain
49863 6 100 Hyaluronate lyase-like, C-terminal domain
49870 1 207 Osmotin, thaumatin-like protein
49879 15 125 SMAD/FHA domain
49889 1 224 Soluble secreted chemokine inhibitor, VCCI
49894 1 299 Baculovirus p35 protein
49899 17 227 Concanavalin A-like lectins/glucanases
49998 5 434 Amine oxidase catalytic domain
50012 2 116 EV matrix protein
50017 1 288 gp9
50022 12 143 ISP domain
50037 5 62 C-terminal domain of transcriptional repressors
50044 32 75 SH3-domain
50084 4 48 Myosin S1 fragment, N-terminal domain
50090 5 128 Electron transport accessory proteins
50104 11 81 Translation proteins SH3-like domain
50118 4 107 Cell growth inhibitor/plasmid maintenance toxic component
50122 2 50 DNA-binding domain of retroviral integrase
50129 19 163 GroES-like
50151 1 55 SacY-like RNA-binding domain
50156 50 101 PDZ domain-like
50176 2 96 N-terminal domains of the minor coat protein g3p
50182 14 75 Sm-like ribonucleoproteins
50193 2 127 Ribosomal protein L14
50199 1 137 Staphylococcal nuclease
50203 10 100 Bacterial enterotoxins
50242 5 143 TIMP-like
50324 2 230 Inorganic pyrophosphatase
50331 11 77 MOP-like
50341 2 136 CheW-like
50346 4 124 PRC-barrel domain
50353 9 141 Cytokine
50370 14 138 Ricin B-like lectins
50382 2 150 Agglutinin
50386 8 188 STI-like
50405 5 119 Actin-crosslinking proteins
50443 2 203 FucI/AraA C-terminal domain-like
50447 17 99 Translation proteins
50465 6 95 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
50475 22 158 FMN-binding split barrel
50486 5 115 FMT C-terminal domain-like
50494 37 231 Trypsin-like serine proteases
50610 1 80 mu transposase, C-terminal domain
50615 2 72 N-terminal domain of alpha and beta subunits of F1 ATP synthase
50621 7 158 Alanine racemase C-terminal domain-like
50630 13 308 Acid proteases
50677 4 177 ValRS/IleRS/LeuRS editing domain
50685 3 154 Barwin-like endoglucanases
50692 14 119
50692 14 119 ADC-like
50715 2 140 Ribosomal protein L25-like
50723 1 125 Core binding factor beta, CBF
50729 46 115 PH domain-like
50784 3 50 Transcription factor IIA (TFIIA), beta-barrel domain
50789 3 205 Herpes virus serine proteinase, assemblin
50800 5 139 PK beta-barrel domain-like
50809 1 113 XRCC4, N-terminal domain
50814 25 153
50814 25 153 Lipocalins
50876 2 120 Avidin/streptavidin
50882 4 106 beta-Barrel protease inhibitors
50886 2 92 D-aminopeptidase, middle and C-terminal domains
50891 5 149 Cyclophilin-like
50904 2 108 Oncogene products
50911 5 142 Mannose 6-phosphate receptor domain
50916 2 128 Rap30/74 interaction domains
50923 5 197 Hemopexin-like domain
50934 1 235 Tachylectin-2
50939 9 390 Sialidases
50952 1 448 Soluble quinoprotein glucose dehydrogenase
50956 1 353 Thermostable phytase (3-phytase)
50960 1 269 TolB, C-terminal domain
50965 1 386 Galactose oxidase, central domain
50969 5 339 YVTN repeat-like/Quinoprotein amine dehydrogenase
50974 1 459 Nitrous oxide reductase, N-terminal domain
50978 12 328 WD40 repeat-like
50985 2 337 RCC1/BLIP-II
50989 1 327 Clathrin heavy-chain terminal domain
50993 2 370 Peptidase/esterase 'gauge' domain
50998 3 583 Quinoprotein alcohol dehydrogenase-like
51004 1 432 C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
51011 22 85 Glycosyl hydrolase domain
51045 8 38 WW domain
51055 3 52 Carbohydrate binding domain
51064 1 59 Head domain of nucleotide exchange factor GrpE
51069 4 248 Carbonic anhydrase
51081 1 350 Bacteriochlorophyll A protein
51087 2 173 Outer surface protein
51092 1 163 Vitelline membrane outer protein-I (VMO-I)
51096 3 209 delta-Endotoxin (insectocide), middle domain
51101 3 147 Mannose-binding lectins
51110 2 116 alpha-D-mannose-specific plant lectins
51120 1 224 beta-Roll
51126 9 351 Pectin lyase-like
51156 1 82 Insect cysteine-rich antifreeze protein
51161 7 203 Trimeric LpxA-like enzymes
51177 1 87 An insect antifreeze protein
51182 16 0 RmlC-like cupins
51206 15 138 cAMP-binding domain-like
51215 1 161 Regulatory protein AraC
51219 2 196 TRAP-like
51225 2 68 Fibre shaft of virus attachment proteins
51230 7 83 Single hybrid motif
51246 6 94 Rudiment single hybrid motif
51261 2 196 Duplicated hybrid motif
51269 3 68 AFP III-like domain
51274 1 95 Head decoration protein D (gpD, major capsid protein D)
51278 1 122 Urease, beta-subunit
51283 9 144 dUTPase-like
51289 1 102 Tlp20, baculovirus telokin-like protein
51294 5 170 Hedgehog/intein (Hint) domain
51306 3 110 LexA/Signal peptidase
51316 5 149 Mss4-like
51322 1 101 Cyanovirin-N
51327 1 104 Head-binding domain of phage P22 tailspike protein
51332 2 172 E2 regulatory, transactivation domain
51338 14 119 Composite domain of metallo-dependent hydrolases
51344 2 64 Epsilon subunit of F1F0-ATP synthase N-terminal domain
54160 17 73 Chromo domain-like
56037 2 164 PheT/TilS domain
63380 14 106 Riboflavin synthase domain-like
63433 1 118 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
63697 1 157 Olfactory marker protein
63707 1 163 Ganglioside M2 (gm2) activator
63712 1 208 Nicotinic receptor ligand binding domain-like
63724 2 158 Cytolysin/lectin
63737 1 208 Leukotriene A4 hydrolase N-terminal domain
63748 10 107 Tudor/PWWP/MBT
63817 3 194 Sortase
63825 2 129 YWTD domain
63829 4 313 Calcium-dependent phosphotriesterase
63840 1 96 Ribonuclease domain of colicin E3
63848 1 107 Cell-division inhibitor MinC, C-terminal domain
63862 2 90 Thiamin pyrophosphokinase, substrate-binding domain
63867 4 78 MoeA C-terminal domain-like
63877 1 188 Methuselah ectodomain
63882 3 176 MoeA N-terminal region -like
63887 2 90 P-domain of calnexin/calreticulin
69179 4 156 Integrin domains
69189 3 85 Penicillin-binding protein associated domain
69203 2 106 Nucleoplasmin-like core domain
69255 1 124 Tail-associated lysozyme gp5, N-terminal domain
69287 2 72 Urease metallochaperone UreE, N-terminal domain
69298 2 114 Quinohemoprotein amine dehydrogenase A chain, domain 3
69304 1 281 Tricorn protease N-terminal domain
69318 1 452 Integrin alpha N-terminal domain
69322 1 360 Tricorn protease domain 2
69336 1 268 Alpha subunit of glutamate synthase, C-terminal domain
69340 2 157 C-terminal domain of adenylylcyclase associated protein
69349 3 150 Phage fibre proteins
69360 2 190 Cell wall binding repeat
69369 2 261 Cloacin translocation domain
74853 1 113 Lamin A/C globular tail domain
74863 1 121 Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha)
74877 2 126 Major surface antigen p30, SAG1
74914 1 370 V-region of surface antigen I/II (SA I/II, PAC)
74924 8 108 Cap-Gly domain
74942 1 74 YhbC-like, C-terminal domain
74982 1 112 Small protein B (SmpB)
75001 1 118 Dipeptidyl peptidase I (cathepsin C), exclusion domain
75011 1 355 3-carboxy-cis,cis-mucoante lactonizing enzyme
81277 1 101 C-terminal domain of mollusc hemocyanin
81296 40 113 E set domains
81624 6 128 N-terminal domain of MutM-like DNA repair proteins
81653 1 115 Calcium ATPase, transduction domain A
81982 1 131 Antigen MPT63/MPB63 (immunoprotective extracellular protein)
81986 2 63 Tp47 lipoprotein, middle and C-terminal domains
81995 2 168 beta-sandwich domain of Sec23/24
82004 1 81 N-utilization substance G protein NusG, insert domain
82026 1 113 Calcium-mediated lectin
82046 1 371 Viral chemokine binding protein m3
82051 1 156 Obg GTP-binding protein N-terminal domain
82057 4 77 Prokaryotic SH3-related domain
82061 1 203 BAH domain
82093 1 101 Heme chaperone CcmE
82109 2 160 MIR domain
82114 2 132 Riboflavin kinase-like
82153 3 153 FAS1 domain
82171 2 468 DPP6 N-terminal domain-like
82185 1 78 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82199 4 204 SET domain
82215 1 158 C-terminal autoproteolytic domain of nucleoporin nup98
82220 1 191 Tp47 lipoprotein, N-terminal domain
88633 25 239 Positive stranded ssRNA viruses
88645 7 399 ssDNA viruses
88648 2 370 Group I dsDNA viruses
88650 3 157 Satellite viruses
88697 12 131 PUA domain-like
89232 1 110 Hypothetical protein TM1070
89260 1 98 Collagen-binding domain
89360 2 98 HesB-like domain
89372 1 312 Fucose-specific lectin
89392 3 179 Prokaryotic lipoproteins and lipoprotein localization factors
89428 1 533 Adsorption protein p2
89433 1 316 Baseplate structural protein gp8
89442 1 105 Hypothetical protein YojF
89447 3 79 AbrB/MazE/MraZ-like
100920 1 115 Heat shock protein 70kD (HSP70), peptide-binding domain
100939 3 251 SPOC domain-like
101542 1 114 Fungal immunomodulatory protein, FIP
101546 1 155 ASF1-like
101576 1 116 Supernatant protein factor (SPF), C-terminal domain
101596 1 199 Dextranase, N-terminal domain
101601 1 110 Unnamed hypothetical protein
101606 1 117 Superantigen (mitogen) Ypm
101690 2 122 PAZ domain
101697 1 118 Hypothetical protein YfhH
101738 1 106 Stringent starvation protein B, SspB
101744 3 90 Rof/RNase P subunit-like
101751 1 70 Hydrophobin II, HfbII
101756 1 93 Hypothetical protein YgiW
101790 5 85 Aminomethyltransferase beta-barrel domain
101801 2 78 Surface presentation of antigens (SPOA)
101816 1 111 Replicase NSP9
101821 6 84 Aminopeptidase/glucanase lid domain
101852 1 106 Bacterial fluorinating enzyme, C-terminal domain
101874 2 172 YceI-like
101887 1 317 Apyrase
101898 2 268 NHL repeat
101904 2 304 GyrA/ParC C-terminal domain-like
101908 1 333 Putative isomerase YbhE
101931 1 33 Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain
101936 3 130 DNA-binding pseudobarrel domain
101941 1 147 NAC domain
101960 1 410 Stabilizer of iron transporter SufD
101967 1 179 Adhesin YadA, collagen-binding domain
101999 1 158 Trimeric adhesin
102031 1 128 AXH domain
110069 2 120 ApaG-like
110083 1 165 Peptidylarginine deiminase Pad4, middle domain
110087 1 149 DR1885-like metal-binding protein
110111 1 131 Ctag/Cox11
110132 1 153 BTV NS2-like ssRNA-binding domain
110217 1 161 DNA-binding protein LAG-1 (CSL)
110221 1 162 AbfB domain
110296 2 385 Oligoxyloglucan reducing end-specific cellobiohydrolase
110304 2 148 Coronavirus RNA-binding domain
110324 1 66 Ribosomal L27 protein
117066 1 68 Accessory protein X4 (ORF8, ORF7a)
117070 1 151 LEA14-like
117074 1 170 Hypothetical protein PA1324
117100 1 97 Beta-galactosidase LacA, domain 3
117125 1 108 Putative glucosidase YicI, C-terminal domain
117130 1 55 CsrA-like
117143 1 293 Flagellar hook protein flgE
117281 1 285 Kelch motif
117289 2 369 Nucleoporin domain
141066 2 110 ICP-like
141072 2 139 CalX-like
141086 1 99 Agglutinin HPA-like
141091 1 103 L21p-like
141099 1 98 Atu1913-like
141130 1 268 Acetamidase/Formamidase-like
141251 1 107 Kinase-associated protein B-like
141255 1 77 YccV-like
141259 1 80 CarD-like
141300 1 73 GatD N-terminal domain-like
141318 1 159 TM0957-like
141322 1 72 NfeD domain-like
141371 3 117 PilZ domain-like
141447 1 74 PA2021-like
141452 1 154 Hcp1-like
141457 1 146 BH3618-like
141480 3 125 Extracellular hemoglobin linker subunit, receptor domain
141488 1 82 YdhA-like
141493 1 173 Allene oxide cyclase-like
141523 2 120 L,D-transpeptidase catalytic domain-like
141530 1 119 PTSIIA/GutA-like
141562 1 169 At5g01610-like
141571 3 162 Pentapeptide repeat-like
141658 2 148 Bacteriophage trimeric proteins domain
141666 1 78 'SARS ORF9b-like
141673 1 128 MOSC N-terminal domain-like
141678 1 153 MAL13P1.257-like
141694 1 83 PG0164-like
141729 1 116 FimD N-terminal domain-like
141734 1 124 HisI-like
141739 3 174 MFPT repeat-like
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
51351 3 243 Triosephosphate isomerase (TIM)
51366 22 237 Ribulose-phoshate binding barrel
51391 2 214 Thiamin phosphate synthase
51395 17 336 FMN-linked oxidoreductases
51412 3 355 Inosine monophosphate dehydrogenase (IMPDH)
51419 8 240 PLP-binding barrel
51430 8 311 NAD(P)-linked oxidoreductase
51445 33 368 (Trans)glycosidases
51556 25 303 Metallo-dependent hydrolases
51569 37 284 Aldolase
51604 14 249 Enolase C-terminal domain-like
51621 8 315 Phosphoenolpyruvate/pyruvate domain
51645 1 688 Malate synthase G
51649 4 302 RuBisCo, C-terminal domain
51658 10 318 Xylose isomerase-like
51679 6 343 Bacterial luciferase-like
51690 7 245 Nicotinate/Quinolinate PRTase C-terminal domain-like
51695 7 266 PLC-like phosphodiesterases
51703 2 508 Cobalamin (vitamin B12)-dependent enzymes
51713 2 358 tRNA-guanine transglycosylase
51717 4 260 Dihydropteroate synthetase-like
51726 4 357 UROD/MetE-like
51730 2 284 FAD-linked oxidoreductase
51735 26 251 NAD(P)-binding Rossmann-fold domains
51905 27 175 FAD/NAD(P)-binding domain
51971 9 243 Nucleotide-binding domain
51984 3 91 MurCD N-terminal domain
51989 3 336 Glycosyl hydrolases family 6, cellulases
52009 2 128 Phosphohistidine domain
52016 5 198 LeuD/IlvD-like
52021 1 151 Carbamoyl phosphate synthetase, small subunit N-terminal domain
52025 2 211 PA domain
52029 3 167 GroEL apical domain-like
52038 2 88 Barstar-related
52042 1 142 Ribosomal protein L32e
52047 5 284 RNI-like
52058 19 215 L domain-like
52075 1 198 Outer arm dynein light chain 1
52087 3 194 CRAL/TRIO domain
52091 3 112 Anti-sigma factor antagonist SpoIIaa
52096 23 257 ClpP/crotonase
52113 8 106 BRCT domain
52121 3 157 Lumazine synthase
52129 7 262 Caspase-like
52141 4 206 Uracil-DNA glycosylase-like
52151 2 239 FabD/lysophospholipase-like
52156 1 131 Initiation factor IF2/eIF5b, domain 3
52161 1 129 Ribosomal protein L13
52166 2 209 Ribosomal protein L4
52172 29 132 CheY-like
52200 1 145 Toll/Interleukin receptor TIR domain
52206 1 111 Hypothetical protein MTH538
52210 4 147 Succinyl-CoA synthetase domains
52218 20 170 Flavoproteins
52242 5 157 Cobalamin (vitamin B12)-binding domain
52255 1 159 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
52266 8 233 SGNH hydrolase
52279 1 214 Beta-D-glucan exohydrolase, C-terminal domain
52283 10 148 Formate/glycerate dehydrogenase catalytic domain-like
52304 2 148 Type II 3-dehydroquinate dehydratase
52309 6 181 N-(deoxy)ribosyltransferase-like
52313 2 214 Ribosomal protein S2
52317 15 210 Class I glutamine amidotransferase-like
52335 5 154 Methylglyoxal synthase-like
52343 12 145 Ferredoxin reductase-like, C-terminal NADP-linked domain
52374 17 354 Nucleotidylyl transferase
52402 19 225 Adenine nucleotide alpha hydrolases-like
52413 2 122 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
52418 3 265 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
52425 5 192 Cryptochrome/photolyase, N-terminal domain
52440 15 112 PreATP-grasp domain
52467 12 172 DHS-like NAD/FAD-binding domain
52490 2 218 Tubulin nucleotide-binding domain-like
52499 6 204 Isochorismatase-like hydrolases
52507 4 172 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
52518 28 225 Thiamin diphosphate-binding fold (THDP-binding)
52540 45 171 P-loop containing nucleoside triphosphate hydrolases
52728 1 163 PTS IIb component
52733 2 340 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
52738 1 198 Methylesterase CheB, C-terminal domain
52743 7 372 Subtilisin-like
52768 7 324 Arginase/deacetylase
52777 4 238 CoA-dependent acyltransferases
52788 4 140 Phosphotyrosine protein phosphatases I
52794 2 100 PTS system, Lactose/Cellobiose specific IIB subunit
52799 19 234 (Phosphotyrosine protein) phosphatases II
52821 21 136 Rhodanese/Cell cycle control phosphatase
52833 48 105 Thioredoxin-like
52913 1 95 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
52922 6 150 TK C-terminal domain-like
52935 5 141 PK C-terminal domain-like
52943 2 201 ATP synthase (F1-ATPase), gamma subunit
52949 7 171 Macro domain-like
52954 12 120 Class II aaRS ABD-related
52964 1 134 TolB, N-terminal domain
52968 3 133 B12-dependent dehydatase associated subunit
52972 7 189 ITPase-like
52980 7 126 Restriction endonuclease-like
53032 3 89 tRNA-intron endonuclease catalytic domain-like
53036 1 139 Eukaryotic RPB5 N-terminal domain
53041 1 115 Resolvase-like
53056 3 221 beta-carbonic anhydrase, cab
53062 1 129 IIA domain of mannose transporter, IIA-Man
53067 23 120 Actin-like ATPase domain
53092 3 149 Creatinase/prolidase N-terminal domain
53098 2 186 Ribonuclease H-like
53137 4 132 Translational machinery components
53146 3 115 Nitrogenase accessory factor-like
53150 2 148 DNA repair protein MutS, domain II
53155 2 81 Methylated DNA-protein cysteine methyltransferase domain
53163 2 241 HybD-like
53167 11 263 Purine and uridine phosphorylases
53178 2 190 Peptidyl-tRNA hydrolase-like
53182 1 206 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
53187 29 288 Zn-dependent exopeptidases
53213 1 298 LigB subunit of an aromatic-ring-opening dioxygenase LigAB
53218 8 156 Molybdenum cofactor biosynthesis proteins
53223 14 147 Aminoacid dehydrogenase-like, N-terminal domain
53244 7 137 MurD-like peptide ligases, peptide-binding domain
53254 9 317 Phosphoglycerate mutase-like
53271 26 184 PRTase-like
53300 13 205 vWA-like
53323 1 253 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
53328 6 195 Formyltransferase
53383 38 399 PLP-dependent transferases
53448 22 261 Nucleotide-diphospho-sugar transferases
53474 43 272 alpha/beta-Hydrolases
53590 3 313 Nucleoside hydrolase
53597 14 185 Dihydrofolate reductase-like
53613 19 297 Ribokinase-like
53623 7 231 MurD-like peptide ligases, catalytic domain
53633 9 270 Carbamate kinase-like
53639 4 232 AraD-like aldolase/epimerase
53649 8 439 Alkaline phosphatase-like
53659 9 350 Isocitrate/Isopropylmalate dehydrogenase-like
53671 8 180 Aspartate/ornithine carbamoyltransferase
53681 4 120 Aspartate/glutamate racemase
53686 14 362 Tryptophan synthase beta subunit-like PLP-dependent enzymes
53697 6 376 SIS domain
53720 9 472 ALDH-like
53732 3 549 Aconitase iron-sulfur domain
53738 6 130 Phosphoglucomutase, first 3 domains
53743 2 342 FucI/AraA N-terminal and middle domains
53748 2 402 Phosphoglycerate kinase
53756 6 470 UDP-Glycosyltransferase/glycogen phosphorylase
53774 2 338 Glutaminase/Asparaginase
53784 2 435 Phosphofructokinase
53790 7 236 Tetrapyrrole methylase
53795 4 248 PEP carboxykinase-like
53800 4 262 Chelatase
53807 8 275 "Helical backbone" metal receptor
53822 10 290 Periplasmic binding protein-like I
53850 30 286 Periplasmic binding protein-like II
53901 22 205 Thiolase-like
53920 1 312 Fe-only hydrogenase
53927 12 149 Cytidine deaminase-like
56784 44 226 HAD-like
63418 2 98 MurE/MurF N-terminal domain
63892 1 242 Pyridoxine 5'-phosphate synthase
63965 2 196 Precorrin-8X methylmutase CbiC/CobH
63992 1 274 Dipeptide transport protein
63999 2 195 Thiamin pyrophosphokinase, catalytic domain
64005 2 216 Undecaprenyl diphosphate synthase
64043 1 89 Cell-division inhibitor MinC, N-terminal domain
64076 3 118 MTH938-like
64153 2 224 YjeF N-terminal domain-like
64158 1 234 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
64167 2 258 SurE-like
64182 2 286 DHH phosphoesterases
68923 4 219 PEP carboxykinase N-terminal domain
69500 2 166 DTD-like
69572 3 389 Activating enzymes of the ubiquitin-like proteins
69593 1 350 Glycerol-3-phosphate (1)-acyltransferase
69618 2 257 HemD-like
75098 1 457 Monomethylamine methyltransferase MtmB
75138 2 130 HPr kinase/phoshatase HprK N-terminal domain
75169 8 111 DsrEFH-like
75181 1 148 Hypothetical protein MTH777 (MT0777)
75217 13 174 alpha/beta knot
75304 4 469 Amidase signature (AS) enzymes
82282 2 324 Homocysteine S-methyltransferase
82317 1 162 Swiveling domain of dehydratase reactivase alpha subunit
82544 1 411 GckA/TtuD-like
82549 4 304 DAK1/DegV-like
88713 13 277 Glycoside hydrolase/deacetylase
89550 3 219 PHP domain-like
89562 1 156 RraA-like
89623 2 149 Ribose/Galactose isomerase RpiB/AlsB
89733 3 328 L-sulfolactate dehydrogenase-like
89796 3 380 CoA-transferase family III (CaiB/BaiF)
100950 20 236 NagB/RpiA/CoA transferase-like
102110 1 251 (2r)-phospho-3-sulfolactate synthase ComA
102114 3 358 Radical SAM enzymes
102198 2 196 Putative cyclase
102215 1 257 Creatininase
102220 1 110 DNA polymerase III psi subunit
102324 1 266 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
102400 1 147 DNA polymerase III chi subunit
102405 5 176 MoCo carrier protein-like
102414 1 255 Alpha-2,3/8-sialyltransferase CstII
102462 2 116 Peptidyl-tRNA hydrolase II
102522 1 185 Bacterial fluorinating enzyme, N-terminal domain
102546 1 131 Ribose transport protein RbsD
102588 2 254 LmbE-like
102645 2 242 CoaB-like
102705 3 287 NIF3 (NGG1p interacting factor 3)-like
102712 1 108 JAB1/MPN domain
110391 1 168 GlpP-like
110395 1 225 CutC-like
110399 1 237 ThiG-like
110455 2 110 Toprim domain
110581 1 282 Indigoidine synthase A-like
110710 1 189 Hypothetical protein TT1679
110738 1 371 Glycerate kinase I
117396 2 251 TM1631-like
117457 1 170 FumA C-terminal domain-like
141868 1 254 EAL domain-like
141986 1 138 LD-carboxypeptidase A C-terminal domain-like
142019 1 243 Nqo1 FMN-binding domain-like
142338 2 304 CofD-like
142433 1 167 CinA-like
142535 2 272 AF0625-like
142695 1 171 RibA-like
142754 1 271 NadA-like
142764 1 412 YgbK-like
142795 1 297 CAC2185-like
142823 1 228 ComB-like
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
48403 14 213 Ankyrin repeat
53933 4 117 Microbial ribonucleases
53955 12 179 Lysozyme-like
54060 7 170 His-Me finger endonucleases
54076 4 122 RNase A-like
54098 2 104 Prion-like
54106 2 48 LysM domain
54111 1 100 Urease, gamma-subunit
54117 14 71 Interleukin 8-like chemokines
54171 5 70 DNA-binding domain
54184 2 60 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
54189 5 114 Ribosomal proteins S24e, L23 and L15e
54197 8 152 HIT-like
54211 16 174 Ribosomal protein S5 domain 2-like
54236 25 83 Ubiquitin-like
54277 12 90 CAD & PB1 domains
54285 8 80 MoaD/ThiS
54292 18 101 2Fe-2S ferredoxin-like
54328 4 115 Staphylokinase/streptokinase
54334 9 109 Superantigen toxins, C-terminal domain
54358 2 64 Immunoglobulin-binding domains
54364 1 76 Translation initiation factor IF3, N-terminal domain
54368 1 100 Glutamine synthetase, N-terminal domain
54373 15 110 FAD-linked reductases, C-terminal domain
54403 8 110 Paramphistomum epiclitum [TaxId: 54403]
54416 9 109 Amine oxidase N-terminal region
54423 3 60 DsbC/DsbG N-terminal domain-like
54427 21 145 NTF2-like
54441 1 83 Uracil-DNA glycosylase inhibitor protein
54447 6 127 ssDNA-binding transcriptional regulator domain
54452 15 149 MHC antigen-recognition domain
54495 16 144 UBC-like
54506 10 168 Diaminopimelate epimerase-like
54511 3 225 GFP-like
54518 2 212 Tubby C-terminal domain-like
54523 7 131 Pili subunits
54529 2 182 Mitochondrial glycoprotein MAM33-like
54534 10 137 FKBP-like
54552 1 84 Colicin E3 immunity protein
54556 7 74 Chitinase insertion domain
54565 1 83 Ribosomal protein S16
54570 1 80 Ribosomal protein S19
54575 1 82 Ribosomal protein L31e
54580 1 67 Allophycocyanin linker chain (domain)
54585 5 94 Cdc48 domain 2-like
54593 13 157 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
54611 1 134 Bacterial protein-export protein SecB
54616 1 99 DNA-binding domain of Mlu1-box binding protein MBP1
54621 1 173 Heme-binding protein A (HasA)
54626 1 212 Chalcone isomerase
54631 20 66 CBS-domain
54637 45 135 Thioesterase/thiol ester dehydrase-isomerase
54648 1 85 DLC
54654 3 65 CI-2 family of serine protease inhibitors
54665 6 138 CO dehydrogenase molybdoprotein N-domain-like
54675 8 130 Nicotinate/Quinolinate PRTase N-terminal domain-like
54680 3 102 Pyrimidine nucleoside phosphorylase C-terminal domain
54686 2 144 Ribosomal protein L16p/L10e
54690 1 142 Molybdopterin synthase subunit MoaE
54695 8 100 POZ domain
54713 5 118 Elongation factor Ts (EF-Ts), dimerisation domain
54719 4 110 Fe,Mn superoxide dismutase (SOD), C-terminal domain
54736 2 78 ClpS-like
54747 2 78 Ribosomal L11/L12e N-terminal domain
54752 2 60 RecA protein, C-terminal domain
54762 2 82 Signal recognition particle alu RNA binding heterodimer, SRP9/14
54768 16 90 dsRNA-binding domain-like
54782 1 88 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
54786 2 73 YcfA/nrd intein domain
54791 19 85 Eukaryotic type KH-domain (KH-domain type I)
54806 2 75 Alpha-lytic protease prodomain
54810 1 121 GMP synthetase C-terminal dimerisation domain
54814 7 86 Prokaryotic type KH domain (KH-domain type II)
54821 1 101 Ribosomal protein S3 C-terminal domain
54826 16 124 Enolase N-terminal domain-like
54843 2 130 Ribosomal protein L22
54849 2 102 GroEL-intermediate domain like
54857 1 81 DNA damage-inducible protein DinI
54893 2 96 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
54897 6 84 Protease propeptides/inhibitors
54909 27 139 Dimeric alpha+beta barrel
54913 9 95 GlnB-like
54919 1 153 Nucleoside diphosphate kinase, NDK
54928 46 91 RNA-binding domain, RBD
54957 3 106 Viral DNA-binding domain
54966 4 130 RuBisCO, large subunit, small (N-terminal) domain
54975 7 109
54975 7 109 Acylphosphatase/BLUF domain-like
54980 8 77 EF-G C-terminal domain-like
54984 2 90 eEF-1beta-like
54991 1 104 Anticodon-binding domain of PheRS
54995 2 102 Ribosomal protein S6
54999 1 98 Ribosomal protein S10
55008 12 72 HMA, heavy metal-associated domain
55021 23 79 ACT-like
55031 7 109 Bacterial exopeptidase dimerisation domain
55035 2 114 NAD-binding domain of HMG-CoA reductase
55040 1 143 Molybdenum cofactor biosynthesis protein C, MoaC
55044 1 158 TRADD, N-terminal domain
55048 2 66 Probable ACP-binding domain of malonyl-CoA ACP transacylase
55052 2 77 CheY-binding domain of CheA
55056 1 79 Killer toxin KP6 alpha-subunit
55060 8 162 GHMP Kinase, C-terminal domain
55064 1 122 Translational regulator protein regA
55068 2 178 Peptide methionine sulfoxide reductase
55073 5 195 Nucleotide cyclase
55083 1 158 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
55103 4 269 FAD-linked oxidases, C-terminal domain
55112 2 148 Formylmethanofuran:tetrahydromethanopterin formyltransferase
55116 2 160 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55120 7 220 Pseudouridine synthase
55124 2 70 Sulfite reductase, domains 1 and 3
55129 2 107 Ribosomal protein L30p/L7e
55136 4 168 Probable bacterial effector-binding domain
55144 3 196 LigT-like
55149 1 127 Pepsin inhibitor-3
55154 4 191 CYTH-like phosphatases
55159 2 104 eIF1-like
55166 4 182 Hedgehog/DD-peptidase
55174 6 80 Alpha-L RNA-binding motif
55186 2 156 ThrRS/AlaRS common domain
55190 2 115 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
55194 2 134 Ribosome recycling factor, RRF
55200 1 88 Translation initiation factor IF3, C-terminal domain
55205 3 424 EPT/RTPC-like
55221 2 122 Yeast killer toxins
55229 1 58 Cell division protein MinE topological specificity domain
55234 1 68 Cyanase C-terminal domain
55239 4 119 RuBisCO, small subunit
55248 2 88 PCD-like
55252 2 71 C-terminal domain of arginine repressor
55257 4 113 RBP11-like subunits of RNA polymerase
55261 3 128 GAD domain
55267 3 69 tRNA-intron endonuclease N-terminal domain-like
55271 2 116 DNA repair protein MutS, domain I
55277 2 70 GYF domain
55282 2 160 Ribosomal protein L5
55287 1 72 RPB5-like RNA polymerase subunit
55298 5 123 YjgF-like
55307 5 146 Tubulin C-terminal domain-like
55315 7 105 L30e-like
55326 5 171 PurM N-terminal domain-like
55331 9 108 Tautomerase/MIF
55347 24 143 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
55383 1 86 Copper amine oxidase, domain N
55387 4 116 Frataxin/Nqo15-like
55394 2 228 Bactericidal permeability-increasing protein, BPI
55399 1 107 Subtilisin inhibitor
55405 3 126 RNA bacteriophage capsid protein
55418 3 205 eIF4e-like
55424 12 115
55447 5 111
55455 2 78 SRF-like
55464 5 144 Origin of replication-binding domain, RBD-like
55469 10 212 FMN-dependent nitroreductase-like
55481 1 138 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
55486 18 226 Metalloproteases ("zincins"), catalytic domain
55545 7 135 beta-N-acetylhexosaminidase-like domain
55550 21 108 SH2 domain
55594 3 87 HPr-like
55604 1 77 Glucose permease domain IIB
55608 12 115 Homing endonucleases
55620 12 150 Tetrahydrobiopterin biosynthesis enzymes-like
55637 1 101 Cell cycle regulatory proteins
55648 1 165 beta-lactamase-inhibitor protein, BLIP
55653 1 94 Ribosomal protein L9 C-domain
55658 2 49 L9 N-domain-like
55666 3 94 Ribonuclease PH domain 2-like
55671 1 104 Regulatory factor Nef
55676 2 209 CytB endotoxin-like
55681 19 298 Class II aaRS and biotin synthetases
55711 3 113 Subdomain of clathrin and coatomer appendage domain
55718 4 124 Sterol carrier protein, SCP
55729 48 157
55729 48 157 Acyl-CoA N-acyltransferases (Nat)
55753 14 124 Actin depolymerizing proteins
55770 3 130 Profilin (actin-binding protein)
55781 5 168 GAF domain-like
55785 8 114 PYP-like sensor domain (PAS domain)
55797 4 164 PR-1-like
55804 4 186 Phoshotransferase/anion transport protein
55811 29 161 Nudix
55816 1 188 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
55821 5 205 YrdC/RibB
55826 3 154 YbaK/ProRS associated domain
55831 3 261 Thymidylate synthase/dCMP hydroxymethylase
55846 8 167 N-acetylmuramoyl-L-alanine amidase-like
55856 5 91 Cytochrome b5-like heme/steroid binding domain
55869 1 77 DNA topoisomerase I domain
55874 9 200 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
55890 1 168 Sporulation response regulatory protein Spo0B
55895 7 204 Ribonuclease Rh-like
55904 1 161 Ornithine decarboxylase C-terminal domain
55909 11 344 Pentein
55920 7 249 Creatinase/aminopeptidase
55945 5 99 TATA-box binding protein-like
55957 3 116 Phosphoglucomutase, C-terminal domain
55961 22 187 Bet v1-like
55979 22 118 DNA clamp
56003 5 631 Molybdenum cofactor-binding domain
56014 2 158 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
56019 1 196 The spindle assembly checkpoint protein mad2
56024 10 205 Phospholipase D/nuclease
56029 3 108 Monooxygenase (hydroxylase) regulatory protein
56042 6 162 PurM C-terminal domain-like
56047 2 128 Ribosomal protein S8
56053 4 84 Ribosomal protein L6
56059 14 215 Glutathione synthetase ATP-binding domain-like
56091 8 238 DNA ligase/mRNA capping enzyme, catalytic domain
56112 37 294 Protein kinase-like (PK-like)
56176 10 201 FAD-binding domain
56194 2 126 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
56199 1 316 Methenyltetrahydromethanopterin cyclohydrolase
56204 2 362 Hect, E3 ligase catalytic domain
56209 1 193 Nitrile hydratase alpha chain
56214 3 116 4'-phosphopantetheinyl transferase
56219 9 266 DNase I-like
56228 1 210 Aldehyde ferredoxin oxidoreductase, N-terminal domain
56235 26 221 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
56266 2 370 DmpA/ArgJ-like
56271 2 234 Pyruvoyl-dependent histidine and arginine decarboxylases
56276 3 244 S-adenosylmethionine decarboxylase
56281 19 249 Metallo-hydrolase/oxidoreductase
56300 16 264 Metallo-dependent phosphatases
56317 4 275 Carbon-nitrogen hydrolase
56322 6 437 ADC synthase
56327 13 166 LDH C-terminal domain-like
56349 7 212 DNA breaking-rejoining enzymes
56366 1 126 SMAD MH1 domain
56371 9 254 Ribosome inactivating proteins (RIP)
56399 3 219 ADP-ribosylation
56420 5 171 Peptide deformylase
56425 4 131 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
56436 21 130 C-type lectin-like
56487 2 111 SRCR-like
56491 1 96 A heparin-binding domain
56496 3 225 Fibrinogen C-terminal domain-like
56502 1 306 gp120 core
56507 2 262 Methionine synthase activation domain-like
56512 2 383 Nitric oxide (NO) synthase oxygenase domain
56519 2 135 Penicillin binding protein dimerisation domain
56524 2 254 Oxidoreductase molybdopterin-binding domain
56529 6 238 FAH
56534 2 290 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
56542 2 274 Substrate-binding domain of HMG-CoA reductase
56548 1 311 Conserved core of transcriptional regulatory protein vp16
56553 2 126 Insert subdomain of RNA polymerase alpha subunit
56558 1 208 Baseplate structural protein gp11
56563 1 280 Major capsid protein gp5
56747 4 264 Prim-pol domain
63411 20 218 LuxS/MPP-like metallohydrolase
63763 3 94 SAND domain-like
64210 1 58 Head-to-tail joining protein W, gpW
64234 1 138 Photosystem I subunit PsaD
64263 1 105 Prokaryotic ribosomal protein L17
64268 5 129 PX domain
64288 2 161 Chorismate lyase-like
64307 3 86 SirA-like
64356 5 137 SNARE-like
64376 1 94 YlxR-like
64383 1 139 Cell-division protein ZipA, C-terminal domain
64397 2 232 Hsp33 domain
64438 3 256 CNF1/YfiH-like putative cysteine hydrolases
64449 1 123 YopH tyrosine phosphatase N-terminal domain
64465 1 365 Outer capsid protein sigma 3
64496 2 82
64586 3 69 C-terminal domain of ProRS
68930 1 104 Protein-L-isoaspartyl O-methyltransferase, C-terminal domain
69635 9 123 Type III secretory system chaperone
69645 3 150 Arp2/3 complex subunits
69652 1 108 DNA-binding C-terminal domain of the transcription factor MotA
69687 1 85 Integrin beta tail domain
69695 3 102 SRP19
69705 2 115 Transcription factor NusA, N-terminal domain
69721 1 111 DsrC, the gamma subunit of dissimilatory sulfite reductase
69737 2 68 Urease metallochaperone UreE, C-terminal domain
69742 1 143 Glutamyl tRNA-reductase catalytic, N-terminal domain
69754 1 112 Ribosome binding protein Y (YfiA homologue)
69761 1 83 GTP cyclohydrolase I feedback regulatory protein, GFRP
69765 2 152 IpsF-like
69786 2 106 YggU-like
69796 1 219 Thymidylate synthase-complementing protein Thy1
69819 2 132 MTH1598-like
69848 1 100 LCCL domain
69864 2 242 Argininosuccinate synthetase, C-terminal domain
74653 3 101 TolA/TonB C-terminal domain
75347 1 170 Rotavirus NSP2 fragment, C-terminal domain
75399 2 214 Plakin repeat
75404 1 163 VSV matrix protein
75412 1 88 Hypothetical protein MTH1880
75420 1 90 YhbC-like, N-terminal domain
75445 2 71 D-ribose-5-phosphate isomerase (RpiA), lid domain
75471 2 96 YhbY-like
75500 1 103 Putative transcriptional regulator TM1602, C-terminal domain
75516 1 165 Pheromone-binding domain of LuxR-like quorum-sensing transcription factors
75553 1 161 Smc hinge domain
75569 1 202 Archaeal IMP cyclohydrolase PurO
75574 1 143 Rotavirus NSP2 fragment, N-terminal domain
81271 4 69 TGS-like
81301 13 182 Nucleotidyltransferase
81606 2 262 PP2C-like
81660 4 170 Metal cation-transporting ATPase, ATP-binding domain N
82602 1 135 Nuclease A inhibitor (NuiA)
82607 1 85 YbaB-like
82649 5 129 SufE/NifU
82653 1 81 Probable GTPase Der, C-terminal domain
82657 2 105 BolA-like
82671 1 132 SEA domain
82679 2 110 N-utilization substance G protein NusG, N-terminal domain
82689 1 101 Mechanosensitive channel protein MscS (YggB), C-terminal domain
82693 4 101 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
82697 3 79 PurS-like
82704 3 88 AlbA-like
82708 3 91 R3H domain
82714 2 90 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
82754 2 142 C-terminal, gelsolin-like domain of Sec23/24
82771 1 97 GIY-YIG endonuclease
82784 5 136 OsmC-like
82808 1 115 Replication modulator SeqA, C-terminal DNA-binding domain
82829 2 90 MesJ substrate recognition domain-like
88798 2 73 N-terminal, heterodimerisation domain of RBP7 (RpoE)
88802 4 98 Pre-PUA domain
88874 1 198 Receptor-binding domain of short tail fibre protein gp12
89807 1 64 Flavin-binding protein dodecin
89811 1 64 Amyloid beta a4 protein copper binding domain (domain 2)
89817 1 144 Mago nashi protein
89837 1 101 Doublecortin (DC)
89872 2 128 Inhibitor of vertebrate lysozyme, Ivy
89890 1 94 Proguanylin
89895 2 94 FYSH domain
89915 1 122 DNA-binding protein Tfx
89919 2 98 Ribosome-binding factor A, RbfA
89942 1 162 eEF1-gamma domain
89946 1 132 Hypothetical protein VC0424
89957 6 109 MTH1187/YkoF-like
89963 2 81 YajQ-like
89975 1 105 Hypothetical protein Yml108w
90002 1 95 Hypothetical protein YjiA, C-terminal domain
90064 1 146 Hypothetical protein TM0875
90073 1 158 GCM domain
100879 5 105 Lesion bypass DNA polymerase (Y-family), little finger domain
100966 1 52 Translation initiation factor 2 beta, aIF2beta, N-terminal domain
102735 1 117 Trigger factor ribosome-binding domain
102741 1 76 Obg GTP-binding protein C-terminal domain
102816 1 107 Putative dsDNA mimic
102824 2 100 Colicin D/E5 nuclease domain
102829 1 90 Cell division protein ZapA-like
102848 1 102 NSFL1 (p97 ATPase) cofactor p47, SEP domain
102860 1 101 mRNA decapping enzyme DcpS N-terminal domain
102875 1 93 Chromosomal protein MC1
102886 2 270 Coproporphyrinogen III oxidase
102891 1 97 Hypothetical protein Ta1206
103007 1 98 Hypothetical protein TT1725
103025 4 281 Folate-binding domain
103032 1 254 Hypothetical protein YwqG
103039 2 178 CheC-like
103054 1 74 General secretion pathway protein M, EpsM
103063 1 60 Hypothetical protein YoaG
103068 3 87 Nucleocapsid protein dimerization domain
103084 1 118 Holliday junction resolvase RusA
103088 2 123 OmpA-like
103107 1 139 Hypothetical protein c14orf129, hspc210
103111 1 132 Activator of Hsp90 ATPase, Aha1
103145 1 117 Tombusvirus P19 core protein, VP19
103165 1 159 Ta1353-like
103190 3 135 Sensory domain-like
103196 4 118 Roadblock/LC7 domain
103239 1 78 MoaD-related protein, C-terminal domain
103243 1 102 Kinase associated domain 1, KA1
103247 2 126 TT1751-like
103256 1 140 Hypothetical protein TM0160
103263 3 327 Chorismate synthase, AroC
103277 1 159 Hypothetical protein HI1480
103359 1 236 Suppressor of Fused, N-terminal domain
103365 1 480 Hypothetical protein PH1602
103370 1 141 NinB
110783 1 91 Hypothetical protein MTH677
110814 1 83 TmoB-like
110836 1 79 Hypothetical protein SAV1430
110849 2 158 ParB/Sulfiredoxin
110857 3 126 BtrG-like
110916 1 112 Peptidyl-tRNA hydrolase domain-like
110921 1 114 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
110942 1 112 HSP90 C-terminal domain
110993 2 103 eIF-2-alpha, C-terminal domain
110997 1 77 Sporulation related repeat
111006 1 125 Dystroglycan, domain 2
111038 3 135 YjbQ-like
111057 1 94 Hypothetical protein PF0899
111064 1 144 Hut operon positive regulatory protein HutP
111069 1 157 Hypothetical protein yfbM
111074 1 103 Bacillus phage protein
111126 2 174 Ligand-binding domain in the NO signalling and Golgi transport
111148 1 75 YggX-like
111171 1 119 Rbstp2229 protein
111249 1 359 Sulfolobus fructose-1,6-bisphosphatase-like
111265 1 149 Hemolytic lectin CEL-III, C-terminal domain
111278 1 189 SSo0622-like
111283 2 432 Putative modulator of DNA gyrase, PmbA/TldD
116726 2 93 TrkA C-terminal domain-like
116734 5 193 DNA methylase specificity domain
117773 1 99 GTF2I-like repeat
117778 1 52 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain
117782 1 103 YbjQ-like
117839 1 110 WWE domain
117856 2 270 AF0104/ALDC/Ptd012-like
117892 1 143 Band 7/SPFH domain
117916 4 86 Fe-S cluster assembly (FSCA) domain-like
117987 2 94 CRISPR-associated protein
117991 1 87 YbeD-like
118001 1 71 YehU-like
118010 1 94 Hypothetical protein TM1457
118104 1 157 RalF, C-terminal domain
118116 1 180 DNA mismatch repair protein MutL
118173 1 111 Phosphoprotein M1, C-terminal domain
142877 2 211 EndoU-like
142887 1 55 PhtA domain-like
142897 1 63 TFB5-like
142906 2 124 YjbR-like
142913 2 184 YktB/PF0168-like
142921 1 126 WGR domain-like
142984 1 84 Nqo1 middle domain-like
143011 3 86 RelE-like
143021 1 120 Ns1 effector domain-like
143026 2 73 Kinetochore globular domain
143034 1 64 L35p-like
143076 1 155 Coronavirus NSP8-like
143081 4 218 BB1717-like
143100 1 70 TTHA1013-like
143113 1 283 NAP-like
143120 2 66 YefM-like
143212 1 83 Rv2632c-like
143243 1 191 Nqo5-like
143410 1 113 DOPA-like
143414 2 98 CcmK-like
143422 2 130 Transposase IS200-like
143430 1 82 TTP0101/SSO1404-like
143437 3 147 THUMP domain-like
143447 1 201 AMMECR1-like
143456 3 179 VC0467-like
143469 1 83 ImmE5-like
143477 1 124 TM1622-like
143492 1 301 Prenyltransferase-like
143503 1 99 PUG domain-like
143517 1 158 TRCF domain-like
143548 2 136 Serine metabolism enzymes domain
143555 1 147 FwdE-like
143560 2 114 MK0786-like
143567 1 75 YkuJ-like
143575 1 85 GAS2 domain-like
143579 1 94 GK1464-like
143587 1 183 SARS receptor-binding domain-like
143592 1 123 TTHA1528-like
143597 1 201 YojJ-like
143602 2 110 STIV B116-like
143631 1 304 ApbE-like
143724 2 194 PHP14-like
143737 1 115 YeeU-like
143744 1 142 GlcG-like
143749 2 132 Phage tail protein-like
143791 1 120 DUSP-like
143800 2 79 L28p-like
143842 1 198 YwmB-like
143847 3 107 XisI-like
143856 1 96 DeoB insert domain-like
143865 1 220 CorA soluble domain-like
143870 1 136 PF0523-like
143875 1 100 ERH-like
143880 1 84 NE0471 N-terminal domain-like
143885 1 100 RGC domain-like
143968 1 161 UbiD C-terminal domain-like
143975 1 322 IlvD/EDD N-terminal domain-like
143985 1 122 L,D-transpeptidase pre-catalytic domain-like
143990 1 160 YbiA-like
143995 1 88 AF2331-like
144000 1 433 Oxysterol-binding protein-like
144005 1 118 ORC1-binding domain
144010 1 248 CofE-like
144015 1 187 Peptidoglycan deacetylase N-terminal noncatalytic region
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
56574 11 369 Serpins
56596 1 305 Replication terminator protein (Tus)
56601 24 299 beta-lactamase/transpeptidase-like
56634 3 518 Heme-dependent catalase-like
56645 10 237 Acyl-CoA dehydrogenase NM domain-like
56655 7 308 Carbohydrate phosphatase
56672 6 504 DNA/RNA polymerases
56712 3 569 Prokaryotic type I DNA topoisomerase
56719 2 578 Type II DNA topoisomerase
56726 1 289 DNA topoisomerase IV, alpha subunit
56731 2 251 DNA primase core
56741 1 221 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
56752 4 303 D-aminoacid aminotransferase-like PLP-dependent enzymes
56762 3 463 HydB/Nqo4-like
56770 2 206 HydA/Nqo6-like
56796 7 370 Dehydroquinate synthase-like
56801 3 511 Acetyl-CoA synthetase-like
56808 3 216 Ribosomal protein L1
56815 2 552 Sec1/munc18-like (SM) proteins
56826 1 249 Upper collar protein gp10 (connector protein)
64518 1 395 Phase 1 flagellin
69903 1 154 NSP3 homodimer
69908 1 641 Membrane penetration protein mu1
75615 2 110 Siroheme synthase middle domains-like
75620 2 336 Release factor
75625 2 230 YebC-like
75632 1 276 Cullin homology domain
81298 1 498 Adenylylcyclase toxin (the edema factor)
82856 1 651 L-A virus major coat protein
90096 2 272 Subunits of heterodimeric actin filament capping protein Capz
103378 1 461 2-methylcitrate dehydratase PrpD
103383 1 290 Antivirulence factor
103388 1 272 Virulence-associated V antigen
103409 1 189 39 kda initiator binding protein, IBP39, C-terminal domains
103417 1 542 Major capsid protein VP5
111304 1 199 Recombination protein RecR
111321 3 294 AF1104-like
111326 1 554 Urocanase
111331 2 258 NAD kinase
111337 1 280 QueA-like
111342 1 282 CbiD-like
111347 1 330 Rap/Ran-GAP
118196 1 183 YaeB-like
118203 1 364 Vacuolar ATP synthase subunit C
118208 1 1029 Viral ssDNA binding protein
144020 1 285 FdhE-like
144052 2 405 Thermophilic metalloprotease-like
144059 1 259 ImpE-like
144064 2 248 Heme iron utilization protein-like
144074 2 124 E2F-DP heterodimerization region
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
56837 2 186 Colicin
56845 1 178 Diphtheria toxin, middle domain
56849 3 238 delta-Endotoxin (insectocide), N-terminal domain
56854 9 164 Bcl-2 inhibitors of programmed cell death
56864 1 143 Exotoxin A, middle domain
56918 6 49 Light-harvesting complex subunits
56925 4 147 OMPA-like
56931 1 253 Outer membrane phospholipase A (OMPLA)
56935 6 349 Porins
56954 2 440 Outer membrane efflux proteins (OEP)
56959 2 278 Leukocidin-like
56973 2 321 Aerolisin/ETX pore-forming domain
56978 1 471 Perfringolysin
56983 2 297 Viral glycoprotein, central and dimerisation domains
56988 1 665 Anthrax protective antigen
69917 2 273 OMPT-like
69922 1 265 Head and neck region of the ectodomain of NDV fusion glycoprotein
81321 5 250 Family A G protein-coupled receptor-like
81324 3 100 Voltage-gated potassium channels
81327 1 81 Small-conductance potassium channel
81330 1 109 Gated mechanosensitive channel
81333 1 79 F1F0 ATP synthase subunit C
81336 1 142 F1F0 ATP synthase subunit A
81338 3 240 Aquaporin-like
81340 1 444 Clc chloride channel
81343 5 149 Fumarate reductase respiratory complex transmembrane subunits
81345 1 313 ABC transporter involved in vitamin B12 uptake, BtuC
81406 1 144 Mitochondrial cytochrome c oxidase subunit IV
81411 1 83 Mitochondrial cytochrome c oxidase subunit VIa
81415 1 72 Mitochondrial cytochrome c oxidase subunit VIc
81419 1 58 Mitochondrial cytochrome c oxidase subunit VIIa
81423 1 49 Mitochondrial cytochrome c oxidase subunit VIIb
81427 1 46 Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)
81431 1 43 Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX)
81442 3 521 Cytochrome c oxidase subunit I-like
81452 2 222 Cytochrome c oxidase subunit III-like
81464 3 93 Cytochrome c oxidase subunit II-like, transmembrane region
81469 1 42 Bacterial aa3 type cytochrome c oxidase subunit IV
81473 1 33 Bacterial ba3 type cytochrome c oxidase subunit IIa
81483 2 291 Bacterial photosystem II reaction centre, L and M subunits
81490 3 32 Photosystem II reaction centre subunit H, transmembrane region
81496 1 46 Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor
81502 4 50 ISP transmembrane anchor
81508 2 83 Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81514 2 44 Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81518 1 51 Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81524 2 112 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81531 2 70 Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81536 1 141 Subunit III of photosystem I reaction centre, PsaF
81540 1 38 Subunit VIII of photosystem I reaction centre, PsaI
81544 1 41 Subunit IX of photosystem I reaction centre, PsaJ
81548 1 31 Subunit XII of photosystem I reaction centre, PsaM
81552 1 29 Subunit PsaX of photosystem I reaction centre
81558 1 740 Photosystem I subunits PsaA/PsaB
81563 1 46 Photosystem I reaction center subunit X, PsaK
81568 1 151 Photosystem I reaction center subunit XI, PsaL
81573 1 61 F1F0 ATP synthase subunit B, membrane domain
81597 1 45 Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
81648 2 138 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
81665 1 472 Calcium ATPase, transmembrane domain M
82861 1 86 Mechanosensitive channel protein MscS (YggB), transmembrane region
82866 2 210 Multidrug efflux transporter AcrB transmembrane domain
90112 2 127 Neurotransmitter-gated ion-channel transmembrane pore
90123 2 300 ABC transporter transmembrane region
103431 1 45 Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor
103436 2 32 PetL subunit of the cytochrome b6f complex
103441 2 33 PetM subunit of the cytochrome b6f complex
103446 1 30 PetG subunit of the cytochrome b6f complex
103451 1 31 PetN subunit of the cytochrome b6f complex
103456 1 56 Preprotein translocase SecE subunit
103460 1 32 Sec-beta subunit
103464 1 36 Oligosaccharyltransferase subunit ost4p
103473 2 426 MFS general substrate transporter
103481 1 106 Multidrug resistance efflux transporter EmrE
103486 1 312 V-type ATP synthase subunit C
103491 1 410 Preprotein translocase SecY subunit
103501 1 223 Respiratory nitrate reductase 1 gamma chain
103506 1 292 Mitochondrial carrier
103511 1 218 Chlorophyll a-b binding protein
103515 1 279 Autotransporter
111352 1 372 Ammonium transporter
111357 1 66 Mitochondrial ATP synthase coupling factor 6
111364 1 251 Tsx-like channel
111369 1 237 HlyD-like secretion proteins
111379 1 270 VP4 membrane interaction domain
111384 1 84 OmpH-like
118215 1 405 Proton glutamate symport protein
118220 1 132 Connexin43
144083 1 50 Magnesium transport protein CorA, transmembrane region
144091 2 186 Rhomboid-like
superfamily
code |
Num. of
members |
Average
size |
Superfamily
name |
56994 3 49 Insulin-like
57007 1 48 Heat-stable enterotoxin B
57011 1 54 Neurotoxin B-IV
57016 3 42 Plant lectins/antimicrobial peptides
57027 3 32 Plant inhibitors of proteinases and amylases
57038 3 32 Cyclotides
57048 3 36 Gurmarin-like
57055 1 46 Agouti-related protein
57059 13 36 omega toxin-like
57095 26 45 Scorpion toxin-like
57180 1 36 Cellulose-binding domain
57184 2 151 Growth factor receptor domain
57190 4 41 Colipase-like
57196 23 45 EGF/Laminin
57243 2 26 Bromelain inhibitor VI (cysteine protease inhibitor)
57247 2 66 Bowman-Birk inhibitor, BBI
57256 1 47 Elafin-like
57262 5 52 Leech antihemostatic proteins
57277 1 30 Granulin repeat
57283 2 33 PMP inhibitors
57288 2 51 Midkine
57296 1 40 Amb V allergen
57302 14 71 Snake toxin-like
57362 9 59 BPTI-like
57392 13 40 Defensin-like
57414 3 89 Hairpin loop containing domain-like
57419 1 27 Neurotoxin III (ATX III)
57424 6 44 LDL receptor-like module
57429 2 46 Crambin-like
57440 6 74 Kringle-like
57492 2 52 Trefoil
57501 10 102 Cystine-knot cytokines
57535 27 63 Complement control module/SCR domain
57546 3 43 Crisp domain-like
57552 2 58 Blood coagulation inhibitor (disintegrin)
57561 1 124 Methylamine dehydrogenase, L chain
57567 4 59 Serine protease inhibitors
57581 3 71 TB module/8-cys domain
57586 18 43 TNF receptor-like
57593 1 55 Heparin-binding domain from vascular endothelial growth factor
57598 1 51 Antifungal protein (AGAFP)
57603 6 50 FnI-like domain
57610 2 86 Thyroglobulin type-1 domain
57615 1 50 Type X cellulose binding domain, CBDX
57620 1 61 Carboxypeptidase inhibitor
57625 2 54 Invertebrate chitin-binding proteins
57630 3 33 GLA-domain
57642 1 47 Cholecystokinin A receptor, N-domain
57647 1 45 HIV-1 VPU cytoplasmic domain
57652 5 72 HIPIP (high potential iron protein)
57662 1 109 Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
57667 42 34 C2H2 and C2HC zinc fingers
57701 5 45 Zn2/Cys6 DNA-binding domain
57716 22 35 Glucocorticoid receptor-like (DNA-binding domain)
57756 4 34 Retrovirus zinc finger-like domains
57770 1 35 Methionyl-tRNA synthetase (MetRS), Zn-domain
57774 3 35 Microbial and mitochondrial ADK, insert "zinc finger" domain
57783 13 61 Zinc beta-ribbon
57798 1 159 Casein kinase II beta subunit
57802 6 56 Rubredoxin-like
57821 1 71 Hypothetical protein MTH1184
57825 2 54 Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
57829 6 64 Zn-binding ribosomal proteins
57840 1 37 Ribosomal protein L36
57845 1 39 B-box zinc-binding domain
57850 10 78 RING/U-box
57863 2 140 ArfGap/RecO-like zinc finger
57868 9 37 Metallothionein
57879 1 42 Zinc domain conserved in yeast copper-regulated transcription factors
57884 1 92 Ada DNA repair protein, N-terminal domain (N-Ada 10)
57889 5 59 Cysteine-rich domain
57903 11 72 FYVE/PHD zinc finger
57917 2 106 Zn-binding domains of ADDBP
57924 4 108 Inhibitor of apoptosis (IAP) repeat
57933 2 91 TAZ domain
57938 2 76 DnaJ/Hsp40 cysteine-rich domain
63393 2 54 RNA polymerase subunits
64546 1 41 Satiety factor CART (cocaine and amphetamine regulated transcript)
64571 1 46 Cellulose docking domain, dockering
69964 1 51 Pheromone ER-23
75689 1 36 Zinc-binding domain of translation initiation factor 2 beta
82895 1 54 TSP-1 type 1 repeat
82910 1 110 Apical membrane antigen 1
82919 2 76 Zn-finger domain of Sec23/24
82927 1 52 Cysteine-rich DNA binding domain, (DM domain)
90148 1 24 DPY module
90183 1 58 Mollusk pheromone
90188 1 37 Somatomedin B domain
90193 1 35 Notch domain
90209 4 41 Ran BP2/NZF zinc finger-like
90229 3 40 CCCH zinc finger
90234 1 31 Zinc finger domain of DNA polymerase-alpha
100895 3 59 Kazal-type serine protease inhibitors
100897 2 54 Plant proteinase inhibitors
103565 1 64 Bubble protein
103575 3 54 Plexin repeat
103580 1 60 Necrosis inducing protein 1, NIP1
103589 1 24 Mini-collagen I, C-terminal domain
103612 1 81 SBT domain
103623 1 36 Hypothetical protein Ta0289 C-terminal domain
103637 1 48 CCHHC domain
103642 1 24 Sec-C motif
103647 1 124 TSP type-3 repeat
111388 1 50 Pollen allergen ole e 6
111418 1 119 Hormone receptor domain
111423 1 89 Resistin
111430 1 121 YAP1 redox domain
116738 1 27 NADH pyrophosphatase intervening domain
118251 1 80 Variant surface glycoprotein MITAT 1.2, VSG 221, C-terminal domain
118290 1 71 WRKY DNA-binding domain
118310 2 86 AN1-like Zinc finger
118352 2 60 HSP33 redox switch-like
118359 1 86 Expressed protein At2g23090/F21P24.15
144122 2 66 Tim10-like
144129 1 92 Vanabin-like
144206 1 66 NOB1 zinc finger-like
144210 2 54 Nop10-like SnoRNP
144217 2 76 CSL zinc finger
144232 3 50 HIT/MYND zinc finger-like
144246 1 123 Coronavirus NSP10-like
144251 1 32 Viral leader polypeptide zinc finger
144256 1 83 TSP9-like
