PASS2
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Superfamily Details

Superfamily summary
Superfamily Name:  Phosphoenolpyruvate/pyruvate domain
Class Name:  Alpha and beta proteins (a/b)
Fold Name:  TIM beta/alpha-barrel
Number of Members:  13
Average Size: 
Members
SCOP ID Name Source
d2g50a2 Pyruvate kinase, N-terminal domain Rabbit (Oryctolagus cuniculus) [TaxId: 9986]
d1kbla1 Pyruvate phosphate dikinase, C-terminal domain Clostridium symbiosum [TaxId: 1512]
d1jqna- Phosphoenolpyruvate carboxylase Escherichia coli [TaxId: 562]
d1s2wa- Phosphoenolpyruvate mutase Blue mussel (Mytilus edulis) [TaxId: 6550]
d1muma- 2-methylisocitrate lyase Escherichia coli [TaxId: 562]
d1dqua- Isocitrate lyase Aspergillus nidulans [TaxId: 162425]
d1f61a- Isocitrate lyase Mycobacterium tuberculosis [TaxId: 1773]
d1dxea- 2-dehydro-3-deoxy-galactarate aldolase Escherichia coli [TaxId: 562]
d1izca- Macrophomate synthase Macrophoma commelinae [TaxId: 108330]
d1sgja- Citrate lyase, beta subunit Deinococcus radiodurans [TaxId: 1299]
d1u5ha- Citrate lyase, beta subunit Mycobacterium tuberculosis [TaxId: 1773]
d1m3ua- Ketopantoate hydroxymethyltransferase PanB Escherichia coli [TaxId: 562]
d2p10a1 Uncharacterized protein Mll9387 Mesorhizobium loti [TaxId: 381]

Alignment Based On Similarities In Structural Features using Comparer

                             10        20        30        40        50  
d1dqua-  (   2 )                                                      
d1dxea-  (   4 )                                                      
d1f61a-  (   1 )                                                      
d1izca-  (   2 )                                                      
d1jqna-  (   4 )    qysaLrsnvsmLgkVLgetIkdalgehilerVetIrkLSksSragndanr
d1kbla1  ( 510 )                                                      
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (   4 )                                                      
d1u5ha-  (   1 )                                                      
d2g50a2  (  12 )                                                      
d2p10a1  (   8 )                                                      
                                                                      

                             60        70        80        90        100 
d1dqua-  (   2 )                                                      
d1dxea-  (   4 )                                                      
d1f61a-  (   1 )                                                      
d1izca-  (   2 )                                                      
d1jqna-  (  54 )    qeLlttLqnLsndeLlpVArAFsqfLnlANtAEqYhsISpkGeaasnpev
d1kbla1  ( 510 )                                                      
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (   4 )                                                      
d1u5ha-  (   1 )                                                      
d2g50a2  (  12 )                                                      
d2p10a1  (   8 )                                                      
                                                                      

                             110       120       130       140       150 
d1dqua-  (   2 )                                                      
d1dxea-  (   4 )                                                      
d1f61a-  (   1 )                                                      
d1izca-  (   2 )                                                      
d1jqna-  ( 104 )    IartLrkLknqpelsedtIkkaVesLsLeLVLtahpTeitrrtlihkmve
d1kbla1  ( 510 )                                                      
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (   4 )                                                      
d1u5ha-  (   1 )                                                      
d2g50a2  (  12 )                                                      
d2p10a1  (   8 )                                                      
                                                                      

                             160       170       180       190       200 
d1dqua-  (   2 )                                                      
d1dxea-  (   4 )                                                      
d1f61a-  (   1 )                                                      
d1izca-  (   2 )                                             aksyseqpe
d1jqna-  ( 154 )    vnacLkqLdnkdiadyehnqlmrrLrqLIaqsWhtdeIrklrpsPvdeAk
d1kbla1  ( 510 )                                                      
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (   4 )                                                      
d1u5ha-  (   1 )                                                      
d2g50a2  (  12 )                                                      
d2p10a1  (   8 )                                                      
                                                                      

                             210       220       230       240       250 
d1dqua-  (   2 )                                                      
d1dxea-  (   4 )               dvFpnkFkaaLaak-----------qvqiGCWSal--sn
d1f61a-  (   1 )                                                      
d1izca-  (  11 )    lhakApyrSamltyPGnLrqALkdAma------dpskTLmGvaHgi--ps
d1jqna-  ( 204 )    wGfaVVenSLwqGVPnYLreLneqLeenLgykLpvefVPVrFTswMGGdR
d1kbla1  ( 510 )     ietqeasvsgsfer--iMvwAdkfr----------tLkVrTnAd----t
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (   4 )                                   ppa--lLrSVLfApG--nr
d1u5ha-  (   1 )                                   MnlraAgpGWLfCpA--da
d2g50a2  (  12 )         iqtqqlhAamAdtfleHkcrldidSapitarnTgIICTIgpaSrs
d2p10a1  (   8 )                                                      
                                                                      

                             260       270       280       290       300 
d1dqua-  (   2 )                                                      
d1dxea-  (  30 )    -------pisTevlGlagfdWL-VLDGehApNd-----------------
d1f61a-  (   1 )                                                      
d1izca-  (  53 )    -------tfvTkvlAatkpdFV-wIdvehgmFn-----------------
d1jqna-  ( 254 )    DgNpnVtAdiTrhVlllSrw------kAtdLFlkdIqvLvseLsmveAtp
d1kbla1  ( 543 )    -------pedTlnAvklgAeGIGlCrTehMFfea----------------
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (  19 )    -------adlIakLprsaPdAV-VIDLedaVp------------------
d1u5ha-  (  18 )    -------peaFaaaaaa-AdVV-ILDLEdgVa------------------
d2g50a2  (  57 )    -------vetLkeMIksgMnvA-rMnFshg--------------------
d2p10a1  (   8 )                                                      
                                                                      

                             310       320       330       340       350 
d1dqua-  (   2 )                                                      
d1dxea-  (  55 )    --------------------------------------------------
d1f61a-  (   1 )                                                      
d1izca-  (  78 )    --------------------------------------------------
d1jqna-  ( 298 )    eLlalVgeeGaaePYrylMknLrsrLmaTqawLearlkgeelpkpeglLt
d1kbla1  ( 570 )    -----------------------drimkIrkMILsd--------------
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (  43 )    --------------------------------------------------
d1u5ha-  (  41 )    --------------------------------------------------
d2g50a2  (  79 )    --------------------------------------------------
d2p10a1  (   8 )                                                      
                                                                      

                             360       370       380       390       400 
d1dqua-  (   2 )                                                      
d1dxea-  (  55 )    ------istFipQLmaLk--------------------gsa--SapVVrV
d1f61a-  (   1 )                                                      
d1izca-  (  78 )    ------rleLhdAIhaAQ----------hhS-------eGr--SLVIVrV
d1jqna-  ( 348 )    qneeLwepLyaCyqSLqacgmgiiAngdLLdTLrrVkCFGvpLVrIDIrq
d1kbla1  ( 583 )    -sveareeALneLipfQk----------gdFkaMYkaLegrpMTVrYLdP
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (  43 )    ----gtaeaKaaArpvAh----------daardLiaaap---hlaVFVrV
d1u5ha-  (  41 )    ------eaqkpaArnALr----------dtpldpe---------rTVVrI
d2g50a2  (  79 )    -----theyHaeTIknVr----------tATesfasdpilyrpVaVALDT
d2p10a1  (   8 )                                                      
                                                                      

                             410       420       430       440       450 
d1dqua-  (   2 )    syieeedqrywdeVaaVknwwk-dsRWryTkrpftAeqIVakrgnlkiey
d1dxea-  (  77 )    ptne----------------------------------------------
d1f61a-  (   1 )        asvvgtpksaeqiqqewdtnpRwkdvtRtysAedVvalqgsvveeh
d1izca-  ( 103 )    pkhd----------------------------------------------
d1jqna-  ( 398 )    estrHteALGeLTrylgigdYeswseadkqaFLireLnskrpllprnwqP
d1kbla1  ( 622 )    PLheFVPhteeeqaeLAkn-mgltlaeVkakvdelhefnpmmghrGCrLa
d1m3ua-  (   3 )                                                      
d1muma-  (   3 )                                                      
d1s2wa-  (   4 )                                                      
d1sgja-  (  76 )    NaLh----------------------------------------------
d1u5ha-  (  66 )    naGg----------------------------------------------
d2g50a2  ( 114 )    kGpaVs--------------------------------------------
d2p10a1  (   8 )                                                      
                                                                      

                             460       470       480       490       500 
d1dqua-  (  51 )    p-SnvQAkkLwgiLernfknk--------eAsfTyG-CldptmVTqMAk-
d1dxea-  (  81 )    -------pviIkrLLdi-----------GFyNFLIPfVetkeeAelAvaS
d1f61a-  (  47 )    tlArrgAevLweqLhdl------------ewVnAlG-ALtGnmAvqqVra
d1izca-  ( 107 )    -------evsLstALdA-----------GAAGIVIPhVetveeVrefvke
d1jqna-  ( 448 )    saeTreVldTCqVIaeapq--------gSIAAYVISmAktpSdVLAVhLL
d1kbla1  ( 671 )    vtypEIAkMQTrAVMeAAIeVkeetgidivPeIMIPLVgekkeLkfVkdv
d1m3ua-  (   3 )           pttislLqkykqek--------krfATIT-AYdysfAklFade
d1muma-  (   3 )      lhSpGkaFraAltke------------nPLqIvG-TinanhAllaqra
d1s2wa-  (   4 )      kvkkttqLkqMLnsk------------dLefImE-AhnglsAriVqea
d1sgja-  (  80 )    ---spyFedDLsVLtp------------eLsGVVVPkLemgaEArqVaqm
d1u5ha-  (  70 )    ---tadqarDleaLagt-----------aYtTVMLPkAesaaqVieLa--
d2g50a2  ( 222 )    ----ekDiqDLkfGveq-----------dVdmVFASfIrkaaDVheVrki
d2p10a1  (   8 )      krptrseLvdrFqkkirag--------epiiggg-AGtglsAkseeag
                          aaaaaaaaaa               bbbb     aaaaaaaaa 

                             510       520       530       540       550 
d1dqua-  (  90 )    --------yldTVYVSGwQSSstaSstdepspdla-----------dYpm
d1dxea-  ( 113 )    TryppeGiRgvsvshrANmfg-tva-------dYfaqSnknITILVQIEs
d1f61a-  (  84 )    --------glkAIYLSGwQVAgdaNlsghtypdqs-----------lYpa
d1izca-  ( 139 )    MYygpigrrsfsp--wtFspgiadaSlfpndpyNvaTSnnHVCIIPQIEs
d1jqna-  ( 490 )    Lkeagig--------------------------------faMpVAPLFEt
d1kbla1  ( 721 )    VvevAeqVkkekgsd------------------------mqyhIGTMIEi
d1m3ua-  (  37 )    --------gLnvMlVGDsLGmtvq-----ghdsTl-----------pVtv
d1muma-  (  38 )    --------gyqAIYLsggGVAagsl----glpdlg-----------istl
d1s2wa-  (  39 )    --------gfkGIWGs--gLsvsa-----qlw------------------
d1sgja-  ( 115 )    Lqer----------------------------------slpLpILAGLEt
d1u5ha-  ( 104 )    ----------------------------------------prdVIALVEt
d2g50a2  ( 257 )    LgekGk----------------------------------nikIISkIEn
d2p10a1  (  47 )    --------didlIVIyNSGryragr--gslaGlla-----------ygnA
                                                                      

                             560       570       580       590       600 
d1dqua-  ( 121 )    nTVPn----kVnhLwmaQlfhdrkqr----------eermttpkdqrhkv
d1dxea-  ( 155 )    qqGvd----nVdaIAate-------gVdGIFVgpsdLAaalg-hl-----
d1f61a-  ( 115 )    nSVPq----vVrrINnaLqradqiak----------ie----------gd
d1izca-  ( 187 )    vkGve----nVdaIAaMp-------eIhGLmFgpgdYmidagldl-----
d1jqna-  ( 508 )    lddLnnAndvMtqLLnidwYrgliqgkQmVMIgysdSakd----------
d1kbla1  ( 747 )    prAAl----tAdaIAe---------eAefFSFgTndLTqmtfgfsrddAg
d1m3ua-  (  63 )    adIay----hTaaVrrGAp-------------------------------
d1muma-  (  65 )    ddVLt----dIrrItdvCs-------------------------------
d1s2wa-  (  65 )    tqvve----vLefMSdaSd-------------------------------
d1sgja-  ( 131 )    gaGVw----nAreIMeVp-------eVaWAYFgAedyttdlgg-krt---
d1u5ha-  ( 114 )    arGav----cAaeIAaad-------pTvGMMWgAedLiatlggsssrra-
d2g50a2  ( 273 )    heGvr----rFdeIle---------ASdGIMVargdLgieip--------
d2p10a1  (  77 )    nqiVv----dAreVlpvVr-------------------------------
                    aaaaa     aaaaa                                   

                             610       620       630       640       650 
d1dqua-  ( 157 )    anv-dYlrPIIAdAdtGhg-gltaVmkLTklFVer------GAAGIHIeD
d1dxea-  ( 188 )    -------------gna----shpdVqkaIqhIFnrAsah--gkpSGIlAp
d1f61a-  ( 141 )    tsvenWlAPIVAdGEaGfg-galnVyeLQkaLIaa------GVAGSHWED
d1izca-  ( 221 )    -------------ngalsgvphptfveAmtkFstAAqrn--gvPIFggAl
d1jqna-  ( 548 )    ---------------AgvMAASWAqYqaQdaLiktCekagIeLtLFHgrg
d1kbla1  ( 784 )    kfldsyykakiyesdPFarLdqtgVGqlVemAVkkGrqtrpgLkCGICGe
d1m3ua-  (  78 )    ------nCLLLADLPfmAYatpeqAfenAatVmra------gAnMVKIEg
d1muma-  (  80 )    -------lPLLVdAdiGfgssafnVarTVksMikA------gAAGLHIED
d1s2wa-  (  80 )    -------vPILldAdtgy-gnfnnArrlVrkLEdr------gVAGACLeD
d1sgja-  ( 166 )    ------------------pgG-leVlyARsqVAlaArlt--gVaALDIvV
d1u5ha-  ( 152 )    -----------------dgayrdvArhVrstIllaAsaf--grLALDAvH
d2g50a2  ( 302 )    ---------------------aekvflaQkmIIgrCnra--gkpVICAtq
d2p10a1  (  93 )    ------hTpVLAGVnGtdpf----vstfLreLkei------gFaGVQNfP
                                            aaaaaaaaaaa         bbb   

                             660       670       680       690       700 
d1dqua-  ( 199 )    Qapgtk------gkVLVpIseHinRLvaIRaqADiMgTDLLAIArTDSea
d1dxea-  ( 219 )    v---------------------eadArrYlew------gAtFVAvgs---
d1f61a-  ( 184 )    qlasekkcghlggkVLipTqqHirtLtsARlAAdvadVpTVVIArTDAea
d1izca-  ( 256 )    s---------------------vdmvpsLieq------gyrAIavqf---
d1jqna-  ( 583 )    gSiGrgg------------apAhaALlSqPpgSL----kGGLRVTEQGeM
d1kbla1  ( 834 )    HGGd------------------psSVefChkv------gLnYVSC-s---
d1m3ua-  ( 116 )    g------------------ewLveTVqmLter------avpVCGHLGL--
d1muma-  ( 117 )    qvga-krcghrpnkaIvskeeMvdrIraAvdAk--tdpdFVIMArTdAla
d1s2wa-  ( 116 )    klfg-------raqpLadieeFalkIkaCkdSQ--tdpdFCIVArVEAfi
d1sgja-  ( 195 )    taln-------------dpetFradAeqGral------gYsGKLCih---
d1u5ha-  ( 183 )    ldil-------------dvegLqeeArdAaav------gFdVTVCih---
d2g50a2  ( 329 )    MLesMikkpr-------ptraegsdVanAVld------gAdcIML-sgET
d2p10a1  ( 129 )    TvGlid--------------------------------------------
                                          aaaaaaaaa          bbbb     

                             710       720       730       740       750 
d1dqua-  ( 249 )    --A-tlItstidh--rDhpfIiGStnpdiqpLndlmvmaeqagkngaelq
d1dxea-  ( 239 )    -----------dlgvfrsat-----qkladtfkk                
d1f61a-  ( 234 )    --A-tLItsdvde--rDqpfitgertr-----------------------
d1izca-  ( 276 )    -----------dvwglsrlv-----hgslaqaras-------akqfag  
d1jqna-  ( 617 )    IrFKYgLpeiTvssLslYTg-----AILeanLlpppePkeswrrIMdeLs
d1kbla1  ( 856 )    -----------pfrVpiArl-----AAAqAalnn                
d1m3ua-  ( 140 )    ------tpqsvni--fggykvqGrg-------------------------
d1muma-  ( 164 )    --v-e---------------------------------------------
d1s2wa-  ( 165 )    --A-gw--------------------------------------------
d1sgja-  ( 223 )    -----------paQValAhe-----yFg                      
d1u5ha-  ( 211 )    -----------psQIpvVrk-----Aya-------------------a  
d2g50a2  ( 365 )    akGd-----ypleAVrmQhl-----iAreAeaamF-------hrklfe  
d2p10a1  ( 135 )    --------------------------------------------------
                                                                      

                             760       770       780       790       800 
d1dqua-  ( 294 )    aiedeWlakAglklFndaVvdaInnsplpnkkaaiekYltqskgksnlea
d1dxea-                                                               
d1f61a-  ( 256 )    --------------------------------------------------
d1izca-                                                               
d1jqna-  ( 662 )    viScdvYrgyVrenkdFvpYFrsATPeqelgkLpLgSrpggVeslraipW
d1kbla1                                                               
d1m3ua-  ( 157 )    --------------------------------------------------
d1muma-  ( 166 )    --------------------------------------------------
d1s2wa-  ( 168 )    --------------------------------------------------
d1sgja-                                                               
d1u5ha-                                                               
d2g50a2                                                               
d2p10a1  ( 135 )    --------------------------------------------------
                                                                      

                             810       820       830       840       850 
d1dqua-  ( 344 )    raiAkeiagtdiyFdweaPrtregyyrYqggtqCAinRAvaYAp-fAdLI
d1dxea-                                                               
d1f61a-  ( 256 )    ----------------------egfyrTkngiePCiaRAkaYAp-fADLI
d1izca-                                                               
d1jqna-  ( 718 )    ifAWTQNRLMLPaWLGAGtALqkVvedgkqseLeaMcr------------
d1kbla1                                                               
d1m3ua-  ( 157 )    ----------------------------deagdqllsdAlaLeaAgAqLL
d1muma-  ( 166 )    ------------------------------gldaAierAqaYveagAeML
d1s2wa-  ( 168 )    ------------------------------gldeAlkrAeaYrnagAdAI
d1sgja-                                                               
d1u5ha-                                                               
d2g50a2                                                               
d2p10a1  ( 135 )    ----------------glfrqnleet---gsYaqEve-IaeAhkldLLTT
                                                                      

                             860       870       880       890       900 
d1dqua-  ( 393 )    WMeSklPdykqAkeFAdgVhavwpeqKLAynLSpsfnwkkamprdeqetY
d1dxea-                                                               
d1f61a-  ( 283 )    WMetgtPdleaArqFSeaVkaeypdqmLAYnCspsfnwkkhlddatiakF
d1izca-                                                               
d1jqna-  ( 756 )    ----dWpFFstrLgMLeMVFaKAdlw-----LAeYYDqrLVdkalwplGk
d1kbla1                                                               
d1m3ua-  ( 179 )    VLeCVp--veLAkrIteaL-----aiPVIGiGAGn---------------
d1muma-  ( 186 )    FPe-aItelamYrqFadaV-----qvpILAnItefgaTp--------lft
d1s2wa-  ( 188 )    LMHSkkadpsdIeaFmkaWn---nqgpVVIvPt---kYy--------ktp
d1sgja-                                                               
d1u5ha-                                                               
d2g50a2                                                               
d2p10a1  ( 167 )    PyVfs----pedavaaka------gAdilvchgltgk             
                                                                      

                             910       920       930       940       950 
d1dqua-  ( 443 )    ikrLGalgYAWQFitlaGlhttal--isdtfakayakqg--mrAygelvq
d1dxea-                                                               
d1f61a-  ( 333 )    qkeLAamgFkFQFitlagfhalny--smfdlaygyaqnq--msayve-lq
d1izca-                                                               
d1jqna-  ( 797 )    eLrnlQee------DikvVlaIandshlMadlpwiaeSIqlRniyTdPLN
d1kbla1                                                               
d1m3ua-  ( 207 )    -------vTdGQiLvMhdAFgitgghipkfAknFlaetgdiraAVrqYma
d1muma-  ( 222 )    tdeLrsahVaMALyplsaframnr--aaehvynvlrqegt-qksVidtmq
d1s2wa-  ( 224 )    tdhFrdmgVsMVIwanhnlrasvs--aiqqttkqiyddqs-lvnVedkiv
d1sgja-                                                               
d1u5ha-                                                               
d2g50a2                                                               
d2p10a1                                                               
                                                                      

                             960       970       980       990 
d1dqua-  ( 489 )    epeman-----gvdvvthqkwsGanyvdnmlkmitgg      
d1dxea-                                                        
d1f61a-  ( 378 )    erefaa--eergytatkhqrevGagyfdriattvdpnssttal
d1izca-                                                        
d1jqna-  ( 841 )    VLQAELLhrsrqaekegqepdprveqALMVTIagIaaGMrnTg
d1kbla1                                                        
d1m3ua-  ( 250 )    eVesGvYPgeehSfh                            
d1muma-  ( 269 )    t-------------rnelyesinyyqyeekldnlf-------a
d1s2wa-  ( 271 )    s-------------vkeifrl                      
d1sgja-                                                        
d1u5ha-                                                        
d2g50a2                                                        
d2p10a1                                                        
                                                               

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla ç
positive phi: italic x

Jmol view

Jmol Model View
Jmol Command prompt
Response Logs

Tree based on RMSD between structures

Matrices

1. Percentage Identity Matrix  [View | Download]
2. Distance Matrix  [View | Download]

PCA based on sequence identity

1. PCA  [View]
2. Plot file  [Download]

CUSP Results

CUSP Result   [View | Download]

Alistat - Alignment Statistics

Alignment Statistics  [Download]

SMotif - Conserved Structural Motifs

SMotif Result   [View | Download]

MeanRMS

MeanRMS  [Download]