PASS2
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Superfamily Details

Superfamily summary
Superfamily Name:  Metallo-dependent hydrolases
Class Name:  Alpha and beta proteins (a/b)
Fold Name:  TIM beta/alpha-barrel
Number of Members:  41
Average Size: 
Members
SCOP ID Name Source
d1a4ma- Adenosine deaminase (ADA) Mouse (Mus musculus) [TaxId: 10090]
d2amxa1 Adenosine deaminase (ADA) Plasmodium yoelii [TaxId: 5861]
d2a3la1 AMP deaminase (AMPD), catalytic domain Thale cress (Arabidopsis thaliana) [TaxId: 3702]
d2eg6a1 Dihydroorotase Escherichia coli [TaxId: 562]
d1ra0a2 Cytosine deaminase catalytic domain Escherichia coli [TaxId: 562]
d4ubpc2 alpha-subunit of urease, catalytic domain Bacillus pasteurii [TaxId: 1474]
d1gkpa2 D-hydantoinase Thermus sp. [TaxId: 275]
d1nfga2 D-hydantoinase Burkholderia pickettii [TaxId: 329]
d1gkra2 L-hydantoinase Arthrobacter aurescens [TaxId: 43663]
d1xrta2 Two-domain dihydroorotase Aquifex aeolicus [TaxId: 63363]
d2fvka2 Dihydropyrimidine amidohydrolase Pyd2 Yeast (Saccharomyces kluyveri) [TaxId: 4934]
d2ftwa2 Dihydropyrimidine amidohydrolase Pyd2 Dictyostelium discoideum [TaxId: 44689]
d1p1ma2 Hypothetical protein TM0936, probable catalytic domain Thermotoga maritima [TaxId: 2336]
d2paja2 Hypothetical protein GOS 1943094 Environmental samples
d2i9ua2 Guanine deaminase Clostridium acetobutylicum [TaxId: 1488]
d2ooda2 Guanine deaminase Bradyrhizobium japonicum [TaxId: 375]
d1onwa2 Isoaspartyl dipeptidase, catalytic domain Escherichia coli [TaxId: 562]
d1un7a2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain Bacillus subtilis [TaxId: 1423]
d1o12a2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain Thermotoga maritima [TaxId: 2336]
d1yrra2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain Escherichia coli [TaxId: 562]
d1m7ja3 N-acyl-D-aminoacid amidohydrolase, catalytic domain Alcaligenes faecalis [TaxId: 511]
d1j6oa- Hypothetical protein TM0667 Thermotoga maritima [TaxId: 2336]
d1yixa1 Putative deoxyribonuclease YcfH Escherichia coli [TaxId: 562]
d1xwya1 Deoxyribonuclease TatD (MttC) Escherichia coli [TaxId: 562]
d1zzma1 Putative deoxyribonuclease YjjV Escherichia coli [TaxId: 562]
d1i0da- Phosphotriesterase (parathion hydrolase, PTE) Pseudomonas diminuta [TaxId: 293]
d1bf6a- Phosphotriesterase homology protein Escherichia coli [TaxId: 562]
d1itua- Renal dipeptidase Human (Homo sapiens) [TaxId: 9606]
d1j5sa- Uronate isomerase TM0064 Thermotoga maritima [TaxId: 2336]
d2qeec1 Uncharacterized protein BH0493 Bacillus halodurans [TaxId: 86665]
d2icsa2 Putative adenine deaminase EF0837 Enterococcus faecalis [TaxId: 1351]
d2ffia1 Putative 2-pyrone-4,6-dicarboxylic acid hydrolase PP1699 Pseudomonas putida [TaxId: 303]
d2dvta1 Thermophilic reversible gamma-resorcylate decarboxylase Rhizobium sp. MTP-10005 [TaxId: 267998]
d2hbva1 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase NbaD Pseudomonas fluorescens [TaxId: 294]
d2gwga1 4-oxalomesaconate hydratase LigJ Rhodopseudomonas palustris [TaxId: 1076]
d2f6ka1 Putative amidohydrolase LP2961 Lactobacillus plantarum [TaxId: 1590]
d2imra2 Hypothetical protein DR0824 Deinococcus radiodurans [TaxId: 1299]
d2p9ba2 Uncharacterized protein BL1453 Bifidobacterium longum [TaxId: 216816]
d2puza2 Imidazolonepropionase Agrobacterium tumefaciens [TaxId: 358]
d2qs8a2 Xaa-Pro dipeptidase Alteromonas macleodii [TaxId: 28108]
d2r8ca2 Uncharacterized protein EAJ56179 Unidentified organism [TaxId: 32644]

Alignment Based On Similarities In Structural Features using Comparer

                             10        20        30        40        50  
d1a4ma-  (   4 )                                                      
d1bf6a-  (   2 )                                                      
d1gkpa2  (  55 )                                                      
d1gkra2  (  55 )                                                      
d1i0da-  (  35 )                                                      
d1itua-  (   1 )                                                      
d1j5sa-  (   0 )                                                     h
d1j6oa-  (  -4 )                                                      
d1m7ja3  (  62 )                                                      
d1nfga2  (  52 )                                                      
d1o12a2  (  44 )                                                      
d1onwa2  (  63 )                                                      
d1p1ma2  (  50 )                                                      
d1ra0a2  (  56 )                                                      
d1un7a2  (  58 )                                                      
d1xrta2  (  56 )                                                      
d1xwya1  (   1 )                                                      
d1yixa1  (   1 )                                                      
d1yrra2  (  54 )                                                      
d1zzma1  (   1 )                                                      
d2a3la1  ( 212 )    qpdpiaadilrKepeqetfvRlnvplevptsdeveAykcLqeCLelrkry
d2amxa1  (  20 )                                                      
d2dvta1  (   1 )                                                      
d2eg6a1  (   4 )                                                      
d2f6ka1  (   2 )                                                      
d2ffia1  (  10 )                                                      
d2ftwa2  (  60 )                                                      
d2fvka2  (  57 )                                                      
d2gwga1  (   2 )                                                      
d2hbva1  (   3 )                                                      
d2i9ua2  (  67 )                                                      
d2icsa2  (  55 )                                                      
d2imra2  (  91 )                                                      
d2ooda2  (  73 )                                                      
d2p9ba2  (  71 )                                                      
d2paja2  (  70 )                                                      
d2puza2  (  80 )                                                      
d2qeec1  (   2 )                                                      
d2qs8a2  (  64 )                                                      
d2r8ca2  (  58 )                                                      
d4ubpc2  ( 132 )                                                      
                                                                      

                             60        70        80        90        100 
d1a4ma-  (   4 )                                                      
d1bf6a-  (   2 )                                                      
d1gkpa2  (  55 )                                                      
d1gkra2  (  55 )                                                      
d1i0da-  (  35 )                                                      
d1itua-  (   1 )                                                      
d1j5sa-  (   1 )    mfLgedylLtn--raAvrLfneVkdlpIVDPHNhldAkdIvenkpwnDIW
d1j6oa-  (  -4 )                                                      
d1m7ja3  (  62 )                                                      
d1nfga2  (  52 )                                                      
d1o12a2  (  44 )                                                      
d1onwa2  (  63 )                                                      
d1p1ma2  (  50 )                                                      
d1ra0a2  (  56 )                                                      
d1un7a2  (  58 )                                                      
d1xrta2  (  56 )                                                      
d1xwya1  (   1 )                                                      
d1yixa1  (   1 )                                                      
d1yrra2  (  54 )                                                      
d1zzma1  (   1 )                                                      
d2a3la1  ( 262 )    vfqetvapwekeepfahypqgksdhcfeMqdGvVhVfankdakedlfpva
d2amxa1  (  20 )                                                      
d2dvta1  (   1 )                                                      
d2eg6a1  (   4 )                                                      
d2f6ka1  (   2 )                                                      
d2ffia1  (  10 )                                                      
d2ftwa2  (  60 )                                                      
d2fvka2  (  57 )                                                      
d2gwga1  (   2 )                                                      
d2hbva1  (   3 )                                                      
d2i9ua2  (  67 )                                                      
d2icsa2  (  55 )                                                      
d2imra2  (  91 )                                                      
d2ooda2  (  73 )                                                      
d2p9ba2  (  71 )                                                      
d2paja2  (  70 )                                                      
d2puza2  (  80 )                                                      
d2qeec1  (   2 )           sInsrevLaekVknAVnnqpVTDMHThLfSPnFgeiLlw-dId
d2qs8a2  (  64 )                                                      
d2r8ca2  (  58 )                                                      
d4ubpc2  ( 132 )                                                      
                                                                      

                             110       120       130       140       150 
d1a4ma-  (   4 )                                                      
d1bf6a-  (   2 )                                                      
d1gkpa2  (  55 )                                                      
d1gkra2  (  55 )                                                      
d1i0da-  (  35 )                                                      
d1itua-  (   1 )                                                    df
d1j5sa-  (  49 )    eVEGatdhyVwelMrrc-gvseeyItgsrsnkekWlaLAkV-FprFv-gn
d1j6oa-  (  -4 )                                                      
d1m7ja3  (  62 )                                                      
d1nfga2  (  52 )                                                      
d1o12a2  (  44 )                                                      
d1onwa2  (  63 )                                                      
d1p1ma2  (  50 )                                                      
d1ra0a2  (  56 )                                                      
d1un7a2  (  58 )                                                      
d1xrta2  (  56 )                                                      
d1xwya1  (   1 )                                                      
d1yixa1  (   1 )                                                      
d1yrra2  (  54 )                                                      
d1zzma1  (   1 )                                                      
d2a3la1  ( 324 )    dataFFtdLhhVlkVIaagnIrtlChrRLvlLeqkFnlHlmlNadkEflA
d2amxa1  (  20 )                               eikfLkkedvqnidlngmskker
d2dvta1  (   1 )                                                      
d2eg6a1  (   4 )                                                      
d2f6ka1  (   2 )                                                      
d2ffia1  (  10 )                                                      
d2ftwa2  (  60 )                                                      
d2fvka2  (  57 )                                                      
d2gwga1  (   2 )                                                      
d2hbva1  (   3 )                                                      
d2i9ua2  (  67 )                                                      
d2icsa2  (  55 )                                                      
d2imra2  (  91 )                                                      
d2ooda2  (  73 )                                                      
d2p9ba2  (  71 )                                                      
d2paja2  (  70 )                                                      
d2puza2  (  80 )                                                      
d2qeec1  (  44 )    eLL--TYhyLVaeVmrwTdvsieaFw-amskreqAdlIweeLFikrspvs
d2qs8a2  (  64 )                                                      
d2r8ca2  (  58 )                                                      
d4ubpc2  ( 132 )                                                      
                                                                      

                             160       170       180       190       200 
d1a4ma-  (   4 )          tpAFnkpKVELHVhLDGAIkpeTIlyFGkkrgiaLpad------
d1bf6a-  (   2 )                                                      
d1gkpa2  (  55 )                                                      
d1gkra2  (  55 )                                                      
d1i0da-  (  35 )                                                      
d1itua-  (   3 )    frdeAerIMrdspVIDGHNd------LPwqLldm-------------Fnn
d1j5sa-  (  96 )    pTyeWIHLDLwrrFnIk-------kvIseetAeeIWeeTkkkLp------
d1j6oa-  (  -4 )                                                      
d1m7ja3  (  62 )                                                      
d1nfga2  (  52 )                                                      
d1o12a2  (  44 )                gfVDPHIh----gvv------g-------------adt
d1onwa2  (  63 )                gfIDQhVh----LiGgGGea------------------
d1p1ma2  (  50 )                alFNTHThAPMT----lLrgvAe---------------
d1ra0a2  (  56 )                pfVEPHIHLDTTqTAGqpnwnq----------------
d1un7a2  (  58 )                gmIDIHIH----GGY------g-------------ADT
d1xrta2  (  56 )                                                      
d1xwya1  (   1 )                                                      
d1yixa1  (   1 )                                                      
d1yrra2  (  54 )                gfIDVQLN----GCg------g-------------vqF
d1zzma1  (   1 )                                                      
d2a3la1  ( 374 )    qkSAphrdfynVrKVdTHVHHsaCMnqkhLlrfIksklrkepdevVifrd
d2amxa1  (  43 )    y-----eIWrrIPKVELHChLDlTFsaeFFlkWArkyn-lqpnm------
d2dvta1  (   1 )             mq-gKVALEEH----F--AIpeTlqdsagfvp---------
d2eg6a1  (   4 )                                              sqvlk---
d2f6ka1  (   2 )                skIDFHTH----Y--LPtsYveALkrhvp---------
d2ffia1  (  10 )             lhltaIDSHAh----V--FsrglNlasqrr-----------
d2ftwa2  (  60 )                                                      
d2fvka2  (  57 )                                                      
d2gwga1  (   2 )                 iIdIhgH----YttApkaLedWrnrqiagikdpsvpk
d2hbva1  (   3 )              k-prIDMHSH----F--FPrIseqeAakfdanhAPwLqvs
d2i9ua2  (  67 )               pgMNDLHAHASQy----knlgigm---------------
d2icsa2  (  55 )                gwIDDhVH----Cfeka---------------------
d2imra2  (  91 )               pppvNAHTHLDMs----ayEFqAL---------------
d2ooda2  (  73 )               pgfIDGHIHLPQt----rvlg-ay---------------
d2p9ba2  (  71 )               pglINAHThLfsy--------------------------
d2paja2  (  70 )               pawVNTHHHLFqS----llkg------------------
d2puza2  (  80 )               palIDCHTHLVFGgnramEfemrln--------------
d2qeec1  (  91 )    eACrGVltCLqgL-gld----------patr---dlqvYReyFa------
d2qs8a2  (  64 )                gl--DHVhFGq-eyqskaqapi----------------
d2r8ca2  (  58 )                glIDLHVHVVAIeFnlprVat-----------------
d4ubpc2  ( 132 )                                                      
                                                                      

                             210       220       230       240       250 
d1a4ma-  (  42 )    ----tveeLrniIGmdk---------------------p-lsLpgFlakf
d1bf6a-  (   2 )                           sfdpt--gyTLAHEHLhIdlsgfk---
d1gkpa2  (  55 )                    fIDPHVHIyl-----pf-----------------
d1gkra2  (  55 )                   gvVDEHVhIiD------------------------
d1i0da-  (  35 )                   drInTVrgpitiseAgfTLTHEhIcgSsagfLra-
d1itua-  (  34 )    r---------Lqd-------------------------------------
d1j5sa-  ( 133 )    --------------------------------------------------
d1j6oa-  (  -4 )                               h-hhhVDTHAHL---HfhqFd--
d1m7ja3  (  62 )                   gfIDSHTHDDN------------------------
d1nfga2  (  52 )                   gGIDVHThVet-----vs-----------------
d1o12a2  (  60 )    ----------n---------------------------------------
d1onwa2  (  79 )    --------------------------------------------------
d1p1ma2  (  69 )    ---------------------------------------dlsfeewlfs-
d1ra0a2  (  78 )    ----------------------------sgt----------------lfe
d1un7a2  (  73 )    M---------d---------------------------------------
d1xrta2  (  56 )                   gfIDIHVHLRD-----p------------------
d1xwya1  (   1 )                                   mFDIGVnL---tssqFa--
d1yixa1  (   1 )                                 mfLVDSHChL---dgLdye--
d1yrra2  (  69 )    N---------dta-------------------------------------
d1zzma1  (   1 )                               micrfIDTHChF---DfppFs--
d2a3la1  ( 424 )    gtyltLreVFesLdltgydlnvdlldvHadk------stfhrfdkfnlky
d2amxa1  (  81 )    ----sddeIldhYLFtk---------------------egkslaefirka
d2dvta1  (  26 )    --------------------------------g-----------------
d2eg6a1  (   9 )    -------------IrrPDDWHLhLrd-----g------------------
d2f6ka1  (  25 )    --------------------------------g-----------------
d2ffia1  (  34 )    -----------------------yaP-----n------------------
d2ftwa2  (  60 )                  pgGIDTHThFql-----pf-----------------
d2fvka2  (  57 )                   gGIDAHVhVde-----pl-----------------
d2gwga1  (  36 )    v---------selkIs----------------------------------
d2hbva1  (  36 )    a---------kgdtgsImmgknnfrp-----vy-----------------
d2i9ua2  (  87 )    ---------------------------------------dkeLlpWlnn-
d2icsa2  (  69 )    --------------------------------------------------
d2imra2  ( 111 )    ------------------------------------------PYfqwip-
d2ooda2  (  92 )    ---------------------------------------geqLlpWlqk-
d2p9ba2  ( 114 )    --------------------------------------------------
d2paja2  (  87 )    --------------------------------------------------
d2puza2  ( 105 )    -----------------------gatyeeIa------k---------agG
d2qeec1  ( 121 )    --------------------------------------------------
d2qs8a2  (  85 )    --------------------------------------------------
d2r8ca2  (  79 )    --------------------------------------------------
d4ubpc2  ( 132 )                   gGIDTHVHfin------------------------
                                                                      

                             260       270       280       290       300 
d1a4ma-  (  66 )    d-----yYMpVIAG-c-----reAIkrIAyeFVemKakegVvYVEVRYSP
d1bf6a-  (  24 )    -------------n-nvdcrLd--qyafIcqEMndLmtrgVrNVIEMTN-
d1gkpa2  (  67 )    ----------m-atf---------AkdtHetGSkaAlmGgTtTYIEM---
d1gkra2  (  66 )    ----------mdlkn---------rygrFeldSesAavGgItTIIEM---
d1i0da-  (  69 )    -------------w-peffgsrkaLaekAvrgLrrAraagVrTIVDVST-
d1itua-  (  38 )    ---------------erAn---LttLagThTnipkLraGfVgGQFWS---
d1j5sa-  ( 133 )    ------------------------emtPqkLLrdM----kVeiLcTt---
d1j6oa-  (  14 )    --------------------------ddrnavissFeennIeFVVNVGv-
d1m7ja3  (  73 )    ----------yLlkh---------r------dMtPKisQgVtTVVTG--N
d1nfga2  (  65 )    ----------f-ntq---------SadtFatATvaAacGgTtTIVDf---
d1o12a2  (  61 )    -----------------C------dF---se-eefLysqgVtTfLAT---
d1onwa2  (  79 )    ----------------gpt---trTpeV---alsrLteagVtSVVGl---
d1p1ma2  (  79 )    ---kVlpiedrL-t-------ekmAyyGTilAQmeMarhgIaGFVDMyf-
d1ra0a2  (  84 )    GIerWaerkalLt--------hddVkqrAwqTLkwQiangIqHVRTHVD-
d1un7a2  (  75 )    -----------------As---fsTL---diMSsrLpeEgTtSFLAT---
d1xrta2  (  68 )    ------------gqt---------ykedIesGSrcAvaggFtTIVCM---
d1xwya1  (  15 )    --------------------------kdrddVVacAfdagVnGLLITGt-
d1yixa1  (  17 )    -----------------------slHkdVddVLakAaardVkFCLAVAt-
d1yrra2  (  73 )    ---------------eaVs---veTL---eiMQkaneksgCtNYLPT---
d1zzma1  (  19 )    --------------------------gdeeaSlqrAaqagVgkIIVPAT-
d2a3la1  ( 468 )    npcgqSrlreIFlk-qdnliqGrFLGeITkqvFsdleaskyqMAEYRIsI
d2amxa1  ( 106 )    i-----sVSdL-Yr-d-----ydFIedLAkwAVieKykeGVVLMEFRYsP
d2dvta1  (  27 )    ----------dyw--kelq---hrLldIqdtRlklMdahgIetMILS---
d2eg6a1  (  23 )    --------------------------dmLktVVpyTSe-iYgrAIVM---
d2f6ka1  (  26 )    ----------dpd--gwpt---p--ewtpqlTlnF-rdndIsysILs---
d2ffia1  (  38 )    ------------------------ydAplgdYlgqLrahgFshGVLV---
d2ftwa2  (  74 )    ----------m-gtv---------SvddFdiGTqaAvaggTtFIIDf---
d2fvka2  (  70 )    ----------kllgd---------VvdtMehATrsAvaggTtTVVAf---
d2gwga1  (  43 )    ------------d--deLq---asIi---enqlkk-qergsdltVFS---
d2hbva1  (  55 )    ----------------------qALWd-pafRieeMdaqgVdvQVTC---
d2i9ua2  (  97 )    ---yTfpeEakFln-------vdyAkkTYgrLikdLikngTtrVALFATl
d2icsa2  (  69 )    -----------------------lyyDy---pdeIGvkkgVtTVIDa---
d2imra2  ( 118 )    ---eVvirGrhlrg-----------vaaAqagAdtLtrlgaggVGDIVwa
d2ooda2  ( 102 )    ---sIYpEEikYkd-------rnyAregVkrFldaLlaagTtTCQAFTSs
d2p9ba2  ( 114 )    -------------------------aatvkhnAttLlesgVtTIRTLGDv
d2paja2  (  87 )    -----epfralf-d-------errFrlAAriGLieLarSgCaTVADHNyV
d2puza2  ( 117 )    givsSvrdTrals--------devLVaqAlprLdtLlsegVsTIEIKSGY
d2qeec1  ( 121 )    ------------------------kktseeQVdtVLqlAnVsdVVMt---
d2qs8a2  (  85 )    ----------kve--------r-eqailAtqhAyvTfksgFttVRQVgds
d2r8ca2  (  79 )    -----------lp--------nvlVtlrAvpiMraMlrrgFtTVRDAGGA
d4ubpc2  ( 143 )    -----------------------------pdQVdvAlangItTLFGG---
                                                aaaaaaaaa   bbbbbb    

                             310       320       330       340       350 
d1a4ma-  ( 105 )    HlL--AnskVdpmpwnqtegdVtPd----dVVdlVNqGLqeGeqafg---
d1bf6a-  (  57 )    ---------------------ryMg----RnAqfMldVmreT--------
d1gkpa2  (  94 )    ---CCPsrnd----dal------------egYqlWkskAeg---------
d1gkra2  (  94 )    ---PiTf----ppTttl------------daFleKkkqAgq---------
d1i0da-  ( 104 )    ---------------------fDIG----RdVsLLaeVSraA--------
d1itua-  (  67 )    ---VyTp--çdtqnk---dAvrrTl----eQMdVVhrMCrmypeTFlyvt
d1j5sa-  ( 152 )    ---ddPvs-----------------------tLehhrkAke---------
d1j6oa-  (  37 )    ---------------------nLed------SkkSldlSkts--------
d1m7ja3  (  96 )    CGISLAPLahanPpaPLdLLdeggSFrF-arFsdYlealra---------
d1nfga2  (  92 )    ---CqQdrgh----sLa------------eAvakWdgmAgg---------
d1o12a2  (  82 )    ---tvSt--s----------lek-k----eilrkArdyilenp-------
d1onwa2  ( 104 )    ---Lgtd--Si-------------s----rhpesLlakTraLneeg----
d1p1ma2  ( 117 )    ------------------------------hEewIAkAVrdf--------
d1ra0a2  ( 125 )    VSd-----------------at--L----tALkAMleVkqeVa----p--
d1un7a2  (  99 )    ---TITq--e----------hgnIs----qALvnAreWkaaee-------
d1xrta2  (  94 )    ---PNtn----ppIdnt------------tVVnyIlqksks---------
d1xwya1  (  38 )    ---------------------nlre------SqqAQklArqy--------
d1yixa1  (  43 )    ---------------------tlps------YlhMrdlVger--------
d1yrra2  (  99 )    ---Litt--s----------delMk----qGVrVMreYlakhp-------
d1zzma1  (  42 )    ---------------------eAen------farVlalAeny--------
d2a3la1  ( 517 )    yGr--k------------------m----seWdqLAsWIvnn--dLyS--
d2amxa1  ( 144 )    tfV--sssy-----------gldve----lIHkAFikgiknAtellnn--
d2dvta1  (  59 )    ---LNap--AVQaipdrrkAieIAr----rANdvLaeecakrpd------
d2eg6a1  (  43 )    ---Pnla----------------pPVttVeaAvaYrqrIld---------
d2f6ka1  (  56 )    ---LSSp--hVnf-gdkaeTirLVe----aAnddGkslaqqypd------
d2ffia1  (  61 )    ---qPsf--Lg------------------tdnryLlsALqtvpg------
d2ftwa2  ( 101 )    ---ViPtrgq----sLl------------eAydqWkkwAde---------
d2fvka2  (  98 )    ---STqdvskkgpsALA------------eSVklDvdeYse---------
d2gwga1  (  70 )    ---pra--------gdfnvsstwaa----icNeLCyrVsqlfpd------
d2hbva1  (  79 )    ---ATpv--MFgYtweankAaqWAe----rMNdfAlefaahnpq------
d2i9ua2  ( 137 )    h-----------------------k----dSTieLFnmLiks--------
d2icsa2  (  90 )    ----gtT--Ga-------------e-----nIheFydlAqqa---k----
d2imra2  ( 154 )    ------------------------p----eVMdaLLare-----------
d2ooda2  ( 142 )    s-----------------------p----vATeELFeeasrr--------
d2p9ba2  ( 139 )    g-----------------------y----eVvtLrdqidagqi----l--
d2paja2  ( 141 )    Yyp------------------gmpf----dSSaILFeEAekl--------
d2puza2  ( 159 )    GLd-----------------ietEL----kMLrVArrLetlr--------
d2qeec1  ( 144 )    ---NdPFd-----------------------d-nerisWle---------
d2qs8a2  ( 117 )    g-----------------------l----vAIslrdainsgkl----a--
d2r8ca2  ( 110 )    g------------------------------ypfkqaVesglv----e--
d4ubpc2  ( 161 )    ---Gtgpa---------egSkaTtVTpgpwnIekmLksTeg---------
                                                   aaaaaaaaa          

                             360       370       380       390       400 
d1a4ma-  ( 146 )    -------------ikVrSILCCmR-------------h-----------q
d1bf6a-  (  74 )    ------------gInVvACTGYy--qdafFpehVat--------------
d1gkpa2  ( 116 )    ------n----SycdytFHMA----VSkfd--------------------
d1gkra2  ( 116 )    ------r----LkvdfaLYGG----Gvp----------------------
d1i0da-  ( 121 )    ------------dVhIVAATGLw--f--dpplsmrl--------------
d1itua-  ( 105 )    sSagIrqAfregkVASLIGVE----GGHSId-------------------
d1j5sa-  ( 167 )    ------aVe---gVtIlPTWr----PdrAMnVdkegWreYVekMGeryge
d1j6oa-  (  52 )    ------------d-rIfCSVGVh--P-hdAkevp----------------
d1m7ja3  ( 136 )    ------a---ppaVnaaCMVG----HSTLRAavMpdlr------------
d1nfga2  ( 114 )    ------k----SaidygYHII----Vldpt--------------------
d1o12a2  ( 106 )    -----------sTSLlGVHlE----GpYIskekkgaHSek----------
d1onwa2  ( 128 )    -------------isAwMLTG----AyhV--pSrTitg------------
d1p1ma2  ( 129 )    ------------gMrALLTrgLvDs------------------ng-----
d1ra0a2  ( 146 )    ------------wIdLqIVAF-PQeGIlSyp-------------------
d1un7a2  ( 123 )    -------sSllgAeLLGIHLE----GPFVSpkrAgaQPke----------
d1xrta2  ( 116 )    ------v----glCrVlPTGT----ITkgrkgk-----------------
d1xwya1  (  53 )    ------------s-sCwSTAGVh--P-hdSsqWq----------------
d1yixa1  (  58 )    ------------d-nVVFSCGVh--P-lnQndpy----------------
d1yrra2  ( 123 )    ------------nqALGLHLE----GpWLNlvkkthn-pn----------
d1zzma1  (  57 )    ------------q-pLyAALGLh--P-gmlekHs----------------
d2a3la1  ( 539 )    ------------e-nVvWLIQLPrL------------YniYkdmgiVtsF
d2amxa1  ( 175 )    ------------kIhVaLICiSdtg------------h-----------a
d2dvta1  (  94 )    --------------rFlAFAa----LPLQ---------------------
d2eg6a1  (  65 )    ------avpaghdFtPlMTCy----LTdsL--------------------
d2f6ka1  (  90 )    --------------qLGYLAS----LPIp---------------------
d2ffia1  (  82 )    --------------qLrGVVl----e------------------------
d2ftwa2  ( 123 )    ------k----vncdysLHVa----ITwws--------------------
d2fvka2  ( 124 )    ------q---tlycdygLHLI----LfqIekps-----------------
d2gwga1  ( 106 )    --------------nFiGAAL----PqSp----------g----------
d2hbva1  ( 114 )    --------------rIkVLAQ----VPLq---------------------
d2i9ua2  ( 152 )    ------------giGAyVGKVNMDy------------------nCpdyLt
d2icsa2  ( 109 )    -------------TnVfGlVN----ISkw--GIvaqdELa----------
d2imra2  ( 165 )    ------------dLsGTLYfEvlnP------------f-------pdkAd
d2ooda2  ( 157 )    ------------n-rVIAGLTgIdr------------------nApaeFi
d2p9ba2  ( 156 )    ------------GPrILASGpl-aipegh---------------------
d2paja2  ( 161 )    ------------glrFVLLRGgaTq------------trqleadLptalr
d2puza2  ( 180 )    ------------pVrIvTSYLAAhaTpadyk-------------------
d2qeec1  ( 158 )    ------gkqpd-s-rFhAALr----LdpLLn----eYeqTkhrLrdwgyk
d2qs8a2  ( 134 )    ------------GPrIfAAGktIAttgGhaDptngkavddyd--------
d2r8ca2  ( 124 )    ------------GPrLfVSgrALSqtgghaDprars---dymppdspcgc
d4ubpc2  ( 190 )    ------lp-----INVGILGk----GHgs---------------------
                                   bbbb                               

                             410       420       430       440       450 
d1a4ma-  ( 159 )    ------------pswSleVLeLCkkYn------------qkTVVAMDLAg
d1bf6a-  (  96 )    -------------rsvqeLaqeMvdeIeqgId-----gtelkAgIIAEIG
d1gkpa2  ( 132 )    ----------------ektegqLreIvad------------gIsSFIF-l
d1gkra2  ( 130 )    -----------------gnlpeIrkMhda------------gAvGFSm-M
d1i0da-  ( 141 )    -------------rsveeLtqfFlrEIqyGIe-----dtgirAgIIK-VA
d1itua-  ( 132 )    -----------------SsLgvLraLyq------------lGMrYLTL-T
d1j5sa-  ( 204 )    dTstL-------dgFlnALwkSHehFke-h-----------gCvaSDHal
d1j6oa-  (  70 )    ----------------edFiehLekfAk--d---------ekVvAIGETG
d1m7ja3  ( 161 )    --reAt------adeiqaMqalAddALas------------gAiGIST-G
d1nfga2  ( 130 )    ----------------dsVieeLevLpdl------------gItsFVf-M
d1o12a2  ( 131 )    -------------hIrpPsereLseid-------------sPAk-LTF-A
d1onwa2  ( 147 )    ---------------------svekDVaii----------drVIGVCA-I
d1p1ma2  ( 144 )    --------------ddggrLeeNlkLynewngfeg-----rIfVGFGPhS
d1ra0a2  ( 164 )    -----------------nGealLeeALrl-----------g-AdVVGAI-
d1un7a2  ( 152 )    -------------wIrpSdvelFkkWqqeA---------gglIkIVTL-A
d1xrta2  ( 135 )    ------------------eiAdFysLkea------------gCvAFTD-D
d1xwya1  (  71 )    ----------------aateeaIielAa--q---------peVvAIGeCG
d1yixa1  (  76 )    ----------------d--vedLrrLAa--e---------egVvALGETG
d1yrra2  ( 147 )    -------------fvrkpdaalVdfLcena----------dVItKVTL-A
d1zzma1  (  75 )    ----------------dvSleqLqqaLerrp---------akVvAVGEIG
d2a3la1  ( 564 )    ------------qnILdNIFiPLFeATvdPdshpqLhVFLkqVvGFDLVD
d2amxa1  ( 190 )    ------------aasikhSGdfAikhk------------h-dFvGFDHgg
d2dvta1  ( 105 )    --------------dpdaAteeLqrCvndl-----------gFvGALV-N
d2eg6a1  (  85 )    ------------------dpneLerGfneg-----------VFtAALy--
d2f6ka1  ( 101 )    --------------yeldAvktVqqAldqd-----------gAlGVTV-P
d2ffia1  (  91 )    ---------------rdveqatLaea--rl-----------gVrGVRl-n
d2ftwa2  ( 139 )    ----------------eqVsreMeiLvker-----------gVnSFCf-M
d2fvka2  ( 144 )    ------------vearelldvqLqaAyndy-----------gVssVMf-M
d2gwga1  ( 119 )    -------------vdpktCipeLekCVkeY-----------gFVaInL-n
d2hbva1  ( 125 )    --------------dldlAckeAsrAva-a-----------gHlGIQI-G
d2i9ua2  ( 172 )    -------------enyitSlndteeIIlkYkdksn-----iVkPIITPRF
d2icsa2  ( 130 )    -------------dlskVqaslVkkAiqel---------pdFVvGIAr-s
d2imra2  ( 184 )    ------------e-vfaaarthLerWrrlerp--------gLrLGLSPHT
d2ooda2  ( 177 )    -------------dtpenFyrdSkrLIaqyhdk-g-----rnlYAITPRF
d2p9ba2  ( 173 )    ----gaplialtsgtpeeArtaVaqNlka-----------g-VnAIKiaa
d2paja2  ( 187 )    ------------petldaYvadIerLAarYhdasprA---mrrVVMAPtt
d2puza2  ( 199 )    ----grn----adYItdvVlpGLekAhae-----------glAdAVDGfC
d2qeec1  ( 192 )    Vndewn------egSiqeVkrFLtdWierM-----------dPVYMaVsL
d2qs8a2  ( 164 )    ypvpeq--GVVn--gpyeVyaAVrqRykd-----------g-AdgIKITV
d2r8ca2  ( 159 )    cvrvGalGrVAd--gvdeVrrAVreELqm-----------g-AdQIKImA
d4ubpc2  ( 204 )    ------------------siapImeQIda------------GAAGLIh--
                                       aaaaaaaaa                bbbb  

                             460       470       480       490       500 
d1a4ma-  ( 185 )    ---------dEtie------------------gSSlfpgHve-AYegAvk
d1bf6a-  ( 128 )    -------Tseg-------------------kitplEekVFiA-AAlAhnq
d1gkpa2  ( 154 )    Sy----k----------------------nff-GVddgeMyq-TLrLAke
d1gkra2  ( 151 )    Aa--svp----------------------gmFdaVsdgeLfe-IFqeIaa
d1i0da-  ( 172 )    -------Tt-g-------------------kAtpfqelVLkA-AArASla
d1itua-  ( 152 )    hsçnTpWADNwlvdtgdsepqsqGLs-----------pFGqr-VVkELNR
d1j5sa-  ( 235 )    l-ePsVyyVdenrAraVHekAfsgekLtqdeindYkAfMMvq-FGkmNqe
d1j6oa-  (  93 )    -------LDff----------------rniSpaevQkrVFve-QIeLAgk
d1m7ja3  ( 190 )    Af--Y------------------------pPAahAsteEIIe-VCrPLit
d1nfga2  ( 152 )    Ay----r----------------------gmN-mIddvTLlk-TLdkAvk
d1o12a2  ( 154 )    Pei-e----------------------------------sSe-lLlrLvk
d1onwa2  ( 166 )    s----D----------hrsaapdv-------------yhLAn-MAaeSrv
d1p1ma2  ( 175 )    ---------P-ylCs---------------------eeYLkr-VFdtAks
d1ra0a2  ( 184 )    ---------PH--fEft---------------reyGveSLhk-TFaLAqk
d1un7a2  ( 179 )    PeeDq----------------------------------hfe-LIrhLkd
d1xrta2  ( 154 )    Gs--pVm----------------------------dssvMrk-ALelAsq
d1xwya1  (  94 )    -------LDfn----------------rnfStpeeQerAFva-QLrIAad
d1yixa1  (  97 )    -------LDyy----------------ytpetkvrQqesFih-HIqIGre
d1yrra2  ( 173 )    PemVP-----------------------------------ae-VIskLan
d1zzma1  ( 100 )    -------Ldlf----------------gddpqferQqwLLde-QLklAkr
d2a3la1  ( 602 )    ---------dEskperrPtkhmptPaqwtnafnPaFSYYVYY-CYANLyV
d2amxa1  ( 215 )    ---------rei-----------------------dlkdHkd-VYhsVrd
d2dvta1  ( 129 )    g----FSqeg------dGqtplyYdl-----------pqYrp-FWgeVek
d2eg6a1  ( 105 )    panattn----------------------sshgVtsvdaImp-VLerMek
d2f6ka1  ( 125 )    T----NSr------------glyFgs-----------pvLer-VYqeLda
d2ffia1  ( 113 )    l----g-------------qdpdLtg-----------aqwrp-LLerIge
d2ftwa2  ( 162 )    Ay----k----------------------nsf-mVtdqeMyh-IFkrCke
d2fvka2  ( 171 )    Ty----p-----------------------gl-qIsdydIms-AMyATrk
d2gwga1  ( 144 )    p----dpsgg------h-wtsppLtd-----------riWyp-IYekv-e
d2hbva1  ( 148 )    N----hlg------------dkdLdd-----------atLea-FLthCAn
d2i9ua2  ( 204 )    ---------V-PsCs---------------------neLMdg-LGklSyk
d2icsa2  ( 159 )    r---------------tVIgdngi-------------tPlel-AkqIQqe
d2imra2  ( 213 )    ---------P-FTVS---------------------hrLMrl-LSdyAag
d2ooda2  ( 208 )    ---------A-fGAs---------------------peLLka-CqrLkhe
d2p9ba2  ( 207 )    ---------tggvtd----aqe----------iq-sveq-rA-iCdeAhq
d2paja2  ( 222 )    ---------VlysIs---------------------preMre-TAavArr
d2puza2  ( 230 )    ---------Eg--iAFs-------------------vkeIdr-VFaaAqq
d2qeec1  ( 225 )    pptFsFpe------------------------esnrGrIIrdCLLpVAek
d2qs8a2  ( 198 )    ---------TGGvlsvaksgqn----------pqFtqeeVda-VvsAAkd
d2r8ca2  ( 195 )    ---------SGGVaSptDpVgv----------fgYsedeIra-IvaeAqg
d4ubpc2  ( 223 )    edw------------------------------gAtpasIdr-SLtVAde
                                                         aaaaa aaaaaaa

                             510       520       530       540       550 
d1a4ma-  ( 207 )    n----------gihrTVhAG--Evg-------------------------
d1bf6a-  ( 151 )    T----------grPISThT---sfS-------------------------
d1gkpa2  ( 176 )    l----------gViVTAHCE--naelVgrlqqklls------egktgpew
d1gkra2  ( 176 )    C----------gSVIVVhAE--netiiqalqkqika------aggkdmaa
d1i0da-  ( 194 )    t----------GvPVTThT---aAsq------------------------
d1itua-  ( 190 )    l----------gVLIDLAhVS-----------------------------
d1j5sa-  ( 283 )    t----------nWVTQLHIGAlrdyr-----dslfk------tlgpdSGg
d1j6oa-  ( 119 )    l----------nlPLVVhIr------------------------------
d1m7ja3  ( 213 )    h----------ggvYATHMr--dEge------------------------
d1nfga2  ( 174 )    t----------gSlVMVHAE--nGdaAdylrdkfva------egktapiy
d1o12a2  ( 168 )    r----------dIvLSAGHSiAt---------------------------
d1onwa2  ( 188 )    GGllggk----pGVTvFhMGdsk---------------------------
d1p1ma2  ( 193 )    l---------n-ApVTIhLY--EtskEe----------------------
d1ra0a2  ( 207 )    y----------drlIDVHCD--Eidde-----------------------
d1un7a2  ( 194 )    e----------sIiASMGHTdAd---------------------------
d1xrta2  ( 173 )    l----------gvPIMDhce--ddklAy----------------------
d1xwya1  ( 120 )    l----------nmPVFMhcr------------------------------
d1yixa1  ( 123 )    l----------nkPVIVhTr------------------------------
d1yrra2  ( 187 )    a----------gIvVSAGhSnAt---------------------------
d1zzma1  ( 126 )    y----------dlPVILhSr------------------------------
d2a3la1  ( 642 )    LNkLReskgmttItLRPhSG--eag-------------------------
d2amxa1  ( 232 )    h----------gLhLTVhAG--eda-------------------------
d2dvta1  ( 157 )    l----------dvPFYLhPRnplpqdsriyd------------ghpwllg
d2eg6a1  ( 132 )    i----------gMPLLVhGe--vtha------------------------
d2f6ka1  ( 147 )    r----------qaiVaLhPnepa--ilpk-n------------vdidlpv
d2ffia1  ( 136 )    q----------gWHVELhr-------------------------------
d2ftwa2  ( 184 )    l----------gAiAQVHAE--nGdmVfegqkkmle------mgitgPeG
d2fvka2  ( 192 )    n----------gFtTMLHAE--nGdmVkwmiealee------qgltdAyy
d2gwga1  ( 171 )    l----------eIPa-IhVst-----------------------------
d2hbva1  ( 170 )    e----------dIpILVHPwdmmgg----qr------------mkkwmlp
d2i9ua2  ( 222 )    y---------r-lpVQShLS--ENldEiavVkslhk--------------
d2icsa2  ( 180 )    Nq----------eipLvhIGsap---------------------------
d2imra2  ( 231 )    e---------g-LpLQIhVA--EhptEleMFrtgggpLWdnrmpalYpht
d2ooda2  ( 226 )    h---------pdCWVNTHIS--eNpaEcsgVlveHp--------------
d2p9ba2  ( 239 )    y----------gvIVGAhAQ--S---------------------------
d2paja2  ( 241 )    l---------g-LrMHShLs--g---------------------------
d2puza2  ( 249 )    r----------glpVKLHAE--qlsn------------------------
d2qeec1  ( 251 )    h----------niPFAMmIGVkkrvh-----palg------------dAG
d2qs8a2  ( 228 )    y----------g-WVAVHaH--g---------------------------
d2r8ca2  ( 225 )    r----------gtyVLAHAY--t---------------------------
d4ubpc2  ( 242 )    a----------dVQVaIhSd--Tl--------------------------
                                  bbbb                                

                             560       570       580       590       600 
d1a4ma-  ( 220 )    -----------spevVreAvdiLkT-------eRVGHGYhTied-----e
d1bf6a-  ( 163 )    ---------tmGleQLalLqahgVd---Lsr-VTVGHCDlk------dNl
d1gkpa2  ( 208 )    HepSR-peaVEaeGTa-rFAt-fLetT--gAtGYVVHLSC---------k
d1gkra2  ( 208 )    YeaSq-pvfQEneAIq-rALl-lQkeA--gCrLIVLHVSN---------P
d1i0da-  ( 207 )    ---------rDGeqQAaiFesegLs---psr-VCIGHSDdt------ddl
d1itua-  ( 201 )    -----------vaTMkaTLq-------lSrApVIFS-HSSAysvÇasr--
d1j5sa-  ( 312 )    D---istnfLr---IaeGLry-FLneFdgkLkIVLYVLd----------p
d1j6oa-  ( 129 )    ---------dAyseAyeiLrtesLP---ekr-GVIHaF-ss-------dy
d1m7ja3  ( 227 )    ---------hIvqALe-eTFr-IGreL--dVpVVISHHKVMgklnfgrSk
d1nfga2  ( 206 )    HAlSR-pprVEAeATa-rALa-lAeiv--nApIYIvHVTC---------e
d1o12a2  ( 181 )    -----------feeF-kFyk---------egVkRIT-hFpngLkplhh--
d1onwa2  ( 207 )    ---------kALqpIydLlenc---dVpisk-LLPT-HVNrnv-------
d1p1ma2  ( 209 )    -------------ydLedIlniGLk-eV--k-TIAAHCVhL--p-----e
d1ra0a2  ( 222 )    -----------qsrfVetVAalAhhegMGar-VTASHTTAMhsYngayts
d1un7a2  ( 207 )    -----------salLsdAak---------AgAsHMT-HLynaMspfhh--
d1xrta2  ( 209 )    ---------aeeiqIa-rDGi-LAqrT--gGhVHIQhVst---------k
d1xwya1  ( 130 )    ---------daherFmtlLepwldk---Lpg-AVlhcF-tg-------tr
d1yixa1  ( 133 )    ---------dAradTlaiLreekVt---dCg-GVLHcF-tE-------dr
d1yrra2  ( 200 )    -----------lkeAkaGFr---------agItFAT-HLynaMpyitg--
d1zzma1  ( 136 )    ---------rTHdkLAmhLkrhd-L---prt-GVVHGF-sg-------sl
d2a3la1  ( 665 )    -----------diDHLAATF--LTC-------hSIAHGInLrkS-----p
d2amxa1  ( 245 )    --------tlpnlntLyTAIniLnV-------eRIGHGIrVSes-----d
d2dvta1  ( 185 )    ptwA--faqeTavHAlrLMasgLFdeh-prLnIILG-hMGEgLPym-Mw-
d2eg6a1  ( 146 )    --dId-ifdrEarFiesvMep-Lrqrl-taLkVVFEHITT---------k
d2f6ka1  ( 172 )    pllg--ff-dTt-TFinL-kyhffeky-pnIkVIIP-hAGAfLgiv-dd-
d2ffia1  ( 145 )    ------qVadIPvlVraLqpyg--------LdIVID-HFGrPdArrglgQ
d2ftwa2  ( 216 )    HelSR-pealEaeATn-rAIv-iAdsv--cTpVYIVHVQS---------i
d2fvka2  ( 224 )    HgvSR-psiVEGeATn-rAit-lAttm--dTpILFVHVSS---------p
d2gwga1  ( 191 )    -gah--ylnaDttAF-qCvagdLFkdf-pelkFvIP-hGGGaVPyh-wg-
d2hbva1  ( 194 )    wlvA--mpaETqlAIlsLIlsGAFerIpksLkICFG-HGGGsFafl-lg-
d2i9ua2  ( 246 )    ----------kSnfYGeVYdkfgLFGnt--p-TLMAHCIhS--s-----k
d2icsa2  ( 194 )    ---------phLdeILale----------kg-dVLt-HCFNgk-------
d2imra2  ( 269 )    LaeVIgrepgpdLtPVrYLdelgVL-aa--r-PtLVHMVnV--t-----p
d2ooda2  ( 251 )    ----------dcqdYlgVYekFdLVg-p--k-FSGGHGVyL--s-----n
d2p9ba2  ( 250 )    ------------pegVrrslla-------GV-DTIEhGSvLd-------d
d2paja2  ( 265 )    ------------kspVafCgehdWLgs---d-VWYAhLvkV--d-----a
d2puza2  ( 263 )    ------------lgGAelAAsy-------nA-lSADHLEyLd-------e
d2qeec1  ( 274 )    D---fvgk-As---m-dGVeh-LLreyp-nNkFLVTMLS----------r
d2qs8a2  ( 239 )    ------------aeG-krAikA-------gV-dSiEhgTf-d-------l
d2r8ca2  ( 236 )    ------------paAIarAVrC-------gV-rTIEHGNlId-------d
d4ubpc2  ( 254 )    ---------neagfle-dTlr-aIn----grvIHSFHVEGA---GGGHap
                                  aaaaaa             bb               

                             610       620       630       640       650 
d1a4ma-  ( 247 )    aLYnrLl--ke-----------------nmHFEVCPwSSy----LTgAwd
d1bf6a-  ( 194 )    dnIlkMI--dl-----------------gAYVQFDTIGkn----------
d1gkpa2  ( 244 )    pAldaAm--aAkar------------gVpIyIESVIPHF-----lldkty
d1gkra2  ( 244 )    dGVelIh--qaqse------------gqdVhCESGpqYL-----nittdd
d1i0da-  ( 238 )    sYLtaLA--ar-----------------gYLIGLDhIPHs----Ai----
d1itua-  ( 230 )    -------------RNVpddVLrlVkq-tdSLVMVNFynnyIsçtn-----
d1j5sa-  ( 345 )    thlptIS--tiAra------------fpnVyVGAPwwfnds---------
d1j6oa-  ( 158 )    ewAkkFi--dl-----------------gFlLGIgGpVTy----p-----
d1m7ja3  ( 264 )    eTLalIe--aama-------------sqdVSLDAYPyvA-GStMLkqdrv
d1nfga2  ( 242 )    eSLeeVm--rAksr------------gVrAlAETCthYL-----yltked
d1o12a2  ( 208 )    -------------re--iGItGAGlllddVkLELICdgvHls--------
d1onwa2  ( 236 )    ---pLFe------------qAleFAr-kgGTIDITSsid-----------
d1p1ma2  ( 235 )    rYFgvLk--di-----------------pFfVSHNPaSNl----kLgng-
d1ra0a2  ( 260 )    rLfrlLk--mS-----------------gINFVANPLVNi----hLQGrf
d1un7a2  ( 234 )    -------------re--pgVigtAlahdgFVTELIAdgiHsh--------
d1xrta2  ( 237 )    lSLeiIe--ffkek------------gVkItCEvnPnhL-----l-----
d1xwya1  ( 159 )    eeMqaCv--ah-----------------gIyIGITGwVCd----er----
d1yixa1  ( 162 )    etAgkLl--dl-----------------gFYISFSGiVTf----r-----
d1yrra2  ( 227 )    -------------re--pgLAgAIldeadIyCGIIAdglhVd--------
d1zzma1  ( 164 )    qqAerFv--ql-----------------gYkIGVGGtIty----pr----
d2a3la1  ( 690 )    VLQYLYY--La-----------------qIGLAMSPlSNn----s-lfld
d2amxa1  ( 275 )    eLIelVk--kk-----------------dILLEVCPiSNl----LLnnvk
d2dvta1  ( 229 )    ridhrnawvklpprypAkrrfmdYFn-eNFhITTSGnfr-----------
d2eg6a1  ( 182 )    dAAdyVr--dgn---------------erLAATITPQHLmfn-----rnh
d2f6ka1  ( 216 )    riaqyAq-----kvy--qvdVydv---hhVyfDVAgaVl-----------
d2ffia1  ( 180 )    pGFaeLltLsGr---------------gkVwVkVSGIyr-Lqgsp-----
d2ftwa2  ( 252 )    gAAdvIc--khrke------------gvrVyGEPIAaGL-----gvdGsh
d2fvka2  ( 260 )    qAaevIk--qAqtk------------glkVyAETCPqYA-----LlSdaI
d2gwga1  ( 234 )    rfrglAqe--------kkplLedhVL-nnIFFDTCv-yh-----------
d2hbva1  ( 239 )    rvdnawrhrdivre-dCprpPseYv--drFfVDSav-fn-----------
d2i9ua2  ( 276 )    eEInlIk--rn-----------------nVtIVHCPTSNf----nLgSg-
d2icsa2  ( 217 )    ---enGIldq--atdkIkdfAwqAyn-kgvvFDIGH-Gt-----------
d2imra2  ( 308 )    dDiarVa--ra-----------------gCaVVTCPRSNh----hLeCg-
d2ooda2  ( 280 )    nEFrrs---kk-----------------gaAvVFCPCSNl----fLgSg-
d2p9ba2  ( 273 )    eLigFrh-npn---Alrg----------ySALIPTlsagL----pltllg
d2paja2  ( 292 )    deialLa--qt-----------------gTGVAhCpqSng----rl----
d2puza2  ( 286 )    tGAkaLa--ka-----------------gTVAVLLPgAfy----alrek-
d2qeec1  ( 304 )    eNQheLV--vlArk------------fsnLmIFGCWwfMnn---------
d2qs8a2  ( 262 )    e-adl-i--en-----------------gtyyVPTIsaGe----fvaekS
d2r8ca2  ( 259 )    eTArlVa--eh-----------------gAYVVPTLVTYd----ALaseG
d4ubpc2  ( 286 )    dIMaMAG--h-----------------pnVLPSSTNPTRPftvn--Tide
                    aaaaaaa                       bbb                 

                             660       670       680       690       700 
d1a4ma-  ( 274 )    pkt-----------------------------------------------
d1bf6a-  ( 215 )    ---------------------------s----y--------------ypd
d1gkpa2  ( 275 )    aer-g----------------------------gveAMkyIMSPPLR-dk
d1gkra2  ( 275 )    ae--------------------------------rigPyMKVaPPVR-sa
d1i0da-  ( 261 )    -gle------------------dnasAsalLgi--------------rsw
d1itua-  ( 261 )    ----------------------------------------------kAnl
d1j5sa-  ( 372 )    -------------------------------------------------p
d1j6oa-  ( 180 )    ------------------------------------------------kn
d1m7ja3  ( 298 )    LLagrTlITwCkpypeLsgrdLeeIAaergkskydVVpeLqpAGAiYfmM
d1nfga2  ( 273 )    Ler-p----------------------------dfeGAkyVFTPPAR-ak
d1o12a2  ( 235 )    --------------------------------------------------
d1onwa2  ( 259 )    ------------------------------------------------ep
d1p1ma2  ( 261 )    --------------------------------------------------
d1ra0a2  ( 287 )    dty---------------------------------------------pk
d1un7a2  ( 261 )    --------------------------------------------------
d1xrta2  ( 285 )    --------------------------------------------------
d1xwya1  ( 182 )    ------------------------------------------------rG
d1yixa1  ( 184 )    ------------------------------------------------nA
d1yrra2  ( 254 )    --------------------------------------------------
d1zzma1  ( 187 )    ------------------------------------------------as
d2a3la1  ( 716 )    yh------------------------------------------------
d2amxa1  ( 302 )    sMd-----------------------------------------------
d2dvta1  ( 267 )    --------------------------------------------------
d2eg6a1  ( 210 )    Mlv--------g------------------gvrphlyClPiLKr-----n
d2f6ka1  ( 246 )    --------------------------------------------------
d2ffia1  ( 209 )    ----------------------------------------------eeNl
d2ftwa2  ( 283 )    Mwnhd----------------------------wrhAAafVMGPPIRpdp
d2fvka2  ( 291 )    Trchgvgi-----dlssiseSPftnpd-----drfIGSkyICSPPIR-pe
d2gwga1  ( 264 )    --------------------------------------------------
d2hbva1  ( 274 )    --------------------------------------------------
d2i9ua2  ( 302 )    --------------------------------------------------
d2icsa2  ( 249 )    ------------------------------------------------ds
d2imra2  ( 334 )    --------------------------------------------------
d2ooda2  ( 306 )    --------------------------------------------------
d2p9ba2  ( 306 )    qdvT------------------gitdiqlenSk--------------nVv
d2paja2  ( 320 )    --------------------------------------------------
d2puza2  ( 312 )    --------------------------------------------------
d2qeec1  ( 331 )    -------------------------------------------------p
d2qs8a2  ( 289 )    kidn------------------fFpeiVrpkAa--------------sVG
d2r8ca2  ( 286 )    e-ky------------------gLppeSiakIa--------------dVh
d4ubpc2  ( 315 )    Hld--------mLmvchhlkq------nip---edvafAdsRIR-----p
                                                                      

                             710       720       730       740       750 
d1a4ma-  ( 277 )    ---tHAVvrFkn----dkANYSLNTDD-P---lIFk--------------
d1bf6a-  ( 220 )    ekRiamLhaLrdrgl-lnr-VMLSMdI-t------------rrshLkan-
d1gkpa2  ( 295 )    rNqkvLwdALaq---gf-I-dTVGTdHCpFd-t---------eqKllG-k
d1gkra2  ( 292 )    emnirLWeQLen---gl-I-DTLGSdHgghp----------vedKepGw-
d1i0da-  ( 278 )    qtRAllIkaLidqgy-mkq-ILVSNdW-LFgfSsyv---tnImdvMdrv-
d1itua-  ( 265 )    sqVAdHLdhIkev-AgarA-VGFGGdFDgVp-------------------
d1j5sa-  ( 373 )    fgMemhLkyLasvdlLynL-AGmvTdSr----------------------
d1j6oa-  ( 182 )    ealreVVkrV----g-ley-IVLETdC-PflpPqpf-------rg-----
d1m7ja3  ( 348 )    -depDvqrILaf---gp---TMIGSdGLPhD-e-----------------
d1nfga2  ( 293 )    kDhdvLWnaLrn---gv-F-eTVSSdHcsWl-fk--------ghKdrg-r
d1o12a2  ( 235 )    ---re-Vklvykv-KkAnG-IVLVTDSIsaA-glkdgtttlg------dl
d1onwa2  ( 261 )    VapAeGIArAvqagIplar-VTLSSdGngsg-------------------
d1p1ma2  ( 261 )    ---iApVqrMie----hgMkVTLGTdG-A---ASNn--------------
d1ra0a2  ( 292 )    rrGITrVkeMle----sgINVCFGHDG-V-fDpwyp--------------
d1un7a2  ( 261 )    ---plaAklAfla-Kgssk-LILITdSMrAK-glkdgvyeFG------gq
d1xrta2  ( 285 )    edrlalieGVkr---gI-I-dCFATdHAPhq-------------------
d1xwya1  ( 184 )    leLreLLplI----p-aek-LLIETdA-PyllPrdL---tpkpss-----
d1yixa1  ( 186 )    eqLrdAAryV----p-ldr-LLVETdS-pylAPvph-------rg-----
d1yrra2  ( 254 )    ---yanIrnAkrl-Kg-dk-LCLVTdATAPA-ganieqfifa------gk
d1zzma1  ( 189 )    -kTrdVIakL----p-las-LLLETdA-pdmpLngf-------qg-----
d2a3la1  ( 718 )    ---rNpFpvFFl----rGLnVSLSTdd-P---lqiH--------------
d2amxa1  ( 305 )    ---tHpIrkLyd----agVkVSVNSDD-P---GMFl--------------
d2dvta1  ( 267 )    ---tqtLidAile-Igadr-ILFSTdWPfen-------------------
d2eg6a1  ( 229 )    ihqqaLreLVas---gfnr-VFLGTdSaPha-rhrKes---s--------
d2f6ka1  ( 246 )    ---prqLptL-sl-Aqpeh-lLYGSdIPytp-------------------
d2ffia1  ( 213 )    aFArqALcaLeah-Ygaer--LWGSDwPHtq-he----------------
d2ftwa2  ( 305 )    rTkgvLMdyLar---gd-L-DCVGTdNctFc-a---------dqKamG-k
d2fvka2  ( 338 )    gtQksIWkGMnn---gT-F-tIVGSdHCsYn-yyekts---taSKhrA-f
d2gwga1  ( 264 )    ---qpgIdlLNtv-IpvdN-VLFAseigavr-gi----------------
d2hbva1  ( 274 )    ---pgaLelLvsv-Mgedr-VMLGSDyPFp--------------------
d2i9ua2  ( 302 )    ---mMpVrkYln----lgInVVLGSD--I---SAGh--------------
d2icsa2  ( 251 )    Fn-fhVAetAlreg---kA-aSISTDIyirN-re----------------
d2imra2  ( 334 )    ---tFdWpaFaa----agVeVALGTdS-v---ASGe--------------
d2ooda2  ( 306 )    ---lFrlGratdp---ehrVkSfGTD--V---GGGn--------------
d2p9ba2  ( 324 )    g-gvsGArqAhe----ag-LIGVGTdT-g---tfvp--------------
d2paja2  ( 320 )    -----pvreMad----agVpVSIGVDG-A---asNe--------------
d2puza2  ( 312 )    --qlPpvqaLrd----agAeIALATDC-N--PgtSp--------------
d2qeec1  ( 332 )    eiIneMTrmRMemlg-tsF-IPQHSdAr----------------------
d2qs8a2  ( 307 )    pqIsdtfrkaye----kgvkiAFGTdA-G---v-qk--------------
d2r8ca2  ( 303 )    gaGlhSIeiMkr----agVkmGFGTdL-L---G-eA--------------
d4ubpc2  ( 343 )    eTIAAEDiLHDl---GI-I-SMMSTDAl----------------------
                        aaaaaaa          b                            

                             760       770       780       790       800 
d1a4ma-  ( 302 )    --------------S------tLd-tDYqmTkkdm---------------
d1bf6a-  ( 254 )    ------------ggyG---YdyLLttFIpqLrqs----------------
d1gkpa2  ( 329 )    -----------eaFtaIPngipaIedRvnlLytyGvs-r-----------
d1gkra2  ( 326 )    -----------kdVwkAgngalgLetSlpmMltnGvn-k-----------
d1i0da-  ( 321 )    ------------Npdg---MAFIPlrVipfLrek----------------
d1itua-  ( 294 )    -rvPe-----------gLedVskYPdLIaeLlrr-nWt------------
d1j5sa-  ( 400 )    -------------------kLLSFgSRTeMFRRVLSNVVGemVekg----
d1j6oa-  ( 213 )    ------------krNe---PkyLk-yVvetISqvl---------------
d1m7ja3  ( 373 )    ------------------rpHpRLwgTFprVlghYSrdl-----------
d1nfga2  ( 328 )    -----------ndFraIpngapgVeeRlmmVyq-Gvn-e-----------
d1o12a2  ( 273 )    vVkVk-dgvPrledgtlAGStlfFsqAvknFrkfTgCs------------
d1onwa2  ( 304 )    ----------------vagFe-tLleTvqvLvkdydfs------------
d1p1ma2  ( 286 )    --------------s-----LnLf-fEmrlAsllQkaqnp----------
d1ra0a2  ( 322 )    --------------lG---tAnMl-qVLhmGlhvcqLmg-----------
d1un7a2  ( 299 )    sVtVr-grtAllsdgtlAGSiLkMneGarhMrefTnCs------------
d1xrta2  ( 311 )    ------------------tgiiGLqtAlpsAle-Lyr-k-----------
d1xwya1  ( 219 )    ------------rrNe---PahLp-hILqrIAhwR---------------
d1yixa1  ( 217 )    ------------keNq---PAmVr-dVAeyMAvlk---------------
d1yrra2  ( 291 )    tIyyr-nglCvdengtlsgSsLtMieGVrnLvehCgia------------
d1zzma1  ( 219 )    ------------qpNr---PeqAa-rVFavLcelR---------------
d2a3la1  ( 743 )    --------------lt---kepLv-eEYsiAAsvw---------------
d2amxa1  ( 330 )    --------------s------nIN-dNYekLyihl---------------
d2dvta1  ( 293 )    -----------------------IdhASdwFnaTs-Ia------------
d2eg6a1  ( 263 )    ---------------cgcagCFNAptALgSYAtVFeemn-----------
d2f6ka1  ( 272 )    --------------------ldgSrqlghaLattdllt------------
d2ffia1  ( 244 )    ----------------s---eVsFgsAveqFeaLg-Cs------------
d2ftwa2  ( 339 )    -----------ddFtkIPngvngVedRmsiVwenGvn-t-----------
d2fvka2  ( 378 )    d----pennknGeFryIpnglpgVctRmplLydyGyl-r-----------
d2gwga1  ( 293 )    ----------------dprtgfyyDdTkryIeaStiLt------------
d2hbva1  ( 299 )    ---------------------lGeqkIGglVlsSn-lg------------
d2i9ua2  ( 326 )    --------------t-----CsLf-kViayAiqNSkikwqesg-------
d2icsa2  ( 280 )    ----------------nGpVy-dLatT-ekLrvVg-Yd------------
d2imra2  ( 359 )    --------------t-----LnVr-eEvtfArqlyp--------------
d2ooda2  ( 332 )    --------------r-----fs-i-sVlddAykVG-cnntlldGsidpsr
d2p9ba2  ( 353 )    --------------q-----yaTw-rElelLvayAgFs------------
d2paja2  ( 343 )    --------------a-----AdMi-sEvhmTwlaQrar------------
d2puza2  ( 339 )    --------------l-----tsLl-lTmnmGatlFrMt------------
d2qeec1  ( 358 )    -------------------VLEQLIYKWhHSKsiIAeVLIdkyddilqag
d2qs8a2  ( 334 )    --------------H-----gtNw-kEfvy-ven--gp------------
d2r8ca2  ( 330 )    --------------q-----rlQs-dEfrILaev--Ls------------
d4ubpc2  ( 366 )    -------------------amGrageMvlrTwQTAdKMkkqrgplaeEkn
                                              aaaaaaa                 

                             810       820       830       840       850 
d1a4ma-  ( 316 )    ---------gFteeEFkrLN-inAAksSFLpeeek-----keL--lerLy
d1bf6a-  ( 273 )    ---------gFsqadVdvMLreNPsqFFq                     
d1gkpa2  ( 356 )    ---grL-d----ihrFvdAAstkAAklFglfp----rkGt-------iav
d1gkra2  ( 353 )    ---grL-s----lerLveVMcekPAklFgiyp----qkG           
d1i0da-  ( 340 )    ---------gVpqetLagItvtNParFLs----pt-----lra--s    
d1itua-  ( 319 )    ------------eaeVkgALAdNLLrVFeaVeqas--------------n
d1j5sa-  ( 427 )    -qipikeA----relVkhVSydgPkalFf                     
d1j6oa-  ( 232 )    ---------gvpeakVdeaTTenArrIFlevke                 
d1m7ja3  ( 394 )    ---glf-p----letAvwKMtgLTAakFgla-----erG           
d1nfga2  ( 354 )    ---grI-s----ltqfveLVAtrPAkvfgmfp----qkGt          
d1o12a2  ( 310 )    ------------itelakVSsyNSCvelgld-drG               
d1onwa2  ( 325 )    ------------isdAlrPLtsSVagfLnLtgkG                
d1p1ma2  ( 306 )    --------rnLdvntclkMVtydGAqAMgF--ksG               
d1ra0a2  ( 343 )    -----ygq----indGlnLIthhSarTLnlq-dyg-----iaa-------
d1un7a2  ( 336 )    ------------wtdIanITseNAAkqLgifdrkG               
d1xrta2  ( 341 )    ---giI-s----lkkLieMFtinPArIIgvd------lG           
d1xwya1  ( 238 )    ---------gedaawLaatTdanVktLFgiaf                  
d1yixa1  ( 236 )    ---------gvaveeLAqvTTdNFarLFhIdasrL-----qsi--r    
d1yrra2  ( 328 )    ------------ldeVlrMAtlYPArAIgvekrlG               
d1zzma1  ( 238 )    ---------repadeIAqaLlnnTytLFnVp                   
d2a3la1  ( 760 )    ---------kLsaCDLCeIA-rnSVyqSgFshalK-----shW--IgkdY
d2amxa1  ( 344 )    ---------nFtLeeFmiMN-nwAfekSFVsddvk-----seL--kalyF
d2dvta1  ( 307 )    ------------eadrvkIGrtnArrlFk-ld                  
d2eg6a1  ( 287 )    -------A----lqhFeaFCSvNGPqfYglpvndtfieLvreeqqva---
d2f6ka1  ( 290 )    ------------neqkqaIfydNAhrLlt-e                   
d2ffia1  ( 262 )    ------------aqlrqaLlldtaralFgFe                   
d2ftwa2  ( 366 )    ---gkL-t----wcqfvrATSserAriFniyp----rkGr          
d2fvka2  ( 412 )    ---gnLts----mmkLveIQctnPAkvYgmyp----qkGs          
d2gwga1  ( 315 )    ------------peekqqIYegNArrVYprLdaal--------------k
d2hbva1  ( 315 )    ------------esAkdkIisgnAskFFn-In                  
d2i9ua2  ( 349 )    -----kkdmfLstseAfyMATkkGGsfFg---kvG-----s         
d2icsa2  ( 300 )    ------------wpeiiekVtkaPAenFhltqkG                
d2imra2  ( 375 )    ---------gldprvLvrAAvkGGqrVVgtp                   
d2ooda2  ( 362 )    kdlaeAerNkLspyrgfwsvtlGGAeGLyIddklG-----n         
d2p9ba2  ( 371 )    ------------paeAlhAAtavNAsILgvdaetG-----s         
d2paja2  ( 361 )    ---------lAsiaeVihWGTAgGArVMgLd-evG-----k         
d2puza2  ( 357 )    ------------veeCltATtrnAAkALgllaetG-----t         
d2qeec1  ( 389 )    weVteeeI----krdVAdLFsrnFWrfVgrnd                  
d2qs8a2  ( 351 )    ------------a-kaiqsAt-etakllriedklg               
d2r8ca2  ( 346 )    ------------paeViaSAtivSAeVLgmqdklG               
d4ubpc2  ( 397 )    g--sdnfR----lkrYvSKytiNPAiAQgIah----eVGsieegkfadgd
                                aaaaaaaa aaaaaa                       

                             860       870       880       890       900 
d1a4ma-  ( 349 )    reYq                                              
d1bf6a-                                                               
d1gkpa2  ( 387 )    gSd                                               
d1gkra2                                                               
d1i0da-                                                               
d1itua-  ( 343 )    ltqapeeepIpldqlggscrthy---------------------------
d1j5sa-                                                               
d1j6oa-                                                               
d1m7ja3                                                               
d1nfga2                                                               
d1o12a2                                                               
d1onwa2                                                               
d1p1ma2                                                               
d1ra0a2  ( 371 )    --------------------------------------------------
d1un7a2                                                               
d1xrta2                                                               
d1xwya1                                                               
d1yixa1                                                               
d1yrra2                                                               
d1zzma1                                                               
d2a3la1  ( 793 )    ykrg-----------------------------pdGNdIhkTNVPHIRve
d2amxa1                                                               
d2dvta1                                                               
d2eg6a1  ( 323 )    ------esialt--------------ddtLvPFlagetvr-Wsvk     
d2f6ka1                                                               
d2ffia1                                                               
d2ftwa2                                                               
d2fvka2                                                               
d2gwga1  ( 339 )    akgk                                              
d2hbva1                                                               
d2i9ua2                                                               
d2icsa2                                                               
d2imra2                                                               
d2ooda2                                                               
d2p9ba2                                                               
d2paja2                                                               
d2puza2                                                               
d2qeec1                                                               
d2qs8a2                                                               
d2r8ca2                                                               
d4ubpc2  ( 486 )    lihdtnITFMSksSiqqgvpakLgLkRriGtVknCrnigKkdMkwNdvtt
                                                                      

                             910       920       930   
d1a4ma-                                                
d1bf6a-                                                
d1gkpa2                                                
d1gkra2                                                
d1i0da-                                                
d1itua-  ( 366 )    -------------------------------gyss
d1j5sa-                                                
d1j6oa-                                                
d1m7ja3                                                
d1nfga2                                                
d1o12a2                                                
d1onwa2                                                
d1p1ma2                                                
d1ra0a2  ( 371 )    ------------------------------gnsan
d1un7a2                                                
d1xrta2                                                
d1xwya1                                                
d1yixa1                                                
d1yrra2                                                
d1zzma1                                                
d2a3la1  ( 814 )    Fr--dtIwke-------EmqqVYlgkavisdevvp
d2amxa1                                                
d2dvta1                                                
d2eg6a1                                                
d2f6ka1                                                
d2ffia1                                                
d2ftwa2                                                
d2fvka2                                                
d2gwga1                                                
d2hbva1                                                
d2i9ua2                                                
d2icsa2                                                
d2imra2                                                
d2ooda2                                                
d2p9ba2                                                
d2paja2                                                
d2puza2                                                
d2qeec1                                                
d2qs8a2                                                
d2r8ca2                                                
d4ubpc2  ( 536 )    dIdInpetyeVkvdgevltcepvkelpmaqryflf
                                                       

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla ç
positive phi: italic x

Jmol view

Jmol Model View
Jmol Command prompt
Response Logs

Tree based on RMSD between structures

Matrices

1. Percentage Identity Matrix  [View | Download]
2. Distance Matrix  [View | Download]

PCA based on sequence identity

1. PCA  [View]
2. Plot file  [Download]

CUSP Results

CUSP Result   [View | Download]

Alistat - Alignment Statistics

Alignment Statistics  [Download]

SMotif - Conserved Structural Motifs

SMotif Result   [View | Download]

MeanRMS

MeanRMS  [Download]