PASS2
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Superfamily Details

Superfamily summary
Superfamily Name:  NAD(P)-linked oxidoreductase
Class Name:  Alpha and beta proteins (a/b)
Fold Name:  TIM beta/alpha-barrel
Number of Members:  8
Average Size: 
Members
SCOP ID Name Source
d3eaua1 Voltage-dependent K+ channel beta subunit Rat (Rattus norvegicus) [TaxId: 10116]
d1gvea- Aflatoxin aldehyde reductase (akr7a1) Rat (Rattus norvegicus) [TaxId: 10116]
d1us0a- Aldose reductase (aldehyde reductase) Human (Homo sapiens) [TaxId: 9606]
d1mzra- 2,5-diketo-D-gluconic acid reductase A Escherichia coli [TaxId: 562]
d1ur3m- Hypothetical oxidoreductase YdhF Escherichia coli [TaxId: 562]
d1pyfa- Putative oxidoreductase IolS Bacillus subtilis [TaxId: 1423]
d1pz1a- Putative oxidoreductase YhdN Bacillus subtilis [TaxId: 1423]
d1lqaa- Tas protein Escherichia coli [TaxId: 562]

Alignment Based On Similarities In Structural Features using Comparer

                             10        20        30        40        50  
d1gvea-  (   4 )                 arPaTVLgAm-EMgrrM----dvtsSsrSVraFlqrg
d1lqaa-  (   1 )     Mq-yhrIphSsLeVStLGLgTm-TFGeqN----seadAhaQLdyAvaqg
d1mzra-  (   3 )    anptvik-LqdgnvMpQLGLGVwqas---------neeVitAIqkALevg
d1pyfa-  (   2 )       kkakLgksdlqVfpIgLgTnAVGGhnlypnlneetGkeLVreAirng
d1pz1a-  (  28 )                                  wggtdektsietiraaLdqg
d1ur3m-  (   1 )     lVqritIApqGpeFSrFv-gywrls---------arqlvsfIeeHLdlG
d1us0a-  (   0 )    ma-sril-LnngakMpiLGLgTwkSp---------pgqVteAVkvAIdvg
d3eaua1  (  36 )     lqfyrnLGksglrVSCLGLgTwvTFggqi----tdemAehLMtlAydng
                         bb      bb                    aaaaaaaaaaaaa  

                             60        70        80        90        100 
d1gvea-  (  36 )    hteIDTAfvya-------nGqSEtILGdl--glg----LGrsgckvkIaT
d1lqaa-  (  44 )    InLIDVAEmyPvpprpetqGlTEtyVGnWLakhg-----sre--kLIIAS
d1mzra-  (  43 )    YrSIDTAaay----------kNEeGVGkALkna----svnre--eLfITT
d1pyfa-  (  49 )    VtL-dTAyiyG-------iGrSEeLIGeVLref------nre--dVvIaT
d1pz1a-  (  48 )    itlidTApayg-------fgqsEeivGkAikey------krd--qViLAT
d1ur3m-  (  46 )    VtTvDHAdiyggy-------qceaaFGeALkla----phLre--r-eIVS
d1us0a-  (  39 )    YrHIDCAhvy----------qNEneVGvAIqeklreqvVkre--eLFIVS
d3eaua1  (  81 )    InLFDTAEvya-------aGkAEvvLGnIikkkg----wrrs--sLVITT
                      bbb                aaaaaaaaaaa        33  3 bbbb

                             110       120       130       140       150 
d1gvea-  (  73 )    KAAPm---f----------gktLkpadVrfQLetSlkrLqCprVdLFYLh
d1lqaa-  (  87 )    KVSGp---srnndkgiRp-dQaLdrknIreALhdSlkrLqtdyLDLYQVh
d1mzra-  (  77 )    KLw--nddHk----------------rpreaLldSLkkLqldyIdLYLMh
d1pyfa-  (  84 )    KaAhr---kqgndfvf-----dNspdfLkksvdeSlkrLntdYIDLFYIh
d1pz1a-  (  84 )    KTALd---wknnqlfr-----hAnrarIveEVenSlkrLqtdyIdlYQvh
d1ur3m-  (  83 )    KCGiAttareeNvighy----iTdrdhIiksAeqSlinLatdhLdLLLIH
d1us0a-  (  77 )    KLW--CTyHek--------------glVkgaCqkTLsdLkLdyLdLYLIh
d3eaua1  ( 118 )    KIFwg---g------kaetergLsrkHIiegLkaSlerLqleyVdVVFAn
                    bb                      aaaaaaaaaaaaaaa      bbbb 

                             160       170       180       190       200 
d1gvea-  ( 110 )    fPdh-------------------gTpieeTLqaChqLhqegkFveLGLSN
d1lqaa-  ( 133 )    wPqr--pTncfgklgyswtdsapavslldTLdALaeYqragkIryIGVSN
d1mzra-  ( 109 )    WPVpa------------------idhYVeAWkgMieLqkeglIkSIGVCN
d1pyfa-  ( 126 )    fpde-------------------htpKdeAVnALn-ekkagkIrSIGVSn
d1pz1a-  ( 126 )    wpDp-------------------lVpieetAeVke-lydagkIraiGVSn
d1ur3m-  ( 129 )    rpdp--------------------ldAdeVAdAFkhLhqsgkVrhFGVSn
d1us0a-  ( 111 )    wPTGFkpgkeffPldesgnVvpsdtnIldTWaaMeeLvdeglVkAIGISN
d3eaua1  ( 159 )    rpdp-------------------nTpmeeTVrAMthVinqgmAmyWGTSr
                                              aaaaaaaaaaaaa      bbbb 

                             210       220       230       240       250 
d1gvea-  ( 141 )    YvsweVaeICtlCkkngwimPtVYQGMYNAITrq-VeteLFpcLrhfgLr
d1lqaa-  ( 181 )    EtafGVmrYLhLAdkhdlprIVTIQnpYSLLNrs-FevglaevSqyegVe
d1mzra-  ( 141 )    FqihHLqrLide----tgvtPvINQIELHPLmQqr---qLhawNathkIq
d1pyfa-  ( 157 )    FsleqLkeANkd------glVdVLqgeYNLlnRe-AektfFpyTkehnIS
d1pz1a-  ( 157 )    fsieq-dtFrav------AplhtiQppYNLFere--eesvlpyAkdnkIt
d1ur3m-  ( 160 )    ftpaqFalLqs----rLpftLAtNqVeIsPvhqpllldgTldqLqqlrVr
d1us0a-  ( 161 )    FnhlqVemIlnkp--glkykPAVNQIECHPYLTqe---klIqyCqskgIv
d3eaua1  ( 190 )    WssmeImeAysvArqfnlipPiCEQAeYHMfqRekVevqLpeLfhkIgVG
                      aaaaaaaa            bbbbb            aaaaaaa   b

                             260       270       280       290       300 
d1gvea-  ( 190 )    FYAfnplAggLLtgrYkyqdkdgknpeSrFfgNpfsqlymdRYWk---ee
d1lqaa-  ( 230 )    LLAysClGfgtLtGkylnga---kpagarntl--f-srf-trYsg---eq
d1mzra-  ( 184 )    TESWsPlAq----gGk----------------------------------
d1pyfa-  ( 200 )    FIPyfplVsgLLAGkytedt--tfpegdlrne-------qehFkgerFke
d1pz1a-  ( 200 )    TLLygSlCrgLLtgk-teey--tfegdDlrnh-------DpKFqkprfke
d1ur3m-  ( 206 )    -PAwsclgggrlf---------------------------------nddy
d1us0a-  ( 206 )    VTAysPlgspdRpwak------------------------------pedp
d3eaua1  ( 240 )    AMTwsPlAcgIVsgkYdsg----ippysrAslkgy-qwLkdkIlseeGrr
                    bbbb                                              

                             310       320       330       340       350 
d1gvea-  ( 237 )    HfnGialVekaLkttygptapsMiSAAVrWMYhhSqLkgtqgdAVILgMs
d1lqaa-  ( 270 )    TqkAVaaYVdIArrhg----ldpaqMALAFVrrq-----pfVASTLLgAt
d1mzra-  ( 196 )    gVfdqkvIrdladkygk----tpaqIVIrWHLDs-------gLVVIPksv
d1pyfa-  ( 241 )    nIrkVnkLapiAek-h---nvdipHIVLAWYlar-----peIdiLiPgak
d1pz1a-  ( 241 )    YlsAvnqLdklAktry---gksVihLAvrWIldq-----pgAdialwgar
d1ur3m-  ( 223 )    fqpLrdeLavVaeelnAg---sieqVvNaWVlrLpS-----qPLPiigsg
d1us0a-  ( 226 )    sLledprIkaiAakhnk----ttaqVLIRFPMqr-------nLVVIPksv
d3eaua1  ( 285 )    qqakLkeLqaIAerlg----ctLpqLAIAWCLrn-----egVsSVLLgAs
                     aaaaaaaaaaaaa        aaaaaaaaaa           bb     

                             360       370       380       390       400 
d1gvea-  ( 287 )    sleqLeqNLalVeeg-pLepaVvdAFdqAwnlVaheCpnYfr        
d1lqaa-  ( 311 )    tmdqLktNieSlhl--eLsedVlaeIeavhqvytypAp            
d1mzra-  ( 235 )    tpsrIaeNfdVwdf--rLdkdelgeIakldq--gkrlgpdPdqfgg    
d1pyfa-  ( 282 )    radqLidnikTadV--tLsqedisfIdklFap------------------
d1pz1a-  ( 283 )    kpgqLealseitgw--tLnseDqkdIntilentisdpvgpefapptreei
d1ur3m-  ( 265 )    kierVraAveAetl--k-trqqwfrIrkaAl--gyd--------------
d1us0a-  ( 265 )    tperIaeNfkVfdf--eLssqDmttLlsynr--nwrVcallsctsHkdyP
d3eaua1  ( 326 )    naeqLmeNigAiqVlpkLsssivheIdsiLg--nkpys            
                     aaaaaaaa          aaaaaaaaaa                     

                      
d1gvea-               
d1lqaa-               
d1mzra-               
d1pyfa-  ( 312 )    -g
d1pz1a-  ( 332 )    pg
d1ur3m-  ( 297 )    -v
d1us0a-  ( 311 )    fh
d3eaua1               
                      

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla ç
positive phi: italic x

Jmol view

Jmol Model View
Jmol Command prompt
Response Logs

Tree based on RMSD between structures

Matrices

1. Percentage Identity Matrix  [View | Download]
2. Distance Matrix  [View | Download]

PCA based on sequence identity

1. PCA  [View]
2. Plot file  [Download]

CUSP Results

CUSP Result   [View | Download]

Alistat - Alignment Statistics

Alignment Statistics  [Download]

SMotif - Conserved Structural Motifs

SMotif Result   [View | Download]

MeanRMS

MeanRMS  [Download]