PASS2
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Superfamily Details

Superfamily summary
Superfamily Name:  Inosine monophosphate dehydrogenase (IMPDH)
Class Name:  Alpha and beta proteins (a/b)
Fold Name:  TIM beta/alpha-barrel
Number of Members:  3
Average Size: 
Members
SCOP ID Name Source
d1zfja1 Inosine monophosphate dehydrogenase (IMPDH) Streptococcus pyogenes [TaxId: 1314]
d1pvna1 Inosine monophosphate dehydrogenase (IMPDH) Tritrichomonas foetus [TaxId: 5724]
d1jr1a1 Inosine monophosphate dehydrogenase (IMPDH) Chinese hamster (Cricetulus griseus) [TaxId: 10029]

Alignment Based On Similarities In Structural Features using Comparer

                             10        20        30        40        50  
d1jr1a1  (  17 )    gltAqqLFncgdgltYndFlilpgyi--dFtadqVdLtSaLTk-------
d1pvna1  (   2 )    akyyn-----epchtFneyllipglstvdCipsnVnLsTpLVkfqkgqqS
d1zfja1  (   2 )    s--nwdtkflkkGytFddVllipaes--hvlpnevdLktkLad-------
                                   333 bb          333    bb          

                             60        70        80        90        100 
d1jr1a1  (  58 )    kitLkTPLVSSPmdtVTeagMAiAMALtGGIGFIHhnctpefQanEVrkV
d1pvna1  (  47 )    einLkiPLVSaImqSVSgekMAiaLAregGISFIfgsqsiesQaamVhaV
d1zfja1  (  41 )    nLtLnIPIItaa-dTVTgsk-AiaIAragGLGvIhkn-siteQAeeVrkV
                      bb    bb            aaaaa   bbbb     aaaaaaaaaaa

                             110       120       130       140       150 
d1jr1a1  ( 108 )    KkyeqyplAskdakkqLlCGAAIgtheddkyrLdlLalagVdVVVLdssq
d1pvna1  (  97 )    knf------------rylVGAGInt-rdFreRVpaLveagAdVLCIdssd
d1zfja1  (  91 )    Krse----------grllVAAAVgvtsdTferAeaLFeAgAdAIVIdtah
                    a                  bbbb     aaaaaaaaaaa   bbbb    

                             160       170       180       190       200 
d1jr1a1  ( 278 )    GnsifQinMIkyMkekyp-nlqVIGGnVvtaaqAknLidAgVdALrVGmG
d1pvna1  ( 265 )    GfsewQkiTIgwIrekygdkvkVGAGNIvdgeGFryLAdAgADFIKIGiG
d1zfja1  ( 257 )    GhsagVlrkIaeIrahfp-nrTLIAGnIataeGAraLYdagVdVVkVGiG
                       aaaaaaaaaaaaa      bbbbbb  aaaaaaaaa    bbbb   

                             210       220       230       240       250 
d1jr1a1  ( 327 )    cgsiciTqevlacGrpQAtAVYkVSeyArrf------gVpVIAdggIqnv
d1pvna1  ( 315 )    ggsiciTreqkgiGrgQAtAVidVvaeRnkyfeetgiyIPVCSdggIvyd
d1zfja1  ( 306 )    pgsicttrvvagvgvpQVtAIydAaaVArey------gktIiAdggIkys
                          aaaa      aaaaaaaaaaaa            bbb      a

                             260       270       280       290       300 
d1jr1a1  ( 371 )    gHIakALALGAsTVMMgslLAATteApgeyffsdgirlKkYrGmgSldAm
d1pvna1  ( 365 )    yHMTLALAMgADFIMLGryFArFeeSpTrkvtingsvmKeYwGEGSsrAr
d1zfja1  ( 350 )    gDiVkALAAgGnAV-lgs-FAGTdeApGeteiyqgrkyktyrg-gSiaak
                    aaaaaaaa                      bb    bbbbbb        

                             310       320       330       340       350 
d1jr1a1  ( 437 )    i------------kvaqGvsgavqdkgsIhkfVpyLiagIqhsCqdiGAk
d1pvna1  ( 415 )    NwqrydlggkqklsfeEGvdsyvpyagkLkdnVeaSlnkVkstMcnCGAl
d1zfja1  ( 401 )    knkl----------vpeGiegrvaykgaasdiVf-qlggIrsgG-yVGag
                                       bbbbb    aaaaaa   aaaaa        

                             360       370       380       390 
d1jr1a1  ( 475 )    sLtqVramMysgeLkFekrtssaqveggvhslhsyekrlf  
d1pvna1  ( 465 )    tIpqLqs-----kAkitlvssvsiveggahdvivk       
d1zfja1  ( 455 )    diqelhen-----Aqfve-sgaglieshphdvqitneapnys
                     aaaaaa        bb   aaaaaaa               

solvent inaccessible: UPPER CASE X
solvent accesible: lower case x
alpha helix: red x
beta strand: blue x
3 - 10 helix: maroon x
hydrogen bond to main chain amide: bold x
hydrogen bond to mainchain carbonyl: underline x
disulphide bond: cedilla ç
positive phi: italic x

Jmol view

Jmol Model View
Jmol Command prompt
Response Logs

Tree based on RMSD between structures

Matrices

1. Percentage Identity Matrix  [View | Download]
2. Distance Matrix  [View | Download]

PCA based on sequence identity

1. PCA  [View]
2. Plot file  [Download]

CUSP Results

CUSP Result   [View | Download]

Alistat - Alignment Statistics

Alignment Statistics  [Download]

SMotif - Conserved Structural Motifs

SMotif Result   [View | Download]

MeanRMS

MeanRMS  [Download]