NCBS - IWS
National Centre for Biological Sciences - Integrated Web Server (NCBS-IWS) is an integrated bioinformatics work bench dedicated for complete in-silico analysis of protein sequence and structure data based on various strategies. Currently NCBS-IWS provides tools for 10 in-silico analysis categories. NCBS-IWS provides web interface to both in-house and widely accepted programs from major bioinformatics groups also. NCBS-IWS also provides interactive images for Analysis Work Flow, that will help the user to carry out analysis in an easy way.
MODIP Online @ NCBS - IWS(help)
1. Upload or Paste the Coordinates file in PDB format
2. Format includes HEADER, COMPND, SOURCE, AUTHOR and ATOM
3. PDB file can be single chain or multi chain.
4. 'C-alpha only' proteins are not useful for running MODIP.
Alternatively you can also submit your sequence by using the
following method :
MODIP / DSDBASE Reference :
R.Sowdhamini, N.Srinivasan, B.Shoichet, D.V.Santi, C.Ramakrishnan and P.Balaram (1989). Stereochemical modelling of disulfide bridges: Criteria for introduction into proteins by site-directed mutagenesis. Prot. Engng., 3, 95-103.
Thangudu, R. R., Vinayagam, A., Pugalenthi, G.,Manonmani, A., Offmann, B. & Sowdhamini, R. (2005) Native and modelled disulphide bonds in proteins: Knowledge-based approaches towards structure prediction of disulphide-rich polypeptides. Proteins: Structure Function and Bioinformatics, 58, 866-79.
Dr. R. Sowdhamini (email@example.com)