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SCOP Superfamily codeNo of genomesPruned sequencesTotal sequencesSuperfamily name
46458
746
2440
3797
Globin-like
46548
161
401
523
alpha-helical ferredoxin
46557
77
112
208
GreA transcript cleavage protein, N-terminal domain
46561
116
143
190
Ribosomal protein L29 (L29p)
46565
194
485
1153
Chaperone J-domain
46575
6
7
16
Theta subunit of DNA polymerase III
46579
78
272
451
Prefoldin
46585
18
38
82
Effector domain of the protein kinase pkn/prk1
46589
137
364
529
tRNA-binding arm
46596
65
122
230
Eukaryotic DNA topoisomerase I, dispensable insert domain
46600
97
184
233
C-terminal UvrC-binding domain of UvrB
46604
28
34
68
Epsilon subunit of F1F0-ATP synthase C-terminal domain
46609
366
531
1157
Fe,Mn superoxide dismutase (SOD), N-terminal domain
46626
305
855
1390
Cytochrome c
46689
564
3864
6653
Homeodomain-like
46767
113
196
402
Methylated DNA-protein cysteine methyltransferase, C-terminal domain
46774
19
78
191
ARID-like
46785
463
3298
4148
"Winged helix" DNA-binding domain
46894
193
1209
1817
C-terminal effector domain of the bipartite response regulators
46906
143
198
350
Ribosomal protein L11, C-terminal domain
46911
118
141
270
Ribosomal protein S18
46915
87
97
137
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
46919
35
464
1258
N-terminal Zn binding domain of HIV integrase
46924
33
37
76
RNA polymerase subunit RPB10
46929
19
20
40
DNA helicase RuvA subunit, C-terminal domain
46934
113
152
314
UBA-like
46938
26
149
226
N-terminal domain of phosphatidylinositol transfer protein sec14p
46942
17
53
81
Elongation factor TFIIS domain 2
46946
163
198
366
S13-like H2TH domain
46950
35
40
74
Hypothetical protein MTH1615
46955
168
443
578
Putative DNA-binding domain
46966
70
305
610
Spectrin repeat
46973
33
71
158
Enzyme IIa from lactose specific PTS, IIa-lac
46977
118
229
408
Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
46984
6
11
42
Smac/diablo
46988
18
33
56
Tubulin chaperone cofactor A
46992
92
103
134
Ribosomal protein S20
46997
17
40
76
Bacterial immunoglobulin/albumin-binding domains
47005
114
227
506
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
47014
8
15
24
Protozoan pheromone proteins
47027
46
104
247
Acyl-CoA binding protein
47031
37
149
464
Second domain of FERM
47040
9
16
50
Kix domain of CBP (creb binding protein)
47045
7
7
21
alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
47050
14
41
141
Thermostable subdomain from chicken villin headpiece
47055
3
3
12
TAF(II)230 TBP-binding fragment
47060
169
446
1082
S15/NS1 RNA-binding domain
47072
2
4
11
p8-MTCP1
47077
8
18
56
T4 endonuclease V
47082
32
43
85
Fertilization protein
47090
103
373
533
PGBD-like
47095
206
683
1557
HMG-box
47113
342
1228
2324
Histone-fold
47144
25
32
56
HSC20 (HSCB), C-terminal oligomerisation domain
47148
13
14
31
Diol dehydratase, gamma subunit
47152
12
19
37
Methane monooxygenase hydrolase, gamma subunit
47157
11
22
48
Mitochondrial import receptor subunit Tom20
47162
55
129
240
Apolipoprotein
47170
11
24
58
Aspartate receptor, ligand-binding domain
47175
59
88
166
Cytochromes
47188
43
108
138
Hemerythrin
47195
30
88
210
TMV-like viral coat proteins
47203
86
427
770
Acyl-CoA dehydrogenase C-terminal domain-like
47212
12
14
66
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
47216
11
27
29
Proteasome activator reg(alpha)
47220
37
92
215
alpha-catenin/vinculin
47226
91
277
356
Histidine-containing phosphotransfer domain, HPT domain
47233
23
35
75
Bacterial GAP domain
47240
370
897
1364
Ferritin-like
47266
221
903
1534
4-helical cytokines
47323
148
641
1063
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
47336
215
534
830
ACP-like
47345
7
33
70
Colicin E immunity proteins
47353
63
913
2918
Retrovirus capsid protein C-terminal domain
47364
147
340
758
Domain of the SRP/SRP receptor G-proteins
47370
38
202
391
Bromodomain
47380
13
22
42
ROP protein
47384
119
420
528
Homodimeric domain of signal transducing histidine kinase
47391
18
33
79
Dimerization-anchoring domain of cAMP-dependent type II PK regulatory subunit
47396
15
34
58
Transcription factor IIA (TFIIA), N-terminal domain
47401
1
1
3
Ectatomin, A & B chains
47406
12
20
54
SinR repressor dimerisation domain-like
47413
191
834
1215
lambda repressor-like DNA-binding domains
47446
135
152
353
Signal peptide-binding domain
47454
11
25
97
A DNA-binding domain in eukaryotic transcription factors
47459
120
478
843
Helix-loop-helix DNA-binding domain
47473
313
1408
2385
EF-hand
47565
59
188
317
Insect pheromon/odorant-binding proteins
47571
8
10
30
Cloroperoxidase
47576
55
366
886
Calponin-homology domain, CH-domain
47587
24
38
124
Domain of poly(ADP-ribose) polymerase
47592
10
18
63
MDM2
47598
25
34
53
Met repressor-like
47610
33
47
114
Disulphide-bond formation facilitator (DSBA), insertion domain
47616
219
934
1914
Glutathione S-transferase (GST), C-terminal domain
47644
71
135
224
Methionine synthase domain
47648
109
185
258
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
47655
30
93
216
STAT
47661
64
227
412
t-snare proteins
47668
8
19
73
N-terminal domain of cbl (N-cbl)
47672
15
32
81
Transferrin receptor ectodomain, C-terminal domain
47676
16
54
69
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
47681
7
7
15
C-terminal domain of B transposition protein
47686
21
58
97
Anaphylotoxins (complement system)
47694
12
24
62
Cytochrome c oxidase subunit h
47699
112
433
605
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
47719
35
48
152
p53 tetramerization domain
47724
24
30
52
Domain of early E2A DNA-binding protein, ADDBP
47729
136
284
557
IHF-like DNA-binding proteins
47741
82
215
466
CO dehydrogenase ISP C-domain like
47752
4
4
10
Protein HNS-dependent expression A; HdeA
47757
42
63
98
Chemotaxis receptor methyltransferase CheR, N-terminal domain
47762
13
41
114
PAH2 domain
47769
41
248
532
SAM/Pointed domain
47781
138
363
591
RuvA domain 2-like
47789
147
165
300
C-terminal domain of RNA polymerase alpha subunit
47794
122
206
323
DNA repair protein Rad51, N-terminal domain
47798
8
12
27
Barrier-to-autointegration factor, BAF
47802
41
55
173
DNA polymerase beta, N-terminal domain-like
47807
159
233
379
5' to 3' exonuclease, C-terminal subdomain
47819
25
30
46
HRDC-like
47823
98
209
266
lambda integrase-like, N-terminal domain
47831
94
140
251
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
47836
137
1631
3073
Retroviral matrix proteins
47852
20
418
1000
Hepatitis B viral capsid (hbcag)
47857
100
228
363
Apolipophorin-III
47862
36
63
119
Saposin
47869
1
3
11
Bacteriocin AS-48
47874
73
264
526
Annexin
47895
117
349
741
Transducin (alpha subunit), insertion domain
47912
26
78
138
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
47917
1497
1871
2813
C-terminal domain of alpha and beta subunits of F1 ATP synthase
47923
18
211
310
Ypt/Rab-GAP domain of gyp1p
47928
121
137
184
N-terminal domain of the delta subunit of the F1F0-ATP synthase
47933
19
24
43
Endoplasmic reticulum protein ERP29, C-domain
47938
12
16
25
Functional domain of the splicing factor Prp18
47943
80
2142
3692
Retrovirus capsid protein, N-terminal core domain
47954
182
634
1223
Cyclin-like
47973
202
306
560
Ribosomal protein S7
47979
64
96
179
Iron-dependent represor protein, dimerization domain
47986
67
276
657
DEATH domain
48008
10
10
34
Fatty acid responsive transcription factor FadR, C-terminal domain
48013
94
181
305
Antitermination factor NusB
48019
118
245
355
DNA polymerase III clamp loader subunits, C-terminal domain
48024
106
126
250
N-terminal domain of DnaB helicase
48029
50
58
123
FliG
48034
63
105
252
Guanido kinase N-terminal domain
48045
8
10
25
Scaffolding protein gpD of bacteriophage procapsid
48050
65
180
328
Hemocyanin, N-terminal domain
48056
130
303
534
Di-copper centre-containing domain
48065
27
215
558
DBL homology domain (DH-domain)
48076
14
17
46
LigA subunit of an aromatic-ring-opening dioxygenase LigAB
48081
55
235
396
Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
48092
14
51
160
Transcription factor STAT-4 N-domain
48097
24
191
581
Regulator of G-protein signalling, RGS
48108
129
165
351
Carbamoyl phosphate synthetase, large subunit connection domain
48113
117
544
1309
Heme-dependent peroxidases
48140
46
85
180
Ribosomal protein L19 (L19e)
48145
12
142
537
Influenza virus matrix protein M1
48150
116
316
702
DNA-glycosylase
48163
126
164
237
An anticodon-binding domain of class I aminoacyl-tRNA synthetases
48168
137
172
269
R1 subunit of ribonucleotide reductase, N-terminal domain
48173
94
185
370
Cryptochrome/photolyase FAD-binding domain
48179
267
799
1361
6-phosphogluconate dehydrogenase C-terminal domain-like
48201
17
53
75
Uteroglobin-like
48208
182
567
878
Six-hairpin glycosyltransferases
48225
22
71
241
Seven-hairpin glycosyltransferases
48230
42
59
134
Chondroitin AC/alginate lyase
48239
161
487
788
Terpenoid cylases/Protein prenyltransferases
48256
178
275
659
Citrate synthase
48264
330
1725
2974
Cytochrome P450
48283
96
353
444
FIS-like
48295
15
17
48
TrpR-like
48300
105
113
168
Ribosomal protein L7/12, oligomerisation (N-terminal) domain
48305
8
12
37
MHC class II-associated invariant chain ectoplasmic trimerization domain
48310
19
49
105
Aldehyde ferredoxin oxidoreductase, C-terminal domains
48317
109
245
339
Acid phosphatase/Vanadium-dependent haloperoxidase
48329
133
235
474
RNA polymerase sigma subunit
48334
113
229
467
DNA repair protein MutS, domain III
48340
73
246
447
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
48345
28
105
212
A virus capsid protein alpha-helical domain
48350
35
293
739
GTPase activation domain, GAP
48366
19
162
279
Ras GEF
48371
103
696
1183
ARM repeat
48403
121
810
1749
Ankyrin repeat
48425
21
89
247
Sec7 domain
48435
53
93
131
Bacterial muramidases
48439
62
295
425
Protein prenylyltransferase
48445
77
253
577
14-3-3 protein
48452
121
605
805
TPR-like
48464
23
175
406
ENTH/VHS domain
48473
16
92
205
Phosphoinositide-binding clathrin adaptor, N-terminal domain
48479
12
14
47
Cytochrome c oxidase subunit E
48484
66
192
387
Lipoxigenase
48493
15
15
29
gene 59 helicase assembly protein
48498
37
67
120
Tetracyclin repressor-like, C-terminal domain
48503
28
96
202
Skp1-Skp2 dimerisation domains
48508
159
777
1812
Nuclear receptor ligand-binding domain
48537
43
71
162
Phospholipase C/P1 nuclease
48547
24
136
532
Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b
48552
51
100
237
Serum albumin-like
48557
218
583
1143
L-aspartase-like
48576
244
649
1056
Terpenoid synthases
48592
379
729
1438
GroEL equatorial domain-like chaperone equatorial domain
48600
100
152
208
Chorismate mutase II
48608
5
15
47
Peridinin-chlorophyll protein
48613
65
105
188
Heme oxygenase
48619
124
440
780
Phospholipase A2, PLA2
48647
14
40
80
Fungal elicitin
48652
13
19
35
Tetraspanin
48657
8
24
67
Repressor of bacterial conjugation FinO
48662
30
40
63
Ribosomal protein L39e
48666
9
11
22
Methanol dehydrogenase subunit
48670
17
68
139
Transducin (heterotrimeric G protein), gamma chain
48674
28
39
51
Fe-only hydrogenase smaller subunit
48678
36
71
148
Moesin tail domain
48682
6
12
32
Nuclear receptor coactivator Src-1
48686
2
5
11
Proteinase A inhibitor IA3
48690
15
20
43
Epsilon subunit of mitochondrial F1F0-ATP synthase
49265
115
720
1550
Fibronectin type III
49299
16
72
97
PKD domain
49303
76
144
349
beta-Galactosidase/glucuronidase domain
49309
30
64
145
Transglutaminase, two C-terminal domains
49313
36
361
882
Cadherin
49319
20
25
51
Actinoxanthin-like
49329
216
348
743
Cu,Zn superoxide dismutase-like
49344
24
31
81
CBD9-like
49348
11
32
106
Clathrin adaptor appendage domain
49354
57
300
607
PapD-like
49363
24
63
106
Purple acid phosphatase, N-terminal domain
49367
21
23
51
Superoxide reductase-like
49373
50
125
264
Invasin/intimin cell-adhesion fragments
49380
5
5
20
Diphtheria toxin, C-terminal domain
49384
122
303
458
Carbohydrate-binding domain
49401
43
251
380
Bacterial adhesins
49410
33
115
199
Alpha-macroglobulin receptor domain
49417
109
486
1389
p53-like transcription factors
49441
50
55
123
Cytochrome f, large domain
49447
26
93
206
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
49452
78
118
248
Starch-binding domain
49464
39
101
186
Carboxypeptidase D, a regulatory domain
49468
6
7
21
VHL
49472
48
66
150
Transthyretin (prealbumin)
49478
14
21
51
B repeat unit of collagen binding surface protein (cna)
49482
63
159
334
Aromatic compound dioxygenase
49493
150
256
376
HSP40/DnaJ peptide-binding domain
49498
11
11
21
alpha-Amylase inhibitor tendamistat
49503
1802
2733
4453
Cupredoxins
49562
74
530
1229
C2 domain (Calcium/lipid-binding domain, CaLB)
49584
23
124
203
Periplasmic chaperone C-domain
49590
42
195
292
PHL pollen allergen
49594
4
6
14
Rab geranylgeranyltransferase alpha-subunit, insert domain
49599
25
233
388
TRAF domain-like
49606
51
103
215
Neurophysin II
49611
301
1700
3264
Viral coat and capsid proteins
49695
65
225
471
gamma-Crystallin-like
49723
77
250
504
Lipase/lipooxygenase domain (PLAT/LH2 domain)
49742
24
62
143
PHM/PNGase F
49749
51
196
382
Viral proteins
49758
29
96
284
Calpain large subunit, middle domain (domain III)
49764
179
448
671
HSP20-like chaperones
49772
12
20
49
Ecotin, trypsin inhibitor
49777
91
179
333
PEBP-like
49785
208
788
1354
Galactose-binding domain-like
49818
82
1609
2964
Viral protein domain
49830
39
214
455
F-MuLV receptor-binding domain
49835
38
81
156
Virus attachment protein
49842
80
282
650
TNF-like
49854
29
185
306
Spermadhesin, CUB domain
49863
8
8
38
Hyaluronate lyase-like, C-terminal domain
49870
60
164
477
Osmotin, thaumatin-like protein
49879
71
300
527
SMAD/FHA domain
49889
15
23
60
Soluble secreted chemokine inhibitor, VCCI
49894
6
11
38
Paculovirus p35
49899
370
1443
2261
Concanavalin A-like lectins/glucanases
49994
28
38
150
beta-Galactosidase, domain 5
49998
28
67
202
Copper amine oxidase, domain 3 (catalytic)
50005
17
26
102
Hyaluronate lyase-like, central domain
50012
5
6
29
EV matrix protein
50017
3
5
20
gp9
50022
193
526
886
ISP domain
50037
33
49
95
C-terminal domain of transcriptional repressors
50044
89
795
2052
SH3-domain
50084
48
132
409
Myosin S1 fragment, N-terminal domain
50090
53
89
108
Electron transport accessory proteins
50104
235
694
934
Translation proteins SH3-like domain
50118
10
13
44
Cell growth inhibitor/plasmid maintainance toxic component
50122
43
324
1133
DNA-binding domain of retroviral integrase
50129
372
1035
1630
GroES-like
50151
28
52
99
SacY-like RNA-binding domain
50156
121
643
1638
PDZ domain-like
50176
15
17
217
N-terminal domains of the minor coat protein g3p
50182
56
266
492
Sm-like ribonucleoproteins
50193
180
221
442
Ribosomal protein L14
50199
69
154
239
Staphylococcal nuclease
50203
58
208
475
Bacterial enterotoxins
50242
26
81
210
TIMP-like
50249
478
3109
3708
Nucleic acid-binding proteins
50324
113
180
328
Inorganic pyrophosphatase
50331
100
355
467
MOP-like
50341
71
253
402
CheW-like
50346
20
35
67
Photosynthetic reaction centre, H-chain, cytoplasmic domain
50353
81
319
689
Cytokine
50370
63
223
391
Ricin B-like lectins
50382
3
4
24
Agglutinin
50386
87
225
373
STI-like
50405
39
83
184
Actin-crosslinking proteins
50443
7
8
29
L-fucose isomerase, C-terminal domain
50447
1676
2187
3721
Translation proteins
50465
1302
1501
2403
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
50475
120
325
410
FMN-binding split barrel
50486
122
206
298
FMT C-terminal domain-like
50494
377
2451
4632
Trypsin-like serine proteases
50610
4
4
15
mu transposase, C-terminal domain
50615
1324
1705
2442
N-terminal domain of alpha and beta subunits of F1 ATP synthase
50621
158
357
516
Alanine racemase-like, C-terminal domain
50630
136
581
1119
Acid proteases
50677
137
348
699
ValRS/IleRS/LeuRS editing domain
50685
38
72
146
Barwin-like endoglucanases
50692
128
349
671
ADC-like
50715
111
172
275
Ribosomal protein L25-like
50723
6
10
44
Core binding factor beta, CBF
50729
87
911
1928
PH domain-like
50784
14
33
76
Transcription factor IIA (TFIIA), N-terminal domain
50789
43
60
164
Herpes virus serine proteinase, assemblin
50800
166
307
527
PK beta-barrel domain-like
50809
5
7
37
XRCC4, N-terminal domain
50814
160
608
1132
Lipocalins
50876
13
33
103
Avidin/streptavidin
50882
11
17
35
Metalloprotease inhibitor
50886
6
7
20
D-aminopeptidase, middle and C-terminal domains
50891
183
540
1101
Cyclophilin (peptidylprolyl isomerase)
50904
5
18
32
Oncogene products
50911
24
50
112
Mannose 6-phosphate receptor domain
50916
16
24
61
Rap30/74 interaction domains
50923
46
199
496
Hemopexin-like domain
50934
1
2
15
Tachylectin-2
50939
99
684
1461
Sialidases (neuraminidases)
50952
56
212
274
Soluble quinoprotein glucose dehydrogenase
50956
12
18
55
Thermostable phytase (3-phytase)
50960
93
261
362
TolB, C-terminal domain
50965
29
179
269
Galactose oxidase, central domain
50969
65
272
453
YVTN repeat-like/Quinoprotein amine dehydrogenase
50974
21
64
189
Nitrous oxide reductase, N-terminal domain
50978
82
428
912
WD40-repeat
50985
42
189
317
RCC1/BLIP-II
50989
15
20
65
Clathrin heavy-chain terminal domain
50993
60
230
304
Prolyl oligopeptidase, N-terminal domain
50998
71
280
559
Quinoprotein alcohol dehydrogenase-like
51004
80
271
443
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
51011
255
541
1030
alpha-Amylases, C-terminal beta-sheet domain
51045
31
207
658
WW domain
51055
53
98
146
Carbohydrate binding domain
51064
128
156
256
Head domain of nucleotide exchange factor GrpE
51069
67
231
607
Carbonic anhydrase
51081
9
33
78
Bacteriochlorophyll A protein
51087
33
158
405
Outer surface protein A
51092
5
20
36
Vitelline membrane outer protein-I (VMO-I)
51096
13
110
306
delta-Endotoxin (insectocide), middle domain
51101
27
129
239
Mannose-binding lectins
51110
65
210
279
alpha-D-mannose-specific plant lectins
51120
58
221
312
Serralysin-like metalloprotease, C-terminal domain
51126
236
975
1311
Pectin lyase-like
51156
18
40
85
Insect cysteine-rich antifreeze protein
51161
162
555
923
Trimeric LpxA-like enzymes
51177
2
12
29
An insect antifreeze protein
51182
241
638
840
RmlC-like cupins
51197
129
371
639
Clavaminate synthase-like
51206
145
359
638
cAMP-binding domain-like
51215
8
9
26
Regulatory protein AraC
51219
6
6
12
Trp RNA-binding attenuation protein (TRAP)
51225
31
68
119
Fibre shaft of virus attachment proteins
51230
195
745
1555
Single hybrid motif
51246
204
593
927
Rudiment single hybrid motif
51261
63
147
323
Duplicated hybrid motif
51269
10
66
115
Type III antifreeze protein
51274
7
10
23
Head decoration protein D (gpD, major capsid protein D)
51278
77
107
299
Urease, beta-subunit
51283
143
249
511
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
51289
14
16
36
ACMNPV telokin-like protein
51294
96
220
307
Hedgehog/intein (Hint) domain
51306
158
459
644
LexA/Signal peptidase
51316
40
76
142
Mss4-like
51322
8
11
25
Cyanovirin-N
51327
10
10
18
Head-binding domain of phage P22 tailspike protein
51332
112
130
298
E2 regulatory, transactivation domain
51338
113
246
493
Composite domain of metallo-dependent hydrolases
51344
251
277
398
Epsilon subunit of F1F0-ATP synthase N-terminal domain
51351
203
375
713
Triosephosphate isomerase (TIM)
51366
262
1321
2078
Ribulose-phoshate binding barrel
51391
117
269
358
Thiamin phosphate synthase
51395
197
808
1171
FMN-linked oxidoreductases
51412
139
321
570
Inosine monophosphate dehydrogenase (IMPDH)
51419
178
468
774
PLP-binding barrel
51430
187
690
1342
NAD(P)-linked oxidoreductase
51445
549
1930
3217
(Trans)glycosidases
51556
184
685
919
Metallo-dependent hydrolases
51569
309
1651
2437
Aldolase
51604
249
551
1165
Enolase C-terminal domain-like
51621
213
479
739
Phosphoenolpyruvate/pyruvate domain
51645
77
90
185
Malate synthase G
51649
6873
7595
9207
RuBisCo, C-terminal domain
51658
147
349
555
Xylose isomerase-like
51679
108
326
453
Bacterial luciferase-like
51690
113
218
371
Quinolinic acid phosphoribosyltransferase, C-terminal domain
51695
57
202
476
Phosphatidylinositol-specific phospholipase C (PI-PLC)
51703
58
108
285
Cobalamin (vitamin B12)-dependent enzymes
51713
107
137
277
tRNA-guanine transglycosylase
51717
141
293
534
Dihydropteroate synthetase-like
51726
125
244
396
Uroporphyrinogen decarboxylase, UROD
51730
99
127
235
FAD-linked oxidoreductase
51735
906
5360
8213
NAD(P)-binding Rossmann-fold domains
51971
239
958
1349
Nucleotide-binding domain
51984
114
221
286
MurCD N-terminal domain
51989
39
60
157
Cellulases
51998
180
332
531
PFL-like glycyl radical enzymes
52009
139
252
467
Phosphohistidine domain
52016
117
214
346
Aconitase
52021
141
184
417
Carbamoyl phosphate synthetase, small subunit N-terminal domain
52025
48
140
234
Transferrin receptor ectodomain, apical domain
52029
408
738
1438
GroEL apical domain-like
52038
21
29
50
Barstar (barnase inhibitor)
52042
49
78
117
Ribosomal protein L32e
52047
41
310
469
RNI-like
52058
167
911
1337
L domain-like
52075
43
235
305
Outer arm dynein light chain 1
52080
164
297
383
Ribosomal proteins L15p and L18e
52087
26
182
290
C-terminal domain of phosphatidylinositol transfer protein sec14p
52091
87
250
299
Anti-sigma factor antagonist SpoIIaa
52096
310
906
1381
ClpP/crotonase
52113
125
243
382
BRCT domain
52121
195
305
624
Lumazine synthase
52129
45
225
451
Caspase-like
52141
174
294
496
DNA glycosylase
52151
127
317
600
FabD/lysophospholipase-like
52156
131
163
271
Initiation factor IF2/eIF5b, domain 3
52161
140
179
254
Ribosomal protein L13
52166
146
205
335
Ribosomal protein L4
52172
328
3715
5432
CheY-like
52200
28
199
325
Toll/Interleukin receptor TIR domain
52206
4
4
10
Hypothetical protein MTH538
52210
112
338
689
Succinyl-CoA synthetase domains
52218
196
615
1012
Flavoproteins
52242
108
261
504
Cobalamin (vitamin B12)-binding domain
52251
8
12
25
Ornithine decarboxylase N-terminal "wing" domain
52255
118
161
317
N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) mutase PurE
52259
29
59
142
Cutinase-like
52266
119
338
497
Esterase/acetylhydrolase
52279
94
180
239
Beta-D-glucan exohydrolase, C-terminal domain
52283
197
619
933
Formate/glycerate dehydrogenase catalytic domain-like
52304
68
83
187
Type II 3-dehydroquinate dehydratase
52309
30
39
47
Nucleoside 2-deoxyribosyltransferase
52313
231
258
510
Ribosomal protein S2
52317
192
898
1587
Class I glutamine amidotransferase-like
52335
124
281
562
Methylglyoxal synthase-like
52343
287
773
1549
Ferredoxin reductase-like, C-terminal NADP-linked domain
52374
181
1411
2594
Nucleotidylyl transferase
52402
171
623
1035
Adenine nucleotide alpha hydrolases-like
52413
23
39
105
UDP-glucose dehydrogenase (UDPGDH), C-terminal (UDP-binding) domain
52418
115
203
294
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
52425
97
168
301
Cryptochrome/photolyase, N-terminal domain
52431
137
563
832
ETFP adenine nucleotide-binding domain-like
52440
216
812
1589
PreATP-grasp domain
52467
217
775
1391
DHS-like NAD/FAD-binding domain
52490
534
1087
1910
Tubulin, GTPase domain
52499
105
269
365
Cysteine hydrolase
52507
118
238
392
DFP DNA/pantothenate metabolism flavoprotein
52512
98
223
315
Phosphosugar isomerase
52518
262
1201
1857
Thiamin diphosphate-binding fold (THDP-binding)
52540
2158
10101
14975
P-loop containing nucleotide triphosphate hydrolases
52728
32
73
155
Fructose permease, subunit IIb
52733
68
76
139
Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
52738
60
134
270
Methylesterase CheB, C-terminal domain
52743
165
449
859
Subtilisin-like
52768
128
390
569
Arginase/deacetylase
52777
147
353
750
CoA-dependent acyltransferases
52788
100
216
399
Phosphotyrosine protein phosphatases I
52794
33
78
148
Enzyme IIB-cellobiose
52799
88
642
1704
(Phosphotyrosine protein) phosphatases II
52821
131
457
723
Rhodanese/Cell cycle control phosphatase
52833
440
2719
3926
Thioredoxin-like
52913
5
6
28
RNA 3'-terminal phosphate cyclase, RPTC, insert domain
52922
163
412
636
TK C-terminal domain-like
52935
142
228
483
Pyruvate kinase, C-terminal domain
52943
143
219
414
ATP syntase (F1-ATPase), gamma subunit
52949
68
90
144
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain
52954
134
400
804
Anticodon-binding domain of Class II aaRS
52964
36
40
72
TolB, N-terminal domain
52968
11
13
40
B12-dependend dehydatases associated subunit
52972
113
248
425
Maf/Ham1
53032
31
44
82
tRNA splicing endonuclease, C-terminal domain
53036
14
25
49
Eukaryotic RPB5 N-terminal domain
53041
169
261
495
Resolvase-like
53056
104
192
358
beta-carbonic anhydrase, cab
53062
58
139
214
IIA domain of mannose transporter, IIA-Man
53067
570
1696
3154
Actin-like ATPase domain
53092
127
272
358
Creatinase/prolidase N-terminal domain
53098
227
511
744
Ribonuclease H-like
53137
214
494
762
Translational machinery components
53146
57
143
168
MTH1175-like
53150
90
105
216
DNA repair protein MutS, domain II
53155
34
37
72
Methylated DNA-protein cysteine methyltransferase domain
53163
65
106
150
HybD-like
53167
122
302
630
Purine and uridine phosphorylases
53178
97
112
255
Peptidyl-tRNA hydrolase
53182
39
56
136
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
53187
172
796
1283
Zn-dependent exopeptidases
53213
82
136
160
LigB subunit of an aromatic-ring-opening dioxygenase LigAB
53218
106
310
529
Molybdenum cofactor biosynthesis proteins
53223
207
436
918
Aminoacid dehydrogenase-like, N-terminal domain
53244
106
457
752
MurD-like peptide ligases, peptide-binding domain
53254
139
439
905
Phosphoglycerate mutase-like
53271
232
894
1510
PRTase-like
53300
205
383
1030
vWA-like
53316
89
311
379
CoA transferase
53323
82
193
278
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
53328
122
308
638
Formyltransferase
53335
319
1812
2983
S-adenosyl-L-methionine-dependent methyltransferases
53383
645
3259
5916
PLP-dependent transferases
53448
242
1207
1990
Nucleotide-diphospho-sugar transferases
53474
453
2333
4107
alpha/beta-Hydrolases
53590
58
109
233
Nucleoside hydrolase
53597
170
348
737
Dihydrofolate reductases
53613
136
566
763
Ribokinase-like
53623
117
479
881
MurD-like peptide ligases, catalytic domain
53633
113
225
345
Carbamate kinase-like
53639
97
203
368
AraD-like aldolase/epimerase
53644
19
40
79
Cytosolic phospholipase A2 catalytic
53649
156
515
808
Alkaline phosphatase-like
53659
171
395
806
Isocitrate/Isopropylmalate dehydrogenases
53671
185
364
737
Aspartate/ornithine carbamoyltransferase
53681
102
184
307
Aspartate/glutamate racemase
53686
186
671
1320
Tryptophan synthase beta subunit-like PLP-dependent enzymes
53697
227
596
997
SIS domain
53706
99
295
630
Formate dehydrogenase/DMSO reductase, domains 1-3
53720
253
1178
1967
ALDH-like
53732
112
235
326
Aconitase iron-sulfur domain
53738
147
376
813
Phosphoglucomutase, first 3 domains
53743
17
19
40
L-fucose isomerase, N-terminal and second domains
53748
177
277
553
Phosphoglycerate kinase
53756
134
574
790
UDP-Glycosyltransferase/glycogen phosphorylase
53774
88
126
225
Glutaminase/Asparaginase
53784
122
211
392
Phosphofructokinase
53790
117
253
427
Cobalt precorrin-4 methyltransferase CbiF
53795
222
309
595
PEP carboxykinase-like
53800
114
193
365
Chelatase
53807
219
789
1189
"Helical backbone" metal receptor
53822
153
937
1789
Periplasmic binding protein-like I
53850
264
1518
2395
Periplasmic binding protein-like II
53901
415
1441
2717
Thiolase-like
53920
42
75
164
Fe-only hydrogenase
53927
71
102
147
Cytidine deaminase-like
53933
58
122
304
Microbial ribonucleases
53955
315
1013
1660
Lysozyme-like
54001
237
816
1597
Cysteine proteinases
54060
69
148
233
His-Me finger endonucleases
54076
121
354
749
RNase A-like
54098
96
124
370
Prion-like
54106
96
214
267
LysM domain
54111
77
100
249
Urease, gamma-subunit
54117
53
293
664
Interleukin 8-like chemokines
54160
48
197
339
Chromo domain-like
54171
41
290
564
DNA-binding domain
54184
49
87
193
Penicillin-binding protein 2x (pbp-2x), c-terminal domain
54189
166
326
421
Ribosomal proteins L23 and L15e
54197
140
299
426
HIT-like
54211
573
1842
2789
Ribosomal protein S5 domain 2-like
54236
176
743
1408
Ubiquitin-like
54277
14
39
107
CAD & PB1 domains
54285
96
183
236
MoaD/ThiS
54292
339
982
1559
2Fe-2S ferredoxin-like
54328
24
60
122
Staphylokinase/streptokinase
54334
40
153
386
Superantigen toxins, C-terminal domain
54358
20
44
88
Immunoglobulin-binding domains
54364
94
119
265
Translation initiation factor IF3, N-terminal domain
54368
180
245
453
Glutamine synthetase, N-terminal domain
54373
178
525
842
FAD-linked reductases, C-terminal domain
54403
93
269
484
Cystatin/monellin
54416
34
66
156
Copper amine oxidase, domains 1 and 2
54423
17
19
35
Disulfide bond isomerase, DsbC, N-terminal domain
54427
137
459
644
NTF2-like
54441
4
4
21
Uracil-DNA glycosylase inhibitor protein
54447
11
18
36
ssDNA-binding transcriptional regulator domain
54452
186
2391
4185
MHC antigen-recognition domain
54495
74
427
957
UBC-like
54506
98
215
328
Diaminopimelate epimerase
54511
38
126
412
GFP-like
54518
13
45
125
Transcriptional factor tubby, C-terminal domain
54523
93
407
648
Pilin
54529
20
35
71
Acidic mitochondrial matrix protein p32
54534
216
689
1050
FKBP-like
54552
6
12
23
Colicin E3 immunity protein
54556
170
308
620
Chitinase insertion domain
54565
114
126
270
Ribosomal protein S16
54570
176
224
441
Ribosomal protein S19
54575
45
106
133
Ribosomal protein L31e
54580
17
22
40
Allophycocyanin linker chain (domain)
54585
54
93
197
Cdc48 domain 2-like
54593
183
529
817
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
54611
37
42
86
Bacterial protein-export protein SecB
54616
11
17
34
DNA-binding domain of Mlu1-box binding protein MBP1
54621
10
10
27
Heme-binding protein A (HasA)
54626
33
46
98
Chalcone isomerase
54631
119
285
453
CBS-domain
54637
142
447
556
Thioesterase/thiol ester dehydrase-isomerase
54648
19
47
104
Dynein light chain 8 (DLC8)
54654
41
119
184
CI-2 family of serine protease inhibitors
54665
114
231
525
CO dehydrogenase molybdoprotein N-domain-like
54675
89
122
229
Quinolinic acid phosphoribosyltransferase, N-terminal domain
54680
50
56
106
Pyrimidine nucleoside phosphorylase C-terminal domain
54686
179
228
328
Ribosomal protein L10e
54690
77
89
160
Molybdopterin synthase subunit MoaE
54695
76
478
967
POZ domain
54713
115
142
301
Elongation factor Ts (EF-Ts), dimerisation domain
54719
338
494
1120
Fe,Mn superoxide dismutase (SOD), C-terminal domain
54736
134
183
376
ClpS-like
54742
14
30
61
Transcription-state regulator AbrB, the N-terminal DNA recognition domain
54747
138
160
316
Ribosomal protein L11, N-terminal domain
54752
180
221
467
RecA protein, C-terminal domain
54762
14
29
60
Signal recognition particle alu RNA binding heterodimer, SRP9/14
54768
174
428
693
dsRNA-binding domain-like
54782
98
111
233
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
54786
6
6
13
PI-Pfui intein middle domain
54791
101
331
756
Eukaryotic type KH-domain (eKH-domain)
54806
11
17
24
Alpha-lytic protease prodomain
54810
107
120
265
GMP synthetase C-terminal dimerisation domain
54814
210
436
718
Prokaryotic type KH domain (pKH-domain)
54821
202
234
434
Ribosomal protein S3 C-terminal domain
54826
281
620
1202
Enolase N-terminal domain-like
54843
165
268
465
Ribosomal protein L22
54849
473
775
1496
GroEL-intermediate domain like
54857
15
29
54
DNA damage-inducible protein DinI
54862
260
1071
1316
4Fe-4S ferredoxins
54893
33
37
95
Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
54897
110
325
512
Protease propeptides/inhibitors
54909
10
12
19
Dimeric alpha+beta barrel
54913
94
184
395
GlnB-like
54919
143
223
507
Nucleoside diphosphate kinases
54928
170
1617
3519
RNA-binding domain, RBD
54957
115
164
313
Viral DNA-binding domain
54966
6834
7260
8995
RuBisCO, large subunit, small (N-terminal) domain
54975
97
156
190
Acylphosphatase-like
54980
208
302
580
EF-G/eEF-2 domains III and V
54984
58
95
228
eEF-1beta-like
54991
100
117
186
Anticodon-binding domain of PheRS
54995
99
111
154
Ribosomal protein S6
54999
146
184
343
Ribosomal protein S10
55003
17
36
91
Poly(A) polymerase, C-terminal domain
55008
210
471
903
Metal-binding domain
55021
153
439
565
Regulatory domain in the aminoacid metabolism
55031
95
236
268
Bacterial exopeptidase dimerisation domain
55035
114
150
320
NAD-binding domain of HMG-CoA reductase
55040
93
103
227
Molybdenum cofactor biosynthesis protein C, MoaC
55044
8
10
26
TRADD, N-terminal domain
55048
110
222
313
Probable ACP-binding domain of malonyl-CoA ACP transacylase
55052
8
11
28
CheY-binding domain of CheA
55056
4
4
14
Killer toxin KP6 alpha-subunit
55060
130
277
375
GHMP Kinase
55064
8
9
16
Translational regulator protein regA
55068
109
183
393
Peptide methionine sulfoxide reductase
55073
64
304
709
Adenylyl and guanylyl cyclase catalytic domain
55083
84
110
221
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
55088
20
70
190
Methyl-coenzyme M reductase subunits
55103
94
263
398
FAD-linked oxidases, C-terminal domain
55112
18
24
64
Formylmethanofuran:tetrahydromethanopterin formyltransferase
55116
18
24
51
Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55120
135
313
438
Pseudouridine synthase
55124
114
190
247
Sulfite reductase, domains 1 and 3
55129
110
202
237
Ribosomal protein L30p/L7e
55136
46
102
119
Probable bacterial effector-binding domain
55144
4
5
22
tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase
55149
8
9
29
Pepsin inhibitor-3
55154
5
7
25
mRNA triphosphatase CET1
55159
71
129
237
eIF1-like
55166
68
102
188
Hedgehog/DD-pepidase
55174
769
869
1328
Alpha-L RNA-binding motif
55186
115
216
406
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
55190
112
130
161
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
55194
103
128
294
Ribosome recycling factor, RRF
55200
102
114
293
Translation initiation factor IF3, C-terminal domain
55205
158
339
658
EPT/RTPC-like
55216
10
11
23
C-terminal domain of TolA
55221
5
7
16
Yest killer toxins
55229
23
26
47
Cell division protein MinE topological specificity domain
55234
22
27
52
Cyanase C-terminal domain
55239
205
338
809
RuBisCO, small subunit
55248
57
69
130
Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
55252
42
55
119
C-terminal domain of arginine repressor
55257
185
274
372
RBP11-like subunits of RNA polymerase
55261
111
131
261
Prokaryotic AspRS, insert domain
55267
13
13
20
tRNA splicing endonuclease EdnA, N-terminal domain
55271
108
144
328
DNA repair protein MutS, domain I
55277
5
6
21
GYF domain
55282
173
218
428
Ribosomal protein L5
55287
44
84
139
RPB5-like RNA polymerase subunit
55298
109
266
463
YjgF-like
55307
519
1078
2131
Tubulin, C-terminal domain
55315
102
413
622
L30e-like
55326
112
216
395
Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain
55331
88
164
259
Tautomerase/MIF
55347
138
442
624
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
55383
8
38
58
Copper amine oxidase, domain N
55387
33
43
97
Frataxin-like
55394
18
62
129
Bactericidal permeability-increasing protein, BPI
55399
33
37
75
Subtilisin inhibitor
55405
25
38
100
RNA bacteriophage capsid protein
55418
33
82
186
Translation initiation factor eIF4e
55424
240
594
1209
FAD/NAD-linked reductases, dimerisation (C-terminal) domain
55447
72
165
306
CO dehydrogenase flavoprotein C-terminal domain-like
55455
142
570
1033
SRF-like
55464
128
167
472
Origin of replication-binding domain, RBD-like
55469
105
320
602
NADH oxidase/flavin reductase
55481
54
66
152
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
55486
156
675
1305
Metalloproteases ("zincins"), catalytic domain
55545
53
90
141
beta-N-acetylhexosaminidase-like domain
55550
82
612
1651
SH2 domain
55594
99
169
346
HPr-like
55604
69
201
353
Glucose permease domain IIB
55608
164
333
430
Homing endonucleases
55620
166
471
726
Tetrahydrobiopterin biosynthesis enzymes-like
55637
15
26
58
Cell cycle regulatory proteins
55648
5
7
18
beta-lactamase-inhibitor protein, BLIP
55653
93
100
187
Ribosomal protein L9 C-domain
55658
109
135
199
L9 N-domain-like
55666
110
134
264
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
55671
31
1765
3280
Regulatory factor Nef
55676
8
18
50
Mosquitocidal delta-endotoxin CytB
55681
172
1336
2479
Class II aaRS and biotin synthetases
55711
10
32
115
Clathrin adaptor appendage domain
55718
64
120
225
Sterol carrier protein, SCP
55724
11
15
31
Ran-binding protein mog1p
55729
163
638
985
Acyl-CoA N-acyltransferases (Nat)
55753
71
278
550
Actin depolymerizing proteins
55770
78
151
303
Profilin (actin-binding protein)
55781
99
223
306
GAF domain-like
55785
101
463
658
PYP-like sensor domain (PAS domain)
55797
95
289
499
PR-1-like
55804
101
325
562
Phoshotransferase/anion transport protein
55811
137
501
653
Nudix
55816
77
159
221
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
55821
136
337
500
YrdC/RibB
55826
87
187
260
Hypothetical protein HI1434 (YbaK homologue)
55831
159
235
535
Thymidylate synthase/dCMP hydroxymethylase
55846
97
193
232
N-acetylmuramoyl-L-alanine amidase-like
55856
125
272
579
Cytochrome b5
55869
20
23
49
DNA topoisomerase I domain
55874
431
1443
2507
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
55890
9
9
28
Sporulation responce regulatory protein Spo0B
55895
98
359
637
Ribonuclease Rh-like
55904
49
74
118
Ornithine decarboxylase C-terminal domain
55909
125
211
342
Pentein
55920
138
366
807
Creatinase/aminopeptidase
55931
226
385
845
Glutamine synthase/guanido kinase
55945
105
168
374
TATA-box binding protein-like
55957
50
69
196
Phosphoglucomutase, C-terminal domain
55961
189
644
971
Bet v1-like
55973
138
204
447
S-adenosylmethionine synthetase
55979
207
323
519
DNA clamp
56003
109
242
518
Molybdemum cofactor-binding domain
56014
179
286
368
Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
56019
13
27
72
The spindle assembly checkpoint protein mad2
56024
136
337
443
Phospholipase D/nuclease
56029
44
57
92
Monooxygenase (hydroxylase) regulatory protein
56037
123
163
279
B3/B4 domain of PheRS, PheT
56042
110
130
287
Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain
56047
185
239
463
Ribosomal protein S8
56053
166
234
404
Ribosomal protein L6
56059
277
1265
2578
Glutathione synthetase ATP-binding domain-like
56091
184
344
562
DNA ligase/mRNA capping enzyme, catalytic domain
56104
117
225
360
SAICAR synthase-like
56112
541
6467
13407
Protein kinase-like (PK-like)
56176
171
561
842
FAD-binding domain
56194
85
97
214
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
56199
23
24
67
Methenyltetrahydromethanopterin cyclohydrolase
56204
21
167
425
Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap)
56209
20
24
49
Nitrile hydratase alpha chain
56214
122
196
311
4'-phosphopantetheinyl transferase
56219
124
374
745
DNase I-like
56228
21
50
110
Aldehyde ferredoxin oxidoreductase, N-terminal domain
56235
216
867
1424
N-terminal nucleophile aminohydrolases (Ntn hydrolases)
56266
27
36
67
L-aminopeptidase D-Ala-esterase/amidase
56271
4
6
7
Histidine decarboxylase
56276
49
77
171
S-adenosylmethionine decarboxylase
56281
163
697
977
Metallo-hydrolase/oxidoreductase
56295
56
210
331
Protein serine/threonine phosphatase 2
56300
86
390
827
Metallo-dependent phosphatases
56317
115
259
480
Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase
56322
142
313
619
ADC synthase
56327
263
534
1317
Lactate & malate dehydrogenases, C-terminal domain
56349
205
437
744
DNA breaking-rejoining enzymes
56366
17
79
240
SMAD MH1 domain
56371
73
225
547
Ribosome inactivating proteins (RIP)
56399
33
111
283
ADP-ribosylation
56420
102
157
314
Peptide deformylase
56425
188
317
617
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
56436
160
863
2031
C-type lectin-like
56487
26
123
342
Scavenger receptor cysteine-rich (SRCR) domain
56491
19
30
111
A heparin-binding domain
56496
41
218
583
Fibrinogen C-terminal domain-like
56502
57
9537
11774
gp120 core
56507
58
65
135
Methionine synthase activation domain-like
56512
33
77
255
Nitric oxide (NO) synthase oxygenase domain
56519
86
185
303
Penicillin binding protein dimerisation domain
56524
105
181
278
Sulfite oxidase, middle catalytic domain
56529
103
289
517
FAH
56534
42
77
198
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
56542
109
162
303
Substrate-binding domain of HMG-CoA reductase
56548
21
27
55
Conserved core of transcriptional regulatory protein vp16
56553
188
222
374
Insert subdomain of RNA polymerase alpha subunit
56558
6
6
14
Baseplate structural protein gp11
56563
57
97
133
Major capsid protein gp5
56568
11
22
41
Non-globular alpha+beta subunits of globular proteins
56574
114
564
1021
Serpins
56596
9
12
24
Replication terminator protein (Tus)
56601
233
1083
2121
beta-Lactamase/D-ala carboxypeptidase
56629
8
13
46
ADP ribosyl cyclase-like
56634
129
240
295
Heme-linked catalases
56645
89
504
913
Acyl-CoA dehydrogenase NM domain-like
56655
155
437
832
Sugar phosphatases
56712
127
244
512
Prokaryotic type I DNA topoisomerase
56719
180
324
792
Type II DNA topoisomerase
56726
27
34
76
DNA topoisomerase IV, alpha subunit
56731
117
173
320
DNA primase DnaG catalytic core
56736
82
114
241
DNA repair protein MutM (Fpg)
56741
27
36
120
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
56747
32
38
58
DNA primase
56752
112
239
517
D-aminoacid aminotransferase-like PLP-dependent enzymes
56762
143
257
408
Nickel-iron hydrogenase, large subunit
56770
134
227
330
Nickel-iron hydrogenase, small subunit
56778
394
771
1416
Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
56784
190
784
1016
HAD-like
56796
132
311
498
Dehydroquinate synthase-like
56801
201
813
1278
Firefly luciferase-like
56808
152
221
401
Ribosomal protein L1
56815
24
100
158
Sec1/munc18-like (SM) proteins
56821
37
74
155
Prismane protein-like
56826
9
10
30
Upper collar protein gp10 (connector protein)
56831
15
40
88
BTV inner layer core protein vp3
56837
25
51
135
Colicin
56845
4
10
44
Diphtheria toxin, middle domain
56849
25
150
401
delta-Endotoxin (insectocide), N-terminal domain
56854
39
165
316
Bcl-2 inhibitors of programmed cell death
56864
3
4
18
Exotoxin A, middle domain
56918
35
102
155
Light-harvesting complex subunits
56925
174
396
574
OMPA-like
56931
19
25
46
Outer membrane phospholipase A (OMPLA)
56935
92
718
988
Porins
56954
70
239
302
Integral outer membrane protein TolC, efflux pump component
56959
17
56
170
Leukocidin (pore-forming toxin)
56973
9
30
88
(Pro)aerolysin, pore-forming lobe
56978
25
47
150
Perfringolysin
56983
48
374
1006
Viral glycoprotein, central and dimerisation domains
56988
5
7
72
Anthrax protective antigen
56994
90
166
259
Insulin-like
57007
3
3
8
Heat-stable enterotoxin B
57011
5
8
10
Neurotoxin B-IV
57016
82
177
381
Plant lectins/antimicrobial peptides
57027
24
43
57
Plant inhibitors of proteinases and amylases
57038
10
26
38
Cyclotides
57048
8
11
26
Gurmarin-like
57055
9
14
34
Agouti-related protein
57059
27
63
91
omega toxin-like
57095
91
325
464
Scorpion toxin-like
57180
46
106
203
Cellulose-binding domain
57184
40
206
359
Growth factor receptor domain
57190
16
33
81
Colipase-like
57196
152
1066
1854
EGF/Laminin
57243
5
6
6
Bromelain inhibitor VI (cysteine protease inhibitor)
57247
49
125
231
Bowman-Birk inhibitor, BBI
57256
15
35
66
Elafin-like
57262
18
45
76
Leech antihemostatic proteins
57277
4
8
18
Granulin repeat
57283
12
22
45
PMP inhibitors
57288
12
27
61
Midkine
57296
1
1
4
Amb V allergen
57302
95
538
913
Snake toxin-like
57362
96
320
704
BPTI-like
57392
36
76
163
Defensin-like
57414
17
36
90
Hairpin loop containing domain-like
57419
2
2
3
Neurotoxin III (ATX III)
57424
38
241
525
LDL receptor-like module
57429
24
67
134
Crambin-like
57440
67
278
666
Kringle-like
57467
173
371
642
Ovomucoid/PCI-1 like inhibitors
57492
35
82
157
Trefoil
57501
319
945
1890
Cystine-knot cytokines
57535
81
367
908
Complement control module/SCR domain
57546
9
22
31
Sea anemone toxin k
57552
66
242
577
Blood coagulation inhibitor (disintegrin)
57561
9
11
34
Methylamine dehydrogenase, L chain
57567
43
157
237
Serine proterase inhibitors
57581
11
41
106
TB module/8-cys domain
57586
12
18
64
TNF receptor-like
57593
20
34
99
Heparin-binding domain from vascular endothelial growth factor
57598
4
5
12
Antifungal protein (AGAFP)
57603
20
49
147
Fibronectin type I module
57610
28
118
242
Thyroglobulin type-1 domain
57615
11
24
38
Type X cellulose binding domain, CBDX
57620
6
9
17
Carboxypeptidase inhibitor
57625
31
149
201
Tachycitin
57630
8
11
35
GLA-domain
57642
5
7
21
Cholecystokinin A receptor, N-domain
57647
11
570
1050
HIV-1 VPU cytoplasmic domain
57652
23
37
69
HIPIP (high potential iron protein)
57662
22
26
50
Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
57667
404
2347
4331
C2H2 and C2HC zinc fingers
57701
42
173
361
Zn2/Cys6 DNA-binding domain
57716
269
867
1458
Glucocorticoid receptor-like (DNA-binding domain)
57756
96
841
2243
Retrovirus zinc finger-like domains
57770
62
67
147
Methionyl-tRNA synthetase (MetRS), Zn-domain
57774
98
153
369
Microbial and mitochondrial ADK, insert "zinc finger" domain
57783
86
202
324
Zinc beta-ribbon
57798
20
38
98
Casein kinase II beta subunit
57802
98
196
253
Rubredoxin-like
57821
3
3
4
Hypothetical protein MTH1184
57825
31
36
73
Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
57829
67
170
220
Zn-binding ribosomal proteins
57840
87
97
169
Ribosomal protein L36
57845
7
90
227
B-box zinc-binding domain
57850
194
840
1535
RING finger domain, C3HC4
57863
19
138
378
Pyk2-associated protein beta ARF-GAP domain
57868
142
286
410
Metallothionein
57879
6
10
25
Zinc domain conserved in yeast copper-regulated transcription factors
57884
38
50
100
Ada DNA repair protein, N-terminal domain (N-Ada 10)
57889
58
266
682
Cysteine-rich domain
57903
42
364
634
FYVE/PHD zinc finger
57917
26
35
66
Zn-binding domains of ADDBP
57924
53
139
344
Inhibitor of apoptosis (IAP) repeat
57933
15
36
79
TAZ domain
57938
150
196
436
Cysteine-rich domain of the chaperone protein DnaJ.
63380
269
730
1286
Riboflavin synthase domain-like
63393
67
133
192
RBP12 subunit of RNA polymerase II
63411
147
426
790
LuxS/MPP-like metallohydrolase
63418
91
209
358
MurE/MurF N-terminal domain
63433
19
25
54
Fumarylacetoacetate hydrolase, FAH, N-terminal domain
63446
22
137
258
Type I dockerin domain
63451
12
37
90
LEM domain
63491
20
24
55
BAG domain
63501
25
135
364
Frizzled cystein-rich domain
63515
42
223
586
Outer surface protein C (OspC)
63520
39
150
239
PTS-regulatory domain, PRD
63562
4
4
11
RNA polymerase omega subunit
63570
36
97
215
PABC (PABP) domain
63592
15
16
42
Flagellar transcriptional activator FlhD
63600
12
21
71
Telomeric repeat binding factor (TRF) dimerisation domain
63697
5
9
39
Olfactory marker protein
63707
5
11
40
Ganglioside M2 (gm2) activator
63712
31
186
261
Nicotinic receptor ligand binding domain-like
63724
4
8
37
Equinatoxin II (eqtII, tenebrosin C)
63732
14
16
41
Lactobacillus maltose phosphorylase, N-terminal domain
63737
77
203
277
Leukotriene A4 hydrolase N-terminal domain
63748
25
179
320
Tudor/PWWP
63763
10
38
128
SAND domain-like
63817
30
77
101
Sortase
63825
70
314
534
Low density lipoprotein (LDL) receptor YWTD domain
63829
50
202
257
Diisopropylfluorophosphatase (phosphotriesterase, DFP)
63840
11
15
34
Ribonuclease domain of colicin E3
63848
49
55
78
Cell-division inhibitor MinC, C-terminal domain
63862
12
15
50
Thiamin pyrophosphokinase, substrate-binding domain
63867
80
110
141
Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain
63877
3
22
108
Methuselah ectodomain
63882
95
157
313
Molybdenum cofactor biosynthesis protein MoeA, N-terminal and linker domains
63887
66
114
267
P-domain of calnexin/calreticulin
63892
47
56
136
Pyridoxine 5'-phosphate synthase
63965
55
65
125
Precorrin-8x methylmutase
63992
17
18
44
Dipeptide transport protein
63999
44
57
94
Thiamin pyrophosphokinase, catalytic domain
64005
118
190
400
Undecaprenyl diphosphate synthase
64043
4
4
9
Cell-division inhibitor MinC, N-terminal domain
64076
41
55
81
Hypothetical protein MT938 (MTH938)
64153
84
101
141
YjeF N-terminal domain-like
64158
69
81
183
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
64167
66
83
172
SurE-like
64182
102
234
295
DHH phosphoesterases
64197
93
111
186
AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
64210
6
8
16
Head-to-tail joining protein W, gpW
64234
35
42
90
Photosystem I subunit PsaD
64263
97
113
239
Prokaryotic ribosomal protein L17
64268
24
182
310
PX domain
64288
38
45
57
Chorismate lyase
64307
78
151
220
SirA-like
64325
60
127
197
Dimeric C-terminal domain of membrane protein TonB
64356
18
61
112
SNARE-like
64376
46
50
74
YlxR-like
64383
23
25
74
Cell-division protein ZipA, C-terminal domain
64397
61
69
123
Hsp33 domain
64438
4
8
52
Type 1 cytotoxic necrotizing factor, catalytic domain
64449
6
10
28
YopH tyrosine phosphatase N-terminal domain
64465
11
46
80
Outer capsid protein sigma 3
64496
7
9
19
DNA-binding domain of intron endonuclease I-TevI
64501
36
72
145
Ku heterodimer subunits
64518
96
264
500
F41 fragment of flagellin
64546
7
8
19
Satiety factor CART (cocaine and amphetamine regulated transcript)
64571
8
30
60
Cellulose docking domain, dockering
64586
40
43
55
C-terminal domain of ProRS
68906
9
12
26
SAP domain
68912
38
44
99
Rho termination factor, N-terminal domain
68918
4
4
15
Recombination endonuclease VII, C-terminal and dimerization domains
68923
98
129
309
PEP carboxykinase N-terminal domain
68930
2
2
8
Protein-L-isoaspartyl O-methyltransferase, C-terminal domain
68989
7
14
30
Hemolysin expression modulating protein HHA
68993
14
20
68
FAT domain of focal adhesion kinase
69000
22
47
101
Thiol oxidase Erv2p
69008
13
15
20
RecG, N-terminal domain
69012
23
48
128
alpha-ketoacid dehydrogenase kinase, N-terminal domain
69025
7
9
17
Hypothetical protein MTH865
69036
4
9
35
Bcr-Abl oncoprotein oligomerization domain
69047
19
32
50
Hypothetical protein YjbJ
69055
75
80
163
1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
69060
10
18
46
Arp2/3 complex 21 kDa subunit ARPC3
69065
108
157
257
RNase III endonuclease catalytic domain
69070
3
3
7
Anti-sigma factor AsiA
69075
15
20
29
Glutamyl tRNA-reductase dimerization domain
69099
4
5
24
Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
69103
15
22
44
Arp2/3 complex 16 kDa subunit ARPC5
69118
15
17
43
Antioxidant defence protein AhpD
69125
9
22
64
Nuclear receptor coactivator interlocking domain
69131
3
5
11
Quinohemoprotein amine dehydrogenase C chain
69179
40
205
365
Integrin domains
69189
52
79
135
Penicillin-binding protein 5, C-terminal domain
69203
11
55
112
Nucleoplasmin core
69255
4
4
12
Tail-associated lysozyme gp5, N-terminal domain
69279
8
11
48
Phage tail proteins
69287
51
66
106
Urease metallochaperone UreE, N-terminal domain
69298
8
8
29
Quinohemoprotein amine dehydrogenase A chain, domain 3
69304
55
213
260
Tricorn protease N-terminal domain
69318
38
163
331
Integrin alpha N-terminal domain
69322
58
207
269
Tricorn protease N-terminal domain
69336
106
149
299
Alpha subunit of glutamate synthase, C-terminal domain
69340
19
27
69
C-terminal domain of adenylylcyclase associated protein
69349
54
108
173
Phage fibre proteins
69360
25
126
298
Choline binding domain of autolysin C-LytA
69369
7
16
54
Colicin E3 translocation domain
69500
65
77
174
D-Tyr tRNAtyr deacylase
69572
113
213
397
Molybdenum cofactor biosynthesis protein MoeB
69593
18
21
78
Glycerol-3-phosphate (1)-acyltransferase
69618
94
125
150
Uroporphyrinogen III synthase (U3S, HemD)
69635
20
34
78
Type III secretory system chaperone
69645
15
41
98
Arp2/3 complex subunits
69652
6
6
13
DNA-binding C-terminal domain of the transcription factor MotA
69687
32
70
151
Integrin beta tail domain
69695
28
35
73
SRP19
69705
95
111
187
Transcription factor NusA, N-terminal domain
69721
21
23
60
DsrC, the gamma subunit of dissimilatory sulfite reductase
69732
75
236
260
Lrp/AsnC-like transcriptional regulator C-terminal domain
69737
149
415
566
Urease metallochaperone UreE, C-terminal domain
69742
90
110
220
Glutamyl tRNA-reductase catalytic, N-terminal domain
69754
90
111
143
Ribosome binding protein Y (YfiA homologue)
69761
2
2
10
GTP cyclohydrolase I feedback regulatory protein, GFRP
69765
79
87
191
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
69786
48
52
74
YggU-like
69796
55
57
75
Thymidylate synthase-complementing protein Thy1
69819
31
35
74
MTH1598-like
69848
14
30
70
LCCL domain
69864
99
121
165
Argininosuccinate synthetase, C-terminal domain
69898
37
92
172
Golgi alpha-mannosidase II
69903
13
35
70
NSP3 homodimer
69908
7
9
9
Membrane penetration protein mu1
69917
11
22
63
OMPT-like
69922
42
161
586
Head and neck region of the ectodomain of NDV fusion glycoprotein
69959
3
5
10
Serine proteinase inhibitor lekti, domain one
69964
3
4
11
Pheromone ER-23
74650
112
256
408
Galactose mutarotase-like
74653
14
17
32
TolA/TonB C-terminal domain
74731
144
162
313
Ribosomal protein L20
74748
24
167
344
Variable surface antigen VlsE
74778
33
40
95
Aconitase B, N-terminal domain
74784
25
37
70
Testis/brain RNA-binding protein (TB-RBP)
74788
19
79
205
Culin repeat
74800
10
18
60
C-terminal activation domain (CTAD) of HIF-1alpha
74853
57
113
243
Lamin A/C globular tail domain
74863
25
32
75
Thiol:disulfide interchange protein DsbD, N-terminal domain
74877
7
23
71
Major surface antigen p30, SAG1
74914
17
34
71
V-region of surface antigen I/II (SA I/II, PAC)
74924
20
68
183
Cap-Gly domain
74942
64
67
95
YhbC-like, C-terminal domain
74982
91
101
230
Small protein B (SmpB)
75001
7
8
32
Dipeptidyl peptidase I (cathepsin C), exclusion domain
75005
95
209
234
alpha-L-arabinanase
75011
1
2
11
3-carboxy-cis,cis-mucoante lactonizing enzyme
75098
3
11
46
Monomethylamine methyltransferase MtmB
75138
58
86
140
HPr kinase/phoshatase HprK N-terminal domain
75169
19
21
37
YchN-like
75181
10
11
23
Hypothetical protein MTH777 (MT0777)
75217
118
261
310
alpha/beta knot
75304
120
241
298
Amidase signature (AS) enzymes
75347
14
28
49
Rotavirus NSP2 fragment, C-terminal domain
75399
14
45
108
Plakin repeat
75404
6
10
26
VSV matrix protein
75412
8
9
19
Hypothetical protein MTH1880
75420
73
79
132
YhbC-like, N-terminal domain
75445
85
103
187
D-ribose-5-phosphate isomerase (RpiA), lid domain
75471
59
82
149
YhbY-like
75500
18
26
41
Putative transcriptional regulator TM1602, C-terminal domain
75516
50
115
146
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors
75520
32
170
340
Clathrin coat assembly domain
75553
84
137
241
Smc hinge domain
75569
8
8
25
Hypothetical protein MTH1020
75574
13
22
41
Rotavirus NSP2 fragment, N-terminal domain
75604
112
236
285
Archaeosine tRNA-guanine transglycosylase, C-terminal additional domains
75615
2
3
8
Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
75620
101
231
487
Polypeptide chain release factor 2 (RF2)
75625
94
120
269
YebC-like
75632
19
85
236
Culin homology domain
75689
34
40
71
Zinc-binding domain of translation initiation factor 2 beta
75704
12
21
46
Mitotic arrest deficient-like 1, Mad1
75708
25
32
71
Chemotaxis phosphatase CheZ
75712
51
106
192
Rad50 coiled-coil Zn hook
81271
98
139
287
TGS-like
81273
19
24
45
H-NS histone-like proteins
81277
8
13
32
C-terminal domain of octopus hemocyanin
81296
343
1381
2167
E set domains
81301
41
94
239
Nucleotidyltransferase
81382
27
84
106
Skp1 dimerisation domain-like
81383
21
208
268
F-box domain
81585
21
36
149
DNA polymerase beta-like, second domain
81593
13
16
46
Nucleotidyltransferase substrate binding subunit/domain
81601
13
26
72
Protein serine/threonine phosphatase 2C, C-terminal domain
81606
62
216
409
Protein serine/threonine phosphatase 2C, catalytic domain
81624
84
118
287
N-terminal domain of MutM-like DNA repair proteins
81631
18
34
111
Poly(A) polymerase, middle domain
81653
137
346
653
Calcium ATPase, transduction domain A
81660
127
330
581
Calcium ATPase, ATP-binding domain N
81698
9
25
52
FF domain
81710
8
8
21
Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
81730
4
6
17
beta-catenin-interacting protein ICAT
81736
13
43
95
Pollen allergen Phl P 6
81761
52
89
279
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
81767
117
155
344
Pre-protein croslinking domain of SecA
81778
32
90
178
Crustacean CHH/MIH/GIH neurohormone
81783
3
6
15
C-terminal domain of DFF45/ICAD (DFF-C domain)
81790
9
30
71
Myosin phosphatase inhibitor 17kDa protein, CPI-17
81799
100
115
257
Putative methyltransferase TM0872, insert domain
81811
23
52
137
Helical domain of Sec23/24
81822
10
15
41
RuBisCo LSMT C-terminal, substrate-binding domain
81827
74
171
221
Porin chaperone SurA, peptide-binding domain
81832
5
13
32
GEF domain of SopE toxin
81837
12
48
157
BEACH domain
81853
8
9
30
Family 10 polysaccharide lyase
81872
10
13
46
BRCA2 helical domain
81878
6
9
39
BRCA2 tower domain
81886
119
147
311
Helical scaffold and wing domains of SecA
81891
94
149
200
tRNA CCA-adding enzyme, C-terminal domains
81901
66
221
274
Cysteine rich protein B (HcpB)
81923
118
238
367
Double Clp-N motif
81930
5
14
44
Orange carotenoid protein, N-terminal domain
81935
65
90
164
N-terminal domain of bifunctional PutA protein
81982
4
4
6
Antigen MPT63/MPB63 (immunoprotective extracellular protein)
81986
8
8
43
Tp47 lipoprotein, middle and C-terminal domains
81995
15
51
122
beta-sandwich domain of Sec23/24
82004
96
113
134
N-utilization substance G protein NusG, insert domain
82026
10
12
18
Fucose-binding lectin II (PA-IIL)
82046
1
2
15
Viral chemokine binding protein m3
82051
103
234
427
Obg GTP-binding protein N-terminal domain
82057
6
23
71
GW domain
82061
3
5
8
BAH domain
82093
41
48
101
Heme chaperone CcmE
82109
19
39
109
IP3 receptor type 1 binding core, domain 1
82114
93
106
137
Riboflavin kinase
82153
55
119
205
FAS1 domain
82171
78
217
302
Dipeptidyl peptidase IV/CD26, N-terminal domain
82185
39
180
243
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82199
49
358
537
SET domain
82215
10
18
59
C-terminal autoproteolytic domain of nucleoporin nup98
82220
1
1
41
Tp47 lipoprotein, N-terminal domain
82282
82
139
182
Betaine-homocysteine S-methyltransferase
82317
10
10
37
Swiveling domain of the glycerol dehydratase reactivase alpha subunit
82544
36
48
117
Putative glycerate kinase (hypothetical protein TM1585)
82549
40
103
170
DegV-like
82602
5
8
16
Nuclease A inhibitor (NuiA)
82607
78
88
154
YbaB-like
82615
3
4
28
Polo domain
82649
42
50
94
SufE (YhnA)
82653
93
105
139
Probable GTPase Der, C-terminal domain
82657
58
119
175
BolA-like
82671
3
3
19
SEA domain
82679
96
118
160
N-utilization substance G protein NusG, N-terminal domain
82689
84
205
273
Mechanosensitive channel protein MscS (YggB), C-terminal domain
82693
71
356
539
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
82697
57
61
81
PurS subunit of FGAM synthetase
82704
24
39
62
DNA-binding protein Sso10b (AlbA)
82708
7
10
25
R3H domain
82714
66
290
455
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
82754
22
59
129
C-terminal, gelsolin-like domain of Sec23/24
82771
109
159
187
GIY-YIG endonuclease
82784
78
182
247
Ohr/OsmC resistance proteins
82808
8
8
22
Replication modulator SeqA, C-terminal DNA-binding domain
82829
35
41
65
Putative cell cycle protein MesJ, middle and C-terminal domain
82895
33
182
581
TSP-1 type 1 repeat
82910
13
45
264
Apical membrane antigen 1
82919
15
45
118
Zn-finger domain of Sec23/24
82927
27
76
167
Cysteine-rich DNA binding domain, (DM domain)
82931
12
21
54
Tumor suppressor gene product Apc
82936
12
16
32
Apolipoprotein A-II