STIFDB - Transcription Factor Information : Entry Name - C_ABRE_bZIP
Details about the Transcription Factor - C_ABRE_bZIP :
| Transcription Factor Family Name | bZIP |
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| Sub-Family | Nil |
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| Description | One group of transcription factors is defined by a basic leucine zipper (bZIP) motif. This bipartite DNA binding structure consists of a region enriched in basic amino acids (basic region) adjacent to a leucine zipper that is characterized by several leucine residues regularly spaced at seven-amino acid intervals. Whereas the basic region directly contacts the DNA, the leucine zipper mediates homodimerization and heterodimerization of protein monomers through a parallel interaction of the hydrophobic dimerization interfaces of two a-helices, resulting in a coiled-coil structure.The in-dividual base pairs are numbered encompassing the G-box from -4 to +4 (numbering from 5' to 3').The DNA binding specificity of GBF1 is strongly influenced by the nature of the nucleotides (positions -4, -3, +3, and +4) flanking the ACGT core sequence. For example, sequences that carry a TG at positions -4 and -3 and a T or G residue at position +4 are as efficiently bound by GBFl as the palindromic G-box. |
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| Stress Signals | ABA,
DROUGHT
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| Name of Cis-Element | C/ABRE
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| Cis-Element | CGCGTG
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| References | Hyung-in Choi.,et al.,2000. Journal of Biological Chemistry, 275(3): 1723-1730,
Kazuo Shinozaki.,et al.,2000. Current Opinion in Plant Biology, 3:217-223.
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| Related Resources | DATF : bZIP |
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Contact:
Prof. R. Sowdhamini [mini@ncbs.res.in]
Prof. M. Udayakumar
STIFdb Team:
Prof. R. Sowdhamini
Prof. M. Udayakumar
K. Shameer
S. Ambika
Susan Mary Varghese
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