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Apicomplexa

 No of genomes            : 43
 No of superfamilies      : 292

Taxonomy       Phylum Statistics       Domain assignments       Domain architecture
Taxonomy [Help]

superkingdom      Eukaryota
phylum      Apicomplexa
Taxonomy       Phylum Statistics       Domain assignments       Domain architecture
Phylum statistics [Help]
LineageNo of members
   Class       1   
   Order       2   
   Family       5   
   Genus       8   
Taxonomy       Phylum Statistics       Domain assignments       Domain architecture


Domain assignments Download sequence in FASTA format
Taxonomy       Phylum Statistics       Domain assignments       Domain architecture
Structural Domain architecture  [help]


The bars indicate various possible structural domain architectures displayed by the superfamily members. Structural domains were identified in the proteins by running IMPALA/HMM against a database of SCOP superfamily profiles/HMM models. The SCOP superfamily code is provided for each of the structural domains
46458

46565 --- 49493 --- 49493

46565 --- 57938 --- 49493 --- 49493

46609 --- 54719

46785

46934 --- 54713 --- 54713

46966 --- 48340

47027

47095

47113

47240

47336

47413

47413 --- 46689

47413 --- 53822

47473

47661

47794 --- 52540

47857

48113

48168 --- 51998

48173

48208

48329 --- 57184

48340

48371

48439 --- 56300

48445

48452 --- 52540 --- 56112

48592 --- 52029 --- 48592

48592 --- 52029 --- 54849

48592 --- 52029 --- 54849 --- 48592

48592 --- 54849 --- 52029 --- 48592

49354

49482

49723 --- 69848 --- 56487 --- 56487 --- 69848 --- 69848

49777

50104

50182

50193

50249

50249 --- 50249

50324

50370 --- 49785 --- 69848

50447 --- 50465

50447 --- 54980 --- 54211 --- 54980

50475

50615 --- 52540 --- 47917

50630

50729

50891

50965 --- 56300

51161

51206 --- 51206

51206 --- 51206 --- 51206 --- 51206 --- 56112

51206 --- 51206 --- 51206 --- 56112

51230 --- 52777

51351

51395

51412

51419 --- 50621

51569

51621 --- 50800 --- 51621 --- 52935

51658

51658 --- 54593 --- 54593

51717

51735

51735 --- 55347

51735 --- 56327

51971

51971 --- 51971 --- 51971 --- 55424

51971 --- 51971 --- 55424

51971 --- 56425 --- 46977

52021 --- 52317 --- 52440 --- 56059 --- 48108 --- 52440 --- 56059 --- 52335

52096

52113 --- 52540

52172 --- 46894

52218 --- 63380 --- 52343

52283

52283 --- 51735

52304

52317 --- 52402 --- 54810

52317 --- 52440 --- 56059 --- 48108

52335

52374 --- 47323

52440

52440 --- 56059 --- 51246 --- 51230

52467

52467 --- 52283 --- 51735

52490 --- 55307

52512 --- 51735

52518 --- 52922 --- 53323 --- 54862 --- 54862 --- 52218 --- 52343

52540

52540 --- 48019

52540 --- 48283

52540 --- 50331

52540 --- 52540

52743

52821

52833

52833 --- 52833

53041 --- 47807

53067

53067 --- 52121 --- 56778

53098

53167

53187

53223 --- 51735

53271

53271 --- 53271

53300 --- 53300 --- 53300 --- 53300 --- 53300 --- 53300 --- 82895 --- 82895

53300 --- 82895

53300 --- 82895 --- 82895

53300 --- 82895 --- 82895 --- 82895

53335

53383

53448

53474

53597

53597 --- 55831

53613

53671 --- 53671

53697

53732 --- 52016

53738 --- 53738 --- 53738 --- 55957

53748 --- 53748

53822

53850

53901 --- 53901

53901 --- 53901 --- 53901

54001

54160

54197

54236

54236 --- 54236 --- 54236 --- 54236 --- 54236

54292

54292 --- 46548

54292 --- 54862 --- 53706 --- 50692

54373

54427

54452

54495

54570

54637

54736

54826 --- 51604

54862

54966 --- 51649

54984

55083 --- 51717

55129

55159

55194

55287

55307

55347 --- 69055

55418

55469

55481 --- 53137 --- 55315

55620

55666 --- 54791 --- 50249

55729 --- 47370

55729 --- 55729

55753

55770

55831

55874

55874 --- 54211 --- 56719

55920 --- 46785

55945 --- 55945

55973 --- 55973 --- 55973

55979 --- 55979

56019

56047

56053

56053 --- 56053

56059 --- 48108

56059 --- 56059 --- 48108 --- 52440 --- 56059

56091

56112

56112 --- 47473

56112 --- 47473 --- 47473

56235

56235 --- 51395 --- 51395 --- 69336 --- 46548 --- 51971 --- 51971

56235 --- 52402

56276 --- 51419 --- 50621

56300

56420

56634

56655

56741 --- 56349 --- 56349

56752

56778

56801 --- 47336 --- 53901 --- 53901 --- 52151 --- 50129 --- 51735 --- 47336 --- 53901 --- 53901 --- 52151 --- 50129 --- 51735 --- 51735 --- 47336 --- 53901 --- 53901 --- 52151 --- 50129 --- 51735 --- 51735 --- 47336 --- 51735

56808

56815

56935

56959

57196

57196 --- 57196

57440

57467

57467 --- 57467 --- 57467 --- 57467

57716 --- 48508

57716 --- 57716

57774

57850

57850 --- 57903

57863

63380 --- 52343

63393

63411 --- 63411

64356

68923 --- 53795

69047

69349

69349 --- 56295

69765

69848 --- 56487 --- 56487 --- 69848 --- 49899

74748

74778 --- 53732

74877

74877 --- 74877

75520

75520 --- 49447

81606 --- 81606

81653

81653 --- 81660 --- 55073 --- 55073

81811 --- 82754

81923 --- 52540 --- 52540

82051 --- 50447 --- 50465

82051 --- 50447 --- 52156 --- 50447

82051 --- 50447 --- 54980 --- 54211 --- 54980

82649

82754

82895

82910

   46458      Globin-like
   46548      alpha-helical ferredoxin
   46565      Chaperone J-domain
   46609      Fe,Mn superoxide dismutase (SOD), N-terminal domain
   46689      Homeodomain-like
   46785      "Winged helix" DNA-binding domain
   46894      C-terminal effector domain of the bipartite response regulators
   46934      UBA-like
   46966      Spectrin repeat
   46977      Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
   47027      Acyl-CoA binding protein
   47095      HMG-box
   47113      Histone-fold
   47240      Ferritin-like
   47323      Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
   47336      ACP-like
   47370      Bromodomain
   47413      lambda repressor-like DNA-binding domains
   47473      EF-hand
   47661      t-snare proteins
   47794      DNA repair protein Rad51, N-terminal domain
   47807      5' to 3' exonuclease, C-terminal subdomain
   47857      Apolipophorin-III
   47917      C-terminal domain of alpha and beta subunits of F1 ATP synthase
   48019      DNA polymerase III clamp loader subunits, C-terminal domain
   48108      Carbamoyl phosphate synthetase, large subunit connection domain
   48113      Heme-dependent peroxidases
   48168      R1 subunit of ribonucleotide reductase, N-terminal domain
   48173      Cryptochrome/photolyase FAD-binding domain
   48208      Six-hairpin glycosyltransferases
   48283      FIS-like
   48329      RNA polymerase sigma subunit
   48340      Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
   48371      ARM repeat
   48439      Protein prenylyltransferase
   48445      14-3-3 protein
   48452      TPR-like
   48508      Nuclear receptor ligand-binding domain
   48592      GroEL equatorial domain-like chaperone equatorial domain
   49354      PapD-like
   49447      Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
   49482      Aromatic compound dioxygenase
   49493      HSP40/DnaJ peptide-binding domain
   49723      Lipase/lipooxygenase domain (PLAT/LH2 domain)
   49777      PEBP-like
   49785      Galactose-binding domain-like
   49899      Concanavalin A-like lectins/glucanases
   50104      Translation proteins SH3-like domain
   50129      GroES-like
   50182      Sm-like ribonucleoproteins
   50193      Ribosomal protein L14
   50249      Nucleic acid-binding proteins
   50324      Inorganic pyrophosphatase
   50331      MOP-like
   50370      Ricin B-like lectins
   50447      Translation proteins
   50465      EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
   50475      FMN-binding split barrel
   50615      N-terminal domain of alpha and beta subunits of F1 ATP synthase
   50621      Alanine racemase-like, C-terminal domain
   50630      Acid proteases
   50692      ADC-like
   50729      PH domain-like
   50800      PK beta-barrel domain-like
   50891      Cyclophilin (peptidylprolyl isomerase)
   50965      Galactose oxidase, central domain
   51161      Trimeric LpxA-like enzymes
   51206      cAMP-binding domain-like
   51230      Single hybrid motif
   51246      Rudiment single hybrid motif
   51351      Triosephosphate isomerase (TIM)
   51395      FMN-linked oxidoreductases
   51412      Inosine monophosphate dehydrogenase (IMPDH)
   51419      PLP-binding barrel
   51569      Aldolase
   51604      Enolase C-terminal domain-like
   51621      Phosphoenolpyruvate/pyruvate domain
   51649      RuBisCo, C-terminal domain
   51658      Xylose isomerase-like
   51717      Dihydropteroate synthetase-like
   51735      NAD(P)-binding Rossmann-fold domains
   51971      Nucleotide-binding domain
   51998      PFL-like glycyl radical enzymes
   52016      Aconitase
   52021      Carbamoyl phosphate synthetase, small subunit N-terminal domain
   52029      GroEL apical domain-like
   52096      ClpP/crotonase
   52113      BRCT domain
   52121      Lumazine synthase
   52151      FabD/lysophospholipase-like
   52156      Initiation factor IF2/eIF5b, domain 3
   52172      CheY-like
   52218      Flavoproteins
   52283      Formate/glycerate dehydrogenase catalytic domain-like
   52304      Type II 3-dehydroquinate dehydratase
   52317      Class I glutamine amidotransferase-like
   52335      Methylglyoxal synthase-like
   52343      Ferredoxin reductase-like, C-terminal NADP-linked domain
   52374      Nucleotidylyl transferase
   52402      Adenine nucleotide alpha hydrolases-like
   52440      PreATP-grasp domain
   52467      DHS-like NAD/FAD-binding domain
   52490      Tubulin, GTPase domain
   52512      Phosphosugar isomerase
   52518      Thiamin diphosphate-binding fold (THDP-binding)
   52540      P-loop containing nucleotide triphosphate hydrolases
   52743      Subtilisin-like
   52777      CoA-dependent acyltransferases
   52821      Rhodanese/Cell cycle control phosphatase
   52833      Thioredoxin-like
   52922      TK C-terminal domain-like
   52935      Pyruvate kinase, C-terminal domain
   53041      Resolvase-like
   53067      Actin-like ATPase domain
   53098      Ribonuclease H-like
   53137      Translational machinery components
   53167      Purine and uridine phosphorylases
   53187      Zn-dependent exopeptidases
   53223      Aminoacid dehydrogenase-like, N-terminal domain
   53271      PRTase-like
   53300      vWA-like
   53323      Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
   53335      S-adenosyl-L-methionine-dependent methyltransferases
   53383      PLP-dependent transferases
   53448      Nucleotide-diphospho-sugar transferases
   53474      alpha/beta-Hydrolases
   53597      Dihydrofolate reductases
   53613      Ribokinase-like
   53671      Aspartate/ornithine carbamoyltransferase
   53697      SIS domain
   53706      Formate dehydrogenase/DMSO reductase, domains 1-3
   53732      Aconitase iron-sulfur domain
   53738      Phosphoglucomutase, first 3 domains
   53748      Phosphoglycerate kinase
   53795      PEP carboxykinase-like
   53822      Periplasmic binding protein-like I
   53850      Periplasmic binding protein-like II
   53901      Thiolase-like
   54001      Cysteine proteinases
   54160      Chromo domain-like
   54197      HIT-like
   54211      Ribosomal protein S5 domain 2-like
   54236      Ubiquitin-like
   54292      2Fe-2S ferredoxin-like
   54373      FAD-linked reductases, C-terminal domain
   54427      NTF2-like
   54452      MHC antigen-recognition domain
   54495      UBC-like
   54570      Ribosomal protein S19
   54593      Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
   54637      Thioesterase/thiol ester dehydrase-isomerase
   54713      Elongation factor Ts (EF-Ts), dimerisation domain
   54719      Fe,Mn superoxide dismutase (SOD), C-terminal domain
   54736      ClpS-like
   54791      Eukaryotic type KH-domain (eKH-domain)
   54810      GMP synthetase C-terminal dimerisation domain
   54826      Enolase N-terminal domain-like
   54849      GroEL-intermediate domain like
   54862      4Fe-4S ferredoxins
   54966      RuBisCO, large subunit, small (N-terminal) domain
   54980      EF-G/eEF-2 domains III and V
   54984      eEF-1beta-like
   55073      Adenylyl and guanylyl cyclase catalytic domain
   55083      6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
   55129      Ribosomal protein L30p/L7e
   55159      eIF1-like
   55194      Ribosome recycling factor, RRF
   55287      RPB5-like RNA polymerase subunit
   55307      Tubulin, C-terminal domain
   55315      L30e-like
   55347      Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
   55418      Translation initiation factor eIF4e
   55424      FAD/NAD-linked reductases, dimerisation (C-terminal) domain
   55469      NADH oxidase/flavin reductase
   55481      N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
   55620      Tetrahydrobiopterin biosynthesis enzymes-like
   55666      Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
   55729      Acyl-CoA N-acyltransferases (Nat)
   55753      Actin depolymerizing proteins
   55770      Profilin (actin-binding protein)
   55831      Thymidylate synthase/dCMP hydroxymethylase
   55874      ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
   55920      Creatinase/aminopeptidase
   55945      TATA-box binding protein-like
   55957      Phosphoglucomutase, C-terminal domain
   55973      S-adenosylmethionine synthetase
   55979      DNA clamp
   56019      The spindle assembly checkpoint protein mad2
   56047      Ribosomal protein S8
   56053      Ribosomal protein L6
   56059      Glutathione synthetase ATP-binding domain-like
   56091      DNA ligase/mRNA capping enzyme, catalytic domain
   56112      Protein kinase-like (PK-like)
   56235      N-terminal nucleophile aminohydrolases (Ntn hydrolases)
   56276      S-adenosylmethionine decarboxylase
   56295      Protein serine/threonine phosphatase 2
   56300      Metallo-dependent phosphatases
   56327      Lactate & malate dehydrogenases, C-terminal domain
   56349      DNA breaking-rejoining enzymes
   56420      Peptide deformylase
   56425      Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
   56487      Scavenger receptor cysteine-rich (SRCR) domain
   56634      Heme-linked catalases
   56655      Sugar phosphatases
   56719      Type II DNA topoisomerase
   56741      Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
   56752      D-aminoacid aminotransferase-like PLP-dependent enzymes
   56778      Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
   56801      Firefly luciferase-like
   56808      Ribosomal protein L1
   56815      Sec1/munc18-like (SM) proteins
   56935      Porins
   56959      Leukocidin (pore-forming toxin)
   57184      Growth factor receptor domain
   57196      EGF/Laminin
   57440      Kringle-like
   57467      Ovomucoid/PCI-1 like inhibitors
   57716      Glucocorticoid receptor-like (DNA-binding domain)
   57774      Microbial and mitochondrial ADK, insert "zinc finger" domain
   57850      RING finger domain, C3HC4
   57863      Pyk2-associated protein beta ARF-GAP domain
   57903      FYVE/PHD zinc finger
   57938      Cysteine-rich domain of the chaperone protein DnaJ.
   63380      Riboflavin synthase domain-like
   63393      RBP12 subunit of RNA polymerase II
   63411      LuxS/MPP-like metallohydrolase
   64356      SNARE-like
   68923      PEP carboxykinase N-terminal domain
   69047      Hypothetical protein YjbJ
   69055      1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
   69336      Alpha subunit of glutamate synthase, C-terminal domain
   69349      Phage fibre proteins
   69765      2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
   69848      LCCL domain
   74748      Variable surface antigen VlsE
   74778      Aconitase B, N-terminal domain
   74877      Major surface antigen p30, SAG1
   75520      Clathrin coat assembly domain
   81606      Protein serine/threonine phosphatase 2C, catalytic domain
   81653      Calcium ATPase, transduction domain A
   81660      Calcium ATPase, ATP-binding domain N
   81811      Helical domain of Sec23/24
   81923      Double Clp-N motif
   82051      Obg GTP-binding protein N-terminal domain
   82649      SufE (YhnA)
   82754      C-terminal, gelsolin-like domain of Sec23/24
   82895      TSP-1 type 1 repeat
   82910      Apical membrane antigen 1