SCOP Superfamily code |     | No of sequences |      | Superfamily name |
| 46458 |     |     3 |    | Globin-like |
| 46548 |     |     2 |    | alpha-helical ferredoxin |
| 46561 |     |     2 |    | Ribosomal protein L29 (L29p) |
| 46585 |     |     2 |    | Effector domain of the protein kinase pkn/prk1 |
| 46609 |     |     4 |    | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| 46626 |     |     2 |    | Cytochrome c |
| 46689 |     |     8 |    | Homeodomain-like |
| 46785 |     |     22 |    | "Winged helix" DNA-binding domain |
| 46906 |     |     2 |    | Ribosomal protein L11, C-terminal domain |
| 46911 |     |     2 |    | Ribosomal protein S18 |
| 46946 |     |     3 |    | S13-like H2TH domain |
| 46950 |     |     6 |    | Hypothetical protein MTH1615 |
| 46966 |     |     2 |    | Spectrin repeat |
| 47055 |     |     2 |    | TAF(II)230 TBP-binding fragment |
| 47060 |     |     2 |    | S15/NS1 RNA-binding domain |
| 47095 |     |     4 |    | HMG-box |
| 47113 |     |     17 |    | Histone-fold |
| 47240 |     |     3 |    | Ferritin-like |
| 47370 |     |     2 |    | Bromodomain |
| 47473 |     |     9 |    | EF-hand |
| 47576 |     |     2 |    | Calponin-homology domain, CH-domain |
| 47616 |     |     24 |    | Glutathione S-transferase (GST), C-terminal domain |
| 47644 |     |     2 |    | Methionine synthase domain |
| 47694 |     |     2 |    | Cytochrome c oxidase subunit h |
| 47699 |     |     127 |    | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| 47781 |     |     2 |    | RuvA domain 2-like |
| 47789 |     |     2 |    | C-terminal domain of RNA polymerase alpha subunit |
| 47836 |     |     1 |    | Retroviral matrix proteins |
| 47857 |     |     2 |    | Apolipophorin-III |
| 47874 |     |     2 |    | Annexin |
| 47895 |     |     3 |    | Transducin (alpha subunit), insertion domain |
| 47917 |     |     5 |    | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| 47928 |     |     2 |    | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| 47954 |     |     4 |    | Cyclin-like |
| 47973 |     |     3 |    | Ribosomal protein S7 |
| 47986 |     |     2 |    | DEATH domain |
| 48056 |     |     8 |    | Di-copper centre-containing domain |
| 48065 |     |     3 |    | DBL homology domain (DH-domain) |
| 48113 |     |     9 |    | Heme-dependent peroxidases |
| 48140 |     |     2 |    | Ribosomal protein L19 (L19e) |
| 48201 |     |     2 |    | Uteroglobin-like |
| 48208 |     |     3 |    | Six-hairpin glycosyltransferases |
| 48264 |     |     22 |    | Cytochrome P450 |
| 48329 |     |     1 |    | RNA polymerase sigma subunit |
| 48334 |     |     2 |    | DNA repair protein MutS, domain III |
| 48371 |     |     2 |    | ARM repeat |
| 48403 |     |     7 |    | Ankyrin repeat |
| 48445 |     |     4 |    | 14-3-3 protein |
| 48452 |     |     6 |    | TPR-like |
| 48484 |     |     1 |    | Lipoxigenase |
| 48503 |     |     3 |    | Skp1-Skp2 dimerisation domains |
| 48557 |     |     3 |    | L-aspartase-like |
| 48592 |     |     3 |    | GroEL equatorial domain-like chaperone equatorial domain |
| 49265 |     |     1 |    | Fibronectin type III |
| 49329 |     |     3 |    | Cu,Zn superoxide dismutase-like |
| 49384 |     |     1 |    | Carbohydrate-binding domain |
| 49441 |     |     2 |    | Cytochrome f, large domain |
| 49503 |     |     7 |    | Cupredoxins |
| 49562 |     |     2 |    | C2 domain (Calcium/lipid-binding domain, CaLB) |
| 49590 |     |     22 |    | PHL pollen allergen |
| 49594 |     |     2 |    | Rab geranylgeranyltransferase alpha-subunit, insert domain |
| 49611 |     |     1 |    | Viral coat and capsid proteins |
| 49695 |     |     2 |    | gamma-Crystallin-like |
| 49764 |     |     11 |    | HSP20-like chaperones |
| 49777 |     |     4 |    | PEBP-like |
| 49870 |     |     7 |    | Osmotin, thaumatin-like protein |
| 49899 |     |     3 |    | Concanavalin A-like lectins/glucanases |
| 50022 |     |     2 |    | ISP domain |
| 50104 |     |     3 |    | Translation proteins SH3-like domain |
| 50129 |     |     2 |    | GroES-like |
| 50156 |     |     3 |    | PDZ domain-like |
| 50193 |     |     3 |    | Ribosomal protein L14 |
| 50249 |     |     7 |    | Nucleic acid-binding proteins |
| 50324 |     |     1 |    | Inorganic pyrophosphatase |
| 50386 |     |     2 |    | STI-like |
| 50447 |     |     2 |    | Translation proteins |
| 50465 |     |     3 |    | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |
| 50494 |     |     1 |    | Trypsin-like serine proteases |
| 50615 |     |     5 |    | N-terminal domain of alpha and beta subunits of F1 ATP synthase |
| 50685 |     |     7 |    | Barwin-like endoglucanases |
| 50729 |     |     2 |    | PH domain-like |
| 50814 |     |     2 |    | Lipocalins |
| 50882 |     |     2 |    | Metalloprotease inhibitor |
| 50891 |     |     9 |    | Cyclophilin (peptidylprolyl isomerase) |
| 50960 |     |     1 |    | TolB, C-terminal domain |
| 50978 |     |     3 |    | WD40-repeat |
| 51004 |     |     1 |    | C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase |
| 51011 |     |     3 |    | alpha-Amylases, C-terminal beta-sheet domain |
| 51045 |     |     18 |    | WW domain |
| 51101 |     |     5 |    | Mannose-binding lectins |
| 51126 |     |     3 |    | Pectin lyase-like |
| 51161 |     |     7 |    | Trimeric LpxA-like enzymes |
| 51182 |     |     10 |    | RmlC-like cupins |
| 51197 |     |     4 |    | Clavaminate synthase-like |
| 51206 |     |     2 |    | cAMP-binding domain-like |
| 51230 |     |     2 |    | Single hybrid motif |
| 51246 |     |     4 |    | Rudiment single hybrid motif |
| 51316 |     |     2 |    | Mss4-like |
| 51344 |     |     2 |    | Epsilon subunit of F1F0-ATP synthase N-terminal domain |
| 51351 |     |     2 |    | Triosephosphate isomerase (TIM) |
| 51366 |     |     3 |    | Ribulose-phoshate binding barrel |
| 51395 |     |     1 |    | FMN-linked oxidoreductases |
| 51430 |     |     2 |    | NAD(P)-linked oxidoreductase |
| 51445 |     |     10 |    | (Trans)glycosidases |
| 51569 |     |     5 |    | Aldolase |
| 51649 |     |     3 |    | RuBisCo, C-terminal domain |
| 51717 |     |     3 |    | Dihydropteroate synthetase-like |
| 51735 |     |     8 |    | NAD(P)-binding Rossmann-fold domains |
| 52009 |     |     1 |    | Phosphohistidine domain |
| 52025 |     |     1 |    | Transferrin receptor ectodomain, apical domain |
| 52029 |     |     4 |    | GroEL apical domain-like |
| 52047 |     |     1 |    | RNI-like |
| 52058 |     |     18 |    | L domain-like |
| 52096 |     |     5 |    | ClpP/crotonase |
| 52121 |     |     1 |    | Lumazine synthase |
| 52141 |     |     1 |    | DNA glycosylase |
| 52172 |     |     2 |    | CheY-like |
| 52218 |     |     4 |    | Flavoproteins |
| 52279 |     |     3 |    | Beta-D-glucan exohydrolase, C-terminal domain |
| 52283 |     |     3 |    | Formate/glycerate dehydrogenase catalytic domain-like |
| 52313 |     |     2 |    | Ribosomal protein S2 |
| 52317 |     |     1 |    | Class I glutamine amidotransferase-like |
| 52343 |     |     5 |    | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| 52402 |     |     1 |    | Adenine nucleotide alpha hydrolases-like |
| 52440 |     |     8 |    | PreATP-grasp domain |
| 52467 |     |     9 |    | DHS-like NAD/FAD-binding domain |
| 52490 |     |     6 |    | Tubulin, GTPase domain |
| 52518 |     |     4 |    | Thiamin diphosphate-binding fold (THDP-binding) |
| 52540 |     |     27 |    | P-loop containing nucleotide triphosphate hydrolases |
| 52728 |     |     2 |    | Fructose permease, subunit IIb |
| 52799 |     |     1 |    | (Phosphotyrosine protein) phosphatases II |
| 52821 |     |     4 |    | Rhodanese/Cell cycle control phosphatase |
| 52833 |     |     39 |    | Thioredoxin-like |
| 52954 |     |     2 |    | Anticodon-binding domain of Class II aaRS |
| 53067 |     |     4 |    | Actin-like ATPase domain |
| 53137 |     |     2 |    | Translational machinery components |
| 53187 |     |     2 |    | Zn-dependent exopeptidases |
| 53223 |     |     2 |    | Aminoacid dehydrogenase-like, N-terminal domain |
| 53271 |     |     2 |    | PRTase-like |
| 53335 |     |     9 |    | S-adenosyl-L-methionine-dependent methyltransferases |
| 53383 |     |     7 |    | PLP-dependent transferases |
| 53448 |     |     11 |    | Nucleotide-diphospho-sugar transferases |
| 53474 |     |     7 |    | alpha/beta-Hydrolases |
| 53597 |     |     2 |    | Dihydrofolate reductases |
| 53613 |     |     3 |    | Ribokinase-like |
| 53649 |     |     1 |    | Alkaline phosphatase-like |
| 53671 |     |     2 |    | Aspartate/ornithine carbamoyltransferase |
| 53686 |     |     2 |    | Tryptophan synthase beta subunit-like PLP-dependent enzymes |
| 53720 |     |     5 |    | ALDH-like |
| 53738 |     |     2 |    | Phosphoglucomutase, first 3 domains |
| 53748 |     |     5 |    | Phosphoglycerate kinase |
| 53784 |     |     1 |    | Phosphofructokinase |
| 53850 |     |     3 |    | Periplasmic binding protein-like II |
| 53901 |     |     6 |    | Thiolase-like |
| 53955 |     |     9 |    | Lysozyme-like |
| 54001 |     |     6 |    | Cysteine proteinases |
| 54076 |     |     2 |    | RNase A-like |
| 54160 |     |     6 |    | Chromo domain-like |
| 54171 |     |     10 |    | DNA-binding domain |
| 54189 |     |     2 |    | Ribosomal proteins L23 and L15e |
| 54211 |     |     2 |    | Ribosomal protein S5 domain 2-like |
| 54236 |     |     3 |    | Ubiquitin-like |
| 54292 |     |     4 |    | 2Fe-2S ferredoxin-like |
| 54368 |     |     2 |    | Glutamine synthetase, N-terminal domain |
| 54403 |     |     7 |    | Cystatin/monellin |
| 54495 |     |     5 |    | UBC-like |
| 54534 |     |     3 |    | FKBP-like |
| 54565 |     |     2 |    | Ribosomal protein S16 |
| 54570 |     |     2 |    | Ribosomal protein S19 |
| 54593 |     |     1 |    | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| 54637 |     |     1 |    | Thioesterase/thiol ester dehydrase-isomerase |
| 54654 |     |     2 |    | CI-2 family of serine protease inhibitors |
| 54686 |     |     2 |    | Ribosomal protein L10e |
| 54695 |     |     2 |    | POZ domain |
| 54719 |     |     4 |    | Fe,Mn superoxide dismutase (SOD), C-terminal domain |
| 54747 |     |     2 |    | Ribosomal protein L11, N-terminal domain |
| 54782 |     |     2 |    | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain |
| 54814 |     |     2 |    | Prokaryotic type KH domain (pKH-domain) |
| 54821 |     |     4 |    | Ribosomal protein S3 C-terminal domain |
| 54843 |     |     4 |    | Ribosomal protein L22 |
| 54849 |     |     2 |    | GroEL-intermediate domain like |
| 54862 |     |     5 |    | 4Fe-4S ferredoxins |
| 54928 |     |     49 |    | RNA-binding domain, RBD |
| 54966 |     |     4 |    | RuBisCO, large subunit, small (N-terminal) domain |
| 54980 |     |     2 |    | EF-G/eEF-2 domains III and V |
| 54984 |     |     2 |    | eEF-1beta-like |
| 55035 |     |     6 |    | NAD-binding domain of HMG-CoA reductase |
| 55159 |     |     2 |    | eIF1-like |
| 55174 |     |     2 |    | Alpha-L RNA-binding motif |
| 55239 |     |     6 |    | RuBisCO, small subunit |
| 55257 |     |     1 |    | RBP11-like subunits of RNA polymerase |
| 55271 |     |     2 |    | DNA repair protein MutS, domain I |
| 55282 |     |     3 |    | Ribosomal protein L5 |
| 55307 |     |     7 |    | Tubulin, C-terminal domain |
| 55315 |     |     1 |    | L30e-like |
| 55405 |     |     2 |    | RNA bacteriophage capsid protein |
| 55418 |     |     4 |    | Translation initiation factor eIF4e |
| 55455 |     |     4 |    | SRF-like |
| 55637 |     |     2 |    | Cell cycle regulatory proteins |
| 55648 |     |     1 |    | beta-lactamase-inhibitor protein, BLIP |
| 55653 |     |     2 |    | Ribosomal protein L9 C-domain |
| 55658 |     |     2 |    | L9 N-domain-like |
| 55681 |     |     3 |    | Class II aaRS and biotin synthetases |
| 55729 |     |     3 |    | Acyl-CoA N-acyltransferases (Nat) |
| 55753 |     |     3 |    | Actin depolymerizing proteins |
| 55770 |     |     4 |    | Profilin (actin-binding protein) |
| 55797 |     |     5 |    | PR-1-like |
| 55856 |     |     2 |    | Cytochrome b5 |
| 55874 |     |     5 |    | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| 55895 |     |     4 |    | Ribonuclease Rh-like |
| 55920 |     |     8 |    | Creatinase/aminopeptidase |
| 55931 |     |     5 |    | Glutamine synthase/guanido kinase |
| 55945 |     |     4 |    | TATA-box binding protein-like |
| 55957 |     |     2 |    | Phosphoglucomutase, C-terminal domain |
| 56029 |     |     1 |    | Monooxygenase (hydroxylase) regulatory protein |
| 56047 |     |     2 |    | Ribosomal protein S8 |
| 56053 |     |     3 |    | Ribosomal protein L6 |
| 56059 |     |     5 |    | Glutathione synthetase ATP-binding domain-like |
| 56112 |     |     59 |    | Protein kinase-like (PK-like) |
| 56204 |     |     1 |    | Ubiquitin-protein ligase E3a, Hect catalytic domain (E6ap) |
| 56235 |     |     4 |    | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| 56276 |     |     2 |    | S-adenosylmethionine decarboxylase |
| 56327 |     |     4 |    | Lactate & malate dehydrogenases, C-terminal domain |
| 56349 |     |     1 |    | DNA breaking-rejoining enzymes |
| 56371 |     |     2 |    | Ribosome inactivating proteins (RIP) |
| 56436 |     |     3 |    | C-type lectin-like |
| 56542 |     |     2 |    | Substrate-binding domain of HMG-CoA reductase |
| 56553 |     |     2 |    | Insert subdomain of RNA polymerase alpha subunit |
| 56574 |     |     6 |    | Serpins |
| 56601 |     |     1 |    | beta-Lactamase/D-ala carboxypeptidase |
| 56629 |     |     1 |    | ADP ribosyl cyclase-like |
| 56634 |     |     3 |    | Heme-linked catalases |
| 56655 |     |     3 |    | Sugar phosphatases |
| 56752 |     |     1 |    | D-aminoacid aminotransferase-like PLP-dependent enzymes |
| 56762 |     |     2 |    | Nickel-iron hydrogenase, large subunit |
| 56770 |     |     1 |    | Nickel-iron hydrogenase, small subunit |
| 56778 |     |     3 |    | Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment |
| 57016 |     |     8 |    | Plant lectins/antimicrobial peptides |
| 57095 |     |     5 |    | Scorpion toxin-like |
| 57196 |     |     3 |    | EGF/Laminin |
| 57247 |     |     3 |    | Bowman-Birk inhibitor, BBI |
| 57302 |     |     2 |    | Snake toxin-like |
| 57429 |     |     5 |    | Crambin-like |
| 57501 |     |     2 |    | Cystine-knot cytokines |
| 57598 |     |     2 |    | Antifungal protein (AGAFP) |
| 57716 |     |     3 |    | Glucocorticoid receptor-like (DNA-binding domain) |
| 57756 |     |     4 |    | Retrovirus zinc finger-like domains |
| 57840 |     |     2 |    | Ribosomal protein L36 |
| 57850 |     |     3 |    | RING finger domain, C3HC4 |
| 57903 |     |     3 |    | FYVE/PHD zinc finger |
| 63380 |     |     4 |    | Riboflavin synthase domain-like |
| 63491 |     |     2 |    | BAG domain |
| 63570 |     |     2 |    | PABC (PABP) domain |
| 63887 |     |     1 |    | P-domain of calnexin/calreticulin |
| 64158 |     |     2 |    | 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain |
| 64356 |     |     2 |    | SNARE-like |
| 68993 |     |     2 |    | FAT domain of focal adhesion kinase |
| 69279 |     |     2 |    | Phage tail proteins |
| 69304 |     |     2 |    | Tricorn protease N-terminal domain |
| 69572 |     |     4 |    | Molybdenum cofactor biosynthesis protein MoeB |
| 69737 |     |     3 |    | Urease metallochaperone UreE, C-terminal domain |
| 74731 |     |     2 |    | Ribosomal protein L20 |
| 75005 |     |     2 |    | alpha-L-arabinanase |
| 75604 |     |     1 |    | Archaeosine tRNA-guanine transglycosylase, C-terminal additional domains |
| 75689 |     |     2 |    | Zinc-binding domain of translation initiation factor 2 beta |
| 81271 |     |     2 |    | TGS-like |
| 81296 |     |     5 |    | E set domains |
| 81382 |     |     3 |    | Skp1 dimerisation domain-like |
| 81383 |     |     1 |    | F-box domain |
| 81653 |     |     1 |    | Calcium ATPase, transduction domain A |
| 81660 |     |     1 |    | Calcium ATPase, ATP-binding domain N |
| 81736 |     |     4 |    | Pollen allergen Phl P 6 |
| 81783 |     |     2 |    | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| 81923 |     |     4 |    | Double Clp-N motif |
| 81986 |     |     1 |    | Tp47 lipoprotein, middle and C-terminal domains |
| 82199 |     |     3 |    | SET domain |
| 82607 |     |     2 |    | YbaB-like |
| 82657 |     |     2 |    | BolA-like |
| 82693 |     |     2 |    | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 82829 |     |     1 |    | Putative cell cycle protein MesJ, middle and C-terminal domain |
| 82931 |     |     3 |    | Tumor suppressor gene product Apc |