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Protein Alignments organised as Structural Superfamilies


Superfamily :     Inosine monophosphate dehydrogenase (IMPDH)
Class :    Alpha and beta proteins (a/b)
Fold :    TIM beta/alpha-barrel
Number of Members :     3
Average Size :     343


Alignment Matrices Tree Genome Distribution HMM Interacting Motifs

Protein
Code		 Start
Residue		 Start
Chain		 End
Residue		 End
Chain		 Domain
Size		 Name Source Resolution R-factor
1ak5-1 2 - 483 - 329 inosine-5'-monophosphate dehydrogenase tritrichomonas foetus 2.3 0.218
1jr1a1 17 A 514 A 362 inosine-5'-monophosphate dehydrogenase 2 cricetulus griseus 2.60 0.217
1zfja1 2 A 491 A 340 inosine monophosphate dehydrogenase streptococcus pyogenes 1.90 0.232

| pir | postscript | superposed-coordinates |

Alignment Based On Similarities In Structural Features (COMPARER Alignment) 



 
1ak5-1  (   2 )         akyynepchtFneylLipglstvdÇipsnVnLsTpLVkfqkgqqS
1jr1a1  (  17 )    gltAqqLFncgdgltYndFlilpgyid--FtadqVdLtSaLTk-------
1zfja1  (   2 )    s--nwdtkflkkGytFddVllipaesh--vlpnevdLktkLad-------
                                  333 bb          333    bb          
 


    
1ak5-1  (  47 )    einLkiPLVSaImqSVSgekMAIaLAreGGISFIfgsqsiesQaamVhaV
1jr1a1  (  58 )    kitLkTPLVSSPmdtVTeagMAiAMALtGGIGFIHhnctpefQanEVrkV
1zfja1  (  41 )    nLtLnIPIItaa-dTVTgsk-AiaIAragGLGvIhkn-siteQAeeVrkV
                     bb    bb            aaaa    bbbb     aaaaaaaaaaa
 


    
1ak5-1  (  97 )    Knfka-hneLvdsqkrYlVGAGIntr-dFreRVpaLveagAdVLCIdssd
1jr1a1  ( 108 )    KkyeqyplAskdakkqLlCGAAIgtheddkyrLdlLalagVdVVVLdssq
1zfja1  (  91 )    Krse----------grllVAAAVgvtsdTferAeaLFeAgAdAIVIdtah
                   a                  bbbb     aaaaaaaaaaa   bbbb    
 


    
1ak5-1  ( 265 )    GfsewQkiTIgwIrekygdkvkVGAGNIvdgeGFryLAdAgADFIKIGi-
1jr1a1  ( 278 )    GnsifQinMIkyMkekyp-nlqVIGGnVvtaaqAknLidAgVdALrVGmG
1zfja1  ( 257 )    GhsagVlrkIaeIrahfp-nrTLIAGnIataeGAraLYdagVdVVkVGiG
                      aaaaaaaaaaaaa      bbbbbb  aaaaaaaaa    bbbb   
 


    
1ak5-1  ( 328 )    -------------grgqAtAVidVvaeRnkyfeetgiyIPVCSdggIvyd
1jr1a1  ( 327 )    cgsiciTqevlacGrpQAtAVYkVSeyArrf------gVpVIAdggIqnv
1zfja1  ( 306 )    pgsicttrvvagvgvpQVtAIydAaaVArey------gktIiAdggIkys
                                   aaaaaaaaaaaa            bbb      a
 


    
1ak5-1  ( 365 )    yHMTLALAMgADFIMLgryFArFeeSpTrkvtingsvmKeywgegSs---
1jr1a1  ( 371 )    gHIakALALGAsTVMMgslLAATteApgeyffsdgirlKkYrGmgSldAm
1zfja1  ( 350 )    gDiVkALAAgGnAV-lgs-FAGTdeApGeteiyqgrkyktyrg-gSiaak
                   aaaaaaaa                      bb    bbbbbb        
 


    
1ak5-1  ( 412 )    ------rgvdsyvpyagkLkdnVeaSlnkVkstMçnCGAltIpqLqsk--
1jr1a1  ( 437 )    i--kvaqGvsgavqdkgsIhkfVpyLiagIqhsCqdiGAksLtqVramMy
1zfja1  ( 401 )    knklvpeGiegrvaykgaasdiVfql-ggIrsgG-yVGagdiqelhen--
                            bbbbb    aaaaaa   aaaaa         aaaaaaa  
 


    
1ak5-1  ( 473 )    ---Akitlvssvsi                  
1jr1a1  ( 485 )    sgeLkFekrtssaqveggvhslhsyekrlf  
1zfja1  ( 463 )    ---Aqfve-sgaglieshphdvqitneapnys
                        bb                         
 


    
 


Key
solvent inaccessible                    UPPER CASE      X
solvent accesible                       lower case      x
alpha helix                             red             x
beta strand				blue            x
3 - 10 helix				maroon          x
hydrogen bond to main chain amide    	bold            x
hydrogen bond to mainchain carbonyl     underline	x
disulphide bond                         cedilla         ç
positive phi				italic		x


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