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Protein Alignments organised as Structural Superfamilies


Superfamily :     Triosephosphate isomerase (TIM)
Class :    Alpha and beta proteins (a/b)
Fold :    TIM beta/alpha-barrel
Number of Members :     3
Average Size :     243


Alignment Matrices Tree Genome Distribution HMM Interacting Motifs

Protein
Code		 Start
Residue		 Start
Chain		 End
Residue		 End
Chain		 Domain
Size		 Name Source Resolution R-factor
1amk-- 1 - 250 - 250 triose phosphate isomerase leishmania mexicana 1.83 0.107
1aw1a- 2 A 256 A 255 triosephosphate isomerase vibrio marinus 2.7 0.192
1hg3a- 2 A 225 A 224 triosephosphate isomerase pyrococcus woesei 2.7 0.254

| pir | postscript | superposed-coordinates |

Alignment Based On Similarities In Structural Features (COMPARER Alignment) 



 
1amk--  (   1 )    sakpqpIAAAnWkcn--gttasIeklVqvFneh--tIshdVqCVVAPtfv
1aw1a-  (   2 )       rhPVVMGNWkln--GskemVvdlLngLnaelegvt-gVdVAVAPpal
1hg3a-  (   2 )    aklkepIIAINFktyieAtgkrAleIAkaAekVyk--etgvtIVVAPqlv
                         bbbbb        aaaaaaaaaaaa          bbbbb    
 


    
1amk--  (  47 )    hIplVqakL--rNpkYviSAenAiak-sgaftgevSMpiLkdigVhWVIL
1aw1a-  (  46 )    fVdlAertlteagSaIiLGAqnTdlnnsgaftgdmSPamLkefgAthIII
1hg3a-  (  50 )    dLrmIAesV-----eIpVFAqhIdpikpgshtghvlPeaVkeagAvGTLL
                    aaaaaa                             aaaa      bbbb
 


    
1amk--  (  94 )    GhserrtyygetdeiVAqkVseACkqgFmVIACIGEtlqqreanqtakvV
1aw1a-  (  96 )    GHserreyhaEsdefVakKFafLkengLtPVLCIGEsdaqneagetmaVC
1hg3a-  (  95 )    nhsen----rmiladLeaAIrrAeevgLmTMVCSnn----------pavS
                               aaaaaaaaaaaaa   bbbbbb            aaaa
 


    
1amk--  ( 144 )    lsqTsaIaakLtkdaWnqVVLAYEPvwAigtgkvAtpeqAqevHllLrkw
1aw1a-  ( 146 )    arqLdaVIntqgveaLegAIIAYEPiwAigtgkaAtAedAqrIHaqIrah
1hg3a-  ( 131 )    aaVAal----------nPdYVAVEPpeligtgipV-SkakpevItnTvel
                   aaaa               bbbb                  aaaaaaaaa
 


    
1amk--  ( 194 )    VsenigtdvAakLrILYGgsVn-aanAatLyakpdINGFLVggaSlkp-e
1aw1a-  ( 196 )    Iae-kseavAknVvIQYGGsVk-penAaaYFaqpdIDGALVggaAldaks
1hg3a-  ( 170 )    Vkkvn-----peVkVLCGAgIstGeDVkkAie-lgTvGVLLAsgVTkakd
                   aa            bbb         aaaaa      bbbb         
 


    
1amk--  ( 242 )    FrdIIdaTr    
1aw1a-  ( 244 )    FAaIAkaAaeaka
1hg3a-  ( 214 )    pekaIwdLVsgi 
                   aaaaaa       
 


    
 


Key
solvent inaccessible                    UPPER CASE      X
solvent accesible                       lower case      x
alpha helix                             red             x
beta strand				blue            x
3 - 10 helix				maroon          x
hydrogen bond to main chain amide    	bold            x
hydrogen bond to mainchain carbonyl     underline	x
disulphide bond                         cedilla         ç
positive phi				italic		x


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